iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012315

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02020720

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000012095.5	ENSBTAT00000016037.5	ENSBTAP00000016037.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.40e-41	137.6	639	674
UBD/Beta-Prp	2.00e-63	214.4	57	266

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtg 33
           gHt+++t+la+   +d++lvs+s+Dgt +vWD+ + 
   Q: 639  GHTAKITSLAWsphHDGRLVSASYDGTAQVWDTLQE 674
           8***********8766****************7665 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcl 129
           + +l gh+++v+  +f ++     + +t+s+D+t+k+wd+ t + v     h++++ +l++sp  +d +vsG++  ++ ++ l+ +   
   Q: 57   VGELVGHTEKVSGFTFCHHPGqynLCATSSDDGTVKIWDVGTKTVVTEHALHQHTISALHWSPrVKDLIVSGDEKGVVFCYWLNRNDSQ 145
           67899********99988754577***************************************666**************966666666 PP
   S: 130  eetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls............fdsng............ 192
           +  l ++ +++ c++ +p   +l++ G +D++v + d+ k g+++++l+g h+d ++s++                +            
   Q: 146  H--LFIEPRTIFCLTCSPHHeDLVAIGYKDGIVVIIDIsKKGEVMHRLRG-HDDEIHSIAwcpllgedclsiN---Qeenseepempng 228
           5..899999999999999999*****************999********9.*********7777777775540...2556788888888 PP
   S: 193  ...........kelvsgsldgtvklwdlqtgecvrtln 219
                       +l++gs+d+t+++w++++g+ v+tl+
   Q: 229  kvitqtpvtkgCYLATGSKDQTIRIWSCSRGRGVMTLK 266
           99999999999********************9999875 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MGQEPRTLPP SPNWYCSRCS DAVPGGLFGF AARTSVFLVR VGPGADAIPG TPPFRVVGEL 60
VGHTEKVSGF TFCHHPGQYN LCATSSDDGT VKIWDVGTKT VVTEHALHQH TISALHWSPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGACAGG AACCGCGCAC GTTGCCGCCC TCCCCTAACT GGTACTGCTC CCGATGCAGC 60
GATGCCGTGC CCGGGGGCCT CTTCGGCTTC GCGGCGCGGA CTTCGGTCTT CCTTGTCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	88.85	0.00e+00	2630.00
IUUC-Apl-003586	Anas platyrhynchos	62.76	0.00e+00	1641.00
IUUC-Aca-004956	Anolis carolinensis	62.43	0.00e+00	1865.00
IUUC-Ame-010753	Astyanax mexicanus	62.34	0.00e+00	994.00
IUUC-Cja-019334	Callithrix jacchus	86.34	0.00e+00	2633.00
IUUC-Cfa-021254	Canis familiaris	88.90	0.00e+00	2702.00
IUUC-Cpo-021984	Cavia porcellus	80.28	0.00e+00	2311.00
IUUC-Csa-023650	Chlorocebus sabaeus	86.97	0.00e+00	2605.00
IUUC-Cho-024860	Choloepus hoffmanni	81.88	0.00e+00	2395.00
IUUC-Cin-025778	Ciona intestinalis	41.57	7.00e-160	558.00
IUUC-Csv-026313	Ciona savignyi	40.87	5.00e-164	571.00
IUUC-Dre-028096	Danio rerio	63.14	0.00e+00	1005.00
IUUC-Dno-029799	Dasypus novemcinctus	88.09	0.00e+00	2217.00
IUUC-Dor-030885	Dipodomys ordii	74.30	0.00e+00	1081.00
IUUC-Ete-032918	Echinops telfairi	79.67	0.00e+00	2370.00
IUUC-Eca-034144	Equus caballus	88.35	0.00e+00	2572.00
IUUC-Eeu-034843	Erinaceus europaeus	78.02	0.00e+00	1781.00
IUUC-Fca-035948	Felis catus	88.27	0.00e+00	2618.00
IUUC-Fal-037303	Ficedula albicollis	61.91	0.00e+00	1810.00
IUUC-Gmo-039591	Gadus morhua	53.56	0.00e+00	845.00
IUUC-Gga-040570	Gallus gallus	62.81	0.00e+00	1632.00
IUUC-Gac-042646	Gasterosteus aculeatus	48.22	0.00e+00	1346.00
IUUC-Ggo-045605	Gorilla gorilla	80.15	0.00e+00	1813.00
IUUC-Hsa-046122	Homo sapiens	87.44	0.00e+00	2591.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	89.29	0.00e+00	2272.00
IUUC-Lch-050489	Latimeria chalumnae	49.76	0.00e+00	847.00
IUUC-Loc-052259	Lepisosteus oculatus	60.36	0.00e+00	968.00
IUUC-Laf-053338	Loxodonta africana	86.61	0.00e+00	2572.00
IUUC-Mcc-055442	Macaca mulatta	87.03	0.00e+00	2606.00
IUUC-Meu-056245	Macropus eugenii	83.37	0.00e+00	872.00
IUUC-Mga-060202	Meleagris gallopavo	62.76	0.00e+00	1700.00
IUUC-Mmr-061730	Microcebus murinus	86.91	0.00e+00	2599.00
IUUC-Mdo-062880	Monodelphis domestica	73.68	0.00e+00	2208.00
IUUC-Mmu-063930	Mus musculus	80.24	0.00e+00	2298.00
IUUC-Mpu-066605	Mustela putorius furo	87.94	0.00e+00	2635.00
IUUC-Mlu-067765	Myotis lucifugus	88.54	0.00e+00	2688.00
IUUC-Nle-069183	Nomascus leucogenys	87.05	0.00e+00	2564.00
IUUC-Opr-070659	Ochotona princeps	75.36	0.00e+00	1169.00
IUUC-Ont-072356	Oreochromis niloticus	62.00	0.00e+00	1007.00
IUUC-Oan-073056	Ornithorhynchus anatinus	71.51	0.00e+00	1998.00
IUUC-Ocu-073881	Oryctolagus cuniculus	86.31	0.00e+00	2635.00
IUUC-Ola-087120	Oryzias latipes	58.94	7.00e-69	253.00
IUUC-Olu-087648	Ostreococcus lucimarinus	26.40	3.00e-33	137.00
IUUC-Oga-088343	Otolemur garnettii	87.45	0.00e+00	2610.00
IUUC-Oar-089257	Ovis aries	96.83	0.00e+00	2917.00
IUUC-Ptr-090497	Pan troglodytes	87.24	0.00e+00	2561.00
IUUC-Pan-092638	Papio anubis	87.22	0.00e+00	2613.00
IUUC-Psi-093096	Pelodiscus sinensis	65.29	0.00e+00	1645.00
IUUC-Pma-094571	Petromyzon marinus	43.47	9.00e-83	300.00
IUUC-Pfo-096742	Poecilia formosa	49.14	0.00e+00	1382.00
IUUC-Pab-098153	Pongo abelii	86.72	0.00e+00	2623.00
IUUC-Pca-100957	Procavia capensis	79.87	0.00e+00	2373.00
IUUC-Pva-102439	Pteropus vampyrus	89.83	0.00e+00	2690.00
IUUC-Rno-105891	Rattus norvegicus	80.58	0.00e+00	2287.00
IUUC-Sha-107181	Sarcophilus harrisii	73.95	0.00e+00	2090.00
IUUC-Ssc-115413	Sus scrofa	90.77	0.00e+00	2763.00
IUUC-Tgu-117082	Taeniopygia guttata	63.13	0.00e+00	1783.00
IUUC-Tru-118491	Takifugu rubripes	60.39	0.00e+00	953.00
IUUC-Tsy-119629	Tarsius syrichta	93.43	4.00e-167	582.00
IUUC-Tni-120240	Tetraodon nigroviridis	60.11	0.00e+00	960.00
IUUC-Tbe-127673	Tupaia belangeri	76.24	0.00e+00	2096.00
IUUC-Ttr-128562	Tursiops truncatus	89.76	0.00e+00	2693.00
IUUC-Vpa-130596	Vicugna pacos	85.97	0.00e+00	1877.00
IUUC-Xtr-132469	Xenopus tropicalis	55.45	0.00e+00	1602.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence