iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020483

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03013589

Gene Name

PIK3R4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000006049.3	ENSCAFT00000009780.3	ENSCAFP00000009079.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-17	62.9	992	1021

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H++ v+ ++  ++  l++++s+Dgt+k+W+
   Q: 992  HKSAVNRIRVsDEhSLFATCSNDGTVKIWN 1021
           9999999999544788*************9 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MGNQLAGIAP SQILSVESYF SDIHDFEYDK SLGSTRFFKV ARAKHREGLV VVKVFAIQDP 60
TLPLTSYKQE LEELKIRLHS AQNCLPFQKA VEKASEKAAM LFRQYVRDNL YDRISTRPFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGAAGTGA GGTCAGAGCC GGCAGCTTTC CCGGGAGTTC GGCGTTCTCG GTGTCTGCAT 60
CAGCCGAAGA AGTGGTTTTC CTGGCGCTGG CCGCCTCCGG CTCCGTCCCG CGCCCCGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021133--HEAT_type_2
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50077--HEAT_REPEAT
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00069--Pkinase
PF00400--WD40

SMART

SM00220--S_TKc
SM00320--WD40

Gene Ontology

GO:0005930--C:axoneme
GO:0005770--C:late endosome
GO:0015630--C:microtubule cytoskeleton
GO:0005643--C:nuclear pore
GO:0071561--C:nucleus-vacuole junction
GO:0034271--C:phosphatidylinositol 3-kinase complex, class III, type I
GO:0034272--C:phosphatidylinositol 3-kinase complex, class III, type II
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0042149--P:cellular response to glucose starvation
GO:0045324--P:late endosome to vacuole transport
GO:0016236--P:macroautophagy
GO:0030242--P:pexophagy
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0006468--P:protein phosphorylation
GO:0006623--P:protein targeting to vacuole
GO:0032801--P:receptor catabolic process
GO:0032465--P:regulation of cytokinesis

KEGG

cfa:477064

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000213	Aegilops tauschii	31.87	6.00e-44	173.00
IUUC-Aml-001659	Ailuropoda melanoleuca	99.04	0.00e+00	2734.00
IUUC-Atr-002968	Amborella trichopoda	46.80	7.00e-48	186.00
IUUC-Apl-003418	Anas platyrhynchos	91.79	0.00e+00	2568.00
IUUC-Aca-004344	Anolis carolinensis	90.96	0.00e+00	2294.00
IUUC-Aly-006107	Arabidopsis lyrata	46.97	2.00e-71	265.00
IUUC-Ath-007260	Arabidopsis thaliana	47.27	4.00e-72	267.00
IUUC-Ago-007721	Ashbya gossypii	39.37	6.00e-58	219.00
IUUC-Acl-008378	Aspergillus clavatus	37.20	2.00e-149	523.00
IUUC-Afl-008632	Aspergillus flavus	35.97	6.00e-143	502.00
IUUC-Afu-009020	Aspergillus fumigatus	36.22	4.00e-143	503.00
IUUC-Ani-009204	Aspergillus nidulans	35.63	3.00e-133	470.00
IUUC-Ang-009811	Aspergillus niger	35.30	6.00e-141	495.00
IUUC-Aor-010168	Aspergillus oryzae	35.97	6.00e-143	502.00
IUUC-Ate-010556	Aspergillus terreus	35.26	6.00e-141	495.00
IUUC-Ame-011955	Astyanax mexicanus	81.56	0.00e+00	1817.00
IUUC-Bgr-012050	Blumeria graminis	36.65	1.00e-141	498.00
IUUC-Bta-012432	Bos taurus	96.83	0.00e+00	2693.00
IUUC-Bci-013846	Botrytis cinerea	34.82	6.00e-144	506.00
IUUC-Bdi-015072	Brachypodium distachyon	43.55	2.00e-67	251.00
IUUC-Bol-015314	Brassica oleracea	47.58	4.00e-72	267.00
IUUC-Bra-017476	Brassica rapa	47.58	5.00e-72	266.00
IUUC-Cel-018550	Caenorhabditis elegans	31.98	5.00e-86	313.00
IUUC-Cja-019538	Callithrix jacchus	97.13	0.00e+00	2699.00
IUUC-Cpo-021392	Cavia porcellus	96.69	0.00e+00	2680.00
IUUC-Csa-024112	Chlorocebus sabaeus	97.79	0.00e+00	2709.00
IUUC-Cho-025015	Choloepus hoffmanni	90.34	0.00e+00	947.00
IUUC-Cin-025209	Ciona intestinalis	41.80	0.00e+00	1080.00
IUUC-Csv-026334	Ciona savignyi	41.86	0.00e+00	894.00
IUUC-Cgl-026447	Colletotrichum gloeosporioides	36.03	6.00e-145	509.00
IUUC-Cne-026999	Cryptococcus neoformans	39.75	4.00e-117	416.00
IUUC-Dre-028662	Danio rerio	81.73	0.00e+00	2286.00
IUUC-Dno-029545	Dasypus novemcinctus	95.43	0.00e+00	2630.00
IUUC-Dor-030941	Dipodomys ordii	66.44	0.00e+00	719.00
IUUC-Dse-031455	Dothistroma septosporum	36.53	2.00e-138	487.00
IUUC-Dme-031726	Drosophila melanogaster	48.09	0.00e+00	756.00
IUUC-Ete-033147	Echinops telfairi	94.31	0.00e+00	1008.00
IUUC-Eca-034025	Equus caballus	98.23	0.00e+00	2716.00
IUUC-Eeu-034480	Erinaceus europaeus	90.40	0.00e+00	1525.00
IUUC-Fca-035741	Felis catus	98.23	0.00e+00	2712.00
IUUC-Fal-037666	Ficedula albicollis	90.76	0.00e+00	2544.00
IUUC-Fox-037818	Fusarium oxysporum	33.87	1.00e-127	451.00
IUUC-Fso-038086	Fusarium solani	34.26	1.00e-130	461.00
IUUC-Gmo-038804	Gadus morhua	81.18	0.00e+00	716.00
IUUC-Ggr-039800	Gaeumannomyces graminis	35.83	2.00e-135	477.00
IUUC-Gga-041251	Gallus gallus	90.84	0.00e+00	2000.00
IUUC-Gac-042376	Gasterosteus aculeatus	79.32	0.00e+00	2215.00
IUUC-Gma-044095	Glycine max	46.13	8.00e-74	273.00
IUUC-Ggo-044506	Gorilla gorilla	97.20	0.00e+00	2693.00
IUUC-Hsa-045871	Homo sapiens	97.79	0.00e+00	2705.00
IUUC-Hvu-047648	Hordeum vulgare	30.99	3.00e-45	177.00
IUUC-Itr-048082	Ictidomys tridecemlineatus	98.67	0.00e+00	1211.00
IUUC-Kpa-049390	Komagataella pastoris	32.80	2.00e-128	454.00
IUUC-Lch-050284	Latimeria chalumnae	85.88	0.00e+00	2329.00
IUUC-Lpe-050880	Leersia perrieri	42.05	3.00e-65	244.00
IUUC-Loc-052815	Lepisosteus oculatus	82.26	0.00e+00	2296.00
IUUC-Lma-053324	Leptosphaeria maculans	36.49	7.00e-148	519.00
IUUC-Laf-054204	Loxodonta africana	85.66	0.00e+00	2283.00
IUUC-Mcc-054612	Macaca mulatta	97.79	0.00e+00	2707.00
IUUC-Meu-056227	Macropus eugenii	86.69	0.00e+00	857.00
IUUC-Mor-057094	Magnaporthe oryzae	36.62	3.00e-137	483.00
IUUC-Mtr-058550	Medicago truncatula	44.20	5.00e-73	270.00
IUUC-Mla-058893	Melampsora laricipopulina	35.16	2.00e-132	467.00
IUUC-Mga-059474	Meleagris gallopavo	91.06	0.00e+00	2421.00
IUUC-Mvi-060227	Microbotryum violaceum	45.58	6.00e-86	313.00
IUUC-Mmr-061543	Microcebus murinus	89.84	0.00e+00	2409.00
IUUC-Mdo-062129	Monodelphis domestica	93.44	0.00e+00	2533.00
IUUC-Mmu-064381	Mus musculus	94.99	0.00e+00	2643.00
IUUC-Mac-064455	Musa acuminata	38.55	6.00e-125	442.00
IUUC-Mpu-066151	Mustela putorius furo	99.79	0.00e+00	1000.00
IUUC-Mlu-067824	Myotis lucifugus	97.86	0.00e+00	2707.00
IUUC-Nfi-068241	Neosartorya fischeri	37.54	7.00e-146	512.00
IUUC-Ncr-068964	Neurospora crassa	36.32	9.00e-142	498.00
IUUC-Nle-069152	Nomascus leucogenys	97.86	0.00e+00	2709.00
IUUC-Opr-070870	Ochotona princeps	85.78	0.00e+00	1452.00
IUUC-Ont-071293	Oreochromis niloticus	80.77	0.00e+00	2262.00
IUUC-Oan-072852	Ornithorhynchus anatinus	87.84	0.00e+00	2424.00
IUUC-Ocu-074727	Oryctolagus cuniculus	97.42	0.00e+00	2680.00
IUUC-Oba-075932	Oryza barthii	39.95	5.00e-65	243.00
IUUC-Obr-076424	Oryza brachyantha	47.00	3.00e-62	234.00
IUUC-Ogl-077491	Oryza glaberrima	39.95	5.00e-65	243.00
IUUC-Ogu-078933	Oryza glumaepatula	35.84	1.00e-112	401.00
IUUC-Oin-079604	Oryza indica	44.41	1.00e-70	261.00
IUUC-Olo-080850	Oryza longistaminata	36.19	2.00e-117	417.00
IUUC-Ome-081860	Oryza meridionalis	44.41	2.00e-70	261.00
IUUC-Oni-082895	Oryza nivara	39.95	9.00e-65	242.00
IUUC-Opu-083741	Oryza punctata	44.13	4.00e-69	257.00
IUUC-Oru-084616	Oryza rufipogon	39.64	2.00e-64	241.00
IUUC-Osa-085941	Oryza sativa	28.30	3.00e-34	139.00
IUUC-Ola-087357	Oryzias latipes	86.22	3.00e-160	557.00
IUUC-Olu-087659	Ostreococcus lucimarinus	30.73	3.00e-89	323.00
IUUC-Oga-088555	Otolemur garnettii	97.64	0.00e+00	2684.00
IUUC-Oar-089304	Ovis aries	95.24	0.00e+00	1332.00
IUUC-Ptr-091140	Pan troglodytes	97.86	0.00e+00	2709.00
IUUC-Pan-092413	Papio anubis	97.49	0.00e+00	2598.00
IUUC-Psi-093210	Pelodiscus sinensis	91.55	0.00e+00	2572.00
IUUC-Pma-094674	Petromyzon marinus	57.01	0.00e+00	721.00
IUUC-Pno-094969	Phaeosphaeria nodorum	31.00	8.00e-146	512.00
IUUC-Ppa-096017	Physcomitrella patens	46.42	1.00e-77	285.00
IUUC-Pfo-096077	Poecilia formosa	80.41	0.00e+00	2215.00
IUUC-Pab-098269	Pongo abelii	96.83	0.00e+00	2687.00
IUUC-Pop-100052	Populus trichocarpa	44.47	5.00e-65	243.00
IUUC-Pca-100377	Procavia capensis	92.25	0.00e+00	2441.00
IUUC-Ppe-101445	Prunus persica	46.99	2.00e-73	271.00
IUUC-Pva-102198	Pteropus vampyrus	98.68	0.00e+00	1816.00
IUUC-Pgr-103544	Puccinia graminis	48.11	1.00e-82	302.00
IUUC-Ptt-103964	Puccinia triticina	47.80	1.00e-79	292.00
IUUC-Pte-104196	Pyrenophora teres	37.15	6.00e-140	492.00
IUUC-Pyt-104544	Pyrenophora triticirepentis	37.50	3.00e-138	486.00
IUUC-Rno-105256	Rattus norvegicus	94.99	0.00e+00	2640.00
IUUC-Sce-106295	Saccharomyces cerevisiae	33.37	2.00e-115	411.00
IUUC-Sha-107597	Sarcophilus harrisii	92.66	0.00e+00	2563.00
IUUC-Sja-107781	Schizosaccharomyces japonicus	42.47	6.00e-73	270.00
IUUC-Spo-108031	Schizosaccharomyces pombe	44.14	6.00e-74	273.00
IUUC-Ssl-108579	Sclerotinia sclerotiorum	35.64	1.00e-137	484.00
IUUC-Smo-108679	Selaginella moellendorffii	44.29	3.00e-79	291.00
IUUC-Sit-110765	Setaria italica	42.12	1.00e-64	242.00
IUUC-Sly-111527	Solanum lycopersicum	44.48	3.00e-74	274.00
IUUC-Stu-112899	Solanum tuberosum	44.48	1.00e-74	275.00
IUUC-Sar-112986	Sorex araneus	97.05	0.00e+00	2680.00
IUUC-Sbi-114604	Sorghum bicolor	41.55	1.00e-67	251.00
IUUC-Sre-115191	Sporisorium reilianum	44.31	2.00e-67	252.00
IUUC-Ssc-115440	Sus scrofa	96.17	0.00e+00	2660.00
IUUC-Tgu-116633	Taeniopygia guttata	90.90	0.00e+00	2548.00
IUUC-Tru-118439	Takifugu rubripes	79.02	0.00e+00	2228.00
IUUC-Tsy-119472	Tarsius syrichta	90.68	0.00e+00	1437.00
IUUC-Tni-119808	Tetraodon nigroviridis	74.95	0.00e+00	2026.00
IUUC-Tca-121648	Theobroma cacao	47.89	5.00e-75	276.00
IUUC-Tre-122161	Trichoderma reesei	34.12	1.00e-124	441.00
IUUC-Tvi-122575	Trichoderma virens	33.07	3.00e-116	413.00
IUUC-Tae-123381	Triticum aestivum	47.27	9.00e-68	252.00
IUUC-Tur-126291	Triticum urartu	44.70	2.00e-68	255.00
IUUC-Tme-126979	Tuber melanosporum	37.46	2.00e-151	530.00
IUUC-Tbe-127576	Tupaia belangeri	81.22	0.00e+00	935.00
IUUC-Ttr-129106	Tursiops truncatus	98.94	0.00e+00	1326.00
IUUC-Uma-129633	Ustilago maydis	43.17	7.00e-76	280.00
IUUC-Vda-130001	Verticillium dahliae	34.89	4.00e-131	463.00
IUUC-Vpa-130733	Vicugna pacos	90.57	0.00e+00	1328.00
IUUC-Vvi-131318	Vitis vinifera	44.89	2.00e-72	268.00
IUUC-Xtr-131908	Xenopus tropicalis	86.15	0.00e+00	2435.00
IUUC-Xma-133331	Xiphophorus maculatus	80.41	0.00e+00	2225.00
IUUC-Yli-134651	Yarrowia lipolytica	37.21	6.00e-123	436.00
IUUC-Zma-135850	Zea mays	41.29	2.00e-68	254.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence