iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-051769

Ensembl Protein ID

ENSLOCP00000005710.1

UniProt Accession

W5MBF1; W5MBF1_LEPOC

Genbank Protein ID

ENSLOCP00000005710

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01005750

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000004758.1	ENSLOCT00000005718.1	ENSLOCP00000005710.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-30	104.3	170	204
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.40e-13	49.4	377	421
UBD/Beta-Prp	7.20e-48	163.4	136	381

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Ht+ v++l f +d   +lvs+s D+t++vWDl+++
   Q: 170  HTELVRDLTFaPDgsLMLVSASKDKTLRVWDLKDD 204
           9**********7767889*************9887 PP

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
            +w +++   SLqhLCR+a rr ++++++     LP+P+ + dYL+y+
   Q: 377  HFWACPQTIASLQHLCRMALRRVMPTDKV---RMLPIPPPMVDYLSYK 421
           69************************999...***************8 PP

UBD/Beta-Prp

   S: 17   kfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfs 103
            f +d+ llatg  +g+ik+wdv tgkll  l +h++ v++++f pdg+ +lv++s+D+t++vwdl+ +g +v +l+gh++ v++++fs
   Q: 136  RFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLMDHTELVRDLTFAPDGSlMLVSASKDKTLRVWDLKdDGNMVKVLRGHQNWVYCCAFS 224
           5678999******************************************99***************989******************** PP
   S: 104  psgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tgght 180
           p++++l s ++ + + +w++++++ ++  l+gh+  v + +++pdg ll+++s+D+ v +Wd  tg++lr++             g+++
   Q: 225  PDSSVLCSVGAGKAVFLWNMDKYTLIR-KLEGHHNDVVSCEFSPDGALLATASYDTRVIVWDPHTGSVLREFghlfpppspifaGGAND 312
           ***************************.999999999999*******************************************9888** PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           + v+s++f ++g +++s+ +d+ +++w++++++   + ++  +n ++ +fs  + +l+ g+  gs+ +W +
   Q: 313  RWVRSVAFCHDGLHIASVTDDKLIRFWSIEEKS--PQAIAPLTNGLCSAFSTGGSILAAGTRNGSVHFWAC 381
           *****************************9996..8899******************************55 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MASFPDFVNE NEIAKAQFIG ELLVPVAPFD QKSGRETWTV AFAPDGSYFA WSQGHRVVRL 60
VPWTSCLSNF SVGSTDLSSA AGSRRLSRQN SDGQLQKNVP REHTIDCGDI VWGLAFGSSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAAGCT TCCCAGATTT TGTAAACGAA AATGAAATAG GTAAGTTATA CTTCTTCATG 60
TATACTGTAA TGTCAGTGTA TCTGTGGGGT TTGGGGTTGA AAGGGAGGGG GTACAGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001496--SOCS_box
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	77.67	0.00e+00	681.00
IUUC-Apl-003903	Anas platyrhynchos	75.24	0.00e+00	676.00
IUUC-Aca-005214	Anolis carolinensis	67.14	8.00e-176	609.00
IUUC-Ame-011740	Astyanax mexicanus	83.65	0.00e+00	749.00
IUUC-Bta-013475	Bos taurus	77.91	0.00e+00	686.00
IUUC-Cja-019053	Callithrix jacchus	77.49	0.00e+00	697.00
IUUC-Cfa-020103	Canis familiaris	77.91	0.00e+00	684.00
IUUC-Cpo-022438	Cavia porcellus	76.72	0.00e+00	689.00
IUUC-Csa-024062	Chlorocebus sabaeus	77.67	0.00e+00	700.00
IUUC-Cho-024334	Choloepus hoffmanni	70.62	2.00e-173	602.00
IUUC-Cin-025590	Ciona intestinalis	41.06	3.00e-79	288.00
IUUC-Csv-026023	Ciona savignyi	40.81	3.00e-76	278.00
IUUC-Dre-028089	Danio rerio	86.46	0.00e+00	763.00
IUUC-Dno-029436	Dasypus novemcinctus	79.75	1.00e-164	572.00
IUUC-Dor-031107	Dipodomys ordii	72.45	7.00e-178	616.00
IUUC-Ete-032326	Echinops telfairi	77.59	0.00e+00	659.00
IUUC-Eca-033401	Equus caballus	78.38	0.00e+00	686.00
IUUC-Eeu-034520	Erinaceus europaeus	76.01	0.00e+00	688.00
IUUC-Fca-036386	Felis catus	77.67	0.00e+00	684.00
IUUC-Fal-036616	Ficedula albicollis	75.74	0.00e+00	662.00
IUUC-Gmo-039335	Gadus morhua	78.38	0.00e+00	664.00
IUUC-Gga-040856	Gallus gallus	77.20	0.00e+00	699.00
IUUC-Gac-042140	Gasterosteus aculeatus	80.94	0.00e+00	726.00
IUUC-Ggo-044619	Gorilla gorilla	77.67	0.00e+00	702.00
IUUC-Hsa-046300	Homo sapiens	77.67	0.00e+00	700.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	77.20	0.00e+00	693.00
IUUC-Lch-049550	Latimeria chalumnae	78.17	1.00e-165	575.00
IUUC-Laf-054576	Loxodonta africana	78.38	0.00e+00	682.00
IUUC-Mcc-054666	Macaca mulatta	77.78	5.00e-127	446.00
IUUC-Meu-055989	Macropus eugenii	77.01	9.00e-165	572.00
IUUC-Mga-059722	Meleagris gallopavo	76.57	0.00e+00	685.00
IUUC-Mmr-060970	Microcebus murinus	77.43	0.00e+00	678.00
IUUC-Mdo-062249	Monodelphis domestica	66.11	9.00e-156	543.00
IUUC-Mmu-063742	Mus musculus	74.17	0.00e+00	672.00
IUUC-Mpu-066518	Mustela putorius furo	77.43	0.00e+00	700.00
IUUC-Mlu-068063	Myotis lucifugus	77.20	0.00e+00	673.00
IUUC-Nle-069561	Nomascus leucogenys	77.67	0.00e+00	700.00
IUUC-Opr-071158	Ochotona princeps	74.64	0.00e+00	668.00
IUUC-Ont-072542	Oreochromis niloticus	80.71	0.00e+00	712.00
IUUC-Oan-073217	Ornithorhynchus anatinus	78.49	0.00e+00	701.00
IUUC-Ocu-074251	Oryctolagus cuniculus	77.02	0.00e+00	666.00
IUUC-Ola-086549	Oryzias latipes	78.12	0.00e+00	701.00
IUUC-Oga-088382	Otolemur garnettii	77.43	0.00e+00	680.00
IUUC-Oar-090263	Ovis aries	76.25	0.00e+00	683.00
IUUC-Ptr-090922	Pan troglodytes	77.67	0.00e+00	701.00
IUUC-Pan-092518	Papio anubis	77.67	0.00e+00	700.00
IUUC-Psi-093512	Pelodiscus sinensis	78.15	0.00e+00	697.00
IUUC-Pma-094324	Petromyzon marinus	56.91	4.00e-136	477.00
IUUC-Pfo-096264	Poecilia formosa	80.00	0.00e+00	719.00
IUUC-Pab-098018	Pongo abelii	76.25	0.00e+00	685.00
IUUC-Pca-101034	Procavia capensis	76.66	0.00e+00	634.00
IUUC-Pva-102862	Pteropus vampyrus	75.06	2.00e-180	625.00
IUUC-Rno-106116	Rattus norvegicus	75.77	0.00e+00	686.00
IUUC-Sha-106952	Sarcophilus harrisii	75.31	0.00e+00	645.00
IUUC-Sar-113211	Sorex araneus	70.85	4.00e-126	444.00
IUUC-Ssc-116440	Sus scrofa	77.91	0.00e+00	683.00
IUUC-Tgu-116675	Taeniopygia guttata	75.74	0.00e+00	662.00
IUUC-Tru-118295	Takifugu rubripes	77.88	0.00e+00	686.00
IUUC-Tsy-118916	Tarsius syrichta	66.98	3.00e-163	568.00
IUUC-Tni-120302	Tetraodon nigroviridis	79.06	0.00e+00	689.00
IUUC-Tbe-127416	Tupaia belangeri	66.09	5.00e-156	543.00
IUUC-Ttr-128185	Tursiops truncatus	78.15	0.00e+00	686.00
IUUC-Xtr-132465	Xenopus tropicalis	76.07	0.00e+00	694.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence