iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073534

UUCD1 version

UUC-OrA-00424

Ensembl Protein ID

ENSOANP00000003619.2

UniProt Accession

F7BCJ6; F7BCJ6_ORNAN

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000002285.3	ENSOANT00000003620.3	ENSOANP00000003619.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	1.10e-89	302.1	965	1483

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 69   ynreWekfreqlkvlrkifayldrtyvkkskkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslve 155
             + W+ freql++  ++f      y+++           +++w++++ +d ++rll+l  +l++a+ +++a+++r+l++ ++    
   Q: 965  KPTLWPLFREQLCRRSRLF------YAVR-----------AQAWSRDVTQD-RTRLLRLFPRLNRALGHEQAFADRFLPDEEAG--- 1030
           5678***************......****...........***********.*****************************999... PP
   S: 156  LslnklaiykesFEakfleatqefykaesaeflqe.nevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesll. 240
                la+++++ Ea+  + ++ ++++  + ++   + +d Yl ++e++ +   + aa +++++++++Ll++ve+ +   h      
   Q: 1031 -----LALSRTCREALITPLVHSITRPGPDGLSPLaWLLDLYLDHREEARRARGRSAALASRVRRLSHLLVHVEPSESH-HPPPRDr 1111
           .....89*********************************************************************988.4333331 PP
   S: 241  .aelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnn.dakF 325
             + +  lr++++   ++     +   n+l+ l++++  +++eq++++l+ ++k+ d   +V+r++  +++lq +  e+F+  +a F
   Q: 1112 gGGGDINLRQSRQPGPGLR---PEPQGNSLRDLTRCWMGVVQEQVSRFLAVAWKAPD---FVPRFCGAFQRLQTAGTELFGAcQAGF 1192
           2222222333333333322...445556*****************************...********************974778* PP
   S: 326  lkaldkafetfvnknsvlkaakspEllAryiDqlLrksskglteeeleaqldkvllvfkyisekdv...FekyYkkhLakRLlsgks 409
           + al+++f++++ + ++l+a++++E++A yiD+l++++  ++ ++e ++ql++ l+ f ++s++++   Fe++Y+ +L +RLl    
   Q: 1193 VLALRQGFAAALQQLPFLTASHVSEQFAHYIDELIQAG--RVGSAESLEQLQQSLEPFLVLSGLELatsFEHFYRYYLGERLLG--P 1275
           ************************************99..9999****************************************..9 PP
   S: 410  asseaEesviekLkeecgaeftskL.erMfqdlkvSedlnrqFk.................................eekenteese 462
              ++Ee+v+ ++    g++f+++L ++M+  l +  +l+r+F+                                   k  +e++ 
   Q: 1276 GPCWLEEAVLDQI----GLCFPNRLpQQMLSGLRAAAELQRHFRlfrlqqfdrrllergqeegdgddgedwgpeaepPGKPIQEQQS 1358
           9************....********************************************************99986677788899 PP
   S: 463  svelsvlvLsagaWpta..set..ekvsLPaelektiekfeefY........lekhsgRkLqWqhtlgraelkaelkkgkyelqVst 537
           s+e+ vlvLs+++Wp++  + +  ++  LP+ l+ ++ +f+ fY         e ++ R+LqW++ lg+ael +     ++ l Vst
   Q: 1359 SPEMRVLVLSPRCWPVSplCYMhePSKYLPQALSGYLGRFSDFYshgqsqpgPESGPRRRLQWTW-LGWAELVF---GAQQRLLVST 1441
           *****************997777799**********************9999999**********.********...4499****** PP
   S: 538  fQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvssk 579
           +Qm++LL+fn+ ++v+ve+l ++++l  e+L+++l++L+ss 
   Q: 1442 LQMWILLHFNEAQEVTVETLLQSSGLALELLTQALGPLTSSP 1483
           ***************************************975 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

LISELVRGMG WDLRPGQPDA PLYGFQPHVA FGPDLIPPTP APVPHRRQGR TFRSPSDFSS 60
CSGYAEYVQE TLRPGMRVRM MEDYVVVGAG DEGEFQQSND SVPPAQVLWL ETGRTYCVHW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTCGCTCA CACACACCCT GATATCCGAG CTGGTGCGGG GCATGGGCTG GGACTTGAGG 60
CCGGGCCAGC CGGACGCCCC CCTCTACGGC TTCCAGCCCC ACGTGGCCTT CGGCCCGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR004939--APC_su10/DOC_dom
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR016150--Casein_kin_II_reg-sub_b-sht
IPR021097--CPH_domain
IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR008979--Galactose-bd-like
IPR002867--IBR_dom
IPR014722--Rib_L2_dom2
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
PS51284--DOC

Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00888--Cullin
PF10557--Cullin_Nedd8
PF01485--IBR

SMART

SM01337--APC10
SM00884--Cullin_Nedd8
SM00647--IBR

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0046872--F:metal ion binding
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001405	Ailuropoda melanoleuca	58.26	0.00e+00	2161.00
IUUC-Apl-003458	Anas platyrhynchos	64.79	0.00e+00	704.00
IUUC-Aca-004815	Anolis carolinensis	51.59	0.00e+00	1949.00
IUUC-Ame-010611	Astyanax mexicanus	46.87	0.00e+00	1773.00
IUUC-Bta-012877	Bos taurus	58.83	0.00e+00	2107.00
IUUC-Cja-019255	Callithrix jacchus	58.47	0.00e+00	2159.00
IUUC-Cfa-020119	Canis familiaris	58.63	0.00e+00	2149.00
IUUC-Cpo-022473	Cavia porcellus	57.00	0.00e+00	2009.00
IUUC-Csa-024157	Chlorocebus sabaeus	58.93	0.00e+00	2168.00
IUUC-Cho-024879	Choloepus hoffmanni	58.14	4.00e-149	523.00
IUUC-Cin-025402	Ciona intestinalis	30.86	0.00e+00	662.00
IUUC-Dno-028904	Dasypus novemcinctus	59.27	0.00e+00	2169.00
IUUC-Dor-030112	Dipodomys ordii	60.42	0.00e+00	889.00
IUUC-Ete-032516	Echinops telfairi	52.59	0.00e+00	662.00
IUUC-Eca-034394	Equus caballus	58.22	0.00e+00	2083.00
IUUC-Eeu-035166	Erinaceus europaeus	66.29	0.00e+00	1561.00
IUUC-Fca-035740	Felis catus	59.44	0.00e+00	2175.00
IUUC-Fal-036672	Ficedula albicollis	48.03	0.00e+00	1055.00
IUUC-Gga-040154	Gallus gallus	57.65	0.00e+00	843.00
IUUC-Ggo-045570	Gorilla gorilla	58.10	0.00e+00	2147.00
IUUC-Hsa-046690	Homo sapiens	58.71	0.00e+00	2159.00
IUUC-Itr-048680	Ictidomys tridecemlineatus	58.33	0.00e+00	2196.00
IUUC-Loc-052706	Lepisosteus oculatus	48.95	0.00e+00	1823.00
IUUC-Mcc-055727	Macaca mulatta	58.79	0.00e+00	2187.00
IUUC-Meu-056074	Macropus eugenii	67.08	0.00e+00	1282.00
IUUC-Mmr-060869	Microcebus murinus	58.34	0.00e+00	2118.00
IUUC-Mdo-062902	Monodelphis domestica	63.45	0.00e+00	2304.00
IUUC-Mmu-063991	Mus musculus	57.12	0.00e+00	2055.00
IUUC-Mpu-065974	Mustela putorius furo	58.01	0.00e+00	2139.00
IUUC-Nle-069292	Nomascus leucogenys	65.53	0.00e+00	1760.00
IUUC-Opr-071020	Ochotona princeps	57.40	0.00e+00	1297.00
IUUC-Ont-071953	Oreochromis niloticus	47.39	0.00e+00	1674.00
IUUC-Ocu-074244	Oryctolagus cuniculus	57.53	0.00e+00	2137.00
IUUC-Ola-087072	Oryzias latipes	51.24	0.00e+00	1605.00
IUUC-Oga-088310	Otolemur garnettii	56.09	0.00e+00	2056.00
IUUC-Oar-090174	Ovis aries	57.37	0.00e+00	2080.00
IUUC-Ptr-091410	Pan troglodytes	58.29	0.00e+00	2135.00
IUUC-Pan-091856	Papio anubis	53.73	0.00e+00	1110.00
IUUC-Pma-094192	Petromyzon marinus	46.15	0.00e+00	1215.00
IUUC-Pfo-096773	Poecilia formosa	55.24	0.00e+00	930.00
IUUC-Pab-098635	Pongo abelii	63.12	0.00e+00	1827.00
IUUC-Pca-100539	Procavia capensis	64.56	0.00e+00	934.00
IUUC-Pva-102813	Pteropus vampyrus	63.74	0.00e+00	1090.00
IUUC-Rno-106105	Rattus norvegicus	57.01	0.00e+00	2086.00
IUUC-Sha-106896	Sarcophilus harrisii	70.55	0.00e+00	1002.00
IUUC-Ssl-108406	Sclerotinia sclerotiorum	26.49	3.00e-08	52.40
IUUC-Sar-113132	Sorex araneus	68.12	0.00e+00	720.00
IUUC-Ssc-116000	Sus scrofa	58.76	0.00e+00	2106.00
IUUC-Tru-118013	Takifugu rubripes	53.32	0.00e+00	1441.00
IUUC-Tsy-119037	Tarsius syrichta	53.40	2.00e-101	364.00
IUUC-Tni-120062	Tetraodon nigroviridis	55.69	0.00e+00	1493.00
IUUC-Ttr-128780	Tursiops truncatus	58.99	0.00e+00	961.00
IUUC-Vpa-130086	Vicugna pacos	54.00	0.00e+00	780.00
IUUC-Xtr-132882	Xenopus tropicalis	48.24	0.00e+00	1669.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence