iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074429

Ensembl Protein ID

ENSOCUP00000015557.1

UniProt Accession

G1TF67; G1TF67_RABIT

Genbank Protein ID

ENSOCUP00000015557

Protein Name

Coronin

Genbank Nucleotide ID

AAGW02069665

Gene Name

CORO1A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000002253.3	ENSOCUT00000024625.1	ENSOCUP00000015557.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.50e-10	39.2	118	153

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           gHt +v  +a+ ++  + l+s++ D++i vWD+ tg
   Q: 118  GHTKRVGIVAWhPTaqNVLLSAGCDNVILVWDVGTG 153
           688888889***666799**************9887 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MSRQVVRSSK FRHVFGQPAK ADQCYEDVRV SQTTWDSGFC AVNPKFLALI CEASGGGAFL 60
VLPLCKVSPL GGLGPWLPYL GAPLHNDNVI ASALRTCERS LDGGLTLPLR EPVVTLEGHT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCCGGC AGGTGGTCCG CTCCAGCAAG TTCCGCCACG TGTTTGGACA GCCGGCCAAG 60
GCCGACCAGT GCTATGAGGA CGTGCGTGTC TCCCAGACCA CCTGGGACAG TGGCTTCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR029508--CORO1A
IPR015505--Coronin
IPR015048--DUF1899
IPR015049--Trimer_CC
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF08954--Trimer_CC
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0005884--C:actin filament
GO:0030424--C:axon
GO:0005911--C:cell-cell junction
GO:0030864--C:cortical actin cytoskeleton
GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0001772--C:immunological synapse
GO:0030027--C:lamellipodium
GO:0001891--C:phagocytic cup
GO:0045335--C:phagocytic vesicle
GO:0043234--C:protein complex
GO:0003723--F:RNA binding
GO:0007015--P:actin filament organization
GO:0006816--P:calcium ion transport
GO:0031589--P:cell-substrate adhesion
GO:0071353--P:cellular response to interleukin-4
GO:0061502--P:early endosome to recycling endosome transport
GO:0048873--P:homeostasis of number of cells within a tissue
GO:0030595--P:leukocyte chemotaxis
GO:0043320--P:natural killer cell degranulation
GO:0051126--P:negative regulation of actin nucleation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0031339--P:negative regulation of vesicle fusion
GO:0038180--P:nerve growth factor signaling pathway
GO:0001845--P:phagolysosome assembly
GO:0050918--P:positive chemotaxis
GO:0030335--P:positive regulation of cell migration
GO:0042102--P:positive regulation of T cell proliferation
GO:0008360--P:regulation of cell shape
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol
GO:0043029--P:T cell homeostasis
GO:0032796--P:uropod organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002012	Ailuropoda melanoleuca	86.33	0.00e+00	795.00
IUUC-Bta-013168	Bos taurus	86.12	0.00e+00	794.00
IUUC-Cja-019660	Callithrix jacchus	85.68	0.00e+00	793.00
IUUC-Cfa-020938	Canis familiaris	86.55	0.00e+00	797.00
IUUC-Cpo-022056	Cavia porcellus	85.03	0.00e+00	791.00
IUUC-Csa-023193	Chlorocebus sabaeus	85.25	0.00e+00	787.00
IUUC-Dno-029363	Dasypus novemcinctus	86.12	0.00e+00	793.00
IUUC-Dor-030426	Dipodomys ordii	86.15	0.00e+00	791.00
IUUC-Eca-034229	Equus caballus	84.60	0.00e+00	783.00
IUUC-Eeu-034499	Erinaceus europaeus	82.76	0.00e+00	663.00
IUUC-Fca-036472	Felis catus	85.47	0.00e+00	788.00
IUUC-Ggo-045162	Gorilla gorilla	85.03	0.00e+00	787.00
IUUC-Hsa-046874	Homo sapiens	85.03	0.00e+00	787.00
IUUC-Itr-048911	Ictidomys tridecemlineatus	86.12	0.00e+00	798.00
IUUC-Laf-053427	Loxodonta africana	86.12	0.00e+00	783.00
IUUC-Mcc-055750	Macaca mulatta	86.49	0.00e+00	736.00
IUUC-Meu-056083	Macropus eugenii	79.83	0.00e+00	738.00
IUUC-Mmr-060858	Microcebus murinus	85.90	0.00e+00	794.00
IUUC-Mdo-062469	Monodelphis domestica	81.44	0.00e+00	748.00
IUUC-Mmu-063583	Mus musculus	85.71	0.00e+00	791.00
IUUC-Mpu-066451	Mustela putorius furo	85.94	0.00e+00	760.00
IUUC-Mlu-066978	Myotis lucifugus	85.25	0.00e+00	785.00
IUUC-Nle-069815	Nomascus leucogenys	85.25	0.00e+00	788.00
IUUC-Opr-070911	Ochotona princeps	86.96	0.00e+00	806.00
IUUC-Oga-089072	Otolemur garnettii	84.45	0.00e+00	778.00
IUUC-Oar-089676	Ovis aries	85.90	0.00e+00	793.00
IUUC-Ptr-091647	Pan troglodytes	85.03	0.00e+00	787.00
IUUC-Pan-092672	Papio anubis	85.25	0.00e+00	787.00
IUUC-Pab-098348	Pongo abelii	80.04	0.00e+00	719.00
IUUC-Pva-102668	Pteropus vampyrus	85.47	0.00e+00	788.00
IUUC-Rno-105604	Rattus norvegicus	85.71	0.00e+00	791.00
IUUC-Sha-107210	Sarcophilus harrisii	80.69	0.00e+00	758.00
IUUC-Sar-113292	Sorex araneus	86.25	0.00e+00	639.00
IUUC-Tbe-128025	Tupaia belangeri	90.57	7.00e-126	442.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence