iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-068179

Ensembl Protein ID

ENSMLUP00000002546.1

UniProt Accession

G1NYP5; G1NYP5_MYOLU

Genbank Protein ID

ENSMLUP00000002546

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02007190

Gene Name

STRAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000002797.1	ENSMLUT00000002796.1	ENSMLUP00000002546.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-26	91.6	263	294
UBD/Beta-Prp	5.10e-40	137.5	12	294

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtll.vsGsdDgtikvWDl 30
           gH ++++c++f +d+ l +sGs Dgt+++W +
   Q: 263  GHFGPIHCVRFsPDGELyASGSEDGTLRLWQT 294
           799*********997776************85 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkf...spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           gh   ++ +++f   +p + +l+++++dg+  + + +tg+ + ++ gh+++v+  ++++d+   +t++ D t+kvwd  +g+ ++tl  
   Q: 12   GHTR-PVVDLAFsgiTPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLA- 98
           4444.5555888888899999*******************************************************************. PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           h++ v s++f +++++l+++++d+ +r++dl++ +   +  sgh++ +  + + ++++ + s ++D+tvrlWd +t++ ++ l+   + 
   Q: 99   HKHIVKSVDFTQDSNYLLTAGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVRLWDHATMTEVKSLSF--NM 184
           **************************************9**************998877766.69*********99999999964..89 PP
   S: 182  svyslsfdsng........................................kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrf 230
           sv s+++ ++g                                        ++lv+g++d ++  +d+ +ge +++++gh  ++ +vrf
   Q: 185  SVSSMEYIPEGeilvitygrsiafhsavsleliksfetpatinsaslhpekEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRF 273
           999999777777777777777777777777777777777777777777777************************************** PP
   S: 231  spnderlvsgssDgsiriWdl 251
           sp++e+++sgs+Dg++r+W +
   Q: 274  SPDGELYASGSEDGTLRLWQT 294
           *******************65 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MAMRQTPLTC SGHTRPVVDL AFSGITPYGY FLISACKDGK PMLRQGDTGD WIGTFLGHKG 60
AVWGATLNKD ATKAATAAAD FTAKVWDAVS GDELMTLAHK HIVKSVDFTQ DSNYLLTAGQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGATGA GGCAGACTCC GCTCACCTGC TCCGGCCACA CGCGGCCCGT GGTGGACCTG 60
GCCTTCAGCG GCATCACGCC GTACGGCTAT TTCTTAATCA GCGCGTGCAA AGGTGAGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0032797--C:SMN complex
GO:0034719--C:SMN-Sm protein complex
GO:0003723--F:RNA binding
GO:0030277--P:maintenance of gastrointestinal epithelium
GO:0010633--P:negative regulation of epithelial cell migration
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0060394--P:negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000668	Aegilops tauschii	50.17	2.00e-76	279.00
IUUC-Aml-002091	Ailuropoda melanoleuca	94.51	0.00e+00	641.00
IUUC-Atr-002571	Amborella trichopoda	51.55	6.00e-79	287.00
IUUC-Apl-003327	Anas platyrhynchos	86.08	9.00e-147	512.00
IUUC-Aca-005324	Anolis carolinensis	87.14	3.00e-167	580.00
IUUC-Aly-006452	Arabidopsis lyrata	50.00	5.00e-78	284.00
IUUC-Ath-006646	Arabidopsis thaliana	50.00	4.00e-78	284.00
IUUC-Acl-008014	Aspergillus clavatus	40.72	3.00e-49	188.00
IUUC-Afl-008701	Aspergillus flavus	40.07	9.00e-34	137.00
IUUC-Afu-008942	Aspergillus fumigatus	31.38	1.00e-35	143.00
IUUC-Ani-009394	Aspergillus nidulans	41.44	1.00e-49	190.00
IUUC-Ang-009593	Aspergillus niger	38.18	5.00e-36	145.00
IUUC-Aor-010206	Aspergillus oryzae	42.64	3.00e-50	191.00
IUUC-Ame-011328	Astyanax mexicanus	82.75	3.00e-143	501.00
IUUC-Bgr-012308	Blumeria graminis	39.71	2.00e-56	212.00
IUUC-Bta-013429	Bos taurus	97.43	0.00e+00	642.00
IUUC-Bci-013803	Botrytis cinerea	39.77	3.00e-54	205.00
IUUC-Bdi-014996	Brachypodium distachyon	49.30	1.00e-76	280.00
IUUC-Bol-016595	Brassica oleracea	50.34	3.00e-80	291.00
IUUC-Bra-017775	Brassica rapa	49.49	4.00e-79	289.00
IUUC-Cja-018740	Callithrix jacchus	92.29	4.00e-180	623.00
IUUC-Cfa-021145	Canis familiaris	98.00	0.00e+00	644.00
IUUC-Cpo-022373	Cavia porcellus	97.14	0.00e+00	641.00
IUUC-Cre-022806	Chlamydomonas reinhardtii	43.49	6.00e-59	220.00
IUUC-Csa-023098	Chlorocebus sabaeus	96.29	0.00e+00	635.00
IUUC-Cho-024856	Choloepus hoffmanni	88.86	9.00e-161	559.00
IUUC-Cin-025541	Ciona intestinalis	58.06	9.00e-103	366.00
IUUC-Csv-026287	Ciona savignyi	57.44	2.00e-92	331.00
IUUC-Cgl-026513	Colletotrichum gloeosporioides	40.30	7.00e-53	201.00
IUUC-Cne-026869	Cryptococcus neoformans	45.89	2.00e-68	252.00
IUUC-Dre-028457	Danio rerio	76.92	2.00e-149	521.00
IUUC-Dno-029213	Dasypus novemcinctus	97.71	0.00e+00	647.00
IUUC-Dse-031350	Dothistroma septosporum	39.58	7.00e-50	191.00
IUUC-Dme-031857	Drosophila melanogaster	60.69	4.00e-107	380.00
IUUC-Ete-032558	Echinops telfairi	86.82	2.00e-119	421.00
IUUC-Eca-033934	Equus caballus	97.71	0.00e+00	642.00
IUUC-Eeu-034650	Erinaceus europaeus	83.43	5.00e-163	566.00
IUUC-Fca-035909	Felis catus	98.00	0.00e+00	646.00
IUUC-Fal-036706	Ficedula albicollis	86.62	9.00e-143	499.00
IUUC-Fox-037780	Fusarium oxysporum	40.18	1.00e-50	193.00
IUUC-Fso-038197	Fusarium solani	40.60	1.00e-52	199.00
IUUC-Gmo-039707	Gadus morhua	79.29	5.00e-136	476.00
IUUC-Ggr-040054	Gaeumannomyces graminis	39.10	2.00e-53	202.00
IUUC-Gga-040901	Gallus gallus	88.29	3.00e-173	600.00
IUUC-Gac-041876	Gasterosteus aculeatus	73.43	3.00e-142	497.00
IUUC-Gma-044014	Glycine max	50.86	4.00e-79	288.00
IUUC-Ggo-044583	Gorilla gorilla	89.74	3.00e-168	583.00
IUUC-Hsa-046553	Homo sapiens	93.11	0.00e+00	632.00
IUUC-Hvu-047544	Hordeum vulgare	50.69	2.00e-78	286.00
IUUC-Itr-047980	Ictidomys tridecemlineatus	98.29	0.00e+00	652.00
IUUC-Lch-050078	Latimeria chalumnae	82.34	3.00e-157	547.00
IUUC-Lpe-051246	Leersia perrieri	50.86	2.00e-79	289.00
IUUC-Loc-052598	Lepisosteus oculatus	78.92	2.00e-153	535.00
IUUC-Lma-053226	Leptosphaeria maculans	45.22	1.00e-56	213.00
IUUC-Laf-054053	Loxodonta africana	96.57	0.00e+00	643.00
IUUC-Mcc-054652	Macaca mulatta	92.86	0.00e+00	630.00
IUUC-Mor-057256	Magnaporthe oryzae	38.58	2.00e-51	196.00
IUUC-Mpo-057303	Magnaporthe poae	39.47	6.00e-54	204.00
IUUC-Mtr-058421	Medicago truncatula	50.86	5.00e-79	287.00
IUUC-Mla-059073	Melampsora laricipopulina	45.11	2.00e-64	239.00
IUUC-Mga-059664	Meleagris gallopavo	88.03	6.00e-172	596.00
IUUC-Mvi-060534	Microbotryum violaceum	35.09	3.00e-39	155.00
IUUC-Mmr-061044	Microcebus murinus	98.14	3.00e-179	620.00
IUUC-Mdo-063019	Monodelphis domestica	95.43	0.00e+00	633.00
IUUC-Mmu-064092	Mus musculus	97.71	0.00e+00	642.00
IUUC-Mac-065143	Musa acuminata	51.72	3.00e-78	285.00
IUUC-Mpu-066557	Mustela putorius furo	98.29	0.00e+00	652.00
IUUC-Nfi-068553	Neosartorya fischeri	40.72	9.00e-49	187.00
IUUC-Ncr-068934	Neurospora crassa	38.24	3.00e-47	182.00
IUUC-Nle-069482	Nomascus leucogenys	92.84	0.00e+00	629.00
IUUC-Opr-071055	Ochotona princeps	76.00	9.00e-131	459.00
IUUC-Ont-072663	Oreochromis niloticus	74.04	2.00e-139	488.00
IUUC-Ocu-074942	Oryctolagus cuniculus	97.71	0.00e+00	642.00
IUUC-Oba-075160	Oryza barthii	50.86	2.00e-79	289.00
IUUC-Obr-076864	Oryza brachyantha	50.86	2.00e-79	288.00
IUUC-Ogl-077076	Oryza glaberrima	50.86	2.00e-79	288.00
IUUC-Ogu-078591	Oryza glumaepatula	50.86	2.00e-79	289.00
IUUC-Oin-079631	Oryza indica	49.66	1.00e-77	283.00
IUUC-Olo-080389	Oryza longistaminata	44.60	3.00e-51	194.00
IUUC-Ome-081693	Oryza meridionalis	49.31	2.00e-76	279.00
IUUC-Oni-082190	Oryza nivara	51.20	1.00e-79	290.00
IUUC-Opu-084163	Oryza punctata	50.86	2.00e-79	289.00
IUUC-Oru-084730	Oryza rufipogon	50.86	2.00e-79	289.00
IUUC-Osa-086010	Oryza sativa	50.86	1.00e-79	289.00
IUUC-Ola-086704	Oryzias latipes	77.49	7.00e-153	533.00
IUUC-Olu-087796	Ostreococcus lucimarinus	51.19	2.00e-79	288.00
IUUC-Oga-088932	Otolemur garnettii	74.58	6.00e-127	446.00
IUUC-Oar-090398	Ovis aries	97.71	0.00e+00	642.00
IUUC-Ptr-091202	Pan troglodytes	96.57	0.00e+00	641.00
IUUC-Pan-091948	Papio anubis	96.57	0.00e+00	639.00
IUUC-Psi-093863	Pelodiscus sinensis	86.69	2.00e-153	534.00
IUUC-Pma-094255	Petromyzon marinus	78.93	5.00e-142	496.00
IUUC-Pno-095075	Phaeosphaeria nodorum	46.01	3.00e-59	221.00
IUUC-Ppa-095169	Physcomitrella patens	50.51	1.00e-80	293.00
IUUC-Pfo-096438	Poecilia formosa	76.92	1.00e-149	522.00
IUUC-Pab-097994	Pongo abelii	96.29	0.00e+00	639.00
IUUC-Pop-099172	Populus trichocarpa	50.00	2.00e-78	285.00
IUUC-Pca-100761	Procavia capensis	86.69	4.00e-153	533.00
IUUC-Ppe-102035	Prunus persica	51.55	4.00e-77	281.00
IUUC-Pva-102794	Pteropus vampyrus	88.86	7.00e-165	573.00
IUUC-Pgr-103581	Puccinia graminis	46.20	3.00e-65	241.00
IUUC-Ptt-103862	Puccinia triticina	46.28	4.00e-63	234.00
IUUC-Pte-104245	Pyrenophora teres	46.01	1.00e-59	223.00
IUUC-Pyt-104537	Pyrenophora triticirepentis	46.01	1.00e-59	223.00
IUUC-Rno-105712	Rattus norvegicus	98.00	0.00e+00	644.00
IUUC-Sha-107568	Sarcophilus harrisii	94.57	0.00e+00	627.00
IUUC-Ssl-108655	Sclerotinia sclerotiorum	38.89	2.00e-52	199.00
IUUC-Smo-108784	Selaginella moellendorffii	53.08	8.00e-83	300.00
IUUC-Sit-109807	Setaria italica	52.07	2.00e-80	293.00
IUUC-Sly-111555	Solanum lycopersicum	51.38	3.00e-78	285.00
IUUC-Stu-111953	Solanum tuberosum	50.69	1.00e-77	283.00
IUUC-Sar-113491	Sorex araneus	86.25	2.00e-118	418.00
IUUC-Sbi-114290	Sorghum bicolor	51.72	1.00e-80	292.00
IUUC-Sre-115008	Sporisorium reilianum	43.40	3.00e-64	238.00
IUUC-Ssc-116392	Sus scrofa	93.39	0.00e+00	629.00
IUUC-Tgu-116835	Taeniopygia guttata	86.67	1.00e-144	505.00
IUUC-Tru-117558	Takifugu rubripes	76.14	7.00e-150	523.00
IUUC-Tsy-119522	Tarsius syrichta	94.57	5.00e-174	603.00
IUUC-Tni-120330	Tetraodon nigroviridis	80.94	1.00e-141	495.00
IUUC-Tca-121759	Theobroma cacao	51.55	2.00e-78	285.00
IUUC-Tre-122163	Trichoderma reesei	40.90	9.00e-52	197.00
IUUC-Tvi-122609	Trichoderma virens	42.34	8.00e-53	200.00
IUUC-Tae-123053	Triticum aestivum	50.34	6.00e-78	284.00
IUUC-Tur-126808	Triticum urartu	47.29	1.00e-63	236.00
IUUC-Tme-127137	Tuber melanosporum	47.40	2.00e-68	252.00
IUUC-Tbe-127324	Tupaia belangeri	84.65	1.00e-94	339.00
IUUC-Ttr-128202	Tursiops truncatus	97.43	0.00e+00	638.00
IUUC-Uma-129433	Ustilago maydis	44.03	6.00e-64	237.00
IUUC-Vda-129675	Verticillium dahliae	38.94	3.00e-52	198.00
IUUC-Vpa-130382	Vicugna pacos	98.00	0.00e+00	644.00
IUUC-Vvi-131432	Vitis vinifera	51.89	1.00e-81	296.00
IUUC-Xtr-132648	Xenopus tropicalis	72.19	8.00e-135	473.00
IUUC-Xma-133969	Xiphophorus maculatus	73.50	5.00e-141	493.00
IUUC-Yli-134670	Yarrowia lipolytica	34.84	4.00e-45	174.00
IUUC-Zma-135878	Zea mays	51.72	1.00e-80	293.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence