iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020992

Ensembl Protein ID

ENSCAFP00000011292.4

UniProt Accession

F1Q3X8; F1Q3X8_CANLF

Genbank Protein ID

ENSCAFP00000011292

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03014297

Gene Name

SH3RF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000007608.4	ENSCAFT00000012180.4	ENSCAFP00000011292.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.80e-08	33.2	12	53
UBD/SH3	5.40e-48	161.1	448	502

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Cl  +      s++e rCP Cr
   Q: 12   CPVCLERLDASAKVLPCQHTFCKRCLLGI----VGSRNELRCPECR 53
           **********9**************9777....899*********8 PP

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
             ++y+y++ ++deL+l+kG++ lv  + +   gW kg++  + k G+fP n+v+ +
   Q: 448  YVAIYPYTPRKEDELELRKGEMFLVF-ERC-QDGWFKGTSMHTSKIGVFPGNYVAPV 502
           679**********************9.555.569********************988 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MDESALLDLL ECPVCLERLD ASAKVLPCQH TFCKRCLLGI VGSRNELRCP ECRTLVGSGV 60
EELPSNILLV RLLDGIKQRP WKPGPGGGSG MNCTNALRAQ SSTVANCSSK DLQSSQGGQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCAAAGTCT GAAATGGATG TTACATGAGT CACTTTAAGG GATGCACGGA ACTATGAACA 60
TTTCTGAAGC TTTTTTCTCA GTAAACTAGA TAAAGATGGA TGAATCTGCC TTGTTGGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0046328--P:regulation of JNK cascade

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	94.12	0.00e+00	1415.00
IUUC-Apl-003961	Anas platyrhynchos	79.37	0.00e+00	1200.00
IUUC-Aca-004386	Anolis carolinensis	75.85	0.00e+00	1181.00
IUUC-Ame-010659	Astyanax mexicanus	59.72	0.00e+00	890.00
IUUC-Bta-012563	Bos taurus	67.40	1.00e-131	463.00
IUUC-Cja-019730	Callithrix jacchus	88.31	0.00e+00	1330.00
IUUC-Cpo-021304	Cavia porcellus	89.09	0.00e+00	1441.00
IUUC-Csa-023925	Chlorocebus sabaeus	88.96	0.00e+00	1360.00
IUUC-Cho-024630	Choloepus hoffmanni	82.40	0.00e+00	888.00
IUUC-Cin-025274	Ciona intestinalis	45.79	2.00e-71	261.00
IUUC-Csv-026136	Ciona savignyi	44.08	7.00e-73	267.00
IUUC-Dre-028290	Danio rerio	60.91	0.00e+00	912.00
IUUC-Dno-029083	Dasypus novemcinctus	86.58	0.00e+00	1276.00
IUUC-Dor-030388	Dipodomys ordii	95.51	0.00e+00	691.00
IUUC-Dme-032207	Drosophila melanogaster	45.90	1.00e-63	238.00
IUUC-Ete-032809	Echinops telfairi	77.87	0.00e+00	867.00
IUUC-Eca-034185	Equus caballus	92.21	0.00e+00	1163.00
IUUC-Eeu-034816	Erinaceus europaeus	79.19	0.00e+00	1184.00
IUUC-Fca-036439	Felis catus	91.48	0.00e+00	1467.00
IUUC-Fal-037074	Ficedula albicollis	78.12	0.00e+00	1177.00
IUUC-Gmo-039443	Gadus morhua	60.53	5.00e-120	425.00
IUUC-Gga-040749	Gallus gallus	78.39	0.00e+00	1146.00
IUUC-Gac-041420	Gasterosteus aculeatus	73.84	4.00e-150	525.00
IUUC-Ggo-045215	Gorilla gorilla	90.45	0.00e+00	1393.00
IUUC-Hsa-046315	Homo sapiens	89.56	0.00e+00	1388.00
IUUC-Itr-048265	Ictidomys tridecemlineatus	84.54	2.00e-151	528.00
IUUC-Lch-049453	Latimeria chalumnae	70.05	0.00e+00	904.00
IUUC-Loc-052248	Lepisosteus oculatus	38.54	2.00e-75	277.00
IUUC-Laf-053651	Loxodonta africana	88.51	0.00e+00	1339.00
IUUC-Mcc-054688	Macaca mulatta	89.46	0.00e+00	1387.00
IUUC-Meu-056291	Macropus eugenii	74.19	0.00e+00	793.00
IUUC-Mga-059944	Meleagris gallopavo	77.49	0.00e+00	1178.00
IUUC-Mmr-061553	Microcebus murinus	88.15	0.00e+00	1279.00
IUUC-Mdo-062313	Monodelphis domestica	77.36	0.00e+00	1187.00
IUUC-Mmu-063516	Mus musculus	86.80	0.00e+00	1372.00
IUUC-Mpu-066064	Mustela putorius furo	95.12	0.00e+00	1440.00
IUUC-Mlu-067312	Myotis lucifugus	88.17	0.00e+00	1296.00
IUUC-Nle-069035	Nomascus leucogenys	90.56	0.00e+00	1394.00
IUUC-Opr-070690	Ochotona princeps	84.36	0.00e+00	659.00
IUUC-Ont-071484	Oreochromis niloticus	62.92	0.00e+00	723.00
IUUC-Oan-073305	Ornithorhynchus anatinus	80.29	0.00e+00	1236.00
IUUC-Ocu-074936	Oryctolagus cuniculus	88.62	0.00e+00	1382.00
IUUC-Ola-086675	Oryzias latipes	61.05	2.00e-176	612.00
IUUC-Oga-087933	Otolemur garnettii	80.24	0.00e+00	1027.00
IUUC-Oar-090408	Ovis aries	63.52	2.00e-118	419.00
IUUC-Ptr-090865	Pan troglodytes	89.67	0.00e+00	1390.00
IUUC-Pan-092362	Papio anubis	89.08	0.00e+00	1360.00
IUUC-Psi-093876	Pelodiscus sinensis	78.37	0.00e+00	1201.00
IUUC-Pfo-097116	Poecilia formosa	58.99	0.00e+00	853.00
IUUC-Pab-098127	Pongo abelii	89.90	0.00e+00	1393.00
IUUC-Pca-100485	Procavia capensis	88.60	0.00e+00	1022.00
IUUC-Pva-102661	Pteropus vampyrus	89.15	0.00e+00	1320.00
IUUC-Rno-105728	Rattus norvegicus	87.96	0.00e+00	1364.00
IUUC-Sha-106515	Sarcophilus harrisii	83.42	0.00e+00	860.00
IUUC-Sar-113161	Sorex araneus	96.07	0.00e+00	673.00
IUUC-Ssc-115314	Sus scrofa	78.91	0.00e+00	1110.00
IUUC-Tgu-117012	Taeniopygia guttata	78.80	0.00e+00	1184.00
IUUC-Tru-118467	Takifugu rubripes	59.76	2.00e-161	563.00
IUUC-Tsy-119566	Tarsius syrichta	83.45	2.00e-177	616.00
IUUC-Tni-120830	Tetraodon nigroviridis	63.81	1.00e-116	414.00
IUUC-Tbe-128070	Tupaia belangeri	86.13	0.00e+00	902.00
IUUC-Ttr-128161	Tursiops truncatus	94.51	8.00e-143	501.00
IUUC-Xtr-132628	Xenopus tropicalis	72.22	0.00e+00	1085.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence