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Tag Content
UUCD2 ID IUUC-Bta-012728
UUCD1 version UUC-BoT-00962
Ensembl Protein ID ENSBTAP00000024336.3
UniProt Accession Q3T0W3; RN181_BOVIN
Genbank Protein ID AAI02231.1
Protein Name E3 ubiquitin-protein ligase RNF181; RING finger protein 181; RING-type E3 ubiquitin transferase RNF181
Genbank Nucleotide ID BC102230
Gene Name RNF181
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000018286.3 ENSBTAT00000024336.3 ENSBTAP00000024336.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 2.30e-09 37.8 76 117
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cl +f+++   + +pC H+fh +C+  w       sk+ +CPlCr
   Q: 76   CPVCLLEFEEEetAIEMPCHHLFHSNCILPW------LSKTNSCPLCR 117
           ******9*44444667***************......**********8 PP
   
Organism Bos taurus
Functional Description
(View)

Functional Description


     E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
 E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Protein Sequence
(Fasta)
MASYFDEHDC EPLDRERDPR TNMLLELARS LFNRMDFEDL GLVVDWDHHL PPPAAKTAVE 60
NLPRTVIRGS QAELKCPVCL LEFEEEETAI EMPCHHLFHS NCILPWLSKT NSCPLCRHEL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-012728|E3,RING|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACGGCCGGGG TCTGAGGGCT GTGTCAGACA GCCCGGCTGC CATGGCGTCC TATTTCGATG 60
AACACGACTG CGAGCCGTTG GATCGCGAAC GGGATCCTCG AACAAACATG CTGCTGGAGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-012728|E3,RING|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF13639--zf-RING_2
SMART

SM00184--RING
Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG bta:515743
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002024 Ailuropoda melanoleuca 91.77 2.00e-78 284.00
IUUC-Atr-002553 Amborella trichopoda 49.41 5.00e-18 85.90
IUUC-Ame-011175 Astyanax mexicanus 64.10 3.00e-48 183.00
IUUC-Bol-015156 Brassica oleracea 51.22 2.00e-19 90.50
IUUC-Bra-017773 Brassica rapa 48.78 3.00e-18 86.70
IUUC-Cja-019559 Callithrix jacchus 94.77 3.00e-80 290.00
IUUC-Cfa-020880 Canis familiaris 92.81 1.00e-78 284.00
IUUC-Cpo-022238 Cavia porcellus 77.38 3.00e-67 247.00
IUUC-Csa-023787 Chlorocebus sabaeus 93.46 6.00e-79 285.00
IUUC-Cin-025410 Ciona intestinalis 50.49 1.00e-19 88.60
IUUC-Dre-028637 Danio rerio 63.46 1.00e-50 191.00
IUUC-Dno-029183 Dasypus novemcinctus 93.46 8.00e-79 285.00
IUUC-Dor-030499 Dipodomys ordii 88.24 4.00e-73 266.00
IUUC-Dme-031824 Drosophila melanogaster 37.18 1.00e-16 78.60
IUUC-Ete-032501 Echinops telfairi 92.74 2.00e-63 233.00
IUUC-Eca-033768 Equus caballus 95.42 1.00e-80 291.00
IUUC-Eeu-035209 Erinaceus europaeus 93.33 7.00e-68 248.00
IUUC-Fca-036074 Felis catus 89.87 7.00e-77 278.00
IUUC-Gmo-038882 Gadus morhua 63.29 6.00e-44 169.00
IUUC-Gac-042217 Gasterosteus aculeatus 65.41 2.00e-51 194.00
IUUC-Gma-044323 Glycine max 52.94 2.00e-21 97.10
IUUC-Ggo-044890 Gorilla gorilla 94.12 2.00e-79 287.00
IUUC-Hsa-045980 Homo sapiens 93.46 4.00e-79 286.00
IUUC-Itr-048618 Ictidomys tridecemlineatus 92.81 1.00e-79 287.00
IUUC-Lch-049758 Latimeria chalumnae 66.24 1.00e-51 195.00
IUUC-Lpe-051546 Leersia perrieri 47.62 2.00e-19 91.70
IUUC-Loc-052244 Lepisosteus oculatus 62.11 5.00e-50 189.00
IUUC-Laf-054225 Loxodonta africana 85.54 5.00e-76 276.00
IUUC-Meu-056718 Macropus eugenii 69.48 2.00e-58 217.00
IUUC-Mtr-058205 Medicago truncatula 44.79 7.00e-17 82.00
IUUC-Mmr-061195 Microcebus murinus 92.16 1.00e-77 281.00
IUUC-Mdo-062131 Monodelphis domestica 65.09 2.00e-56 210.00
IUUC-Mmu-063803 Mus musculus 73.77 5.00e-44 170.00
IUUC-Mac-065049 Musa acuminata 46.81 1.00e-18 86.30
IUUC-Mpu-066689 Mustela putorius furo 93.38 6.00e-70 255.00
IUUC-Mlu-067441 Myotis lucifugus 80.24 1.00e-70 258.00
IUUC-Nle-069091 Nomascus leucogenys 90.13 9.00e-76 275.00
IUUC-Opr-070653 Ochotona princeps 92.16 2.00e-78 283.00
IUUC-Ont-071833 Oreochromis niloticus 64.33 1.00e-50 192.00
IUUC-Oan-073246 Ornithorhynchus anatinus 71.34 3.00e-56 210.00
IUUC-Ocu-074317 Oryctolagus cuniculus 92.16 5.00e-78 282.00
IUUC-Oba-075271 Oryza barthii 41.86 9.00e-13 67.00
IUUC-Obr-076852 Oryza brachyantha 51.19 8.00e-19 89.70
IUUC-Ogl-077246 Oryza glaberrima 52.05 4.00e-17 82.00
IUUC-Ogu-078441 Oryza glumaepatula 50.00 3.00e-20 93.60
IUUC-Oin-079290 Oryza indica 50.00 1.00e-20 92.80
IUUC-Olo-080680 Oryza longistaminata 50.00 4.00e-20 92.80
IUUC-Oni-082704 Oryza nivara 50.00 6.00e-20 92.00
IUUC-Opu-083695 Oryza punctata 52.50 2.00e-19 92.00
IUUC-Oru-084216 Oryza rufipogon 50.00 2.00e-20 93.60
IUUC-Osa-086033 Oryza sativa 50.00 2.00e-20 93.60
IUUC-Ola-087215 Oryzias latipes 64.33 8.00e-48 182.00
IUUC-Oga-088998 Otolemur garnettii 77.71 3.00e-57 213.00
IUUC-Oar-089622 Ovis aries 99.35 4.00e-88 316.00
IUUC-Ptr-091537 Pan troglodytes 94.12 2.00e-79 287.00
IUUC-Pan-091865 Papio anubis 94.12 2.00e-79 287.00
IUUC-Pfo-097473 Poecilia formosa 67.52 6.00e-53 199.00
IUUC-Pab-097986 Pongo abelii 94.12 2.00e-79 287.00
IUUC-Pop-100030 Populus trichocarpa 54.79 5.00e-18 85.90
IUUC-Pca-100492 Procavia capensis 91.50 2.00e-77 280.00
IUUC-Ppe-101517 Prunus persica 35.86 9.00e-19 87.80
IUUC-Pva-102641 Pteropus vampyrus 94.12 1.00e-79 288.00
IUUC-Rno-105300 Rattus norvegicus 81.93 1.00e-71 261.00
IUUC-Sha-106578 Sarcophilus harrisii 67.68 4.00e-52 196.00
IUUC-Sit-110240 Setaria italica 50.50 8.00e-22 99.40
IUUC-Stu-112415 Solanum tuberosum 47.50 1.00e-18 87.80
IUUC-Sar-112952 Sorex araneus 89.09 2.00e-50 189.00
IUUC-Sbi-114270 Sorghum bicolor 53.41 5.00e-19 88.20
IUUC-Ssc-115694 Sus scrofa 96.08 2.00e-80 290.00
IUUC-Tsy-119580 Tarsius syrichta 92.50 3.00e-36 142.00
IUUC-Tni-120075 Tetraodon nigroviridis 66.24 6.00e-52 196.00
IUUC-Tca-121683 Theobroma cacao 46.43 1.00e-18 87.80
IUUC-Tae-124824 Triticum aestivum 48.81 6.00e-18 85.50
IUUC-Tur-126513 Triticum urartu 48.81 6.00e-18 85.50
IUUC-Ttr-129081 Tursiops truncatus 96.08 5.00e-81 292.00
IUUC-Vpa-130305 Vicugna pacos 94.26 6.00e-58 215.00
IUUC-Xtr-132897 Xenopus tropicalis 60.71 7.00e-41 159.00
IUUC-Xma-133809 Xiphophorus maculatus 67.52 6.00e-53 199.00
Created Date 25-Jun-2017

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