iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049730

Ensembl Protein ID

ENSLACP00000014580.1

UniProt Accession

H3AY59; H3AY59_LATCH

Genbank Protein ID

ENSLACP00000014580

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01100471

Gene Name

KDM2A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000012832.1	ENSLACT00000014680.1	ENSLACP00000014580.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.50e-10	40.6	367	425
E3 adaptor/Cullin RING/SCF/F-box	9.10e-06	26.0	586	683

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedek......slveCekCrewfHpaClkls....veeelpnsekwiCpkCrs 53
            Cl+C++ +++e+      +l+eC+ C e++Hp+Cl+ +    ++eelpn+  w+CpkC++
   Q: 367  ACLICEDVDREEEtksfdmKLMECSLCYEIVHPGCLEVEgdgvISEELPNC--WECPKCSQ 425
           7*********996778889********************************..******97 PP

E3 adaptor/Cullin RING/SCF/F-box

   S: 50   aqrras.rrtprqpprgpsaaakpkaglrseaaaapapapaptptpeegpdaglldrlpeeilveilklldkeellraarvcrrwqela 137
           a   +s r++pr   rg s  a    g      ++   + +     e + +++    ++++++++++++l+++el+++ +vc++w++ +
   Q: 586  ATATTSlRQAPRVVTRGSSGEADGGGGSVNGGRSSRLESESEEEENEGEEEEEEDIWMQKDVWMSVFHYLSRRELCECMQVCKTWYKWC 674
           444444277899999999999998888777776666666666666655556666666789**************************666 PP
   S: 138  sqkalwktv 146
            +k+lw ++
   Q: 675  CDKRLWTKI 683
           669**9986 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

RIKCCQQRDE LYSIFHFLCF SGWIHAVYTP QDTLVFGGNF LHSFNIPMQL RIYSIEDRTR 60
VPVKFRYPFY YEMCWYVLER YFYCLQKRSH LIKDFQRESL DLDSEGNGLE TIQIKAEEEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAATTAAAT GCTGCCAAGG CAAGAAAAAA ATAGTCTTAA AAAAGACTTT TGAACTATTT 60
TTTTTTTTTT TCCCACTCGC AACGCGACGA ACTATACTCC ATGAATCGGG AAGAAAATAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR019786--Zinc_finger_PHD-type_CS
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51058--ZF_CXXC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00367--LRR_CC

Gene Ontology

GO:0003677--F:DNA binding
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004576	Anolis carolinensis	59.18	0.00e+00	947.00
IUUC-Bta-012730	Bos taurus	54.56	0.00e+00	835.00
IUUC-Cja-019030	Callithrix jacchus	60.58	0.00e+00	969.00
IUUC-Cfa-020644	Canis familiaris	60.94	0.00e+00	975.00
IUUC-Cpo-022055	Cavia porcellus	60.24	0.00e+00	970.00
IUUC-Csa-023379	Chlorocebus sabaeus	60.67	0.00e+00	968.00
IUUC-Dno-029268	Dasypus novemcinctus	60.67	0.00e+00	968.00
IUUC-Dor-031142	Dipodomys ordii	62.37	3.00e-179	622.00
IUUC-Ete-032467	Echinops telfairi	56.68	0.00e+00	865.00
IUUC-Eca-033526	Equus caballus	59.75	0.00e+00	965.00
IUUC-Eeu-035273	Erinaceus europaeus	54.55	1.00e-180	627.00
IUUC-Fca-035532	Felis catus	60.78	0.00e+00	964.00
IUUC-Fal-037140	Ficedula albicollis	59.59	0.00e+00	953.00
IUUC-Hsa-046180	Homo sapiens	60.88	0.00e+00	978.00
IUUC-Itr-048198	Ictidomys tridecemlineatus	63.93	0.00e+00	811.00
IUUC-Laf-053939	Loxodonta africana	60.43	0.00e+00	972.00
IUUC-Mcc-054600	Macaca mulatta	60.67	0.00e+00	969.00
IUUC-Meu-056314	Macropus eugenii	61.09	0.00e+00	739.00
IUUC-Mmr-060865	Microcebus murinus	60.47	0.00e+00	971.00
IUUC-Mdo-062567	Monodelphis domestica	60.89	0.00e+00	968.00
IUUC-Mmu-063782	Mus musculus	60.47	0.00e+00	969.00
IUUC-Mpu-066055	Mustela putorius furo	61.05	0.00e+00	981.00
IUUC-Nle-069668	Nomascus leucogenys	60.56	0.00e+00	962.00
IUUC-Opr-070225	Ochotona princeps	59.30	0.00e+00	948.00
IUUC-Ocu-074710	Oryctolagus cuniculus	60.63	0.00e+00	959.00
IUUC-Oga-088644	Otolemur garnettii	60.56	0.00e+00	964.00
IUUC-Oar-089193	Ovis aries	60.39	0.00e+00	958.00
IUUC-Ptr-091523	Pan troglodytes	60.88	0.00e+00	978.00
IUUC-Pan-092415	Papio anubis	60.67	0.00e+00	969.00
IUUC-Psi-093607	Pelodiscus sinensis	62.44	0.00e+00	691.00
IUUC-Pab-098580	Pongo abelii	63.33	0.00e+00	749.00
IUUC-Pca-100670	Procavia capensis	57.55	0.00e+00	897.00
IUUC-Pva-102416	Pteropus vampyrus	54.35	0.00e+00	824.00
IUUC-Rno-105814	Rattus norvegicus	60.84	0.00e+00	973.00
IUUC-Sha-106693	Sarcophilus harrisii	59.24	0.00e+00	864.00
IUUC-Sar-113568	Sorex araneus	58.23	0.00e+00	915.00
IUUC-Ssc-116337	Sus scrofa	59.64	0.00e+00	893.00
IUUC-Tgu-117298	Taeniopygia guttata	59.96	0.00e+00	950.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence