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Tag Content
UUCD2 ID IUUC-Cfa-021229
UUCD1 version UUC-CaF-00228
Ensembl Protein ID ENSCAFP00000030885.2
UniProt Accession E2R8H1; E2R8H1_CANLF
Genbank Protein ID ENSCAFP00000030885
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03004623
Gene Name MLST8
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000019407.3 ENSCAFT00000035607.2 ENSCAFP00000030885.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.50e-32 109.4 219 249
UBD/Beta-Prp 2.50e-44 152.0 129 322
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           Ht     ++f +d tll+++s D t+k+W++
   Q: 219  HTRYALQCRFsPDsTLLATCSADQTCKIWRT 249
           888888999**999***************96 PP
   

   UBD/Beta-Prp
   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls........tgkcvhtlk 91
           ++i+cv+ +p++  l++g ++g i +wd++t    + + + e  +t+  ++pd+++++ + + ++ +vw+l         +  +  ++ 
   Q: 129  APINCVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTggigdevtQLIPKTKIP 217
           699****************************8886666999999*************************99988777643333333444 PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllr 173
           +h++++l ++fsp++  l++ s+d+t ++w +++ + + e       + +  +g+ ++ ++++d++++v++s D+  rlW+++tg++ r
   Q: 218  AHTRYALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTElsikssnPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKR 306
           9*************************************99*****9999999************************************* PP
   S: 174  tltgghtdsvyslsfds 190
           +  g h+++v +l+f++
   Q: 307  EYGG-HQKAVVCLAFND 322
           **88.*********987 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MNTSPGTVGS DPVILATAGY DHTVRFWQAH SGICTRTVQH QDSQVNALEI TPDRSMIAAA 60
GYQHIRMYDL SSNNPNPIIS YDGVNKNIAS VGFHEDGRWM YTGGEDCTAR IWDLRSRNLQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-021229|E3,WD_repeat;UBD,Beta-Prp|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGACGCTCGG CCGCGGCCTC TATCGACTCG CTCCGGCTCC GCTCGCAGTC CTGGGCCGCG 60
GCGGAGCGCG GAGTCGCATG TAAGGTACGG GGGCCGCGGG ACGAGGGCCA GGAGACGGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-021229|E3,WD_repeat;UBD,Beta-Prp|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0031931--C:TORC1 complex
GO:0031932--C:TORC2 complex
GO:0043539--F:protein serine/threonine kinase activator activity
GO:0030838--P:positive regulation of actin filament polymerization
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0032008--P:positive regulation of TOR signaling
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity
GO:0031929--P:TOR signaling
GO:0038202--P:TORC1 signaling
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000595 Aegilops tauschii 49.52 3.00e-84 304.00
IUUC-Aml-001813 Ailuropoda melanoleuca 99.69 0.00e+00 680.00
IUUC-Atr-002512 Amborella trichopoda 46.98 2.00e-79 289.00
IUUC-Apl-003495 Anas platyrhynchos 90.49 2.00e-153 534.00
IUUC-Aca-004613 Anolis carolinensis 94.17 0.00e+00 651.00
IUUC-Aly-006340 Arabidopsis lyrata 45.66 3.00e-79 288.00
IUUC-Ath-007273 Arabidopsis thaliana 45.34 2.00e-78 285.00
IUUC-Ago-007737 Ashbya gossypii 47.44 2.00e-82 299.00
IUUC-Acl-008090 Aspergillus clavatus 48.52 4.00e-60 225.00
IUUC-Afl-008490 Aspergillus flavus 41.84 1.00e-40 160.00
IUUC-Afu-009060 Aspergillus fumigatus 46.43 3.00e-53 202.00
IUUC-Ani-009251 Aspergillus nidulans 48.31 3.00e-60 225.00
IUUC-Ang-009528 Aspergillus niger 45.94 5.00e-76 277.00
IUUC-Aor-010005 Aspergillus oryzae 44.08 3.00e-69 255.00
IUUC-Ate-010423 Aspergillus terreus 48.95 2.00e-60 226.00
IUUC-Ame-011752 Astyanax mexicanus 92.02 0.00e+00 644.00
IUUC-Bgr-012299 Blumeria graminis 42.44 2.00e-70 259.00
IUUC-Bta-013007 Bos taurus 99.06 0.00e+00 667.00
IUUC-Bci-013987 Botrytis cinerea 43.38 2.00e-75 276.00
IUUC-Bdi-014082 Brachypodium distachyon 49.21 6.00e-84 303.00
IUUC-Bol-015088 Brassica oleracea 45.98 3.00e-79 288.00
IUUC-Bra-016682 Brassica rapa 41.02 9.00e-69 253.00
IUUC-Cel-018473 Caenorhabditis elegans 25.60 3.00e-36 145.00
IUUC-Cja-019216 Callithrix jacchus 98.50 3.00e-158 550.00
IUUC-Cpo-022270 Cavia porcellus 99.69 0.00e+00 681.00
IUUC-Cre-022742 Chlamydomonas reinhardtii 47.96 2.00e-84 305.00
IUUC-Csa-023275 Chlorocebus sabaeus 99.08 0.00e+00 677.00
IUUC-Cin-025588 Ciona intestinalis 63.81 1.00e-127 449.00
IUUC-Csv-026252 Ciona savignyi 64.98 8.00e-131 459.00
IUUC-Cgl-026418 Colletotrichum gloeosporioides 46.03 7.00e-77 280.00
IUUC-Cne-027013 Cryptococcus neoformans 43.77 2.00e-72 265.00
IUUC-Cme-027131 Cyanidioschyzon merolae 32.16 9.00e-51 194.00
IUUC-Dre-028424 Danio rerio 91.72 0.00e+00 642.00
IUUC-Dno-029327 Dasypus novemcinctus 99.39 0.00e+00 679.00
IUUC-Dor-030186 Dipodomys ordii 99.38 6.00e-94 337.00
IUUC-Dse-031475 Dothistroma septosporum 43.98 2.00e-74 272.00
IUUC-Dme-031826 Drosophila melanogaster 49.21 3.00e-93 334.00
IUUC-Ete-032252 Echinops telfairi 84.14 4.00e-140 490.00
IUUC-Eca-033889 Equus caballus 99.16 2.00e-140 490.00
IUUC-Fca-035989 Felis catus 99.69 0.00e+00 681.00
IUUC-Fal-036637 Ficedula albicollis 93.87 0.00e+00 652.00
IUUC-Fox-038066 Fusarium oxysporum 46.98 4.00e-80 291.00
IUUC-Fso-038288 Fusarium solani 44.76 3.00e-74 271.00
IUUC-Gmo-039477 Gadus morhua 92.52 0.00e+00 638.00
IUUC-Ggr-039990 Gaeumannomyces graminis 46.54 6.00e-77 280.00
IUUC-Gga-040890 Gallus gallus 93.87 0.00e+00 652.00
IUUC-Gac-041502 Gasterosteus aculeatus 91.72 0.00e+00 640.00
IUUC-Gma-042985 Glycine max 47.62 7.00e-81 293.00
IUUC-Ggo-045629 Gorilla gorilla 98.78 0.00e+00 675.00
IUUC-Hsa-045824 Homo sapiens 98.61 1.00e-171 595.00
IUUC-Hvu-047767 Hordeum vulgare 49.21 4.00e-84 304.00
IUUC-Itr-047932 Ictidomys tridecemlineatus 99.69 0.00e+00 681.00
IUUC-Kpa-049173 Komagataella pastoris 46.15 7.00e-82 296.00
IUUC-Lch-049703 Latimeria chalumnae 93.87 0.00e+00 651.00
IUUC-Lpe-050744 Leersia perrieri 45.08 7.00e-73 267.00
IUUC-Loc-052507 Lepisosteus oculatus 91.72 0.00e+00 640.00
IUUC-Lma-053084 Leptosphaeria maculans 44.07 1.00e-72 266.00
IUUC-Laf-053595 Loxodonta africana 97.85 0.00e+00 669.00
IUUC-Mcc-055634 Macaca mulatta 84.70 0.00e+00 640.00
IUUC-Meu-055925 Macropus eugenii 94.10 4.00e-165 573.00
IUUC-Mor-057131 Magnaporthe oryzae 43.85 3.00e-77 281.00
IUUC-Mpo-057524 Magnaporthe poae 46.23 5.00e-77 280.00
IUUC-Mtr-057980 Medicago truncatula 47.30 7.00e-81 293.00
IUUC-Mla-059082 Melampsora laricipopulina 39.60 1.00e-61 229.00
IUUC-Mga-059552 Meleagris gallopavo 91.87 2.00e-155 540.00
IUUC-Mvi-060504 Microbotryum violaceum 43.12 1.00e-69 257.00
IUUC-Mdo-062886 Monodelphis domestica 95.09 0.00e+00 656.00
IUUC-Mmu-063477 Mus musculus 98.16 0.00e+00 673.00
IUUC-Mac-065439 Musa acuminata 48.25 3.00e-82 298.00
IUUC-Mpu-066708 Mustela putorius furo 99.39 0.00e+00 678.00
IUUC-Mlu-067311 Myotis lucifugus 96.14 0.00e+00 667.00
IUUC-Nfi-068294 Neosartorya fischeri 46.26 9.00e-54 204.00
IUUC-Ncr-068811 Neurospora crassa 44.44 6.00e-75 274.00
IUUC-Nle-069632 Nomascus leucogenys 99.39 0.00e+00 679.00
IUUC-Opr-071128 Ochotona princeps 96.34 1.00e-109 388.00
IUUC-Ont-071494 Oreochromis niloticus 92.64 0.00e+00 645.00
IUUC-Oan-073298 Ornithorhynchus anatinus 93.12 8.00e-105 372.00
IUUC-Ocu-073983 Oryctolagus cuniculus 98.77 0.00e+00 674.00
IUUC-Oba-076001 Oryza barthii 44.44 3.00e-72 264.00
IUUC-Obr-076833 Oryza brachyantha 47.30 2.00e-80 291.00
IUUC-Ogl-077680 Oryza glaberrima 47.30 2.00e-80 291.00
IUUC-Ogu-078086 Oryza glumaepatula 43.33 3.00e-72 265.00
IUUC-Oin-079336 Oryza indica 47.30 2.00e-80 291.00
IUUC-Olo-080368 Oryza longistaminata 42.25 1.00e-58 219.00
IUUC-Oni-083046 Oryza nivara 44.44 3.00e-72 265.00
IUUC-Opu-084173 Oryza punctata 44.44 3.00e-72 264.00
IUUC-Oru-084599 Oryza rufipogon 44.44 3.00e-72 264.00
IUUC-Osa-086193 Oryza sativa 47.30 2.00e-80 291.00
IUUC-Ola-087216 Oryzias latipes 92.02 0.00e+00 644.00
IUUC-Olu-087852 Ostreococcus lucimarinus 46.98 5.00e-81 294.00
IUUC-Oga-088840 Otolemur garnettii 98.48 0.00e+00 674.00
IUUC-Oar-089294 Ovis aries 98.27 2.00e-171 594.00
IUUC-Ptr-090565 Pan troglodytes 99.39 0.00e+00 679.00
IUUC-Pan-092175 Papio anubis 99.08 0.00e+00 677.00
IUUC-Psi-093180 Pelodiscus sinensis 93.73 2.00e-156 544.00
IUUC-Pma-094705 Petromyzon marinus 83.13 1.00e-169 588.00
IUUC-Pno-095001 Phaeosphaeria nodorum 41.88 2.00e-62 232.00
IUUC-Ppa-095628 Physcomitrella patens 48.25 2.00e-83 302.00
IUUC-Pfo-097128 Poecilia formosa 91.72 0.00e+00 644.00
IUUC-Pab-098386 Pongo abelii 99.39 0.00e+00 679.00
IUUC-Pop-099064 Populus trichocarpa 47.94 1.00e-81 296.00
IUUC-Pca-100971 Procavia capensis 97.92 5.00e-171 593.00
IUUC-Ppe-101871 Prunus persica 47.94 2.00e-81 295.00
IUUC-Pva-102230 Pteropus vampyrus 78.57 4.00e-132 464.00
IUUC-Pgr-103511 Puccinia graminis 40.82 2.00e-64 239.00
IUUC-Ptt-103882 Puccinia triticina 37.85 3.00e-62 231.00
IUUC-Pte-104402 Pyrenophora teres 44.98 1.00e-73 270.00
IUUC-Pyt-104448 Pyrenophora triticirepentis 44.98 1.00e-73 270.00
IUUC-Rno-104880 Rattus norvegicus 98.16 0.00e+00 673.00
IUUC-Sce-106266 Saccharomyces cerevisiae 47.76 4.00e-84 304.00
IUUC-Sha-106966 Sarcophilus harrisii 95.09 0.00e+00 656.00
IUUC-Sja-107797 Schizosaccharomyces japonicus 46.95 1.00e-83 302.00
IUUC-Spo-108366 Schizosaccharomyces pombe 45.66 5.00e-83 300.00
IUUC-Smo-108749 Selaginella moellendorffii 47.15 3.00e-78 285.00
IUUC-Sit-110741 Setaria italica 49.21 4.00e-83 301.00
IUUC-Sly-111879 Solanum lycopersicum 42.44 3.00e-49 187.00
IUUC-Sbi-114551 Sorghum bicolor 49.21 3.00e-83 301.00
IUUC-Sre-114962 Sporisorium reilianum 39.39 3.00e-72 265.00
IUUC-Ssc-115363 Sus scrofa 98.78 0.00e+00 675.00
IUUC-Tgu-116695 Taeniopygia guttata 77.30 8.00e-143 499.00
IUUC-Tru-117999 Takifugu rubripes 90.24 0.00e+00 634.00
IUUC-Tni-119973 Tetraodon nigroviridis 90.80 0.00e+00 640.00
IUUC-Tca-121688 Theobroma cacao 47.47 9.00e-81 293.00
IUUC-Tre-122158 Trichoderma reesei 42.86 1.00e-74 273.00
IUUC-Tvi-122511 Trichoderma virens 45.14 2.00e-76 278.00
IUUC-Tae-124124 Triticum aestivum 49.52 4.00e-84 304.00
IUUC-Tur-126228 Triticum urartu 46.98 4.00e-76 278.00
IUUC-Tme-127100 Tuber melanosporum 48.23 1.00e-85 309.00
IUUC-Ttr-128216 Tursiops truncatus 98.97 3.00e-54 204.00
IUUC-Uma-129358 Ustilago maydis 40.62 9.00e-74 270.00
IUUC-Vda-129756 Verticillium dahliae 45.40 4.00e-78 284.00
IUUC-Vvi-131581 Vitis vinifera 46.35 2.00e-78 285.00
IUUC-Xtr-132363 Xenopus tropicalis 90.49 0.00e+00 630.00
IUUC-Xma-133857 Xiphophorus maculatus 91.72 0.00e+00 644.00
IUUC-Yli-134368 Yarrowia lipolytica 45.83 1.00e-79 289.00
IUUC-Zma-135854 Zea mays 49.21 2.00e-83 301.00
Created Date 25-Jun-2017

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