iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Atr-002857

Ensembl Protein ID

ERM93648

UniProt Accession

W1NE48; W1NE48_AMBTC

Genbank Protein ID

ERM93648.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

KI397628

Gene Name

AMTR_s00004p00156470

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AMTR_s00004p00156470	ERM93648	ERM93648

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	37.01	8.00e-42	167.00	IUUC-Dme-031700
E3 activity/RING/RING	36.19	4.00e-43	172.00	IUUC-Hsa-046357

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Amborella trichopoda

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MDDPRSLPGD ADSSLVSGND QPCVVPSKIL NGRKPIVLPN SDIDGLLECP VCSSSMYPPI 60
QQCPSGHTIC FDCKAKVNNK CPICRKEIGN IRCLALEKLA VSLHLPCAYH RLGCEEMFPY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGATC CCAGATCACT TCCAGGTGAT GCAGATTCTT CTCTGGTATC CGGAAATGAT 60
CAGCCTTGTG TGGTTCCATC CAAGATATTA AATGGAAGGA AGCCTATTGT ATTGCCTAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001186	Ailuropoda melanoleuca	36.06	7.00e-45	172.00
IUUC-Apl-003813	Anas platyrhynchos	36.06	6.00e-45	172.00
IUUC-Aca-005014	Anolis carolinensis	36.06	8.00e-45	172.00
IUUC-Ame-011196	Astyanax mexicanus	36.43	4.00e-45	174.00
IUUC-Bta-012887	Bos taurus	36.06	8.00e-45	172.00
IUUC-Cja-019796	Callithrix jacchus	36.19	1.00e-44	172.00
IUUC-Cfa-020642	Canis familiaris	36.06	6.00e-45	173.00
IUUC-Cpo-022348	Cavia porcellus	36.19	8.00e-45	172.00
IUUC-Csa-023974	Chlorocebus sabaeus	36.19	8.00e-45	172.00
IUUC-Cho-024933	Choloepus hoffmanni	36.36	6.00e-41	159.00
IUUC-Cin-025674	Ciona intestinalis	37.70	1.00e-45	174.00
IUUC-Csv-026233	Ciona savignyi	37.30	5.00e-45	172.00
IUUC-Dre-028041	Danio rerio	36.57	3.00e-45	174.00
IUUC-Dno-029764	Dasypus novemcinctus	34.48	4.00e-45	174.00
IUUC-Dor-030489	Dipodomys ordii	34.59	4.00e-25	106.00
IUUC-Dme-031700	Drosophila melanogaster	37.30	2.00e-39	155.00
IUUC-Ete-032423	Echinops telfairi	35.51	2.00e-44	171.00
IUUC-Eca-033536	Equus caballus	36.06	6.00e-45	172.00
IUUC-Eeu-035314	Erinaceus europaeus	37.25	6.00e-44	170.00
IUUC-Fca-035362	Felis catus	36.06	7.00e-45	172.00
IUUC-Fal-037487	Ficedula albicollis	36.06	8.00e-45	172.00
IUUC-Gmo-039091	Gadus morhua	35.90	5.00e-40	156.00
IUUC-Gga-040269	Gallus gallus	36.06	6.00e-45	172.00
IUUC-Gac-042282	Gasterosteus aculeatus	36.57	3.00e-45	174.00
IUUC-Ggo-045444	Gorilla gorilla	36.19	8.00e-45	172.00
IUUC-Hsa-046357	Homo sapiens	36.19	8.00e-45	172.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	36.19	8.00e-45	172.00
IUUC-Lch-049504	Latimeria chalumnae	36.06	6.00e-45	172.00
IUUC-Loc-052191	Lepisosteus oculatus	36.06	8.00e-45	172.00
IUUC-Laf-053668	Loxodonta africana	36.06	6.00e-45	172.00
IUUC-Mcc-054640	Macaca mulatta	36.19	8.00e-45	172.00
IUUC-Meu-055922	Macropus eugenii	35.97	1.00e-39	155.00
IUUC-Mga-059503	Meleagris gallopavo	36.06	7.00e-45	172.00
IUUC-Mmr-060794	Microcebus murinus	36.19	8.00e-45	172.00
IUUC-Mdo-061971	Monodelphis domestica	36.76	3.00e-41	160.00
IUUC-Mmu-063876	Mus musculus	35.21	3.00e-45	174.00
IUUC-Mpu-066488	Mustela putorius furo	36.06	8.00e-45	172.00
IUUC-Mlu-067207	Myotis lucifugus	36.06	6.00e-45	172.00
IUUC-Nle-069706	Nomascus leucogenys	36.19	1.00e-44	172.00
IUUC-Ont-071849	Oreochromis niloticus	36.57	3.00e-45	174.00
IUUC-Ocu-074876	Oryctolagus cuniculus	36.19	1.00e-44	172.00
IUUC-Ola-086814	Oryzias latipes	36.57	3.00e-45	174.00
IUUC-Oga-088399	Otolemur garnettii	36.19	8.00e-45	172.00
IUUC-Oar-089323	Ovis aries	36.06	8.00e-45	172.00
IUUC-Ptr-090692	Pan troglodytes	36.19	1.00e-44	172.00
IUUC-Pan-092012	Papio anubis	36.19	8.00e-45	172.00
IUUC-Psi-093687	Pelodiscus sinensis	36.06	7.00e-45	172.00
IUUC-Pma-094387	Petromyzon marinus	33.68	4.00e-45	173.00
IUUC-Pfo-097134	Poecilia formosa	36.57	3.00e-45	174.00
IUUC-Pab-097555	Pongo abelii	36.19	8.00e-45	172.00
IUUC-Pca-100328	Procavia capensis	35.97	8.00e-39	152.00
IUUC-Pva-102368	Pteropus vampyrus	34.91	3.00e-13	67.80
IUUC-Rno-104866	Rattus norvegicus	36.19	6.00e-45	172.00
IUUC-Sha-106547	Sarcophilus harrisii	36.06	8.00e-45	172.00
IUUC-Ssc-116441	Sus scrofa	36.36	5.00e-41	160.00
IUUC-Tgu-116579	Taeniopygia guttata	36.06	6.00e-45	172.00
IUUC-Tru-118250	Takifugu rubripes	36.19	6.00e-44	169.00
IUUC-Tsy-119548	Tarsius syrichta	32.99	3.00e-09	54.30
IUUC-Tni-120488	Tetraodon nigroviridis	37.07	2.00e-42	164.00
IUUC-Ttr-129166	Tursiops truncatus	38.33	5.00e-42	163.00
IUUC-Vpa-130799	Vicugna pacos	35.09	1.00e-23	101.00
IUUC-Xtr-132553	Xenopus tropicalis	36.19	7.00e-45	172.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence