iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089854

Ensembl Protein ID

ENSOARP00000015577.1

UniProt Accession

W5PYP2; W5PYP2_SHEEP

Genbank Protein ID

ENSOARP00000015577

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01025198

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000014521.1	ENSOART00000015807.1	ENSOARP00000015577.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.40e-23	81.4	367	398
UBD/Beta-Prp	2.30e-42	145.4	280	488

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 367  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 398
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 280  KSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 368
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 369  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDS-AINRINVCVGQKIIALPHDNRQVRLFDMsgvRLARLPRSSRQGH 455
           ******99999.********************988874555555.55555555559*****************555555555555777* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v   +++++     l +++ d++ + w++ 
   Q: 456  RRMVCGSAWSEDHpvCNLFTCGFDRQAIGWNIN 488
           ***********99878899*********99986 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MPTESGSCSA ARQAKQKRKS HSLSIRRTNS SEQERTGLPR DMLEGQDSKL PSSVRSTLLE 60
LFGQIEREFE NLYIENLELR REIETLNERL AAEGQAIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATCTTGCAG GAGTGACCAG GACCTCATCT TCCAGAAGTA ATGCCCACAG AAAGCGGGAG 60
TTGTTCAGCT GCTCGCCAAG CAAAACAGAA GCGCAAATCT CACAGCCTTT CCATACGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

KEGG

oas:101112244

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	95.56	0.00e+00	958.00
IUUC-Apl-003647	Anas platyrhynchos	93.35	0.00e+00	935.00
IUUC-Aca-004759	Anolis carolinensis	91.53	0.00e+00	934.00
IUUC-Ame-011103	Astyanax mexicanus	56.35	8.00e-144	503.00
IUUC-Bta-012718	Bos taurus	99.40	0.00e+00	987.00
IUUC-Cel-018499	Caenorhabditis elegans	41.94	2.00e-93	336.00
IUUC-Cja-019492	Callithrix jacchus	95.56	0.00e+00	979.00
IUUC-Cfa-020199	Canis familiaris	95.56	0.00e+00	988.00
IUUC-Cpo-022500	Cavia porcellus	88.91	0.00e+00	922.00
IUUC-Csa-023567	Chlorocebus sabaeus	96.17	0.00e+00	984.00
IUUC-Cho-025071	Choloepus hoffmanni	67.54	0.00e+00	635.00
IUUC-Cin-025460	Ciona intestinalis	45.53	5.00e-104	371.00
IUUC-Csv-026042	Ciona savignyi	46.43	2.00e-107	382.00
IUUC-Dre-028214	Danio rerio	84.07	0.00e+00	857.00
IUUC-Dno-029826	Dasypus novemcinctus	93.49	0.00e+00	807.00
IUUC-Dor-030967	Dipodomys ordii	95.36	0.00e+00	885.00
IUUC-Dme-031936	Drosophila melanogaster	49.58	4.00e-117	414.00
IUUC-Ete-032452	Echinops telfairi	91.33	0.00e+00	931.00
IUUC-Eca-033278	Equus caballus	95.36	0.00e+00	985.00
IUUC-Eeu-034592	Erinaceus europaeus	82.26	0.00e+00	817.00
IUUC-Fca-036431	Felis catus	95.98	0.00e+00	989.00
IUUC-Fal-037149	Ficedula albicollis	91.73	0.00e+00	924.00
IUUC-Gmo-038476	Gadus morhua	78.44	0.00e+00	763.00
IUUC-Gga-041099	Gallus gallus	92.54	0.00e+00	929.00
IUUC-Gac-042374	Gasterosteus aculeatus	84.60	0.00e+00	818.00
IUUC-Ggo-044683	Gorilla gorilla	87.90	0.00e+00	891.00
IUUC-Hsa-046658	Homo sapiens	95.36	0.00e+00	978.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	95.60	0.00e+00	909.00
IUUC-Lch-050571	Latimeria chalumnae	83.68	0.00e+00	870.00
IUUC-Loc-052652	Lepisosteus oculatus	81.30	0.00e+00	848.00
IUUC-Laf-053712	Loxodonta africana	94.19	0.00e+00	965.00
IUUC-Mcc-055521	Macaca mulatta	96.17	0.00e+00	984.00
IUUC-Meu-056324	Macropus eugenii	88.31	0.00e+00	878.00
IUUC-Mga-060114	Meleagris gallopavo	92.74	0.00e+00	936.00
IUUC-Mmr-061176	Microcebus murinus	96.37	0.00e+00	986.00
IUUC-Mdo-061888	Monodelphis domestica	92.94	0.00e+00	919.00
IUUC-Mmu-063977	Mus musculus	94.76	0.00e+00	984.00
IUUC-Mpu-066220	Mustela putorius furo	82.35	1.00e-180	625.00
IUUC-Mlu-068155	Myotis lucifugus	95.56	0.00e+00	986.00
IUUC-Nle-069964	Nomascus leucogenys	95.56	0.00e+00	980.00
IUUC-Opr-070925	Ochotona princeps	92.39	4.00e-146	510.00
IUUC-Ont-071317	Oreochromis niloticus	86.09	0.00e+00	839.00
IUUC-Oan-072952	Ornithorhynchus anatinus	93.35	0.00e+00	944.00
IUUC-Ocu-073913	Oryctolagus cuniculus	95.77	0.00e+00	986.00
IUUC-Ola-087024	Oryzias latipes	84.51	0.00e+00	877.00
IUUC-Oga-087945	Otolemur garnettii	95.77	0.00e+00	986.00
IUUC-Ptr-091486	Pan troglodytes	95.56	0.00e+00	979.00
IUUC-Pan-091738	Papio anubis	96.17	0.00e+00	984.00
IUUC-Psi-093953	Pelodiscus sinensis	92.54	0.00e+00	937.00
IUUC-Pma-094560	Petromyzon marinus	74.65	0.00e+00	771.00
IUUC-Pfo-097222	Poecilia formosa	82.26	0.00e+00	823.00
IUUC-Pab-098778	Pongo abelii	91.33	0.00e+00	920.00
IUUC-Pca-100852	Procavia capensis	90.73	0.00e+00	914.00
IUUC-Pva-103130	Pteropus vampyrus	95.87	5.00e-134	471.00
IUUC-Rno-105848	Rattus norvegicus	85.69	0.00e+00	867.00
IUUC-Sha-106750	Sarcophilus harrisii	93.15	0.00e+00	945.00
IUUC-Sar-113749	Sorex araneus	86.69	0.00e+00	874.00
IUUC-Ssc-115691	Sus scrofa	96.37	0.00e+00	954.00
IUUC-Tgu-117365	Taeniopygia guttata	91.13	0.00e+00	879.00
IUUC-Tru-117595	Takifugu rubripes	83.27	0.00e+00	823.00
IUUC-Tsy-118973	Tarsius syrichta	74.18	2.00e-149	521.00
IUUC-Tni-120545	Tetraodon nigroviridis	82.93	0.00e+00	859.00
IUUC-Tbe-127976	Tupaia belangeri	70.97	0.00e+00	686.00
IUUC-Ttr-128472	Tursiops truncatus	95.56	0.00e+00	971.00
IUUC-Xtr-132621	Xenopus tropicalis	89.72	0.00e+00	888.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence