iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062307

UUCD1 version

UUC-MoD-00905

Ensembl Protein ID

ENSMODP00000011310.3

UniProt Accession

F7FR06; F7FR06_MONDO

Protein Name

Uncharacterized protein

Gene Name

ABCB10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000009056.3	ENSMODT00000011529.3	ENSMODP00000011310.3
ENSMODG00000009056.3	ENSMODT00000011512.3	ENSMODP00000011293.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.70e-21	74.5	424	461
UBD/Beta-Prp	5.20e-43	147.5	271	482

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH ++v c++f ++ ++l++Gs D+t+++W++ +g+++
   Q: 424  GHLADVDCVKFhPNsNYLATGSTDKTVRLWSTQQGNSV 461
           899*********777****************9999876 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   +spd++lla+g++++++k+w+++++kl                                ++ l gh ++v++++f +d++ l++
   Q: 271  LNTAEISPDNKLLAAGFDNSCVKLWSLRSKKLksephqvdvsrirlacdvldeeeddddnvgteMKILRGHCGPVYSTRFLSDSSGLLS 359
           5667889********************************************************************************** PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ i+ wdl +++ ++ ++gh + v++l++sp + +++sGshdrt+r+w  +  + l+ + +gh + v cv++hp++n+l++Gs+D
   Q: 360  CSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPCSLYFASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATGSTD 447
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsng.k 193
           +tvrlW+ ++g+ +r +tg h ++v sl+f++n   
   Q: 448  KTVRLWSTQQGNSVRLFTG-HRGPVLSLAFSPNAaV 482
           ******************9.************9862 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MKRVRTEQIQ MAVSCYLKRR QYVDSEGPLK QGLRLSQTPE EMAANLTVQS ESGCANIVSA 60
APCQAEPQQY EVQFGRLRNF LTDSDSQHSH EVMPLLYPLF VYLHLHMVQN GLKSTVDSFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCTTTTCCA GACTCCTCAC TAACTAACTA ACGAGTCTAT ACTTACCCAG TCGGTGTGTC 60
CCGGGGAAGG GGAACGAAGA AGAAGGGCAG GCTAAATGAC TGACCGAGCA AGAAGTCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR003593--AAA+_ATPase
IPR011527--ABC1_TM_dom
IPR003439--ABC_transporter-like
IPR017871--ABC_transporter_CS
IPR020472--G-protein_beta_WD-40_rep
IPR027417--P-loop_NTPase
IPR007582--TFIID_NTD2
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50929--ABC_TM1F
PS00211--ABC_TRANSPORTER_1
PS50893--ABC_TRANSPORTER_2
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00664--ABC_membrane
PF00005--ABC_tran
PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00382--AAA
SM00320--WD40

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005524--F:ATP binding
GO:0042626--F:ATPase activity, coupled to transmembrane movement of substances

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	93.96	0.00e+00	873.00
IUUC-Apl-003636	Anas platyrhynchos	93.15	0.00e+00	924.00
IUUC-Aca-004229	Anolis carolinensis	93.12	0.00e+00	897.00
IUUC-Ame-010599	Astyanax mexicanus	66.46	0.00e+00	689.00
IUUC-Bta-013404	Bos taurus	90.19	0.00e+00	830.00
IUUC-Cja-019643	Callithrix jacchus	94.17	0.00e+00	877.00
IUUC-Cfa-020913	Canis familiaris	94.38	0.00e+00	877.00
IUUC-Cpo-021777	Cavia porcellus	93.33	0.00e+00	865.00
IUUC-Csa-024184	Chlorocebus sabaeus	94.17	0.00e+00	880.00
IUUC-Cho-024638	Choloepus hoffmanni	94.17	0.00e+00	864.00
IUUC-Cin-025618	Ciona intestinalis	33.74	2.00e-66	246.00
IUUC-Dre-028817	Danio rerio	66.46	0.00e+00	685.00
IUUC-Dno-029969	Dasypus novemcinctus	86.43	0.00e+00	826.00
IUUC-Dor-031117	Dipodomys ordii	92.28	0.00e+00	881.00
IUUC-Ete-032712	Echinops telfairi	85.21	0.00e+00	762.00
IUUC-Eca-033742	Equus caballus	94.17	0.00e+00	875.00
IUUC-Eeu-035096	Erinaceus europaeus	91.48	0.00e+00	888.00
IUUC-Fca-035769	Felis catus	93.36	0.00e+00	899.00
IUUC-Fal-036645	Ficedula albicollis	93.12	0.00e+00	928.00
IUUC-Gmo-038636	Gadus morhua	67.42	0.00e+00	694.00
IUUC-Gga-040144	Gallus gallus	92.71	0.00e+00	892.00
IUUC-Gac-041716	Gasterosteus aculeatus	66.05	0.00e+00	649.00
IUUC-Ggo-044568	Gorilla gorilla	94.38	0.00e+00	879.00
IUUC-Hsa-046178	Homo sapiens	94.38	0.00e+00	879.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	86.25	0.00e+00	865.00
IUUC-Lch-050501	Latimeria chalumnae	78.10	0.00e+00	741.00
IUUC-Loc-052895	Lepisosteus oculatus	82.17	1.00e-128	453.00
IUUC-Laf-053950	Loxodonta africana	90.42	0.00e+00	845.00
IUUC-Mcc-055450	Macaca mulatta	94.38	0.00e+00	879.00
IUUC-Meu-056182	Macropus eugenii	91.88	0.00e+00	849.00
IUUC-Mga-059619	Meleagris gallopavo	92.92	0.00e+00	895.00
IUUC-Mmr-061074	Microcebus murinus	92.74	0.00e+00	884.00
IUUC-Mmu-063226	Mus musculus	90.83	0.00e+00	840.00
IUUC-Mpu-066016	Mustela putorius furo	93.95	0.00e+00	865.00
IUUC-Mlu-067257	Myotis lucifugus	86.50	0.00e+00	872.00
IUUC-Nle-070139	Nomascus leucogenys	94.58	0.00e+00	881.00
IUUC-Opr-070243	Ochotona princeps	89.38	0.00e+00	854.00
IUUC-Ont-072686	Oreochromis niloticus	67.82	0.00e+00	691.00
IUUC-Oan-073670	Ornithorhynchus anatinus	83.76	0.00e+00	659.00
IUUC-Ocu-074525	Oryctolagus cuniculus	93.54	0.00e+00	894.00
IUUC-Ola-086524	Oryzias latipes	67.48	0.00e+00	698.00
IUUC-Oga-088540	Otolemur garnettii	93.54	0.00e+00	872.00
IUUC-Oar-089793	Ovis aries	88.75	0.00e+00	796.00
IUUC-Ptr-091154	Pan troglodytes	94.38	0.00e+00	879.00
IUUC-Pan-092759	Papio anubis	94.38	0.00e+00	879.00
IUUC-Psi-094008	Pelodiscus sinensis	93.33	0.00e+00	914.00
IUUC-Pma-094593	Petromyzon marinus	44.20	3.00e-108	385.00
IUUC-Pfo-097409	Poecilia formosa	66.19	0.00e+00	657.00
IUUC-Pab-097946	Pongo abelii	80.62	0.00e+00	728.00
IUUC-Pca-100727	Procavia capensis	85.62	0.00e+00	769.00
IUUC-Pva-103211	Pteropus vampyrus	81.00	0.00e+00	793.00
IUUC-Rno-105236	Rattus norvegicus	91.67	0.00e+00	842.00
IUUC-Sha-106833	Sarcophilus harrisii	96.89	0.00e+00	922.00
IUUC-Sar-113381	Sorex araneus	93.75	0.00e+00	905.00
IUUC-Ssc-116421	Sus scrofa	91.44	0.00e+00	907.00
IUUC-Tgu-117143	Taeniopygia guttata	93.96	0.00e+00	931.00
IUUC-Tru-118680	Takifugu rubripes	66.06	0.00e+00	683.00
IUUC-Tsy-119622	Tarsius syrichta	77.45	0.00e+00	642.00
IUUC-Tni-120131	Tetraodon nigroviridis	65.46	0.00e+00	682.00
IUUC-Tbe-127656	Tupaia belangeri	89.77	1.00e-81	297.00
IUUC-Ttr-129171	Tursiops truncatus	91.02	0.00e+00	845.00
IUUC-Xtr-132241	Xenopus tropicalis	79.58	0.00e+00	761.00
IUUC-Xma-133554	Xiphophorus maculatus	67.21	0.00e+00	685.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence