iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-006613

UUCD1 version

UUC-ArT-01693

Ensembl Protein ID

AT4G33620.1

UniProt Accession

Q0WKV8; F4JJ09; O81879; ULP2A_ARATH

Genbank Protein ID

CAA20575.1; CAB80079.1; AEE86254.2; BAF02249.1

Protein Name

Probable ubiquitin-like-specific protease 2A

Genbank Nucleotide ID

AL031394; AL161583; CP002687; AK230453

Gene Name

ULP2A; At4g33620; T16L1.110

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT4G33620	AT4G33620.1	AT4G33620.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/ULP	4.50e-43	148.3	306	495

Active Site

Position(s)	Description	Evidence
400	N/A	{ECO:0000250}
430		{ECO:0000250}
485		{ECO:0000250}

Domain Profile

DUB/ULP

   S: 2    svtnedlkcLeegeflnDviidfylkylvleklkkekverihifssffykklkqkerr............rvktwtrkvdlfekdlifvpineaaHWs 87
            v+++d++ L++++f+nD+iidfy+k +++++++ ++  r h+f+ ff++kl++ ++             rv++wt++vdlfekd+if+pin + HWs
   Q: 306  VVRKQDIELLKPRRFINDTIIDFYIK-YLKNRISPKERGRFHFFNCFFFRKLANLDKGtpstcggreayqRVQKWTKNVDLFEKDYIFIPINCSFHWS 402
           6899**********************.66889999******************9665567999*********************************** PP
   S: 88   lavvcf.............kkksilllDSlrgasksnvvkklreylevevkkkskr....efskeklkgsnpkvpqQkNssDCGvyvlqyves 163
           l+++c              + ++il+lDS++g++k   +++   yl++e k ++++    +    ++++ + ++pqQ+Ns+DCG+++l+y + 
   Q: 403  LVIICHpgelvpshvenpqRVPCILHLDSIKGSHKGGLINIFPSYLREEWKARHENttndSSRAPNMQSISLELPQQENSFDCGLFLLHYLDL 495
           ******************999***************************7766554400114455689999999*****************976 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMOs to their mature forms and deconjugation of SUMO from targeted proteins.

Protein Sequence
(Fasta)

MTLRSVQSRS KRKPIDVFDY SDEDDRVEEE SKKLLRKFDS PVTKKHHCAI DKYEFLRCFA 60
KDTQSESKVL QHIVIDVEVP VKEEPSRCEL SGDGNSDLID VISNGSHRRI GIDSLTSSSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGAATCGA AATTCAAAAT TCCGTCTCTT TGGTACAGAA TACGCTTTGG ACCTTCTCGA 60
GCCCGTCGGA ACTGTAACTC AGTATTATTC TGGCGCCGAT GACTCTCCGG TCAGTTCAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR003653--Peptidase_C48_C

PROSITE

PS50600--ULP_PROTEASE

Pfam

PF02902--Peptidase_C48

Gene Ontology

GO:0016929--F:SUMO-specific protease activity
GO:0016926--P:protein desumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001517	Ailuropoda melanoleuca	28.81	3.00e-27	117.00
IUUC-Apl-003302	Anas platyrhynchos	28.88	6.00e-28	119.00
IUUC-Aca-005366	Anolis carolinensis	37.12	4.00e-18	86.70
IUUC-Aly-005759	Arabidopsis lyrata	89.45	0.00e+00	1313.00
IUUC-Acl-008018	Aspergillus clavatus	39.69	2.00e-16	80.90
IUUC-Afu-008974	Aspergillus fumigatus	39.71	2.00e-17	83.60
IUUC-Ame-011446	Astyanax mexicanus	41.18	2.00e-19	89.70
IUUC-Bgr-012266	Blumeria graminis	34.40	6.00e-15	76.30
IUUC-Bta-012652	Bos taurus	27.81	9.00e-29	122.00
IUUC-Bol-015079	Brassica oleracea	75.82	0.00e+00	1048.00
IUUC-Bra-017420	Brassica rapa	75.98	0.00e+00	1011.00
IUUC-Cja-018890	Callithrix jacchus	28.15	2.00e-28	120.00
IUUC-Cfa-020923	Canis familiaris	28.86	1.00e-28	121.00
IUUC-Cpo-022468	Cavia porcellus	25.50	1.00e-18	88.20
IUUC-Csa-024235	Chlorocebus sabaeus	27.81	2.00e-28	120.00
IUUC-Cin-025522	Ciona intestinalis	35.53	2.00e-17	82.40
IUUC-Csv-025934	Ciona savignyi	37.61	1.00e-17	82.80
IUUC-Cne-027012	Cryptococcus neoformans	38.40	6.00e-17	83.20
IUUC-Dre-028481	Danio rerio	31.07	4.00e-30	126.00
IUUC-Dor-031007	Dipodomys ordii	37.12	8.00e-13	69.30
IUUC-Dse-031477	Dothistroma septosporum	33.62	3.00e-11	64.30
IUUC-Dme-031729	Drosophila melanogaster	33.98	4.00e-32	132.00
IUUC-Eca-033398	Equus caballus	27.48	8.00e-29	122.00
IUUC-Eeu-034595	Erinaceus europaeus	27.36	3.00e-26	113.00
IUUC-Fca-036245	Felis catus	27.96	8.00e-29	122.00
IUUC-Ggr-039948	Gaeumannomyces graminis	27.90	2.00e-16	80.50
IUUC-Gac-041712	Gasterosteus aculeatus	33.33	6.00e-32	130.00
IUUC-Ggo-044423	Gorilla gorilla	27.48	2.00e-28	120.00
IUUC-Hsa-046011	Homo sapiens	27.48	2.00e-28	120.00
IUUC-Itr-048853	Ictidomys tridecemlineatus	28.15	4.00e-28	119.00
IUUC-Kpa-049348	Komagataella pastoris	27.59	1.00e-12	67.40
IUUC-Laf-053556	Loxodonta africana	27.15	2.00e-28	120.00
IUUC-Mcc-055633	Macaca mulatta	27.81	3.00e-28	120.00
IUUC-Meu-056793	Macropus eugenii	32.29	8.00e-18	85.50
IUUC-Mor-057033	Magnaporthe oryzae	36.04	1.00e-14	75.10
IUUC-Mpo-057440	Magnaporthe poae	32.73	3.00e-14	73.20
IUUC-Mga-059926	Meleagris gallopavo	28.57	2.00e-26	114.00
IUUC-Mmr-061064	Microcebus murinus	27.48	2.00e-28	120.00
IUUC-Mdo-061950	Monodelphis domestica	27.48	5.00e-28	119.00
IUUC-Mmu-063995	Mus musculus	26.78	4.00e-23	103.00
IUUC-Mpu-066660	Mustela putorius furo	27.81	3.00e-28	120.00
IUUC-Mlu-067173	Myotis lucifugus	28.38	3.00e-29	123.00
IUUC-Ncr-068866	Neurospora crassa	50.00	6.00e-10	59.70
IUUC-Nle-070111	Nomascus leucogenys	28.15	2.00e-28	120.00
IUUC-Ont-071476	Oreochromis niloticus	30.96	2.00e-31	130.00
IUUC-Oan-073520	Ornithorhynchus anatinus	29.97	5.00e-25	109.00
IUUC-Ocu-073836	Oryctolagus cuniculus	37.12	7.00e-13	69.30
IUUC-Ola-086817	Oryzias latipes	40.54	5.00e-19	86.30
IUUC-Oga-088400	Otolemur garnettii	27.48	6.00e-28	119.00
IUUC-Oar-090273	Ovis aries	27.81	2.00e-28	120.00
IUUC-Ptr-090796	Pan troglodytes	27.48	3.00e-28	120.00
IUUC-Pan-091782	Papio anubis	27.81	2.00e-28	120.00
IUUC-Pab-098505	Pongo abelii	28.43	1.00e-28	121.00
IUUC-Pca-100196	Procavia capensis	27.00	1.00e-21	98.20
IUUC-Pva-102390	Pteropus vampyrus	28.04	9.00e-29	121.00
IUUC-Rno-105145	Rattus norvegicus	27.81	3.00e-23	103.00
IUUC-Sha-107054	Sarcophilus harrisii	28.15	2.00e-28	120.00
IUUC-Spo-108052	Schizosaccharomyces pombe	35.22	5.00e-29	122.00
IUUC-Stu-111985	Solanum tuberosum	31.95	8.00e-18	84.70
IUUC-Sar-113324	Sorex araneus	28.71	2.00e-28	120.00
IUUC-Ssc-116333	Sus scrofa	27.81	1.00e-28	121.00
IUUC-Tgu-116626	Taeniopygia guttata	28.52	2.00e-22	99.40
IUUC-Tru-118544	Takifugu rubripes	39.13	7.00e-19	86.30
IUUC-Tsy-118994	Tarsius syrichta	36.36	1.00e-12	68.20
IUUC-Tni-120181	Tetraodon nigroviridis	40.00	2.00e-19	88.20
IUUC-Tvi-122488	Trichoderma virens	37.19	2.00e-13	70.90
IUUC-Ttr-129225	Tursiops truncatus	27.76	8.00e-29	122.00
IUUC-Vpa-130805	Vicugna pacos	27.48	1.00e-28	121.00
IUUC-Xtr-132523	Xenopus tropicalis	36.26	7.00e-20	92.80

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence