iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055137

UUCD1 version

UUC-MaM-00218

Ensembl Protein ID

ENSMMUP00000021997.3

UniProt Accession

F6V5Y8; F6V612; F6V5Y8_MACMU

Genbank Protein ID

AFE65030.1; AFH29844.1; AFI36845.1; EHH15124.1

Protein Name

E3 ubiquitin-protein ligase RNF115

Genbank Nucleotide ID

JSUE03002338; JU473040; JV046774; CM001253

Gene Name

RNF115; EGK_01173

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000016736.3	ENSMMUT00000023512.3	ENSMMUP00000021997.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.50e-09	37.8	228	269

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+ed+  +++++ lpC+H+fh +C+  w         +++CP+Cr
   Q: 228  CPVCKEDYtvEEEVRQLPCNHFFHSSCIVPW------LELHDTCPVCR 269
           ********99777******************......**********8 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAEASAAGAD SGAAVAAHRF FCHFCKGEVS PKLPEYICPR CESGFIEEVT DDSSFLGGGG 60
SRIDNSTTTH FAELWGHLDH TMFFQDFRPF LSGNPLDQDN RANERGHQTH TDFWGARPPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCTACTGCA GCCCGGGAGG TAGCGGCCTG GCGAGGGACG GGCCGGCTGC CTTCTCGGAC 60
GGCCGCGGCG GAGGACAAAA ATGGCGGAGG CTTCGGCGGC CGGGGCGGAC TCGGGCGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

KEGG

mcc:697067

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000079	Aegilops tauschii	30.74	4.00e-24	105.00
IUUC-Aml-002035	Ailuropoda melanoleuca	94.44	3.00e-146	510.00
IUUC-Apl-003694	Anas platyrhynchos	89.16	2.00e-77	281.00
IUUC-Aca-004365	Anolis carolinensis	77.06	7.00e-42	162.00
IUUC-Acl-008247	Aspergillus clavatus	36.11	5.00e-19	89.00
IUUC-Ate-010398	Aspergillus terreus	38.66	1.00e-18	87.80
IUUC-Ame-011898	Astyanax mexicanus	53.60	7.00e-71	260.00
IUUC-Bta-013190	Bos taurus	81.94	3.00e-117	414.00
IUUC-Bci-013958	Botrytis cinerea	37.14	2.00e-17	84.30
IUUC-Bol-016085	Brassica oleracea	41.18	1.00e-26	114.00
IUUC-Bra-016939	Brassica rapa	31.43	2.00e-26	112.00
IUUC-Cja-020001	Callithrix jacchus	95.47	1.00e-149	521.00
IUUC-Cfa-020882	Canis familiaris	94.43	2.00e-145	508.00
IUUC-Cpo-021690	Cavia porcellus	80.94	1.00e-113	402.00
IUUC-Csa-024004	Chlorocebus sabaeus	100.00	2.00e-149	521.00
IUUC-Cho-024643	Choloepus hoffmanni	93.17	6.00e-78	283.00
IUUC-Cin-025452	Ciona intestinalis	44.32	2.00e-18	84.70
IUUC-Csv-025892	Ciona savignyi	43.68	2.00e-20	91.30
IUUC-Dre-027515	Danio rerio	58.68	2.00e-80	291.00
IUUC-Dno-029010	Dasypus novemcinctus	93.75	2.00e-145	508.00
IUUC-Dor-030147	Dipodomys ordii	85.24	2.00e-123	434.00
IUUC-Dse-031376	Dothistroma septosporum	37.07	4.00e-17	82.80
IUUC-Dme-031601	Drosophila melanogaster	54.55	1.00e-34	140.00
IUUC-Ete-032392	Echinops telfairi	90.68	3.00e-76	278.00
IUUC-Eca-033803	Equus caballus	93.36	2.00e-133	468.00
IUUC-Eeu-034831	Erinaceus europaeus	75.43	2.00e-95	342.00
IUUC-Fca-036192	Felis catus	93.40	1.00e-150	525.00
IUUC-Gmo-039513	Gadus morhua	59.12	3.00e-87	314.00
IUUC-Gga-040282	Gallus gallus	79.41	1.00e-74	271.00
IUUC-Gac-041784	Gasterosteus aculeatus	59.12	6.00e-86	310.00
IUUC-Ggo-044873	Gorilla gorilla	98.61	2.00e-148	517.00
IUUC-Hsa-045780	Homo sapiens	98.61	4.00e-148	516.00
IUUC-Hvu-047602	Hordeum vulgare	29.34	2.00e-24	106.00
IUUC-Itr-048142	Ictidomys tridecemlineatus	92.62	1.00e-133	468.00
IUUC-Lch-050673	Latimeria chalumnae	76.12	6.00e-120	423.00
IUUC-Laf-054384	Loxodonta africana	88.19	8.00e-135	473.00
IUUC-Meu-056635	Macropus eugenii	85.98	2.00e-110	392.00
IUUC-Mtr-058295	Medicago truncatula	30.98	3.00e-23	102.00
IUUC-Mla-058832	Melampsora laricipopulina	46.84	1.00e-14	72.40
IUUC-Mmr-060631	Microcebus murinus	95.49	1.00e-153	535.00
IUUC-Mdo-062489	Monodelphis domestica	87.50	7.00e-125	439.00
IUUC-Mmu-064196	Mus musculus	93.75	6.00e-151	526.00
IUUC-Mac-065133	Musa acuminata	45.05	3.00e-26	111.00
IUUC-Mpu-066575	Mustela putorius furo	94.44	2.00e-151	528.00
IUUC-Mlu-067024	Myotis lucifugus	87.08	2.00e-131	461.00
IUUC-Nle-069348	Nomascus leucogenys	97.56	3.00e-145	507.00
IUUC-Opr-070812	Ochotona princeps	86.81	8.00e-137	479.00
IUUC-Ont-072238	Oreochromis niloticus	46.84	4.00e-61	228.00
IUUC-Ocu-074691	Oryctolagus cuniculus	95.49	1.00e-144	505.00
IUUC-Oin-079595	Oryza indica	50.00	3.00e-21	97.40
IUUC-Ola-087047	Oryzias latipes	62.07	4.00e-89	320.00
IUUC-Oga-089111	Otolemur garnettii	93.43	8.00e-138	483.00
IUUC-Oar-089999	Ovis aries	81.94	1.00e-117	416.00
IUUC-Ptr-091473	Pan troglodytes	98.61	1.00e-147	515.00
IUUC-Pan-092618	Papio anubis	86.41	5.00e-120	423.00
IUUC-Psi-093930	Pelodiscus sinensis	81.03	8.00e-111	393.00
IUUC-Pma-094530	Petromyzon marinus	47.15	3.00e-58	218.00
IUUC-Pno-094903	Phaeosphaeria nodorum	41.88	7.00e-18	85.10
IUUC-Pfo-096461	Poecilia formosa	69.70	1.00e-63	236.00
IUUC-Pab-098466	Pongo abelii	99.30	6.00e-149	520.00
IUUC-Pca-100550	Procavia capensis	73.61	1.00e-103	369.00
IUUC-Pva-102881	Pteropus vampyrus	90.28	5.00e-140	490.00
IUUC-Rno-104914	Rattus norvegicus	94.10	3.00e-151	527.00
IUUC-Sha-107616	Sarcophilus harrisii	87.45	2.00e-112	398.00
IUUC-Sja-107922	Schizosaccharomyces japonicus	41.04	1.00e-23	104.00
IUUC-Spo-108354	Schizosaccharomyces pombe	37.06	1.00e-24	107.00
IUUC-Smo-109522	Selaginella moellendorffii	51.43	5.00e-20	88.60
IUUC-Sar-113319	Sorex araneus	70.99	2.00e-57	215.00
IUUC-Sre-115230	Sporisorium reilianum	38.79	1.00e-17	84.70
IUUC-Ssc-115917	Sus scrofa	83.33	1.00e-122	432.00
IUUC-Tgu-117105	Taeniopygia guttata	90.48	3.00e-66	243.00
IUUC-Tru-118087	Takifugu rubripes	48.50	2.00e-59	222.00
IUUC-Tsy-119630	Tarsius syrichta	84.56	1.00e-127	449.00
IUUC-Tni-120265	Tetraodon nigroviridis	64.48	3.00e-94	338.00
IUUC-Tae-124758	Triticum aestivum	49.50	1.00e-21	97.10
IUUC-Tur-125986	Triticum urartu	29.96	6.00e-23	102.00
IUUC-Tme-127143	Tuber melanosporum	48.51	2.00e-26	112.00
IUUC-Tbe-127794	Tupaia belangeri	72.11	1.00e-89	322.00
IUUC-Ttr-129117	Tursiops truncatus	81.25	1.00e-114	405.00
IUUC-Uma-129414	Ustilago maydis	36.67	1.00e-17	84.70
IUUC-Vpa-130755	Vicugna pacos	80.44	5.00e-107	380.00
IUUC-Xtr-132520	Xenopus tropicalis	72.99	3.00e-94	338.00
IUUC-Xma-133074	Xiphophorus maculatus	69.70	3.00e-63	235.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence