iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132032

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01121949

Gene Name

usp18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000034297.1	ENSXETT00000064403.1	ENSXETP00000063031.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.70e-53	182.1	4	315

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle..kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgy 87
           +Gl N+g    +N +LQ+L++ + +++ll    + + ++        + +l  +l  lfee+++sk+ av+p ++l++l+ +  +    
   Q: 4    VGLCNIGVNNCLNPLLQTLYMNQHFTDLLCGigHPNDNV------PAERRLPYELLALFEEMQNSKEDAVAPYRFLRCLQILDTR--LC 84
           6999**97777*******************953333344......35679******************************99987..89 PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           eq+Da +fl ++ + l +++                          +  +  + +  l++++lk++++c +c +++s++ + l+++lpv
   Q: 85   EQHDAADFLFMMWNLLLQQM--------------------------PLPHLAQRLRALYGIKLKEHVTCHKCSHEKSSDMEVLTIPLPV 147
           ********************..........................677778899********************************** PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           p ++ + ++ lq +L  f+k++e+ ++n  +c+kc +++  ++ l++ +lP++L++hLkR+s ++ ++  +kin+ ++fp +Ldls ++
   Q: 148  PHSKYQRPLPLQRALWRFFKPHEISEDN--FCPKCAENTAGQRVLQFFSLPQTLSIHLKRISRRK-TSDVQKINRTFSFPCTLDLSDVL 233
           *************************987..*******************************6655.56667***************999 PP
   S: 266  tspeekqke....kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.......staYvlfY 335
            +++  ++e    + kY+L+av+ HsG++s GHY+ay++++k++ W+ f+Ds+V +v++++v+ + g       +ta +l+Y
   Q: 234  DQEQFPVQEhaqsDFKYRLFAVIAHSGTASFGHYCAYINSSKDQtWYSFNDSSVCKVSWDDVKCTYGnmdfhfsATACLLVY 315
           9944443334444***************************99999*****************99777888888888888888 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

TGAVGLCNIG VNNCLNPLLQ TLYMNQHFTD LLCGIGHPND NVPAERRLPY ELLALFEEMQ 60
NSKEDAVAPY RFLRCLQILD TRLCEQHDAA DFLFMMWNLL LQQMPLPHLA QRLRALYGIK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGGGGCAG TCGGACTGTG CAATATCGGG GTAAACAACT GTCTGAACCC GCTGCTACAA 60
ACTCTATACA TGAACCAGCA CTTTACAGAC TTACTCTGTG GGTAAGTACT TCTCAAGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001615	Ailuropoda melanoleuca	43.97	6.00e-68	250.00
IUUC-Apl-004006	Anas platyrhynchos	42.95	2.00e-71	262.00
IUUC-Aca-005088	Anolis carolinensis	42.19	1.00e-64	239.00
IUUC-Ame-010606	Astyanax mexicanus	34.47	2.00e-35	142.00
IUUC-Bta-013036	Bos taurus	42.06	1.00e-66	246.00
IUUC-Cja-019052	Callithrix jacchus	40.74	1.00e-58	219.00
IUUC-Cfa-020554	Canis familiaris	44.65	3.00e-72	265.00
IUUC-Cpo-022421	Cavia porcellus	42.28	1.00e-64	240.00
IUUC-Csa-023737	Chlorocebus sabaeus	43.78	2.00e-43	168.00
IUUC-Cho-024807	Choloepus hoffmanni	37.88	1.00e-28	120.00
IUUC-Dre-027408	Danio rerio	33.65	7.00e-38	150.00
IUUC-Dno-029813	Dasypus novemcinctus	34.89	3.00e-43	168.00
IUUC-Dor-030532	Dipodomys ordii	43.17	1.00e-66	246.00
IUUC-Ete-032254	Echinops telfairi	41.19	6.00e-66	244.00
IUUC-Eca-033482	Equus caballus	44.65	2.00e-71	261.00
IUUC-Eeu-034451	Erinaceus europaeus	43.66	4.00e-46	177.00
IUUC-Fca-036313	Felis catus	44.65	8.00e-72	263.00
IUUC-Fal-037216	Ficedula albicollis	43.26	2.00e-70	258.00
IUUC-Gmo-038649	Gadus morhua	30.89	2.00e-32	132.00
IUUC-Gga-041082	Gallus gallus	42.27	7.00e-67	247.00
IUUC-Gac-042439	Gasterosteus aculeatus	33.75	3.00e-37	148.00
IUUC-Ggo-044957	Gorilla gorilla	41.03	7.00e-57	213.00
IUUC-Hsa-046381	Homo sapiens	42.77	6.00e-70	257.00
IUUC-Itr-047918	Ictidomys tridecemlineatus	42.95	1.00e-68	253.00
IUUC-Loc-052688	Lepisosteus oculatus	33.22	5.00e-41	161.00
IUUC-Laf-054109	Loxodonta africana	44.34	1.00e-70	259.00
IUUC-Mcc-054814	Macaca mulatta	43.08	9.00e-71	260.00
IUUC-Meu-056253	Macropus eugenii	42.16	1.00e-50	192.00
IUUC-Mmr-061613	Microcebus murinus	43.30	3.00e-68	251.00
IUUC-Mdo-061890	Monodelphis domestica	41.01	7.00e-63	233.00
IUUC-Mmu-064329	Mus musculus	44.30	6.00e-62	231.00
IUUC-Mpu-066342	Mustela putorius furo	44.86	7.00e-73	267.00
IUUC-Mlu-067010	Myotis lucifugus	43.30	8.00e-69	253.00
IUUC-Nle-069148	Nomascus leucogenys	42.77	8.00e-70	257.00
IUUC-Opr-070988	Ochotona princeps	45.51	2.00e-34	139.00
IUUC-Ont-072039	Oreochromis niloticus	31.99	2.00e-33	136.00
IUUC-Oan-073740	Ornithorhynchus anatinus	37.63	5.00e-40	157.00
IUUC-Ocu-074498	Oryctolagus cuniculus	43.08	1.00e-61	230.00
IUUC-Ola-086753	Oryzias latipes	34.17	2.00e-38	152.00
IUUC-Oga-088497	Otolemur garnettii	44.37	2.00e-68	252.00
IUUC-Oar-089505	Ovis aries	42.50	1.00e-67	249.00
IUUC-Ptr-091656	Pan troglodytes	42.45	4.00e-69	254.00
IUUC-Pan-092498	Papio anubis	43.08	1.00e-70	259.00
IUUC-Psi-093409	Pelodiscus sinensis	43.16	1.00e-74	273.00
IUUC-Pfo-096507	Poecilia formosa	30.99	2.00e-34	139.00
IUUC-Pab-097828	Pongo abelii	41.43	6.00e-67	247.00
IUUC-Pca-100299	Procavia capensis	38.62	5.00e-31	128.00
IUUC-Pva-102972	Pteropus vampyrus	44.34	2.00e-69	255.00
IUUC-Rno-105738	Rattus norvegicus	41.19	3.00e-61	228.00
IUUC-Sha-107309	Sarcophilus harrisii	40.73	1.00e-59	223.00
IUUC-Sar-112983	Sorex araneus	42.91	6.00e-54	204.00
IUUC-Ssc-116049	Sus scrofa	41.74	5.00e-68	250.00
IUUC-Tgu-117115	Taeniopygia guttata	43.93	3.00e-71	261.00
IUUC-Tru-118022	Takifugu rubripes	32.21	6.00e-34	137.00
IUUC-Tni-120306	Tetraodon nigroviridis	31.76	2.00e-33	135.00
IUUC-Tbe-127768	Tupaia belangeri	35.86	4.00e-31	128.00
IUUC-Ttr-128686	Tursiops truncatus	42.14	2.00e-66	245.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence