iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020466

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03006556

Gene Name

TRIM25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000017390.3	ENSCAFT00000027553.3	ENSCAFP00000025624.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.40e-07	32.2	13	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C++Cle+fk  p+++pCgH f+  Cl + w     ++ +  +CP Cr
   Q: 13   CSVCLEPFKG-PVTTPCGHNFCGACLdETW----AVQGPPYLCPQCR 54
           ********77.*******************....99999*******8 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAELVPLAEE LSCSVCLEPF KGPVTTPCGH NFCGACLDET WAVQGPPYLC PQCRAVYQAR 60
PQLHKNTVLC AVVEQLLQAG AAPQPPDGGT PAAPAKTGPV ACDHCLKAPA VKTCMVCMAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGAGCGCCG CGGGCCCGCC CTGCCGCTCG CTGGTTTCGT TTCCTCGGCC TGGGGGGTGG 60
GGCGCCAGTG TCGCCCCGAG CCCGCGCGTC CCAGCGCGTC CCGTCCGGCC GCCGAGCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00097--zf-C3HC4

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

KEGG

cfa:491103

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	78.56	0.00e+00	1007.00
IUUC-Apl-004101	Anas platyrhynchos	49.28	4.00e-170	591.00
IUUC-Aca-005025	Anolis carolinensis	48.12	4.00e-176	611.00
IUUC-Bta-012735	Bos taurus	72.53	0.00e+00	921.00
IUUC-Cja-019996	Callithrix jacchus	67.02	2.00e-166	578.00
IUUC-Cpo-021737	Cavia porcellus	65.83	0.00e+00	826.00
IUUC-Csa-023217	Chlorocebus sabaeus	75.98	0.00e+00	954.00
IUUC-Cho-024346	Choloepus hoffmanni	47.96	5.00e-67	248.00
IUUC-Dno-030082	Dasypus novemcinctus	71.68	0.00e+00	911.00
IUUC-Dor-030335	Dipodomys ordii	49.41	2.00e-118	419.00
IUUC-Ete-032923	Echinops telfairi	66.95	0.00e+00	763.00
IUUC-Eca-033411	Equus caballus	72.00	0.00e+00	933.00
IUUC-Eeu-034656	Erinaceus europaeus	68.00	4.00e-153	535.00
IUUC-Fca-035371	Felis catus	81.50	0.00e+00	1045.00
IUUC-Fal-037008	Ficedula albicollis	46.35	5.00e-159	554.00
IUUC-Gmo-038668	Gadus morhua	33.71	1.00e-102	367.00
IUUC-Gga-040608	Gallus gallus	47.43	2.00e-162	566.00
IUUC-Gac-041409	Gasterosteus aculeatus	34.25	5.00e-111	395.00
IUUC-Ggo-044518	Gorilla gorilla	75.59	0.00e+00	934.00
IUUC-Hsa-045828	Homo sapiens	76.14	0.00e+00	956.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	66.16	6.00e-127	447.00
IUUC-Lch-050478	Latimeria chalumnae	38.46	3.00e-73	269.00
IUUC-Loc-052864	Lepisosteus oculatus	35.94	1.00e-111	397.00
IUUC-Laf-054325	Loxodonta africana	72.28	5.00e-157	546.00
IUUC-Mcc-054920	Macaca mulatta	76.45	0.00e+00	957.00
IUUC-Meu-056367	Macropus eugenii	71.43	2.00e-73	270.00
IUUC-Mga-059975	Meleagris gallopavo	49.21	3.00e-167	582.00
IUUC-Mmr-060748	Microcebus murinus	72.71	0.00e+00	912.00
IUUC-Mdo-062904	Monodelphis domestica	57.41	0.00e+00	688.00
IUUC-Mmu-063891	Mus musculus	69.03	0.00e+00	885.00
IUUC-Mpu-066473	Mustela putorius furo	79.81	0.00e+00	1029.00
IUUC-Mlu-068185	Myotis lucifugus	71.59	0.00e+00	893.00
IUUC-Nle-070177	Nomascus leucogenys	75.63	0.00e+00	956.00
IUUC-Opr-070558	Ochotona princeps	56.95	3.00e-138	484.00
IUUC-Ont-071368	Oreochromis niloticus	34.54	2.00e-108	386.00
IUUC-Ocu-074461	Oryctolagus cuniculus	65.70	2.00e-145	508.00
IUUC-Ola-086503	Oryzias latipes	27.88	5.00e-57	215.00
IUUC-Oga-088937	Otolemur garnettii	66.82	0.00e+00	837.00
IUUC-Oar-089781	Ovis aries	70.59	2.00e-178	618.00
IUUC-Ptr-090771	Pan troglodytes	76.45	0.00e+00	944.00
IUUC-Pan-092830	Papio anubis	76.45	0.00e+00	956.00
IUUC-Psi-093664	Pelodiscus sinensis	52.23	7.00e-179	620.00
IUUC-Pma-094147	Petromyzon marinus	26.17	6.00e-61	228.00
IUUC-Pfo-096528	Poecilia formosa	34.84	4.00e-113	402.00
IUUC-Pab-097588	Pongo abelii	76.14	0.00e+00	953.00
IUUC-Pca-100890	Procavia capensis	67.30	0.00e+00	836.00
IUUC-Pva-102314	Pteropus vampyrus	75.04	0.00e+00	927.00
IUUC-Rno-105234	Rattus norvegicus	66.92	0.00e+00	863.00
IUUC-Sce-106362	Saccharomyces cerevisiae	38.46	2.00e-08	53.50
IUUC-Sha-106807	Sarcophilus harrisii	53.90	0.00e+00	664.00
IUUC-Sar-113283	Sorex araneus	54.17	3.00e-126	445.00
IUUC-Ssc-115878	Sus scrofa	76.07	5.00e-102	363.00
IUUC-Tgu-117026	Taeniopygia guttata	43.96	1.00e-126	446.00
IUUC-Tru-117794	Takifugu rubripes	34.00	2.00e-100	359.00
IUUC-Tbe-127580	Tupaia belangeri	66.40	8.00e-140	489.00
IUUC-Ttr-128648	Tursiops truncatus	71.25	0.00e+00	627.00
IUUC-Vpa-130254	Vicugna pacos	85.23	1.00e-92	333.00
IUUC-Xtr-132892	Xenopus tropicalis	41.91	4.00e-72	265.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence