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Tag Content
UUCD2 ID IUUC-Tru-118731
UUCD1 version UUC-TaR-00824
Ensembl Protein ID ENSTRUP00000038596.1
UniProt Accession H2UNS5; H2UNS5_TAKRU
Protein Name Uncharacterized protein
Gene Name cbl (1 of many); cbl
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSTRUG00000015111.1 ENSTRUT00000038734.1 ENSTRUP00000038595.1
ENSTRUG00000015111.1 ENSTRUT00000038735.1 ENSTRUP00000038596.1
ENSTRUG00000015111.1 ENSTRUT00000038736.1 ENSTRUP00000038597.1
ENSTRUG00000015111.1 ENSTRUT00000038737.1 ENSTRUP00000038598.1
ENSTRUG00000015111.1 ENSTRUT00000038738.1 ENSTRUP00000038599.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 1.90e-07 32.7 365 406
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl +w   + s+ +   CP Cr
   Q: 365  CKICAENDKD-VKIEPCGHLMCTSCLTAW---QESEGQGTGCPFCR 406
           99********.******************...333666666****8 PP
   
Organism Takifugu rubripes
Protein Sequence
(Fasta)
MAGNLKKGGG LIGMMKVTFQ PHHHHLHSHH QPGAVDKKTV EKCWKLMDKV VRLCQNPKLA 60
LKNSPPYILD LLPDTYQHLR TILSRYEGKM ETLGENEYFR VFMENLTKKT KQTISLFKEG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Tru-118731|E3,RING|Takifugu rubripes
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACCATGGCAG GAAACCTAAA GAAAGGTGGA GGGCTCATTG GAATGATGAA GGTTACTTTC 60
CAGCCACACC ATCACCACCT CCACTCCCAT CACCAACCTG GAGCCGTGGA CAAAAAGACA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Tru-118731|E3,RING|Takifugu rubripes
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR009060--UBA-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3
PF00627--UBA
SMART

SM00184--RING
SM00165--UBA
Gene Ontology

GO:0045121--C:membrane raft
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0030971--F:receptor tyrosine kinase binding
GO:0017124--F:SH3 domain binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0006508--P:proteolysis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002357 Ailuropoda melanoleuca 67.33 0.00e+00 1006.00
IUUC-Apl-004041 Anas platyrhynchos 68.87 0.00e+00 1066.00
IUUC-Aca-004899 Anolis carolinensis 67.25 0.00e+00 1005.00
IUUC-Ame-010746 Astyanax mexicanus 62.14 0.00e+00 717.00
IUUC-Bta-012759 Bos taurus 67.68 0.00e+00 1041.00
IUUC-Cja-019207 Callithrix jacchus 67.39 0.00e+00 1067.00
IUUC-Cfa-020897 Canis familiaris 66.81 0.00e+00 1058.00
IUUC-Cpo-021453 Cavia porcellus 67.11 0.00e+00 1036.00
IUUC-Csa-023136 Chlorocebus sabaeus 67.46 0.00e+00 1067.00
IUUC-Cho-024282 Choloepus hoffmanni 59.67 0.00e+00 852.00
IUUC-Cin-025574 Ciona intestinalis 70.99 9.00e-179 619.00
IUUC-Csv-025938 Ciona savignyi 69.37 4.00e-173 600.00
IUUC-Dre-027644 Danio rerio 77.14 0.00e+00 1168.00
IUUC-Dno-030025 Dasypus novemcinctus 67.22 0.00e+00 1013.00
IUUC-Dme-032213 Drosophila melanogaster 74.17 0.00e+00 639.00
IUUC-Eca-033900 Equus caballus 67.37 0.00e+00 1019.00
IUUC-Eeu-035142 Erinaceus europaeus 70.15 0.00e+00 723.00
IUUC-Fca-035455 Felis catus 65.46 0.00e+00 1038.00
IUUC-Fal-037182 Ficedula albicollis 91.28 0.00e+00 824.00
IUUC-Gmo-038698 Gadus morhua 92.40 0.00e+00 910.00
IUUC-Gga-040438 Gallus gallus 68.61 0.00e+00 1075.00
IUUC-Gac-042166 Gasterosteus aculeatus 81.13 0.00e+00 1176.00
IUUC-Ggo-045618 Gorilla gorilla 67.32 0.00e+00 1065.00
IUUC-Hsa-046177 Homo sapiens 67.32 0.00e+00 1064.00
IUUC-Itr-048795 Ictidomys tridecemlineatus 74.29 0.00e+00 727.00
IUUC-Lch-050095 Latimeria chalumnae 68.85 0.00e+00 1107.00
IUUC-Loc-052570 Lepisosteus oculatus 77.32 0.00e+00 1194.00
IUUC-Laf-054008 Loxodonta africana 67.01 0.00e+00 1071.00
IUUC-Mcc-054676 Macaca mulatta 67.56 0.00e+00 1070.00
IUUC-Mga-059239 Meleagris gallopavo 69.67 0.00e+00 1099.00
IUUC-Mmr-060907 Microcebus murinus 65.97 0.00e+00 1037.00
IUUC-Mdo-062595 Monodelphis domestica 68.33 0.00e+00 1025.00
IUUC-Mmu-063725 Mus musculus 66.53 0.00e+00 1083.00
IUUC-Mpu-066771 Mustela putorius furo 66.80 0.00e+00 1047.00
IUUC-Mlu-067206 Myotis lucifugus 73.53 0.00e+00 829.00
IUUC-Nle-069285 Nomascus leucogenys 66.22 0.00e+00 999.00
IUUC-Opr-071026 Ochotona princeps 67.55 0.00e+00 1034.00
IUUC-Ont-071954 Oreochromis niloticus 81.44 0.00e+00 1250.00
IUUC-Ocu-074657 Oryctolagus cuniculus 66.63 0.00e+00 1001.00
IUUC-Ola-087165 Oryzias latipes 79.54 0.00e+00 1326.00
IUUC-Oga-088198 Otolemur garnettii 70.60 0.00e+00 928.00
IUUC-Oar-090258 Ovis aries 66.85 0.00e+00 993.00
IUUC-Ptr-090710 Pan troglodytes 67.32 0.00e+00 1064.00
IUUC-Pan-092785 Papio anubis 67.56 0.00e+00 1067.00
IUUC-Pma-094249 Petromyzon marinus 80.33 9.00e-123 432.00
IUUC-Pfo-096990 Poecilia formosa 84.89 0.00e+00 1278.00
IUUC-Pab-098526 Pongo abelii 67.50 0.00e+00 1066.00
IUUC-Pva-102352 Pteropus vampyrus 86.04 0.00e+00 817.00
IUUC-Rno-105876 Rattus norvegicus 66.67 0.00e+00 1074.00
IUUC-Sha-107588 Sarcophilus harrisii 65.13 0.00e+00 885.00
IUUC-Sar-112959 Sorex araneus 66.22 0.00e+00 1005.00
IUUC-Ssc-115261 Sus scrofa 66.84 0.00e+00 1053.00
IUUC-Tgu-116580 Taeniopygia guttata 67.71 0.00e+00 1060.00
IUUC-Tsy-118982 Tarsius syrichta 55.70 0.00e+00 627.00
IUUC-Tni-120725 Tetraodon nigroviridis 83.98 0.00e+00 1338.00
IUUC-Tbe-128018 Tupaia belangeri 76.97 0.00e+00 889.00
IUUC-Ttr-128927 Tursiops truncatus 67.37 0.00e+00 1070.00
IUUC-Vpa-130369 Vicugna pacos 66.45 0.00e+00 964.00
IUUC-Xtr-132474 Xenopus tropicalis 65.89 0.00e+00 1026.00
Created Date 25-Jun-2017

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