iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004148

Ensembl Protein ID

ENSAPLP00000011670.1

UniProt Accession

U3IWP4; U3IWP4_ANAPL

Genbank Protein ID

ENSAPLP00000011670

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01064991

Gene Name

CBLB

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000011898.1	ENSAPLT00000012399.1	ENSAPLP00000011670.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.60e-08	32.5	362	401

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl +w    ++s ++  CP Cr
   Q: 362  CKICAENDKD-VKIEPCGHLMCTSCLTAW----QESDGQ-GCPFCR 401
           99********.******************....555555.5****8 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

QNGRNPRKGR ILGFIDAIQD AVGPPSSSRP DRRTVEKTWK LMDKVVRLCQ NPKLQLKNSP 60
PYILDILPDT YQHLRLILSK YDDNQKLAQL SENEYFKIYI DSLMKKSKRA IRLFKEGKER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAACGGCC GCAACCCGCG CAAGGGACGG ATCCTGGGCT TCATCGACGC CATCCAAGAT 60
GCTGTGGGGC CCCCCAGCAG CAGCCGCCCC GACCGCAGGA CTGTGGAGAA GACCTGGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR009060--UBA-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING
SM00165--UBA

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001412	Ailuropoda melanoleuca	86.53	0.00e+00	1469.00
IUUC-Aca-005204	Anolis carolinensis	84.17	0.00e+00	1481.00
IUUC-Ame-011919	Astyanax mexicanus	64.68	0.00e+00	1043.00
IUUC-Bta-013044	Bos taurus	86.74	0.00e+00	1465.00
IUUC-Cel-018674	Caenorhabditis elegans	56.17	7.00e-134	470.00
IUUC-Cja-018813	Callithrix jacchus	78.97	0.00e+00	1348.00
IUUC-Cfa-021054	Canis familiaris	86.32	0.00e+00	1525.00
IUUC-Cpo-022514	Cavia porcellus	81.87	0.00e+00	1472.00
IUUC-Csa-024110	Chlorocebus sabaeus	86.22	0.00e+00	1483.00
IUUC-Cho-024886	Choloepus hoffmanni	69.66	0.00e+00	996.00
IUUC-Cin-025574	Ciona intestinalis	68.38	8.00e-174	602.00
IUUC-Dre-027480	Danio rerio	64.73	0.00e+00	1038.00
IUUC-Dno-028923	Dasypus novemcinctus	86.11	0.00e+00	1459.00
IUUC-Dor-031040	Dipodomys ordii	86.61	0.00e+00	784.00
IUUC-Dme-032213	Drosophila melanogaster	73.35	0.00e+00	640.00
IUUC-Ete-032406	Echinops telfairi	83.76	0.00e+00	1358.00
IUUC-Eca-033849	Equus caballus	86.01	0.00e+00	1492.00
IUUC-Fca-036224	Felis catus	86.54	0.00e+00	1497.00
IUUC-Fal-036860	Ficedula albicollis	98.66	0.00e+00	1030.00
IUUC-Gga-040159	Gallus gallus	90.81	0.00e+00	1605.00
IUUC-Gac-042312	Gasterosteus aculeatus	83.78	0.00e+00	878.00
IUUC-Ggo-045175	Gorilla gorilla	79.21	0.00e+00	1353.00
IUUC-Hsa-046306	Homo sapiens	86.32	0.00e+00	1484.00
IUUC-Lch-049931	Latimeria chalumnae	63.00	0.00e+00	908.00
IUUC-Loc-052524	Lepisosteus oculatus	69.14	0.00e+00	1085.00
IUUC-Laf-053635	Loxodonta africana	83.73	0.00e+00	1422.00
IUUC-Mcc-055536	Macaca mulatta	86.32	0.00e+00	1485.00
IUUC-Meu-056045	Macropus eugenii	74.61	0.00e+00	1202.00
IUUC-Mga-060177	Meleagris gallopavo	98.41	0.00e+00	1183.00
IUUC-Mmr-061088	Microcebus murinus	86.53	0.00e+00	1494.00
IUUC-Mdo-062020	Monodelphis domestica	87.05	0.00e+00	1487.00
IUUC-Mmu-063114	Mus musculus	82.29	0.00e+00	1436.00
IUUC-Mpu-066632	Mustela putorius furo	87.15	0.00e+00	1526.00
IUUC-Mlu-067145	Myotis lucifugus	86.22	0.00e+00	1487.00
IUUC-Ont-072323	Oreochromis niloticus	72.75	0.00e+00	887.00
IUUC-Oan-073165	Ornithorhynchus anatinus	87.07	0.00e+00	1561.00
IUUC-Ocu-074723	Oryctolagus cuniculus	86.42	0.00e+00	1500.00
IUUC-Oga-088021	Otolemur garnettii	85.18	0.00e+00	1473.00
IUUC-Oar-089809	Ovis aries	86.63	0.00e+00	1470.00
IUUC-Ptr-090834	Pan troglodytes	86.22	0.00e+00	1481.00
IUUC-Pan-092225	Papio anubis	86.32	0.00e+00	1488.00
IUUC-Psi-093317	Pelodiscus sinensis	89.58	0.00e+00	1626.00
IUUC-Pma-094249	Petromyzon marinus	77.24	4.00e-126	443.00
IUUC-Pab-097595	Pongo abelii	86.32	0.00e+00	1483.00
IUUC-Pca-100844	Procavia capensis	71.30	0.00e+00	1152.00
IUUC-Pva-103216	Pteropus vampyrus	80.04	0.00e+00	1409.00
IUUC-Rno-105381	Rattus norvegicus	84.66	0.00e+00	1493.00
IUUC-Sha-107574	Sarcophilus harrisii	86.26	0.00e+00	1474.00
IUUC-Sar-113500	Sorex araneus	76.17	0.00e+00	1229.00
IUUC-Ssc-115856	Sus scrofa	85.36	0.00e+00	1269.00
IUUC-Tgu-116866	Taeniopygia guttata	91.93	0.00e+00	1627.00
IUUC-Tru-118579	Takifugu rubripes	85.39	0.00e+00	879.00
IUUC-Tsy-119167	Tarsius syrichta	82.95	0.00e+00	1021.00
IUUC-Tni-120788	Tetraodon nigroviridis	85.09	0.00e+00	890.00
IUUC-Tbe-127830	Tupaia belangeri	88.85	0.00e+00	1101.00
IUUC-Ttr-128631	Tursiops truncatus	86.94	0.00e+00	1499.00
IUUC-Vpa-130713	Vicugna pacos	85.94	0.00e+00	1300.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence