iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093512

Ensembl Protein ID

ENSPSIP00000018891.1

UniProt Accession

K7GF30; K7GF30_PELSI

Genbank Protein ID

ENSPSIP00000018891

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01199278

Gene Name

WSB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000016749.1	ENSPSIT00000018977.1	ENSPSIP00000018891.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	5.50e-13	48.6	375	420
E3 adaptor/Cullin RING/DCX/DWD	9.70e-32	107.7	169	203
UBD/Beta-Prp	4.10e-47	160.8	134	381

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
           +++w ++ ++ SLqhLCR+aIrr +++ ++     LP P++  ++L+y+
   Q: 375  VYFWATPKHVSSLQHLCRMAIRRVMPTSQV---RNLPVPSKVVEFLSYQ 420
           689************************777...**************98 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Ht+ v++l f +d   +lvs+s+D+t++vWDl+++
   Q: 169  HTEVVRDLTFaPDgsLILVSASRDKTLRVWDLKDD 203
           9**********8865668*************9987 PP

UBD/Beta-Prp

   S: 16   vkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsf 102
            kf +d+ llatg  +g+ik+wd+ tgkll  l +h++ v++++f pdg+ ilv++s+D+t++vwdl+ +g ++ +l+gh++ v+ ++f
   Q: 134  FKFGQDQLLLATGLNNGRIKIWDAYTGKLLLNLMDHTEVVRDLTFAPDGSlILVSASRDKTLRVWDLKdDGNMMKVLRGHQNWVYGCAF 222
           68899999***********************************************************9799****************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tggh 179
           sp+++ l s ++ + + +wd+++++ ++  l+gh+  v   +++pdg ll+++s+D+ v +Wd   g +l ++             g++
   Q: 223  SPDSSILCSVGASKAVFLWDMDKYTMIR-KLEGHHNDVVACEFSPDGALLATASYDTRVYVWDPHIGVILMEFghlfpaptpifaGGAN 310
           ****************************.999999999999*******************************************9888* PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsg 254
           ++ v+s+sf+++g +++s ++d+ v++w++++      + +  +n ++ +fs ++  l+ g++Dgs+++W   + 
   Q: 311  DRWVRSVSFSHDGLHIASLADDKMVRFWSIEED--YPVQVAPLSNGLCCAFSTDGSVLAAGTHDGSVYFWA--TP 381
           ******************************988..68899******************************3..33 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MASFPPSVNE KLIARSRPIG ELLAPTSPFD KKCGRENWTV AFAPDGSYFA WSQGHRIVKL 60
VPWTQCFNNF LLHGTKNVPN SVNSRLSRQN SDSGQKNKPC EHIIDCGDIV WSLAFGSSVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGCGGTGG TTGTGGTTCC CCTCGCTCAG TCCCTCAGCG CCCCGACCCG TGTCAGAGCC 60
GGTCCGAAGG GCGGCTCCGT AGATGGCCAG CTTTCCCCCG AGTGTCAACG AGAAGCTCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

KEGG

pss:102446813

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	89.79	0.00e+00	778.00
IUUC-Apl-003903	Anas platyrhynchos	93.66	0.00e+00	809.00
IUUC-Aca-005214	Anolis carolinensis	79.81	0.00e+00	715.00
IUUC-Ame-011740	Astyanax mexicanus	76.01	0.00e+00	681.00
IUUC-Bta-013475	Bos taurus	89.79	0.00e+00	781.00
IUUC-Cja-019053	Callithrix jacchus	89.52	0.00e+00	791.00
IUUC-Cfa-020103	Canis familiaris	89.79	0.00e+00	778.00
IUUC-Cpo-022438	Cavia porcellus	89.07	0.00e+00	789.00
IUUC-Csa-024062	Chlorocebus sabaeus	90.02	0.00e+00	796.00
IUUC-Cho-024334	Choloepus hoffmanni	78.38	0.00e+00	655.00
IUUC-Cin-025590	Ciona intestinalis	40.45	4.00e-79	288.00
IUUC-Csv-026023	Ciona savignyi	39.23	1.00e-76	280.00
IUUC-Dre-028089	Danio rerio	75.30	0.00e+00	676.00
IUUC-Dno-029436	Dasypus novemcinctus	86.23	0.00e+00	637.00
IUUC-Dor-031107	Dipodomys ordii	82.42	0.00e+00	693.00
IUUC-Ete-032326	Echinops telfairi	87.96	0.00e+00	741.00
IUUC-Eca-033401	Equus caballus	89.55	0.00e+00	775.00
IUUC-Eeu-034520	Erinaceus europaeus	87.41	0.00e+00	780.00
IUUC-Fca-036386	Felis catus	89.55	0.00e+00	777.00
IUUC-Fal-036616	Ficedula albicollis	89.46	0.00e+00	775.00
IUUC-Gmo-039335	Gadus morhua	72.24	3.00e-179	620.00
IUUC-Gga-040856	Gallus gallus	93.11	0.00e+00	824.00
IUUC-Gac-042140	Gasterosteus aculeatus	74.18	0.00e+00	664.00
IUUC-Ggo-044619	Gorilla gorilla	89.31	0.00e+00	795.00
IUUC-Hsa-046300	Homo sapiens	89.31	0.00e+00	793.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	88.84	0.00e+00	788.00
IUUC-Lch-049550	Latimeria chalumnae	80.92	2.00e-170	591.00
IUUC-Loc-051769	Lepisosteus oculatus	78.15	0.00e+00	688.00
IUUC-Laf-054576	Loxodonta africana	90.02	0.00e+00	776.00
IUUC-Mcc-054666	Macaca mulatta	88.85	7.00e-144	502.00
IUUC-Meu-055989	Macropus eugenii	89.14	0.00e+00	642.00
IUUC-Mga-059722	Meleagris gallopavo	91.79	0.00e+00	805.00
IUUC-Mmr-060970	Microcebus murinus	89.55	0.00e+00	773.00
IUUC-Mdo-062249	Monodelphis domestica	76.89	0.00e+00	626.00
IUUC-Mmu-063742	Mus musculus	85.95	0.00e+00	764.00
IUUC-Mpu-066518	Mustela putorius furo	89.07	0.00e+00	796.00
IUUC-Mlu-068063	Myotis lucifugus	89.07	0.00e+00	768.00
IUUC-Nle-069561	Nomascus leucogenys	89.31	0.00e+00	793.00
IUUC-Opr-071158	Ochotona princeps	85.71	0.00e+00	757.00
IUUC-Ont-072542	Oreochromis niloticus	73.71	0.00e+00	657.00
IUUC-Oan-073217	Ornithorhynchus anatinus	90.74	0.00e+00	793.00
IUUC-Ocu-074251	Oryctolagus cuniculus	88.54	0.00e+00	754.00
IUUC-Ola-086549	Oryzias latipes	72.77	0.00e+00	655.00
IUUC-Oga-088382	Otolemur garnettii	89.79	0.00e+00	783.00
IUUC-Oar-090263	Ovis aries	88.12	0.00e+00	778.00
IUUC-Ptr-090922	Pan troglodytes	89.55	0.00e+00	795.00
IUUC-Pan-092518	Papio anubis	90.02	0.00e+00	796.00
IUUC-Pma-094324	Petromyzon marinus	57.64	3.00e-135	474.00
IUUC-Pfo-096264	Poecilia formosa	73.00	0.00e+00	656.00
IUUC-Pab-098018	Pongo abelii	87.89	0.00e+00	778.00
IUUC-Pca-101034	Procavia capensis	87.96	0.00e+00	722.00
IUUC-Pva-102862	Pteropus vampyrus	85.27	0.00e+00	709.00
IUUC-Rno-106116	Rattus norvegicus	87.41	0.00e+00	777.00
IUUC-Sha-106952	Sarcophilus harrisii	88.26	0.00e+00	736.00
IUUC-Sar-113211	Sorex araneus	80.19	5.00e-144	503.00
IUUC-Ssc-116440	Sus scrofa	90.02	0.00e+00	780.00
IUUC-Tgu-116675	Taeniopygia guttata	90.69	0.00e+00	779.00
IUUC-Tru-118295	Takifugu rubripes	72.54	0.00e+00	636.00
IUUC-Tsy-118916	Tarsius syrichta	78.15	0.00e+00	654.00
IUUC-Tni-120302	Tetraodon nigroviridis	71.60	0.00e+00	629.00
IUUC-Tbe-127416	Tupaia belangeri	78.13	0.00e+00	631.00
IUUC-Ttr-128185	Tursiops truncatus	89.55	0.00e+00	778.00
IUUC-Xtr-132465	Xenopus tropicalis	84.76	0.00e+00	752.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence