iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044956

UUCD1 version

UUC-GoG-01096

Ensembl Protein ID

ENSGGOP00000011240.2

UniProt Accession

G3R7A9; G3R7A9_GORGO

Protein Name

Uncharacterized protein

Gene Name

USP32

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000011515.2	ENSGGOT00000011569.2	ENSGGOP00000011240.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.50e-82	276.1	682	1391

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln++np ++kg+++k++ +l++el ++++k+v+p +l  +++k+a++f+g
   Q: 682  TGLSNLGNTCFMNSSIQCVSNTQPLTQYFISgRHLYELNRTNPIGMKGHMAKCYGDLVREL-SGTQKSVAPLKLQWTIAKYAPRFNG 767
           7******************************9*****************************.************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a++++ ++n+s+++dlF+gql+sq+kc++c+++s+r++p
   Q: 768  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSD--GRPDWevaaeAWDNHLRRNRSIVVDLFHGQLRSQVKCKTCGHISVRFDP 852
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 853  FNFLSLPLPMDSYMHLEitvikldgttpvryglrlnmdekytglkkqlsdlcglnaeqillaevhgsniknfpqdnqkvrlsvsgfl 939
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 940  cafeipvpaspisassstqtmrtelyflssqknrpslfgmplivpctvhtrkkdlydavwiqvsrlasplppqeasnhaqdcddsmg 1026
           *************************************************************************************** PP
   S: 186  ...................................................................................slqd 189
                                                                                              +l++
   Q: 1027 yqypftlrvvqkdgnscawcpwyrfcrgckidcgedrafignayiavdwdptalhlryqtsqervvdehesveqsrraqaepiNLDS 1113
           *************************************************************************************** PP
   S: 190  cLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts........ 267
           cL++ft+eeel ++++yyc+kck ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+e +d s f++         
   Q: 1114 CLRAFTSEEELGENEMYYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNG--RWIKSQKIVKFPREsFDPSAFLVPrdpalcqr 1198
           ************************************************99775..5569****************999977777777 PP
   S: 268  ....................................................................................... 267
                                                                                                  
   Q: 1199 kpltpqgdelseprilarevkkvdaqssageedvllskspsslsanissspkgspsssrksgtscpssknsspnssprtlgrskgrl 1285
           777777777777777777777777777666666666666666666666666666666665555555555555444444444444444 PP
   S: 268  ...............peekqke................................................................. 274
                          +     +                                                                 
   Q: 1286 rlpqigsknklssskE-----Nldasrengagqiceladalsrghvlggsqpelvtpqdhevalangflyeheacgngysngqlgnh 1367
           4444444444444330.....033344444444444444444444444444444444444444444444444444444444444444 PP
   S: 275  ...............kkkYeLiav 283
                          k +Y+L+a+
   Q: 1368 seedstddqredtriKPIYNLYAI 1391
           444444555555556777777765 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MGAKESRIGF LSYEEALRRV TDVELKRLKD AFKRTRGLSY YMGQHCFIRE VLGDGVPPRV 60
AEVIYCSFGG TSKGLHFNNL IVGLVLLTRG KDEEKAKYTF SLFSSQSGNY IIREEMERML 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGTGCCA AGGAGTCACG GATCGGATTC CTCAGCTACG AGGAGGCGCT GAGGAGAGGT 60
GAGGGGGGAG GGGTCTGGGC GAGCTGCCTG GGAGGCCCGC GACGGGCAGC CTGGAGGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	86.15	0.00e+00	1370.00
IUUC-Apl-003272	Anas platyrhynchos	81.60	0.00e+00	1588.00
IUUC-Aca-005057	Anolis carolinensis	79.86	0.00e+00	1582.00
IUUC-Ame-010781	Astyanax mexicanus	75.23	0.00e+00	1529.00
IUUC-Bta-013502	Bos taurus	81.38	0.00e+00	1565.00
IUUC-Cel-018710	Caenorhabditis elegans	32.10	3.00e-73	270.00
IUUC-Cja-018754	Callithrix jacchus	89.80	0.00e+00	1867.00
IUUC-Cfa-020526	Canis familiaris	88.35	0.00e+00	1801.00
IUUC-Cpo-021568	Cavia porcellus	81.84	0.00e+00	1572.00
IUUC-Csa-023143	Chlorocebus sabaeus	90.18	0.00e+00	1844.00
IUUC-Cho-024603	Choloepus hoffmanni	61.96	0.00e+00	692.00
IUUC-Cin-025583	Ciona intestinalis	46.87	0.00e+00	860.00
IUUC-Dre-028121	Danio rerio	76.15	0.00e+00	1503.00
IUUC-Dno-029911	Dasypus novemcinctus	87.56	0.00e+00	1759.00
IUUC-Dor-030608	Dipodomys ordii	61.74	0.00e+00	718.00
IUUC-Dme-032094	Drosophila melanogaster	45.05	5.00e-89	323.00
IUUC-Eca-034253	Equus caballus	87.81	0.00e+00	1783.00
IUUC-Eeu-035084	Erinaceus europaeus	82.24	0.00e+00	944.00
IUUC-Fca-035474	Felis catus	84.98	0.00e+00	1277.00
IUUC-Fal-036985	Ficedula albicollis	74.87	0.00e+00	2049.00
IUUC-Gmo-039568	Gadus morhua	74.80	0.00e+00	1512.00
IUUC-Gga-040509	Gallus gallus	79.28	0.00e+00	1662.00
IUUC-Gac-041757	Gasterosteus aculeatus	75.47	0.00e+00	1536.00
IUUC-Hsa-046107	Homo sapiens	90.37	0.00e+00	1877.00
IUUC-Lch-050681	Latimeria chalumnae	74.53	0.00e+00	1407.00
IUUC-Loc-052474	Lepisosteus oculatus	74.36	0.00e+00	1480.00
IUUC-Laf-054273	Loxodonta africana	87.14	0.00e+00	1820.00
IUUC-Mcc-054718	Macaca mulatta	90.18	0.00e+00	1871.00
IUUC-Meu-056558	Macropus eugenii	75.99	0.00e+00	898.00
IUUC-Mga-059892	Meleagris gallopavo	81.50	0.00e+00	1587.00
IUUC-Mdo-062607	Monodelphis domestica	88.37	0.00e+00	1820.00
IUUC-Mmu-063797	Mus musculus	87.61	0.00e+00	1841.00
IUUC-Mpu-066121	Mustela putorius furo	88.67	0.00e+00	1844.00
IUUC-Mlu-067581	Myotis lucifugus	90.03	0.00e+00	1791.00
IUUC-Nle-069916	Nomascus leucogenys	86.60	0.00e+00	1741.00
IUUC-Opr-071073	Ochotona princeps	86.71	0.00e+00	1054.00
IUUC-Ont-071310	Oreochromis niloticus	75.52	0.00e+00	1513.00
IUUC-Oan-073356	Ornithorhynchus anatinus	84.08	0.00e+00	1739.00
IUUC-Ocu-074216	Oryctolagus cuniculus	90.96	0.00e+00	1837.00
IUUC-Ola-087434	Oryzias latipes	74.57	0.00e+00	1459.00
IUUC-Oga-089034	Otolemur garnettii	88.83	0.00e+00	1743.00
IUUC-Oar-090369	Ovis aries	87.71	0.00e+00	1769.00
IUUC-Ptr-090605	Pan troglodytes	90.18	0.00e+00	1871.00
IUUC-Pan-092381	Papio anubis	89.91	0.00e+00	1795.00
IUUC-Psi-093819	Pelodiscus sinensis	82.06	0.00e+00	1656.00
IUUC-Pma-094480	Petromyzon marinus	58.36	4.00e-165	575.00
IUUC-Pfo-096561	Poecilia formosa	75.20	0.00e+00	1474.00
IUUC-Pab-097643	Pongo abelii	85.89	0.00e+00	1756.00
IUUC-Pca-100944	Procavia capensis	77.62	0.00e+00	725.00
IUUC-Pva-102732	Pteropus vampyrus	77.71	0.00e+00	1555.00
IUUC-Rno-105113	Rattus norvegicus	87.48	0.00e+00	1805.00
IUUC-Tgu-117322	Taeniopygia guttata	81.33	0.00e+00	1710.00
IUUC-Tru-118705	Takifugu rubripes	63.40	0.00e+00	904.00
IUUC-Tsy-119433	Tarsius syrichta	80.75	0.00e+00	1567.00
IUUC-Tni-120631	Tetraodon nigroviridis	74.51	0.00e+00	1454.00
IUUC-Tbe-127553	Tupaia belangeri	86.77	0.00e+00	681.00
IUUC-Ttr-128260	Tursiops truncatus	88.45	0.00e+00	1811.00
IUUC-Vpa-130479	Vicugna pacos	87.48	0.00e+00	1782.00
IUUC-Xtr-132686	Xenopus tropicalis	76.67	0.00e+00	1581.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence