iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAF	dbPTM	Phospho.ELM	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.50e-33	113.7	406	543

Active Site

Position(s)	Description	Evidence
495	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdpp....egisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.....ifhPnvyenGkvClsilk.....e 88
           R++kel+++++  p    ++i   + de  ++ ++vli Gp+dtpY++g+F+++i fp+ YPf+PPk+ flt+     +f+Pn+y++Gk+Clsil+     +
   Q: 406  RIAKELASIANALPlnasNSIY-VCYDEGRVDIIKVLISGPDDTPYANGLFEFDIFFPTGYPFSPPKCAFLTTgsgnvRFNPNLYNDGKICLSILGtwegrP 506
           8899999998888855534444.4555557*****************************************************************6677779 PP
   S: 89   eekWspalsvesvllsiqsll..aepnpesplneeaa 123
           eekW+p  s+ +vl+siq l+  ++p++++p  e+ +
   Q: 507  EEKWNPYCSLMQVLVSIQGLIfvKDPYFNEPGFERYQ 543
           ********************9999*******998875 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MSSQASQRSS STSAVAQKTR ERRKSKSRRR CWFGCLWLSS RVSLIRSSSR FSRSPEPDES 60
LTAIDKVMSI INEKPLKMAH ILKTARFVND VSFSERKQFV ECGVIHHLLE LIGETAISDF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGTTTGTTA CAGGTAGTTC CTCGAGCCTG GGTGGATTCA TATTTGAAAC CATGTCTTCG 60
CAAGCATCTC AACGCTCATC AAGCACAAGT GCTGTCGCAC AAAAAACTCG CGAACGGCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0009966--P:regulation of signal transduction

KEGG

cel:CELE_B0403.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001098	Aegilops tauschii	38.03	9.00e-41	159.00
IUUC-Aml-001583	Ailuropoda melanoleuca	56.77	6.00e-57	217.00
IUUC-Atr-002598	Amborella trichopoda	38.40	2.00e-41	161.00
IUUC-Apl-004144	Anas platyrhynchos	56.48	4.00e-57	217.00
IUUC-Aca-005257	Anolis carolinensis	52.00	2.00e-57	218.00
IUUC-Aly-005605	Arabidopsis lyrata	39.71	1.00e-40	159.00
IUUC-Ath-007217	Arabidopsis thaliana	42.51	7.00e-40	157.00
IUUC-Acl-008031	Aspergillus clavatus	45.81	5.00e-32	132.00
IUUC-Afl-008480	Aspergillus flavus	37.77	3.00e-29	123.00
IUUC-Afu-009040	Aspergillus fumigatus	40.98	1.00e-31	131.00
IUUC-Ani-009463	Aspergillus nidulans	43.45	5.00e-33	134.00
IUUC-Ang-009816	Aspergillus niger	40.44	6.00e-30	125.00
IUUC-Aor-010121	Aspergillus oryzae	44.03	4.00e-26	112.00
IUUC-Ate-010487	Aspergillus terreus	39.67	9.00e-32	131.00
IUUC-Ame-011337	Astyanax mexicanus	56.77	6.00e-57	217.00
IUUC-Bta-012501	Bos taurus	56.77	7.00e-57	216.00
IUUC-Bci-013596	Botrytis cinerea	38.82	8.00e-25	107.00
IUUC-Bdi-014262	Brachypodium distachyon	42.31	3.00e-39	154.00
IUUC-Bol-015976	Brassica oleracea	40.29	3.00e-41	161.00
IUUC-Bra-016646	Brassica rapa	39.08	1.00e-42	166.00
IUUC-Cja-018746	Callithrix jacchus	56.77	1.00e-56	216.00
IUUC-Cfa-020170	Canis familiaris	56.77	5.00e-57	217.00
IUUC-Cpo-022138	Cavia porcellus	56.77	3.00e-57	217.00
IUUC-Cre-022768	Chlamydomonas reinhardtii	42.55	8.00e-43	165.00
IUUC-Csa-023927	Chlorocebus sabaeus	56.77	6.00e-57	217.00
IUUC-Cho-024890	Choloepus hoffmanni	57.30	2.00e-52	202.00
IUUC-Cgl-026412	Colletotrichum gloeosporioides	38.95	1.00e-25	109.00
IUUC-Cne-026995	Cryptococcus neoformans	37.69	5.00e-36	145.00
IUUC-Dre-027941	Danio rerio	34.65	1.00e-73	272.00
IUUC-Dno-028913	Dasypus novemcinctus	56.77	5.00e-57	217.00
IUUC-Dor-030715	Dipodomys ordii	45.76	1.00e-37	152.00
IUUC-Dse-031232	Dothistroma septosporum	41.83	2.00e-40	159.00
IUUC-Dme-031592	Drosophila melanogaster	38.11	5.00e-65	243.00
IUUC-Ete-032587	Echinops telfairi	55.21	1.00e-52	202.00
IUUC-Eca-033819	Equus caballus	56.25	5.00e-55	211.00
IUUC-Eeu-034863	Erinaceus europaeus	50.32	4.00e-34	141.00
IUUC-Fca-035505	Felis catus	56.77	7.00e-57	216.00
IUUC-Fal-037318	Ficedula albicollis	56.77	5.00e-57	217.00
IUUC-Fox-037961	Fusarium oxysporum	39.05	8.00e-25	106.00
IUUC-Fso-038352	Fusarium solani	37.28	6.00e-22	97.40
IUUC-Gmo-039521	Gadus morhua	55.21	6.00e-56	211.00
IUUC-Ggr-040040	Gaeumannomyces graminis	41.97	6.00e-34	138.00
IUUC-Gga-040728	Gallus gallus	56.77	6.00e-57	217.00
IUUC-Gac-042251	Gasterosteus aculeatus	33.10	1.00e-67	250.00
IUUC-Gma-044076	Glycine max	36.08	1.00e-40	160.00
IUUC-Ggo-045316	Gorilla gorilla	40.57	6.00e-40	158.00
IUUC-Hsa-046339	Homo sapiens	56.77	6.00e-57	217.00
IUUC-Hvu-047795	Hordeum vulgare	37.19	1.00e-39	155.00
IUUC-Itr-048048	Ictidomys tridecemlineatus	39.73	1.00e-39	157.00
IUUC-Lch-050164	Latimeria chalumnae	34.55	1.00e-67	252.00
IUUC-Lpe-050857	Leersia perrieri	37.45	1.00e-38	152.00
IUUC-Loc-052800	Lepisosteus oculatus	56.77	4.00e-57	218.00
IUUC-Lma-053044	Leptosphaeria maculans	40.00	8.00e-29	120.00
IUUC-Laf-054034	Loxodonta africana	56.77	6.00e-57	217.00
IUUC-Mcc-055267	Macaca mulatta	56.77	7.00e-57	216.00
IUUC-Meu-056834	Macropus eugenii	40.00	1.00e-39	157.00
IUUC-Mor-057074	Magnaporthe oryzae	37.65	3.00e-21	95.10
IUUC-Mpo-057396	Magnaporthe poae	43.50	2.00e-32	133.00
IUUC-Mtr-057685	Medicago truncatula	38.54	8.00e-39	152.00
IUUC-Mla-059114	Melampsora laricipopulina	34.80	4.00e-36	145.00
IUUC-Mga-059594	Meleagris gallopavo	66.33	1.00e-35	146.00
IUUC-Mvi-060389	Microbotryum violaceum	33.74	7.00e-30	124.00
IUUC-Mmr-061179	Microcebus murinus	56.77	6.00e-57	217.00
IUUC-Mdo-062990	Monodelphis domestica	56.77	7.00e-57	217.00
IUUC-Mmu-063825	Mus musculus	36.40	6.00e-68	253.00
IUUC-Mac-064881	Musa acuminata	41.26	8.00e-40	156.00
IUUC-Mpu-065908	Mustela putorius furo	56.77	5.00e-57	217.00
IUUC-Mlu-067106	Myotis lucifugus	56.77	6.00e-57	217.00
IUUC-Nfi-068366	Neosartorya fischeri	36.44	7.00e-32	131.00
IUUC-Ncr-068852	Neurospora crassa	37.33	1.00e-17	83.20
IUUC-Nle-069347	Nomascus leucogenys	56.77	7.00e-57	216.00
IUUC-Opr-070799	Ochotona princeps	56.77	7.00e-57	216.00
IUUC-Ont-072046	Oreochromis niloticus	34.32	9.00e-70	259.00
IUUC-Oan-073328	Ornithorhynchus anatinus	41.89	4.00e-26	109.00
IUUC-Ocu-074556	Oryctolagus cuniculus	36.33	6.00e-66	247.00
IUUC-Oba-075900	Oryza barthii	42.23	2.00e-39	155.00
IUUC-Obr-076484	Oryza brachyantha	38.46	2.00e-39	155.00
IUUC-Ogl-077514	Oryza glaberrima	42.03	1.00e-39	156.00
IUUC-Ogu-078900	Oryza glumaepatula	42.31	9.00e-41	159.00
IUUC-Oin-080044	Oryza indica	42.23	3.00e-39	155.00
IUUC-Olo-080341	Oryza longistaminata	41.75	4.00e-40	159.00
IUUC-Ome-081962	Oryza meridionalis	42.23	2.00e-39	154.00
IUUC-Oni-082462	Oryza nivara	42.23	2.00e-39	154.00
IUUC-Opu-083150	Oryza punctata	41.35	2.00e-39	155.00
IUUC-Oru-085281	Oryza rufipogon	42.23	2.00e-39	154.00
IUUC-Osa-085726	Oryza sativa	42.23	2.00e-39	155.00
IUUC-Ola-087459	Oryzias latipes	33.39	5.00e-74	272.00
IUUC-Oga-088251	Otolemur garnettii	48.07	6.00e-40	160.00
IUUC-Oar-090367	Ovis aries	56.77	6.00e-57	217.00
IUUC-Ptr-091512	Pan troglodytes	56.77	7.00e-57	216.00
IUUC-Pan-092222	Papio anubis	35.10	3.00e-67	251.00
IUUC-Psi-093231	Pelodiscus sinensis	44.97	7.00e-37	148.00
IUUC-Pma-094499	Petromyzon marinus	43.59	2.00e-38	153.00
IUUC-Pno-095065	Phaeosphaeria nodorum	40.72	1.00e-28	120.00
IUUC-Ppa-095592	Physcomitrella patens	31.85	2.00e-59	223.00
IUUC-Pfo-097086	Poecilia formosa	35.33	4.00e-68	254.00
IUUC-Pab-098390	Pongo abelii	56.77	6.00e-57	217.00
IUUC-Pop-099782	Populus trichocarpa	41.38	4.00e-41	161.00
IUUC-Pca-101036	Procavia capensis	48.41	1.00e-29	126.00
IUUC-Ppe-101722	Prunus persica	41.55	7.00e-41	160.00
IUUC-Pva-103053	Pteropus vampyrus	56.77	6.00e-57	217.00
IUUC-Pte-104333	Pyrenophora teres	30.02	8.00e-45	175.00
IUUC-Pyt-104498	Pyrenophora triticirepentis	42.50	7.00e-42	164.00
IUUC-Rno-105947	Rattus norvegicus	40.00	1.00e-40	160.00
IUUC-Sha-107483	Sarcophilus harrisii	47.23	4.00e-57	218.00
IUUC-Smo-108915	Selaginella moellendorffii	49.25	2.00e-44	171.00
IUUC-Sit-110087	Setaria italica	41.06	5.00e-40	157.00
IUUC-Sly-110929	Solanum lycopersicum	40.78	3.00e-41	162.00
IUUC-Stu-112554	Solanum tuberosum	40.98	5.00e-41	161.00
IUUC-Sar-113102	Sorex araneus	42.74	3.00e-22	97.80
IUUC-Sbi-114054	Sorghum bicolor	41.12	3.00e-41	161.00
IUUC-Sre-114954	Sporisorium reilianum	43.79	3.00e-33	135.00
IUUC-Ssc-115927	Sus scrofa	56.77	3.00e-57	217.00
IUUC-Tgu-117132	Taeniopygia guttata	56.48	8.00e-57	216.00
IUUC-Tru-118115	Takifugu rubripes	49.81	6.00e-60	227.00
IUUC-Tsy-118899	Tarsius syrichta	62.18	2.00e-48	189.00
IUUC-Tni-120634	Tetraodon nigroviridis	34.09	9.00e-65	242.00
IUUC-Tca-121636	Theobroma cacao	40.58	3.00e-41	162.00
IUUC-Tre-121946	Trichoderma reesei	37.06	2.00e-22	98.60
IUUC-Tvi-122513	Trichoderma virens	37.65	1.00e-25	109.00
IUUC-Tae-125708	Triticum aestivum	37.87	7.00e-41	160.00
IUUC-Tur-126255	Triticum urartu	37.87	1.00e-40	159.00
IUUC-Tme-126930	Tuber melanosporum	38.27	8.00e-45	174.00
IUUC-Tbe-127630	Tupaia belangeri	48.31	1.00e-18	90.10
IUUC-Ttr-128629	Tursiops truncatus	34.63	2.00e-65	244.00
IUUC-Uma-129323	Ustilago maydis	45.10	2.00e-34	139.00
IUUC-Vda-129728	Verticillium dahliae	38.67	2.00e-19	89.00
IUUC-Vpa-130310	Vicugna pacos	56.77	6.00e-57	217.00
IUUC-Vvi-131664	Vitis vinifera	36.52	2.00e-32	132.00
IUUC-Xtr-131861	Xenopus tropicalis	58.03	8.00e-64	239.00
IUUC-Xma-133613	Xiphophorus maculatus	32.93	2.00e-67	252.00
IUUC-Zma-134696	Zea mays	41.12	5.00e-41	160.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence