iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089881

Ensembl Protein ID

ENSOARP00000022553.1

UniProt Accession

W5QIK1; W5QIK1_SHEEP

Genbank Protein ID

ENSOARP00000022553

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01103599

Gene Name

USP50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000020986.1	ENSOART00000022864.1	ENSOARP00000022553.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.90e-84	283.3	49	365

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           tGl+NlgNtCYmN++LQcL +i++l e++l+ k+ ++l+     +   e++++++ +++ +w  +   vsp+ l +al+++ + f +  
   Q: 49   TGLRNLGNTCYMNAILQCLCSISPLVEYFLSgKYINALQ-----KGCSEVATAFAYVMTDMWLADCDCVSPEILRSALGNLYPVFMKKT 132
           7******************************44444444.....45679**************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           qqDaqEfl ++l++l+e+l     k++++ ++ +k++ ++   +k    ++s+i++lF+gql+ +i+cl+c+n + ++e f+ +slp+p
   Q: 133  QQDAQEFLIYVLNELHEAL-----KKYHRRKSYEKRSIPRY-CRKMIANESSIITRLFEGQLSYSIVCLKCENCTYKNEVFTIISLPIP 215
           *******************.....45666666666666666.578888999************************************** PP
   S: 178  gkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfc 265
           +k e+   slqdcL+ f+++++l+ +n+++c+ c+ kqe+  + +++k P+++++hLkRf  +  + +++k+ + +++pl+ Ldl+p+ 
   Q: 216  SKYEC---SLQDCLQCFFQQDTLTWNNQIHCSFCETKQETAVRATISKAPKTIVFHLKRF--DILGTMKRKLRTDIHYPLTnLDLTPYI 299
           *****...****************************************************..55668999******************* PP
   S: 266  tspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           +   +k   + kY+L+avv+H G l++GHY+a+ kn+  + W+ fdD++++e++ + v++   + aY+lfY 
   Q: 300  CPIFRK---HPKYNLCAVVNHFGDLDGGHYTAFSKNSVTQaWYSFDDTRISEIPDTAVQT---AAAYLLFYS 365
           **7765...79*************************98888*******************...********6 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MWFHEMASQR SFPEDDFSIY YVLAEHTDHY DPCPVNEAEE NQPHLQGVTG LRNLGNTCYM 60
NAILQCLCSI SPLVEYFLSG KYINALQKGC SEVATAFAYV MTDMWLADCD CVSPEILRSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGTTTC ATGAAATGGC TTCACAGCGG TCTTTCCCTG AAGATGACTT CAGTATCTAC 60
TATGTCCTGT GAGCTCCCGT CTACTATAGT TTTTTAGATA AGCTTAGTTA CGGTGGTAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination

KEGG

oas:101106690

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002089	Ailuropoda melanoleuca	86.63	0.00e+00	691.00
IUUC-Aca-005256	Anolis carolinensis	48.85	6.00e-100	357.00
IUUC-Bta-012753	Bos taurus	92.59	0.00e+00	725.00
IUUC-Cfa-020054	Canis familiaris	83.83	2.00e-169	588.00
IUUC-Cpo-021375	Cavia porcellus	74.66	1.00e-164	572.00
IUUC-Csa-023902	Chlorocebus sabaeus	80.45	6.00e-102	362.00
IUUC-Cho-024755	Choloepus hoffmanni	73.08	8.00e-143	499.00
IUUC-Dor-030311	Dipodomys ordii	84.86	5.00e-92	330.00
IUUC-Ete-032570	Echinops telfairi	61.99	2.00e-101	361.00
IUUC-Eca-034343	Equus caballus	87.23	0.00e+00	692.00
IUUC-Eeu-034510	Erinaceus europaeus	85.58	2.00e-165	574.00
IUUC-Fca-035920	Felis catus	88.20	0.00e+00	687.00
IUUC-Fal-036903	Ficedula albicollis	53.87	2.00e-102	365.00
IUUC-Gac-042261	Gasterosteus aculeatus	40.24	6.00e-69	254.00
IUUC-Hsa-046665	Homo sapiens	79.88	2.00e-159	554.00
IUUC-Itr-048167	Ictidomys tridecemlineatus	87.17	0.00e+00	696.00
IUUC-Lch-049925	Latimeria chalumnae	53.47	1.00e-104	372.00
IUUC-Loc-051880	Lepisosteus oculatus	47.83	3.00e-79	290.00
IUUC-Laf-054494	Loxodonta africana	85.87	0.00e+00	671.00
IUUC-Mcc-055507	Macaca mulatta	84.86	3.00e-179	620.00
IUUC-Meu-055906	Macropus eugenii	72.67	3.00e-146	510.00
IUUC-Mmr-061564	Microcebus murinus	62.13	1.00e-106	379.00
IUUC-Mdo-061800	Monodelphis domestica	77.26	7.00e-174	603.00
IUUC-Mmu-063618	Mus musculus	80.42	0.00e+00	626.00
IUUC-Mpu-066699	Mustela putorius furo	88.20	0.00e+00	698.00
IUUC-Mlu-067672	Myotis lucifugus	84.22	0.00e+00	668.00
IUUC-Opr-070949	Ochotona princeps	80.51	4.00e-152	530.00
IUUC-Oan-073725	Ornithorhynchus anatinus	64.05	3.00e-140	491.00
IUUC-Ocu-074021	Oryctolagus cuniculus	87.30	0.00e+00	691.00
IUUC-Oga-088258	Otolemur garnettii	86.69	1.00e-168	585.00
IUUC-Ptr-090988	Pan troglodytes	80.30	1.00e-155	541.00
IUUC-Pan-091773	Papio anubis	84.68	0.00e+00	654.00
IUUC-Psi-093243	Pelodiscus sinensis	69.81	5.00e-136	476.00
IUUC-Pab-097713	Pongo abelii	81.02	2.00e-170	591.00
IUUC-Pca-100226	Procavia capensis	67.75	3.00e-132	464.00
IUUC-Pva-103172	Pteropus vampyrus	86.98	4.00e-178	616.00
IUUC-Rno-105950	Rattus norvegicus	82.84	0.00e+00	639.00
IUUC-Sha-107026	Sarcophilus harrisii	76.92	5.00e-166	577.00
IUUC-Ssc-116383	Sus scrofa	90.69	0.00e+00	720.00
IUUC-Tgu-116511	Taeniopygia guttata	53.71	6.00e-97	347.00
IUUC-Tsy-119444	Tarsius syrichta	94.78	2.00e-64	239.00
IUUC-Tbe-127808	Tupaia belangeri	81.02	2.00e-60	226.00
IUUC-Ttr-129046	Tursiops truncatus	86.98	2.00e-175	608.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence