iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121228

Ensembl Protein ID

EOY19911

UniProt Accession

A0A061FS43; A0A061FS43_THECC

Genbank Protein ID

EOY19911.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

CM001888

Gene Name

TCM_045318

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_045318	EOY19911	EOY19911

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	35.69	7.00e-40	161.00	IUUC-Dme-031700
E3 activity/RING/RING	35.50	8.00e-40	161.00	IUUC-Hsa-046357
E3 activity/RING/RING	35.50	4.00e-40	162.00	IUUC-Mmu-064129

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Theobroma cacao

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MASGNAFFDE LRSKPEVIDP PQNEDIIDSE SVNDPTQAAI KPNVTVSSSV RELLECPVCL 60
NAMYPPIHQC SNGHTLCSGC KPRVHNRCPT CRHELGNIRC LALEKVAASL ELPCKYQSFG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAGGAAGCT CACATCCAAC CCGACACCTT AAATACTGGG CGATGCCGTC CGCTGTATTC 60
CCGGTGCCGG TCGACAGCCT CCTTCCCATT TTCATTTCAA AAATCAAATC TCTTTCTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000061	Aegilops tauschii	73.21	2.00e-126	444.00
IUUC-Aml-001186	Ailuropoda melanoleuca	35.50	2.00e-41	161.00
IUUC-Atr-003118	Amborella trichopoda	85.25	1.00e-159	554.00
IUUC-Apl-003813	Anas platyrhynchos	35.50	2.00e-41	161.00
IUUC-Aca-005014	Anolis carolinensis	33.33	2.00e-41	162.00
IUUC-Ame-011196	Astyanax mexicanus	34.01	6.00e-42	163.00
IUUC-Bta-012887	Bos taurus	33.44	2.00e-41	161.00
IUUC-Cel-018320	Caenorhabditis elegans	33.46	1.00e-36	146.00
IUUC-Cja-019796	Callithrix jacchus	35.50	2.00e-41	161.00
IUUC-Cfa-020642	Canis familiaris	35.50	1.00e-41	162.00
IUUC-Cpo-022348	Cavia porcellus	35.50	2.00e-41	161.00
IUUC-Csa-023974	Chlorocebus sabaeus	35.50	2.00e-41	161.00
IUUC-Cho-024933	Choloepus hoffmanni	34.66	1.00e-37	149.00
IUUC-Cin-025674	Ciona intestinalis	35.74	1.00e-42	166.00
IUUC-Csv-026233	Ciona savignyi	36.14	7.00e-43	166.00
IUUC-Dre-028041	Danio rerio	34.01	8.00e-42	163.00
IUUC-Dno-029764	Dasypus novemcinctus	34.01	4.00e-42	164.00
IUUC-Dor-030489	Dipodomys ordii	30.27	1.00e-18	85.10
IUUC-Dme-031700	Drosophila melanogaster	34.80	7.00e-37	146.00
IUUC-Ete-032423	Echinops telfairi	34.77	1.00e-41	162.00
IUUC-Eca-033536	Equus caballus	35.50	2.00e-41	161.00
IUUC-Eeu-035314	Erinaceus europaeus	36.29	5.00e-41	160.00
IUUC-Fca-035362	Felis catus	35.50	2.00e-41	161.00
IUUC-Fal-037487	Ficedula albicollis	35.50	2.00e-41	162.00
IUUC-Gmo-039091	Gadus morhua	34.25	9.00e-37	146.00
IUUC-Gga-040269	Gallus gallus	35.50	2.00e-41	161.00
IUUC-Gac-042282	Gasterosteus aculeatus	36.61	7.00e-42	163.00
IUUC-Gma-042926	Glycine max	90.82	4.00e-169	585.00
IUUC-Ggo-045444	Gorilla gorilla	35.50	2.00e-41	161.00
IUUC-Hsa-046357	Homo sapiens	35.50	2.00e-41	161.00
IUUC-Hvu-047574	Hordeum vulgare	73.21	2.00e-126	444.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	35.50	2.00e-41	161.00
IUUC-Lch-049504	Latimeria chalumnae	35.50	2.00e-41	162.00
IUUC-Lpe-050879	Leersia perrieri	79.45	3.00e-126	443.00
IUUC-Loc-052191	Lepisosteus oculatus	33.33	9.00e-42	163.00
IUUC-Laf-053668	Loxodonta africana	35.50	2.00e-41	161.00
IUUC-Mcc-054640	Macaca mulatta	35.50	2.00e-41	161.00
IUUC-Meu-055922	Macropus eugenii	34.26	2.00e-36	145.00
IUUC-Mtr-058422	Medicago truncatula	87.21	8.00e-163	565.00
IUUC-Mga-059503	Meleagris gallopavo	35.50	2.00e-41	161.00
IUUC-Mmr-060794	Microcebus murinus	35.50	2.00e-41	161.00
IUUC-Mdo-061971	Monodelphis domestica	34.26	3.00e-37	147.00
IUUC-Mmu-064129	Mus musculus	35.50	1.00e-41	162.00
IUUC-Mpu-066488	Mustela putorius furo	35.50	2.00e-41	161.00
IUUC-Mlu-067207	Myotis lucifugus	35.50	1.00e-41	162.00
IUUC-Nle-069706	Nomascus leucogenys	35.50	2.00e-41	161.00
IUUC-Opr-070341	Ochotona princeps	25.30	2.00e-12	65.10
IUUC-Ont-071849	Oreochromis niloticus	36.61	6.00e-42	163.00
IUUC-Oan-073701	Ornithorhynchus anatinus	23.49	5.00e-12	63.90
IUUC-Ocu-074876	Oryctolagus cuniculus	35.50	3.00e-41	161.00
IUUC-Oba-075789	Oryza barthii	87.67	5.00e-161	558.00
IUUC-Obr-076037	Oryza brachyantha	87.87	7.00e-162	562.00
IUUC-Ogl-077148	Oryza glaberrima	87.67	5.00e-161	558.00
IUUC-Ogu-078042	Oryza glumaepatula	87.67	4.00e-161	559.00
IUUC-Oin-079325	Oryza indica	88.00	2.00e-161	560.00
IUUC-Olo-080244	Oryza longistaminata	87.67	2.00e-161	561.00
IUUC-Ome-081318	Oryza meridionalis	79.84	3.00e-126	443.00
IUUC-Oni-082163	Oryza nivara	87.67	5.00e-161	558.00
IUUC-Opu-084065	Oryza punctata	79.45	8.00e-126	442.00
IUUC-Oru-084833	Oryza rufipogon	88.00	2.00e-161	560.00
IUUC-Osa-085316	Oryza sativa	88.00	2.00e-161	560.00
IUUC-Ola-086814	Oryzias latipes	36.61	7.00e-42	163.00
IUUC-Oga-088114	Otolemur garnettii	36.09	5.00e-43	166.00
IUUC-Oar-089323	Ovis aries	33.44	2.00e-41	162.00
IUUC-Ptr-090692	Pan troglodytes	35.50	2.00e-41	161.00
IUUC-Pan-092012	Papio anubis	35.50	2.00e-41	161.00
IUUC-Psi-093687	Pelodiscus sinensis	35.50	2.00e-41	161.00
IUUC-Pma-094387	Petromyzon marinus	33.70	7.00e-42	163.00
IUUC-Pfo-097134	Poecilia formosa	36.61	7.00e-42	163.00
IUUC-Pab-097555	Pongo abelii	35.50	2.00e-41	161.00
IUUC-Pca-100328	Procavia capensis	35.32	2.00e-35	141.00
IUUC-Pva-103132	Pteropus vampyrus	23.31	2.00e-11	62.00
IUUC-Rno-104866	Rattus norvegicus	35.50	1.00e-41	162.00
IUUC-Sha-106547	Sarcophilus harrisii	36.00	2.00e-41	161.00
IUUC-Sit-110245	Setaria italica	89.42	2.00e-159	553.00
IUUC-Stu-112474	Solanum tuberosum	89.51	6.00e-167	578.00
IUUC-Sbi-114035	Sorghum bicolor	87.54	1.00e-160	557.00
IUUC-Ssc-116441	Sus scrofa	35.71	1.00e-37	149.00
IUUC-Tgu-116579	Taeniopygia guttata	35.50	2.00e-41	161.00
IUUC-Tru-118250	Takifugu rubripes	34.55	3.00e-41	160.00
IUUC-Tsy-119548	Tarsius syrichta	28.21	8.00e-09	53.10
IUUC-Tni-120488	Tetraodon nigroviridis	37.14	1.00e-39	155.00
IUUC-Tae-123647	Triticum aestivum	73.21	2.00e-126	444.00
IUUC-Tur-126259	Triticum urartu	85.86	4.00e-156	542.00
IUUC-Ttr-129166	Tursiops truncatus	35.56	4.00e-39	154.00
IUUC-Vpa-130799	Vicugna pacos	32.16	2.00e-18	84.00
IUUC-Vvi-131233	Vitis vinifera	72.22	1.00e-130	458.00
IUUC-Xtr-132553	Xenopus tropicalis	35.50	1.00e-41	162.00
IUUC-Xma-133670	Xiphophorus maculatus	36.61	7.00e-42	163.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence