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Basic Information Integrated Annotations

Tag Content
UUCD2 ID IUUC-Ath-006674
Ensembl Protein ID AT1G79650.4
UniProt Accession Q84L33; Q84L34; Q8LA46; Q94CE9; Q9MA10; RD23B_ARATH
Genbank Protein ID BAC76389.1; BAC76390.1; AAF68123.1; AEE36279.1; AEE36281.1; AAK59419.1; AAL34277.1; AAM65583.1
Protein Name Ubiquitin receptor RAD23b; Putative DNA repair protein RAD23-1; RAD23-like protein 1
Genbank Nucleotide ID AB109193; AB109194; AC010793; CP002684; CP002684; AY034912; AY063103; AY088037
Gene Name RAD23B; RAD23; RAD23-1; At1g79650; F20B17.8
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT1G79650 AT1G79650.4 AT1G79650.4
AT1G79650 AT1G79650.3 AT1G79650.3
AT1G79650 AT1G79650.1 AT1G79650.1
AT1G79650 AT1G79650.2 AT1G79650.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
Mentha
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
UBD/Alpha-Helix/UBA UBA 20059542; 20086187
ULD/UDP/UFD/MUB MUB 20086187; 25320573
Classification
Family E-value Score Start End
UBD/Alpha-Helix/UBA 1.00e-25 90.0 171 213
ULD/UDP/UBQ/UBQ_PIM 7.80e-23 81.1 1 79
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMG...FdreealqaLraannnleaAveyLldg 41
    ++e++++q++eMG +d+e++ +aLraa+nn+e+Av+yL++g
   Q: 171 SLEQMVQQIMEMGggsWDKETVTRALRAAYNNPERAVDYLYSG 213
    679*************************************986 PP
   


   ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesg...vppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksks 76
    mkltvktlkg++fe++v ++dt+ ++K++i++++g +p+ qq LI++Gk+LkD+t+L e+++ ++ +++++++ksks
   Q: 1 MKLTVKTLKGSHFEIRVLPSDTIMAVKKNIEDSQGkdnYPCGQQLLIHNGKVLKDETSLVENKVTEEGFLVVMLSKSKS 79
    99**************************************************************************986 PP
   

Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description



     May be involved in nucleotide excision repair (By similarity). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP).
May be involved in nucleotide excision repair (By similarity). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP).
Protein Sequence
(Fasta)
MKLTVKTLKG SHFEIRVLPS DTIMAVKKNI EDSQGKDNYP CGQQLLIHNG KVLKDETSLV 60
ENKVTEEGFL VVMLSKSKSG GSAGQASVQT SSVSQPVSAT TSSTKPAAPS TTQSSPVPAS 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Ath-006674|UBD,UBA;ULD,MUB;ULD,UBQ_PIM|Arabidopsis thaliana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCTAGAGAGA GAGACTGTTT TAGCTACGGT CAGCTTTTCT CTAGCGTCGG GGCCTCGATC 60
TCTTGATTTG AGCTTTTCTT AGGTCTGTCT CTCTCTGTAC ACTCTCTCCG CCGTCGTATC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Ath-006674|UBD,UBA;ULD,MUB;ULD,UBQ_PIM|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0227--DNA damage
KW-0234--DNA repair
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR004806--Rad23
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR015360--XPC-bd

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin
PF09280--XPC-binding

PRINTS

PR01839--RAD23PROTEIN

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0031593--F:polyubiquitin binding
GO:0070628--F:proteasome binding
GO:0006289--P:nucleotide-excision repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

KEGG ath:AT1G79650
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Atr-002756 Amborella trichopoda 60.69 3.00e-127 447.00
IUUC-Aca-004704 Anolis carolinensis 35.59 2.00e-43 169.00
IUUC-Aly-006159 Arabidopsis lyrata 84.05 2.00e-176 610.00
IUUC-Afu-008877 Aspergillus fumigatus 38.49 6.00e-31 127.00
IUUC-Bol-016300 Brassica oleracea 77.97 1.00e-151 528.00
IUUC-Bra-016952 Brassica rapa 77.97 2.00e-146 511.00
IUUC-Cja-018772 Callithrix jacchus 40.74 7.00e-32 130.00
IUUC-Cne-027056 Cryptococcus neoformans 39.13 4.00e-13 68.60
IUUC-Cme-027260 Cyanidioschyzon merolae 30.19 4.00e-31 128.00
IUUC-Dre-028369 Danio rerio 38.68 1.00e-39 156.00
IUUC-Dno-029543 Dasypus novemcinctus 40.74 3.00e-33 135.00
IUUC-Dme-032027 Drosophila melanogaster 29.40 6.00e-43 167.00
IUUC-Fca-035679 Felis catus 40.57 2.00e-31 129.00
IUUC-Fox-037960 Fusarium oxysporum 49.62 1.00e-21 96.70
IUUC-Gmo-039080 Gadus morhua 37.29 4.00e-30 124.00
IUUC-Gac-042239 Gasterosteus aculeatus 34.80 9.00e-44 170.00
IUUC-Gma-044245 Glycine max 68.86 4.00e-147 513.00
IUUC-Itr-048295 Ictidomys tridecemlineatus 39.75 3.00e-29 122.00
IUUC-Loc-051748 Lepisosteus oculatus 40.00 2.00e-33 135.00
IUUC-Meu-056459 Macropus eugenii 44.17 7.00e-38 150.00
IUUC-Mtr-058239 Medicago truncatula 64.50 3.00e-131 461.00
IUUC-Mla-058961 Melampsora laricipopulina 44.60 5.00e-25 108.00
IUUC-Mdo-062742 Monodelphis domestica 37.95 2.00e-55 208.00
IUUC-Mac-064468 Musa acuminata 62.87 1.00e-126 445.00
IUUC-Mpu-066389 Mustela putorius furo 39.84 7.00e-30 124.00
IUUC-Nfi-068390 Neosartorya fischeri 38.49 6.00e-31 127.00
IUUC-Opr-070234 Ochotona princeps 46.43 1.00e-09 57.00
IUUC-Oan-073572 Ornithorhynchus anatinus 37.25 1.00e-47 183.00
IUUC-Ocu-074831 Oryctolagus cuniculus 39.75 2.00e-32 132.00
IUUC-Ola-086540 Oryzias latipes 36.00 6.00e-32 130.00
IUUC-Oga-088023 Otolemur garnettii 40.24 5.00e-33 134.00
IUUC-Pan-092140 Papio anubis 35.57 4.00e-48 184.00
IUUC-Pno-095064 Phaeosphaeria nodorum 47.37 2.00e-14 72.40
IUUC-Pfo-097385 Poecilia formosa 40.40 4.00e-39 154.00
IUUC-Pab-097868 Pongo abelii 40.24 2.00e-32 132.00
IUUC-Ppe-101522 Prunus persica 68.98 1.00e-146 511.00
IUUC-Sha-106918 Sarcophilus harrisii 37.53 2.00e-45 176.00
IUUC-Smo-109129 Selaginella moellendorffii 53.19 1.00e-96 345.00
IUUC-Sbi-114459 Sorghum bicolor 60.45 8.00e-119 419.00
IUUC-Tme-127092 Tuber melanosporum 47.45 4.00e-23 101.00
IUUC-Vpa-130357 Vicugna pacos 37.02 1.00e-16 79.70
IUUC-Xma-133503 Xiphophorus maculatus 34.95 9.00e-48 183.00
Created Date 25-Jun-2017

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