iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073913

UUCD1 version

UUC-OrC-00173

Ensembl Protein ID

ENSOCUP00000003859.2

UniProt Accession

G1SLV7; G1SLV7_RABIT

Protein Name

Uncharacterized protein

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000004466.2	ENSOCUT00000004468.2	ENSOCUP00000003859.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.20e-24	84.0	367	398
UBD/Beta-Prp	2.30e-45	155.1	280	488

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 367  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 398
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 280  KSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 368
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 369  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDS-AINRINVCVGQKIIALPHDNRQVRLFDMsgvRLARLPRSSRQGH 455
           ******99999.********************988874555555.55555555558*****************555555555555777* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 456  RRMVCCSAWSEDHpiCNLFTCGFDRQAIGWNIN 488
           ************9777899***********986 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MPTESGSCST ARQAKQKRKS HSLSIRRTNS SEQERTGLPR EMLEGQDSKL PSSVRSTLLE 60
LFGQIEREFE NLYIENLELR REIDTLNERL AAEGQAIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCAGCCGA AAGCAAGTCT CCCACAGAGC TCTGCCAGTG AAGCGGTTCA CGGCAAGTCG 60
GCGGTTTGGA TCGGAAAGGT TTTGAAACTC ATCCACAGTT ACGCGCAGTA TGCTTGAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

KEGG

ocu:100342747

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	96.37	0.00e+00	966.00
IUUC-Apl-003647	Anas platyrhynchos	94.35	0.00e+00	940.00
IUUC-Aca-004759	Anolis carolinensis	93.55	0.00e+00	951.00
IUUC-Ame-011103	Astyanax mexicanus	56.63	9.00e-144	503.00
IUUC-Bta-012718	Bos taurus	95.77	0.00e+00	958.00
IUUC-Cel-018499	Caenorhabditis elegans	42.17	4.00e-96	344.00
IUUC-Cja-019492	Callithrix jacchus	96.77	0.00e+00	998.00
IUUC-Cfa-020199	Canis familiaris	95.97	0.00e+00	995.00
IUUC-Cpo-022500	Cavia porcellus	92.34	0.00e+00	952.00
IUUC-Csa-023567	Chlorocebus sabaeus	97.58	0.00e+00	1004.00
IUUC-Cho-025071	Choloepus hoffmanni	69.56	0.00e+00	652.00
IUUC-Cin-025460	Ciona intestinalis	44.75	5.00e-104	371.00
IUUC-Csv-026042	Ciona savignyi	46.65	4.00e-109	387.00
IUUC-Dre-028214	Danio rerio	82.46	0.00e+00	861.00
IUUC-Dno-029826	Dasypus novemcinctus	96.63	0.00e+00	832.00
IUUC-Dor-030967	Dipodomys ordii	97.57	0.00e+00	902.00
IUUC-Dme-031936	Drosophila melanogaster	49.68	1.00e-118	419.00
IUUC-Ete-032452	Echinops telfairi	93.55	0.00e+00	956.00
IUUC-Eca-033278	Equus caballus	96.37	0.00e+00	998.00
IUUC-Eeu-034592	Erinaceus europaeus	83.67	0.00e+00	832.00
IUUC-Fca-036431	Felis catus	96.58	0.00e+00	999.00
IUUC-Fal-037149	Ficedula albicollis	93.15	0.00e+00	936.00
IUUC-Gmo-038476	Gadus morhua	79.26	0.00e+00	771.00
IUUC-Gga-041099	Gallus gallus	94.15	0.00e+00	942.00
IUUC-Gac-042374	Gasterosteus aculeatus	84.40	0.00e+00	825.00
IUUC-Ggo-044683	Gorilla gorilla	89.11	0.00e+00	907.00
IUUC-Hsa-046658	Homo sapiens	96.77	0.00e+00	997.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	99.12	0.00e+00	937.00
IUUC-Lch-050571	Latimeria chalumnae	85.20	0.00e+00	881.00
IUUC-Loc-052652	Lepisosteus oculatus	82.44	0.00e+00	865.00
IUUC-Laf-053712	Loxodonta africana	95.99	0.00e+00	986.00
IUUC-Mcc-055521	Macaca mulatta	97.58	0.00e+00	1004.00
IUUC-Meu-056324	Macropus eugenii	90.12	0.00e+00	892.00
IUUC-Mga-060114	Meleagris gallopavo	94.35	0.00e+00	949.00
IUUC-Mmr-061176	Microcebus murinus	96.98	0.00e+00	995.00
IUUC-Mdo-061888	Monodelphis domestica	94.96	0.00e+00	934.00
IUUC-Mmu-063977	Mus musculus	97.98	0.00e+00	1011.00
IUUC-Mpu-066220	Mustela putorius furo	82.62	0.00e+00	630.00
IUUC-Mlu-068155	Myotis lucifugus	96.57	0.00e+00	1001.00
IUUC-Nle-069964	Nomascus leucogenys	96.98	0.00e+00	999.00
IUUC-Opr-070925	Ochotona princeps	97.83	1.00e-154	539.00
IUUC-Ont-071317	Oreochromis niloticus	86.09	0.00e+00	847.00
IUUC-Oan-072952	Ornithorhynchus anatinus	95.16	0.00e+00	958.00
IUUC-Ola-087024	Oryzias latipes	84.91	0.00e+00	885.00
IUUC-Oga-087945	Otolemur garnettii	96.57	0.00e+00	1004.00
IUUC-Oar-089854	Ovis aries	95.77	0.00e+00	947.00
IUUC-Ptr-091486	Pan troglodytes	96.98	0.00e+00	999.00
IUUC-Pan-091738	Papio anubis	97.58	0.00e+00	1004.00
IUUC-Psi-093953	Pelodiscus sinensis	93.95	0.00e+00	943.00
IUUC-Pma-094560	Petromyzon marinus	76.13	0.00e+00	773.00
IUUC-Pfo-097222	Poecilia formosa	82.86	0.00e+00	832.00
IUUC-Pab-098778	Pongo abelii	92.34	0.00e+00	939.00
IUUC-Pca-100852	Procavia capensis	92.34	0.00e+00	933.00
IUUC-Pva-103130	Pteropus vampyrus	95.87	4.00e-135	474.00
IUUC-Rno-105848	Rattus norvegicus	88.51	0.00e+00	892.00
IUUC-Sha-106750	Sarcophilus harrisii	95.36	0.00e+00	962.00
IUUC-Sar-113749	Sorex araneus	87.70	0.00e+00	884.00
IUUC-Ssc-115691	Sus scrofa	93.95	0.00e+00	937.00
IUUC-Tgu-117365	Taeniopygia guttata	92.54	0.00e+00	891.00
IUUC-Tru-117595	Takifugu rubripes	84.07	0.00e+00	837.00
IUUC-Tsy-118973	Tarsius syrichta	75.82	8.00e-154	536.00
IUUC-Tni-120545	Tetraodon nigroviridis	83.53	0.00e+00	871.00
IUUC-Tbe-127976	Tupaia belangeri	72.98	0.00e+00	702.00
IUUC-Ttr-128472	Tursiops truncatus	93.55	0.00e+00	949.00
IUUC-Xtr-132621	Xenopus tropicalis	91.33	0.00e+00	905.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence