iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021984

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02022533

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000003468.3	ENSCPOT00000003512.2	ENSCPOP00000003133.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.90e-43	142.3	636	668
UBD/Beta-Prp	1.90e-69	234.1	57	265

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt+++tcla+   +d++lvs+s+Dgt +vWD+
   Q: 636  GHTAKITCLAWsphHDGILVSASYDGTAQVWDT 668
           8***********8766****************6 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcl 129
           + +l gh++ v+  +fs++     + +t+s+D+t+k+wd++t + v     h++++ +l++sp  +d +vsG++  ++ ++ ++ +   
   Q: 57   IGELVGHTERVSGFTFSHHPGqynLCATSSDDGTVKIWDVETKTVVTEHALHQHTIAALHWSPrVKDLIVSGDEKGVVFCYWINRNDSQ 145
           7899**************965677***************************************666**************977777777 PP
   S: 130  eetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls............fdsng............ 192
           +  l ++ +++ c++ +p   +l++ G +D++v + d+ k g+++++l+g h+d ++s+                 +            
   Q: 146  R--LFVEPRTIFCLTCSPHHeDLVAIGYKDGIVVIIDIsKKGEVIHRLRG-HDDEIHSIVwcplpgedclsvN---Qeenseepeipne 228
           6..888888999999999888*****************999********9.*********7777777775540...2556777888888 PP
   S: 193  ...........kelvsgsldgtvklwdlqtgecvrtl 218
                       +l++gs+d+tv++w++ +g+ v+tl
   Q: 229  kvtpptteakgCYLATGSKDQTVRIWSCARGRGVMTL 265
           88888888888********************999987 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MGPEPQTLPP SPNWYCTRCS DAVPGGLFGF AARTSVFLVR VGPGAGATAG TPPFRVIGEL 60
VGHTERVSGF TFSHHPGQYN LCATSSDDGT VKIWDVETKT VVTEHALHQH TIAALHWSPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCCGG AGCCGCAGAC GCTGCCACCC TCCCCGAACT GGTACTGCAC CCGCTGCAGC 60
GATGCCGTGC CGGGCGGCCT CTTCGGCTTC GCAGCGCGGA CCTCTGTCTT CCTGGTCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	80.68	0.00e+00	2402.00
IUUC-Apl-003586	Anas platyrhynchos	59.01	0.00e+00	1584.00
IUUC-Aca-004956	Anolis carolinensis	60.45	0.00e+00	1800.00
IUUC-Ame-010753	Astyanax mexicanus	61.58	0.00e+00	970.00
IUUC-Bta-012315	Bos taurus	80.08	0.00e+00	2407.00
IUUC-Cja-019334	Callithrix jacchus	81.50	0.00e+00	2476.00
IUUC-Cfa-021254	Canis familiaris	80.29	0.00e+00	2452.00
IUUC-Csa-023650	Chlorocebus sabaeus	80.35	0.00e+00	2428.00
IUUC-Cho-024860	Choloepus hoffmanni	76.33	0.00e+00	2221.00
IUUC-Cin-025778	Ciona intestinalis	40.86	4.00e-157	548.00
IUUC-Csv-026313	Ciona savignyi	40.58	2.00e-163	569.00
IUUC-Dre-028096	Danio rerio	50.46	0.00e+00	1419.00
IUUC-Dno-029799	Dasypus novemcinctus	83.70	0.00e+00	2127.00
IUUC-Dor-030885	Dipodomys ordii	91.48	8.00e-165	575.00
IUUC-Ete-032918	Echinops telfairi	75.56	0.00e+00	2242.00
IUUC-Eca-034144	Equus caballus	81.06	0.00e+00	2376.00
IUUC-Eeu-034843	Erinaceus europaeus	73.31	0.00e+00	1666.00
IUUC-Fca-035948	Felis catus	80.58	0.00e+00	2403.00
IUUC-Fal-037303	Ficedula albicollis	59.92	0.00e+00	1751.00
IUUC-Gmo-039591	Gadus morhua	52.13	0.00e+00	826.00
IUUC-Gga-040570	Gallus gallus	59.22	0.00e+00	1594.00
IUUC-Gac-042646	Gasterosteus aculeatus	47.25	0.00e+00	1318.00
IUUC-Ggo-045605	Gorilla gorilla	74.67	0.00e+00	1714.00
IUUC-Hsa-046122	Homo sapiens	81.72	0.00e+00	2428.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	86.71	0.00e+00	2199.00
IUUC-Lch-050489	Latimeria chalumnae	53.24	9.00e-174	604.00
IUUC-Loc-052259	Lepisosteus oculatus	58.62	0.00e+00	937.00
IUUC-Laf-053338	Loxodonta africana	81.00	0.00e+00	2408.00
IUUC-Mcc-055442	Macaca mulatta	80.55	0.00e+00	2427.00
IUUC-Meu-056245	Macropus eugenii	79.88	0.00e+00	837.00
IUUC-Mga-060202	Meleagris gallopavo	59.71	0.00e+00	1667.00
IUUC-Mmr-061730	Microcebus murinus	80.96	0.00e+00	2412.00
IUUC-Mdo-062880	Monodelphis domestica	69.51	0.00e+00	2084.00
IUUC-Mmu-063930	Mus musculus	78.49	0.00e+00	2216.00
IUUC-Mpu-066605	Mustela putorius furo	80.20	0.00e+00	2417.00
IUUC-Mlu-067765	Myotis lucifugus	80.62	0.00e+00	2439.00
IUUC-Nle-069183	Nomascus leucogenys	81.21	0.00e+00	2394.00
IUUC-Opr-070659	Ochotona princeps	71.10	0.00e+00	1069.00
IUUC-Ont-072356	Oreochromis niloticus	60.83	0.00e+00	982.00
IUUC-Oan-073056	Ornithorhynchus anatinus	67.95	0.00e+00	1914.00
IUUC-Ocu-073881	Oryctolagus cuniculus	82.06	0.00e+00	2485.00
IUUC-Ola-087120	Oryzias latipes	56.04	9.00e-66	242.00
IUUC-Olu-087648	Ostreococcus lucimarinus	26.20	1.00e-31	132.00
IUUC-Oga-088343	Otolemur garnettii	82.06	0.00e+00	2455.00
IUUC-Oar-089257	Ovis aries	80.68	0.00e+00	2426.00
IUUC-Ptr-090497	Pan troglodytes	81.53	0.00e+00	2399.00
IUUC-Pan-092638	Papio anubis	81.34	0.00e+00	2432.00
IUUC-Psi-093096	Pelodiscus sinensis	62.26	0.00e+00	1588.00
IUUC-Pma-094571	Petromyzon marinus	39.55	9.00e-80	290.00
IUUC-Pfo-096742	Poecilia formosa	47.92	0.00e+00	1360.00
IUUC-Pab-098153	Pongo abelii	81.79	0.00e+00	2466.00
IUUC-Pca-100957	Procavia capensis	74.42	0.00e+00	2212.00
IUUC-Pva-102439	Pteropus vampyrus	80.56	0.00e+00	2456.00
IUUC-Rno-105891	Rattus norvegicus	78.81	0.00e+00	2211.00
IUUC-Sha-107181	Sarcophilus harrisii	69.85	0.00e+00	1989.00
IUUC-Ssc-115413	Sus scrofa	80.11	0.00e+00	2455.00
IUUC-Tgu-117082	Taeniopygia guttata	60.71	0.00e+00	1736.00
IUUC-Tru-118491	Takifugu rubripes	58.32	0.00e+00	924.00
IUUC-Tsy-119629	Tarsius syrichta	89.27	2.00e-158	553.00
IUUC-Tni-120240	Tetraodon nigroviridis	58.36	0.00e+00	917.00
IUUC-Tbe-127673	Tupaia belangeri	71.63	0.00e+00	1979.00
IUUC-Ttr-128562	Tursiops truncatus	77.35	0.00e+00	2319.00
IUUC-Vpa-130596	Vicugna pacos	79.18	0.00e+00	1744.00
IUUC-Xtr-132469	Xenopus tropicalis	55.45	0.00e+00	1598.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence