iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023352

Ensembl Protein ID

ENSCSAP00000004683.1

UniProt Accession

A0A0D9R7U4; A0A0D9R7U4_CHLSB

Genbank Protein ID

ENSCSAP00000004683

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01145896

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000008437.1	ENSCSAT00000006480.1	ENSCSAP00000004683.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-35	119.6	46	83
UBD/Beta-Prp	4.00e-55	187.0	148	405

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 46   GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 83
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++++++++dgt+  w+++ ++l      l+  ++  ++v+ ++  fs  g +l+tgs+D++i+ +   +++++ +  l+ h+d+v s+
   Q: 148  QRYMVSTGADGTVCFWQWDLESLkfsprpLKFTEKPRPGVQMLCssFSVGGMFLATGSTDHVIRMYflGFEAPEKIAELESHTDKVDSI 236
           689*****************99999988777778888888755522888888**************99999****************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +f+ +gd+++sGs+d t+r+w  e+ ++ +                 ++  +  v++++++++++++v++ +D ++++W++ tg+ll+ 
   Q: 237  QFCNNGDRFLSGSRDGTARIWRFEQLEWRSIlldmatrisgdlsseEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHN 325
           **************************99998999********998877777888*********************************** PP
   S: 175  ltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l g h d v  l+   fds  + ++s+++dg++ +wd+ +g+ ++ + +         v + +fs+++++++++ s+g + i+
   Q: 326  LLG-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDITKGTKMKHYFNMIegqghGAVFDCKFSQDGQHFACTDSHGHLLIF 405
           **9.*********555555..99****************999977766544444456677789999*****999999998886 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MPVNYGSPPN LVEIHRGKQL TGCSTFSTAF PGTMYQHIKM HRRILGHLSA VYCVAFDRTG 60
HRIFTGSDDC LVKIWSTHNG RLLSTLRGHS AEISDMAVNY ENTMIAAGSC DKIIRVWCLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCAGTGA ATTATGGTTC CCCACCAAAT CTTGGTAAGT AAGGTTGGCC TTTGAGATGC 60
CTGAAATAAT TCTTTTTACA TTTCTCAACA ACCTTTATAA ATGCTGTATT AAAATTTAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002332	Ailuropoda melanoleuca	83.59	0.00e+00	3169.00
IUUC-Apl-004083	Anas platyrhynchos	69.40	0.00e+00	1831.00
IUUC-Aca-004348	Anolis carolinensis	72.60	0.00e+00	1956.00
IUUC-Bta-013217	Bos taurus	87.91	0.00e+00	3450.00
IUUC-Cja-019966	Callithrix jacchus	94.32	0.00e+00	3780.00
IUUC-Cfa-021037	Canis familiaris	87.59	0.00e+00	3365.00
IUUC-Cpo-021934	Cavia porcellus	91.22	0.00e+00	2532.00
IUUC-Cho-024690	Choloepus hoffmanni	79.35	0.00e+00	1365.00
IUUC-Dno-028938	Dasypus novemcinctus	85.88	0.00e+00	3383.00
IUUC-Dor-030444	Dipodomys ordii	75.96	0.00e+00	832.00
IUUC-Ete-032717	Echinops telfairi	72.64	0.00e+00	981.00
IUUC-Eca-034349	Equus caballus	88.86	0.00e+00	3403.00
IUUC-Fca-035485	Felis catus	81.68	0.00e+00	2967.00
IUUC-Fal-037307	Ficedula albicollis	69.44	0.00e+00	2198.00
IUUC-Ggo-045500	Gorilla gorilla	97.62	0.00e+00	3855.00
IUUC-Hsa-046350	Homo sapiens	97.62	0.00e+00	3853.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	95.07	0.00e+00	1170.00
IUUC-Lch-049662	Latimeria chalumnae	66.28	0.00e+00	1872.00
IUUC-Laf-053848	Loxodonta africana	86.52	0.00e+00	3326.00
IUUC-Mcc-054638	Macaca mulatta	99.31	0.00e+00	3920.00
IUUC-Meu-056739	Macropus eugenii	78.05	0.00e+00	972.00
IUUC-Mga-060165	Meleagris gallopavo	76.56	0.00e+00	2088.00
IUUC-Mmr-061227	Microcebus murinus	91.13	0.00e+00	3568.00
IUUC-Mdo-062074	Monodelphis domestica	82.44	0.00e+00	2237.00
IUUC-Mmu-064075	Mus musculus	81.92	0.00e+00	2778.00
IUUC-Mpu-066643	Mustela putorius furo	90.48	0.00e+00	2914.00
IUUC-Mlu-067735	Myotis lucifugus	85.72	0.00e+00	3348.00
IUUC-Nle-069402	Nomascus leucogenys	95.84	0.00e+00	2912.00
IUUC-Oan-072954	Ornithorhynchus anatinus	69.33	0.00e+00	2593.00
IUUC-Ocu-074456	Oryctolagus cuniculus	87.74	0.00e+00	3535.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.57	2.00e-56	214.00
IUUC-Oga-087938	Otolemur garnettii	84.48	0.00e+00	3091.00
IUUC-Oar-090214	Ovis aries	87.23	0.00e+00	3451.00
IUUC-Ptr-091213	Pan troglodytes	97.62	0.00e+00	3821.00
IUUC-Pan-092444	Papio anubis	98.99	0.00e+00	3888.00
IUUC-Psi-093271	Pelodiscus sinensis	60.55	0.00e+00	2229.00
IUUC-Pfo-097318	Poecilia formosa	62.53	0.00e+00	1623.00
IUUC-Pab-097573	Pongo abelii	96.24	0.00e+00	3749.00
IUUC-Pca-100759	Procavia capensis	70.24	0.00e+00	956.00
IUUC-Pva-102782	Pteropus vampyrus	87.51	0.00e+00	3446.00
IUUC-Rno-105687	Rattus norvegicus	77.97	0.00e+00	3076.00
IUUC-Sar-113519	Sorex araneus	80.54	0.00e+00	1781.00
IUUC-Tgu-116513	Taeniopygia guttata	76.56	0.00e+00	2102.00
IUUC-Tsy-118921	Tarsius syrichta	89.05	0.00e+00	1847.00
IUUC-Tbe-127663	Tupaia belangeri	79.09	0.00e+00	1343.00
IUUC-Ttr-128561	Tursiops truncatus	85.81	0.00e+00	3207.00
IUUC-Vpa-130444	Vicugna pacos	85.28	0.00e+00	3282.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence