iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000060860.8	ENSMUST00000205815.1	ENSMUSP00000146232.1
ENSMUSG00000060860.8	ENSMUST00000079496.8	ENSMUSP00000078459.7
ENSMUSG00000060860.8	ENSMUST00000205885.1	ENSMUSP00000146213.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
RAID2
Post-translational Modifications (PTMs)
mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.50e-40	138.1	17	149

Active Site

Position(s)	Description	Evidence
95	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 3    kkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeek 91
           +ke+++l++dpp+gi++ p++e dlt+++v+i+Gpe+tpY+gg+F++++ + +d+P++PPk  fltkifhPnv +nG++C+++lk  ++
   Q: 17   YKEVTTLTADPPDGIKVFPNEE-DLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKGYFLTKIFHPNVGPNGEICVNVLK--RD 102
           79********************.9************************************************************9..** PP
   S: 92   Wspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           W++ l +++vll+i+ ll +pnpes+lneea +ll +n eey  ++r
   Q: 103  WTAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLLENYEEYAARAR 149
           ******************************************99876 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MNSNVENLPP HIIRLVYKEV TTLTADPPDG IKVFPNEEDL TDLQVTIEGP EGTPYAGGLF 60
RMKLLLGKDF PASPPKGYFL TKIFHPNVGP NGEICVNVLK RDWTAELGIR HVLLTIKCLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCTAGGTT TTTAGCCGCT TGGTTCTCCC AGGTCAACTC CTCAGCCGGC GTGAGCCCTC 60
ATTGTGATAG CACTCCTCAC AAACTGGGTT CGAACTTCTG CTACTATTCT GACAAGAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000818	Aegilops tauschii	59.41	5.00e-48	184.00
IUUC-Aml-001979	Ailuropoda melanoleuca	98.71	3.00e-87	314.00
IUUC-Atr-002706	Amborella trichopoda	64.24	4.00e-47	181.00
IUUC-Aca-004432	Anolis carolinensis	79.10	6.00e-87	313.00
IUUC-Aly-005779	Arabidopsis lyrata	64.10	3.00e-57	214.00
IUUC-Ath-007162	Arabidopsis thaliana	64.74	2.00e-57	215.00
IUUC-Acl-008107	Aspergillus clavatus	50.40	6.00e-33	135.00
IUUC-Afl-008578	Aspergillus flavus	56.88	2.00e-33	136.00
IUUC-Afu-009034	Aspergillus fumigatus	52.34	9.00e-34	137.00
IUUC-Ani-009151	Aspergillus nidulans	51.94	6.00e-35	142.00
IUUC-Ang-009649	Aspergillus niger	50.77	4.00e-35	142.00
IUUC-Ame-010836	Astyanax mexicanus	77.19	2.00e-76	278.00
IUUC-Bta-012740	Bos taurus	99.35	4.00e-88	317.00
IUUC-Bdi-014057	Brachypodium distachyon	64.24	6.00e-48	183.00
IUUC-Bol-016481	Brassica oleracea	65.38	2.00e-57	215.00
IUUC-Bra-016867	Brassica rapa	64.74	2.00e-57	216.00
IUUC-Cja-019763	Callithrix jacchus	91.54	1.00e-92	332.00
IUUC-Cfa-020216	Canis familiaris	91.95	3.00e-88	317.00
IUUC-Cpo-021720	Cavia porcellus	94.15	1.00e-89	322.00
IUUC-Cre-022676	Chlamydomonas reinhardtii	60.93	2.00e-55	207.00
IUUC-Csa-023751	Chlorocebus sabaeus	92.04	6.00e-93	333.00
IUUC-Cho-024620	Choloepus hoffmanni	97.35	4.00e-62	229.00
IUUC-Cin-025632	Ciona intestinalis	57.28	9.00e-65	239.00
IUUC-Csv-025984	Ciona savignyi	66.03	3.00e-62	231.00
IUUC-Cne-026844	Cryptococcus neoformans	53.69	4.00e-47	181.00
IUUC-Cme-027294	Cyanidioschyzon merolae	54.07	1.00e-50	192.00
IUUC-Dre-027674	Danio rerio	76.02	7.00e-76	276.00
IUUC-Dno-029886	Dasypus novemcinctus	99.35	4.00e-88	317.00
IUUC-Dor-030440	Dipodomys ordii	92.04	3.00e-100	357.00
IUUC-Dse-031211	Dothistroma septosporum	47.90	1.00e-31	128.00
IUUC-Dme-031888	Drosophila melanogaster	66.88	8.00e-62	229.00
IUUC-Ete-032365	Echinops telfairi	85.53	2.00e-60	224.00
IUUC-Eca-033733	Equus caballus	89.55	1.00e-88	318.00
IUUC-Eeu-035342	Erinaceus europaeus	97.40	7.00e-86	309.00
IUUC-Fca-035964	Felis catus	98.20	1.00e-61	229.00
IUUC-Gmo-039357	Gadus morhua	79.75	1.00e-74	272.00
IUUC-Gga-040261	Gallus gallus	78.70	2.00e-47	181.00
IUUC-Gac-042593	Gasterosteus aculeatus	76.61	2.00e-76	278.00
IUUC-Gma-042876	Glycine max	63.58	3.00e-56	211.00
IUUC-Ggo-044626	Gorilla gorilla	90.13	3.00e-64	237.00
IUUC-Hsa-046058	Homo sapiens	92.54	2.00e-93	334.00
IUUC-Hvu-047281	Hordeum vulgare	64.24	3.00e-48	184.00
IUUC-Itr-048739	Ictidomys tridecemlineatus	88.06	5.00e-95	340.00
IUUC-Lch-049415	Latimeria chalumnae	71.07	6.00e-58	216.00
IUUC-Lpe-050956	Leersia perrieri	51.66	3.00e-32	131.00
IUUC-Lma-052996	Leptosphaeria maculans	52.29	3.00e-31	129.00
IUUC-Laf-053337	Loxodonta africana	90.55	3.00e-87	314.00
IUUC-Mcc-055485	Macaca mulatta	82.30	1.00e-89	322.00
IUUC-Meu-056123	Macropus eugenii	96.75	3.00e-85	307.00
IUUC-Mtr-058300	Medicago truncatula	63.58	4.00e-55	207.00
IUUC-Mla-059060	Melampsora laricipopulina	53.95	1.00e-49	189.00
IUUC-Mmr-061005	Microcebus murinus	99.35	2.00e-88	318.00
IUUC-Mdo-062979	Monodelphis domestica	96.80	4.00e-68	250.00
IUUC-Mac-065490	Musa acuminata	64.90	1.00e-47	183.00
IUUC-Mpu-065829	Mustela putorius furo	94.77	3.00e-92	330.00
IUUC-Mlu-067498	Myotis lucifugus	94.81	2.00e-79	288.00
IUUC-Nfi-068520	Neosartorya fischeri	52.34	1.00e-33	137.00
IUUC-Nle-069727	Nomascus leucogenys	92.54	4.00e-94	337.00
IUUC-Opr-071066	Ochotona princeps	97.37	4.00e-62	229.00
IUUC-Ont-072363	Oreochromis niloticus	75.58	4.00e-74	270.00
IUUC-Oan-073383	Ornithorhynchus anatinus	92.59	2.00e-55	207.00
IUUC-Ocu-074599	Oryctolagus cuniculus	97.74	7.00e-74	269.00
IUUC-Oba-075186	Oryza barthii	64.90	6.00e-50	191.00
IUUC-Obr-076104	Oryza brachyantha	64.90	3.00e-48	184.00
IUUC-Ogl-077835	Oryza glaberrima	64.90	5.00e-50	190.00
IUUC-Ogu-078690	Oryza glumaepatula	64.90	5.00e-50	190.00
IUUC-Oin-080215	Oryza indica	64.90	6.00e-50	191.00
IUUC-Olo-080816	Oryza longistaminata	64.90	5.00e-50	191.00
IUUC-Ome-081657	Oryza meridionalis	64.90	1.00e-49	189.00
IUUC-Oni-082601	Oryza nivara	64.90	4.00e-50	191.00
IUUC-Opu-083367	Oryza punctata	65.56	1.00e-49	189.00
IUUC-Oru-084477	Oryza rufipogon	64.90	4.00e-50	191.00
IUUC-Osa-086119	Oryza sativa	64.90	5.00e-50	191.00
IUUC-Ola-086702	Oryzias latipes	76.61	2.00e-76	278.00
IUUC-Olu-087576	Ostreococcus lucimarinus	55.26	1.00e-47	182.00
IUUC-Oga-088946	Otolemur garnettii	95.83	6.00e-90	323.00
IUUC-Oar-089564	Ovis aries	97.59	6.00e-92	329.00
IUUC-Ptr-090620	Pan troglodytes	92.50	7.00e-93	333.00
IUUC-Pan-092382	Papio anubis	82.30	1.00e-89	322.00
IUUC-Psi-093891	Pelodiscus sinensis	88.60	3.00e-59	219.00
IUUC-Pma-094344	Petromyzon marinus	82.35	5.00e-74	270.00
IUUC-Ppa-095452	Physcomitrella patens	60.00	4.00e-46	177.00
IUUC-Pfo-097288	Poecilia formosa	77.78	6.00e-77	280.00
IUUC-Pab-098506	Pongo abelii	92.04	6.00e-93	333.00
IUUC-Pop-098882	Populus trichocarpa	62.91	3.00e-56	211.00
IUUC-Pca-100749	Procavia capensis	92.54	5.00e-97	347.00
IUUC-Ppe-102084	Prunus persica	63.58	3.00e-56	211.00
IUUC-Pva-102755	Pteropus vampyrus	92.04	2.00e-97	347.00
IUUC-Pgr-103394	Puccinia graminis	54.61	3.00e-48	185.00
IUUC-Ptt-103750	Puccinia triticina	54.61	3.00e-48	185.00
IUUC-Pte-104240	Pyrenophora teres	48.46	5.00e-30	125.00
IUUC-Pyt-104483	Pyrenophora triticirepentis	47.69	2.00e-29	124.00
IUUC-Rno-105739	Rattus norvegicus	98.01	2.00e-114	404.00
IUUC-Smo-108939	Selaginella moellendorffii	55.69	2.00e-45	175.00
IUUC-Sit-109881	Setaria italica	64.90	9.00e-49	186.00
IUUC-Sly-111764	Solanum lycopersicum	62.25	3.00e-56	211.00
IUUC-Stu-111968	Solanum tuberosum	62.25	3.00e-56	211.00
IUUC-Sar-113093	Sorex araneus	62.87	1.00e-58	219.00
IUUC-Sbi-113842	Sorghum bicolor	65.56	2.00e-48	186.00
IUUC-Sre-115036	Sporisorium reilianum	42.42	6.00e-33	133.00
IUUC-Tru-117716	Takifugu rubripes	78.36	7.00e-77	280.00
IUUC-Tni-120210	Tetraodon nigroviridis	77.78	2.00e-76	278.00
IUUC-Tca-121315	Theobroma cacao	63.58	1.00e-56	213.00
IUUC-Tae-124051	Triticum aestivum	59.41	3.00e-48	184.00
IUUC-Tur-126669	Triticum urartu	63.58	6.00e-48	184.00
IUUC-Tme-127125	Tuber melanosporum	46.24	3.00e-39	155.00
IUUC-Tbe-128157	Tupaia belangeri	98.70	3.00e-87	314.00
IUUC-Ttr-128593	Tursiops truncatus	92.54	4.00e-100	357.00
IUUC-Uma-129592	Ustilago maydis	48.99	1.00e-39	155.00
IUUC-Vvi-131716	Vitis vinifera	62.91	1.00e-56	213.00
IUUC-Xtr-132592	Xenopus tropicalis	76.12	1.00e-83	301.00
IUUC-Xma-133064	Xiphophorus maculatus	74.71	2.00e-68	252.00
IUUC-Yli-134575	Yarrowia lipolytica	50.00	5.00e-38	150.00
IUUC-Zma-135328	Zea mays	63.58	2.00e-48	185.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence