iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120525

UUCD1 version

UUC-TeN-00054

Ensembl Protein ID

ENSTNIP00000007425.1

UniProt Accession

H3CGP7; H3CGP7_TETNG

Protein Name

Uncharacterized protein

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000004769.1	ENSTNIT00000007583.1	ENSTNIP00000007425.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.00e-19	69.9	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-06	27.3	148	172

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  gg+ f++h++vLaa+S++F+a+f ++l+es     v+++d v pev++ ll+F Y++++ +ne
   Q: 46   TDVTLRAGGRSFPCHRAVLAACSQYFQAMFGGGLRESL-DQDVDFRDsVHPEVLELLLDFAYSSRVVINE 114
           7************************************9.99*****99*****************99887 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 3    NclgilrfAdlydcpdLkdaaldfi 27
           Nclg++ +Ad+++c +L++   +++
   Q: 148  NCLGMMLLADAHQCKRLYELSWRMC 172
           ******************9776666 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MSLTVHENRK SRASLGSATG SPFHQPSHPD RVLSHLDAMR KQRVLTDVTL RAGGRSFPCH 60
RAVLAACSQY FQAMFGGGLR ESLDQDVDFR DSVHPEVLEL LLDFAYSSRV VINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCTGA CCGTCCACGA GAACCGTAAG TCCCGCGCCA GCCTGGGGTC GGCCACCGGG 60
TCCCCGTTCC ACCAGCCCTC CCACCCCGAC CGCGTCCTGT CCCACCTGGA CGCCATGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	76.14	0.00e+00	936.00
IUUC-Apl-003543	Anas platyrhynchos	76.52	0.00e+00	911.00
IUUC-Aca-004729	Anolis carolinensis	74.32	0.00e+00	896.00
IUUC-Ame-011020	Astyanax mexicanus	82.74	0.00e+00	974.00
IUUC-Bta-012955	Bos taurus	75.80	0.00e+00	933.00
IUUC-Cja-018839	Callithrix jacchus	75.47	0.00e+00	931.00
IUUC-Cfa-020224	Canis familiaris	76.31	0.00e+00	942.00
IUUC-Cpo-021593	Cavia porcellus	75.80	0.00e+00	894.00
IUUC-Cre-022832	Chlamydomonas reinhardtii	35.04	1.00e-12	66.60
IUUC-Csa-023276	Chlorocebus sabaeus	75.80	0.00e+00	936.00
IUUC-Dre-028053	Danio rerio	83.25	0.00e+00	951.00
IUUC-Dno-029287	Dasypus novemcinctus	75.47	0.00e+00	924.00
IUUC-Fca-035897	Felis catus	76.14	0.00e+00	934.00
IUUC-Fal-037036	Ficedula albicollis	77.16	0.00e+00	924.00
IUUC-Gmo-039345	Gadus morhua	83.59	0.00e+00	942.00
IUUC-Gga-040404	Gallus gallus	76.65	0.00e+00	918.00
IUUC-Gac-042447	Gasterosteus aculeatus	85.11	0.00e+00	969.00
IUUC-Ggo-045060	Gorilla gorilla	75.80	0.00e+00	935.00
IUUC-Hsa-046494	Homo sapiens	75.80	0.00e+00	934.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	76.31	0.00e+00	941.00
IUUC-Lch-050211	Latimeria chalumnae	77.83	0.00e+00	934.00
IUUC-Loc-052578	Lepisosteus oculatus	82.06	0.00e+00	971.00
IUUC-Laf-053498	Loxodonta africana	75.80	0.00e+00	897.00
IUUC-Mcc-055033	Macaca mulatta	75.97	0.00e+00	937.00
IUUC-Meu-056893	Macropus eugenii	77.33	0.00e+00	947.00
IUUC-Mga-060025	Meleagris gallopavo	76.65	0.00e+00	917.00
IUUC-Mmr-060658	Microcebus murinus	75.80	0.00e+00	933.00
IUUC-Mdo-062667	Monodelphis domestica	77.33	0.00e+00	951.00
IUUC-Mmu-063125	Mus musculus	74.28	0.00e+00	880.00
IUUC-Mpu-066209	Mustela putorius furo	75.97	0.00e+00	936.00
IUUC-Mlu-068237	Myotis lucifugus	75.30	0.00e+00	892.00
IUUC-Nle-069454	Nomascus leucogenys	75.73	0.00e+00	922.00
IUUC-Ont-072138	Oreochromis niloticus	84.94	0.00e+00	955.00
IUUC-Oan-073320	Ornithorhynchus anatinus	75.47	0.00e+00	920.00
IUUC-Ocu-073765	Oryctolagus cuniculus	75.63	0.00e+00	900.00
IUUC-Oga-088002	Otolemur garnettii	75.97	0.00e+00	932.00
IUUC-Oar-089481	Ovis aries	75.80	0.00e+00	932.00
IUUC-Ptr-091200	Pan troglodytes	75.63	0.00e+00	931.00
IUUC-Psi-093884	Pelodiscus sinensis	76.31	0.00e+00	909.00
IUUC-Pva-102321	Pteropus vampyrus	75.13	0.00e+00	929.00
IUUC-Rno-104835	Rattus norvegicus	74.28	0.00e+00	881.00
IUUC-Sha-107528	Sarcophilus harrisii	76.65	0.00e+00	942.00
IUUC-Ssc-116161	Sus scrofa	76.31	0.00e+00	937.00
IUUC-Tgu-116569	Taeniopygia guttata	77.16	0.00e+00	925.00
IUUC-Ttr-129297	Tursiops truncatus	76.31	0.00e+00	937.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence