iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097542

Ensembl Protein ID

ENSPPYP00000005615.2

UniProt Accession

H2NIJ4; H2NIJ4_PONAB

Genbank Protein ID

ENSPPYP00000005615

Protein Name

Coronin

Genbank Nucleotide ID

ABGA01248299

Gene Name

CORO1C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000004923.2	ENSPPYT00000005831.2	ENSPPYP00000005615.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.10e-16	57.8	78	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 78   GHTGPVLDIDWcphNDQVIASGSEDCTVMVWQI 110
           8***********977799*************86 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MRRVVRQSKF RHVFGQAVKN DQCYDDIRVS RVTWDSSFCA VNPRFVAIII EASGGGAFLV 60
LPLHKTGRID KSYPTVCGHT GPVLDIDWCP HNDQVIASGS EDCTVMVWQI PENGLTLSLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGGCGGCT GCCCGCGCCC CTCCCCCGCA CGGCGCTTAG TGCCAGGCGG GAGGCGGCAG 60
CGGTCGGACG CTTCGCCCGG CTTTGCAGCG GGGACTTCGG CGGCGGCGCC TCAGGCACCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027333--CORO1C
IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0016600--C:flotillin complex
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0016328--C:lateral plasma membrane
GO:0031982--C:vesicle
GO:0030036--P:actin cytoskeleton organization
GO:0090630--P:activation of GTPase activity
GO:0045184--P:establishment of protein localization
GO:0010633--P:negative regulation of epithelial cell migration
GO:0051895--P:negative regulation of focal adhesion assembly
GO:0044387--P:negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:1900025--P:negative regulation of substrate adhesion-dependent cell spreading
GO:0001755--P:neural crest cell migration
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0010762--P:regulation of fibroblast migration
GO:1900027--P:regulation of ruffle assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002236	Ailuropoda melanoleuca	90.72	0.00e+00	877.00
IUUC-Apl-003861	Anas platyrhynchos	86.47	0.00e+00	843.00
IUUC-Bta-013225	Bos taurus	90.08	0.00e+00	870.00
IUUC-Cja-019948	Callithrix jacchus	90.95	0.00e+00	877.00
IUUC-Cfa-020591	Canis familiaris	90.72	0.00e+00	876.00
IUUC-Cpo-021480	Cavia porcellus	90.51	0.00e+00	876.00
IUUC-Csa-024152	Chlorocebus sabaeus	91.35	0.00e+00	883.00
IUUC-Cho-024687	Choloepus hoffmanni	89.20	0.00e+00	798.00
IUUC-Dno-029552	Dasypus novemcinctus	89.89	0.00e+00	800.00
IUUC-Eca-034118	Equus caballus	89.87	0.00e+00	873.00
IUUC-Fca-035549	Felis catus	90.51	0.00e+00	876.00
IUUC-Fal-037065	Ficedula albicollis	86.26	0.00e+00	847.00
IUUC-Gga-040842	Gallus gallus	86.68	0.00e+00	850.00
IUUC-Ggo-044477	Gorilla gorilla	91.14	0.00e+00	880.00
IUUC-Hsa-046610	Homo sapiens	91.14	0.00e+00	881.00
IUUC-Itr-048583	Ictidomys tridecemlineatus	90.51	0.00e+00	874.00
IUUC-Laf-053416	Loxodonta africana	90.08	0.00e+00	875.00
IUUC-Mcc-055113	Macaca mulatta	91.14	0.00e+00	880.00
IUUC-Meu-056732	Macropus eugenii	73.68	0.00e+00	653.00
IUUC-Mga-060143	Meleagris gallopavo	86.68	0.00e+00	847.00
IUUC-Mmr-061130	Microcebus murinus	90.93	0.00e+00	879.00
IUUC-Mdo-062851	Monodelphis domestica	95.16	0.00e+00	830.00
IUUC-Mmu-063663	Mus musculus	88.82	0.00e+00	860.00
IUUC-Mpu-066179	Mustela putorius furo	90.51	0.00e+00	875.00
IUUC-Mlu-068175	Myotis lucifugus	90.51	0.00e+00	875.00
IUUC-Opr-070617	Ochotona princeps	89.45	0.00e+00	835.00
IUUC-Oan-073547	Ornithorhynchus anatinus	87.08	0.00e+00	847.00
IUUC-Ocu-074569	Oryctolagus cuniculus	88.82	0.00e+00	866.00
IUUC-Oga-089145	Otolemur garnettii	90.72	0.00e+00	878.00
IUUC-Oar-089654	Ovis aries	89.66	0.00e+00	869.00
IUUC-Ptr-090763	Pan troglodytes	91.35	0.00e+00	882.00
IUUC-Pan-091885	Papio anubis	90.83	0.00e+00	840.00
IUUC-Psi-093011	Pelodiscus sinensis	85.62	0.00e+00	837.00
IUUC-Pca-100630	Procavia capensis	74.42	0.00e+00	686.00
IUUC-Rno-105330	Rattus norvegicus	89.66	0.00e+00	868.00
IUUC-Sha-106695	Sarcophilus harrisii	84.88	0.00e+00	671.00
IUUC-Ssc-115348	Sus scrofa	90.30	0.00e+00	874.00
IUUC-Tgu-116597	Taeniopygia guttata	86.47	0.00e+00	843.00
IUUC-Tsy-119223	Tarsius syrichta	79.54	0.00e+00	665.00
IUUC-Tbe-127679	Tupaia belangeri	88.14	0.00e+00	638.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence