iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067723

Ensembl Protein ID

ENSMLUP00000011702.2

UniProt Accession

G1PLG8; G1PLG8_MYOLU

Genbank Protein ID

ENSMLUP00000011702

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AAPE02013977

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000012864.2	ENSMLUT00000012865.2	ENSMLUP00000011702.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.60e-09	36.7	169	216

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 169  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 216
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

SFAEILKELD EYYEKFKRET DSNQKRRALH CIQRALIRSQ ELGDEKIQIV SQMVELVENR 60
TRQVDSHVEL FEAHQEVNDT TGHSGKAGQD KSKNETITQA EKPNNKRSRR QRNNENRENA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCTTTGCAG AAATCCTGAA GGAGCTAGAT GAGTATTACG AGAAGTTTAA GCGGGAGACG 60
GACAGCAACC AGAAGAGGAG AGCGTTGCAC TGCATTCAGA GAGCCCTGAT CCGCAGCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013507	Bos taurus	92.31	1.00e-94	338.00
IUUC-Cpo-022286	Cavia porcellus	93.64	2.00e-103	368.00
IUUC-Cho-024577	Choloepus hoffmanni	95.28	8.00e-104	369.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	5.00e-16	78.60
IUUC-Dor-030315	Dipodomys ordii	89.36	6.00e-103	367.00
IUUC-Ete-032408	Echinops telfairi	93.13	2.00e-98	352.00
IUUC-Eca-034244	Equus caballus	97.01	5.00e-106	376.00
IUUC-Eeu-035285	Erinaceus europaeus	57.53	8.00e-53	199.00
IUUC-Ggo-045481	Gorilla gorilla	87.71	9.00e-97	347.00
IUUC-Hsa-046170	Homo sapiens	87.71	1.00e-96	347.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	96.58	2.00e-106	377.00
IUUC-Mcc-055031	Macaca mulatta	88.46	1.00e-96	346.00
IUUC-Meu-056248	Macropus eugenii	94.51	8.00e-104	369.00
IUUC-Mga-059217	Meleagris gallopavo	92.70	4.00e-100	357.00
IUUC-Mmr-061581	Microcebus murinus	94.49	5.00e-105	373.00
IUUC-Mpu-066479	Mustela putorius furo	97.87	4.00e-107	380.00
IUUC-Opr-070835	Ochotona princeps	85.84	6.00e-85	306.00
IUUC-Ocu-073779	Oryctolagus cuniculus	90.60	4.00e-95	340.00
IUUC-Pan-091896	Papio anubis	88.46	8.00e-97	347.00
IUUC-Pma-094265	Petromyzon marinus	75.34	2.00e-33	134.00
IUUC-Pva-102753	Pteropus vampyrus	93.59	7.00e-95	340.00
IUUC-Rno-105964	Rattus norvegicus	93.16	7.00e-93	332.00
IUUC-Tni-119980	Tetraodon nigroviridis	59.16	6.00e-71	260.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence