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Tag Content
UUCD2 ID IUUC-Sha-107273
UUCD1 version UUC-SaH-00183
Ensembl Protein ID ENSSHAP00000004604.1
UniProt Accession G3VN49; G3VN49_SARHA
Genbank Protein ID ENSSHAP00000004604
Protein Name Uncharacterized protein
Genbank Nucleotide ID AEFK01177033
Gene Name NLE1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSHAG00000004045.1 ENSSHAT00000004652.1 ENSSHAP00000004604.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.30e-66 216.4 197 239
UBD/Beta-Prp 6.10e-78 262.2 105 298
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf......sd.tllvsGsdDgtikvWDlrtgvll 36
           gH+ ++t+l++      ++ ++++s+s Dg+++vWD++ g++ 
   Q: 197  GHSKWITGLSWeplhtnPEcRYVASSSKDGSVRVWDTTIGRCD 239
           8**************998899****************999986 PP
   

   UBD/Beta-Prp
   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
            + +sl+gh+++v +v fsp+gk+l++gs D t++ wdl t ++  t kgh + vls+++sp+g+kl+sG +   i +wd +tg+ l  
   Q: 105  RCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLTTETPHFTSKGHRHWVLSIAWSPDGKKLASGCKNGQILLWDPNTGKQLGR 193
           34899************************************************************************************ PP
   S: 132  tlsghdgvvncvvv.....hpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
            l+gh+++++++++     +p++++++s+s+D+ vr+Wd   g++ r ltg ht+sv+++ +  +g  l s+s+d+t+k+w  + g   
   Q: 194  ALAGHSKWITGLSWeplhtNPECRYVASSSKDGSVRVWDTTIGRCDRILTG-HTQSVTCIRWGGDG-LLYSASQDRTIKVWRAHDGVLC 280
           ***********8762222267889**************************9.************98.********************** PP
   S: 216  rtlnghtdnvksvrfspnde 235
           rtl+gh  +v+ +++s  ++
   Q: 281  RTLQGHAHWVNTMALS--TD 298
           **************99..33 PP
   
Organism Sarcophilus harrisii
Protein Sequence
(Fasta)
MAAEASQDEV RGDVQRLLVQ FQDEGGQLLG SPFDVPVDIT PDKLQLVCNA LLNKEDPLPL 60
AFYVHDSEII TSLEKTLESK SVETEKVLDI IYQPQAVFRV RAITRCTSSL EGHSEAVISV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sha-107273|E3,WD_repeat;UBD,Beta-Prp|Sarcophilus harrisii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAACGTCCCG CCGGGCCACC AGGGGGCAGA GCGCGCTCTC GGCAGCGTGG CCGCGCTATG 60
GAGGCGGCGC TCTAGGCCTC ACGCTTCGTT TCTCTCCACG TGGGGACTCA GGATGGCGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sha-107273|E3,WD_repeat;UBD,Beta-Prp|Sarcophilus harrisii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR012972--NLE
IPR002469--Peptidase_S9B_N
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08154--NLE
PF00400--WD40
PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005730--C:nucleolus
GO:0061484--P:hematopoietic stem cell homeostasis
GO:0001826--P:inner cell mass cell differentiation
GO:0001822--P:kidney development
GO:2001268--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:0045930--P:negative regulation of mitotic cell cycle
GO:0007219--P:Notch signaling pathway
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0042273--P:ribosomal large subunit biogenesis
GO:0048705--P:skeletal system morphogenesis
GO:0001756--P:somitogenesis
KEGG shr:100916826
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000437 Aegilops tauschii 57.94 1.00e-167 582.00
IUUC-Aml-001793 Ailuropoda melanoleuca 91.33 0.00e+00 904.00
IUUC-Atr-002507 Amborella trichopoda 57.77 2.00e-166 578.00
IUUC-Apl-003964 Anas platyrhynchos 83.70 0.00e+00 820.00
IUUC-Aly-006396 Arabidopsis lyrata 55.96 8.00e-164 569.00
IUUC-Ath-007278 Arabidopsis thaliana 55.96 3.00e-163 567.00
IUUC-Ago-007951 Ashbya gossypii 48.39 4.00e-131 461.00
IUUC-Acl-008298 Aspergillus clavatus 48.96 4.00e-122 431.00
IUUC-Afl-008581 Aspergillus flavus 54.90 6.00e-111 393.00
IUUC-Afu-008906 Aspergillus fumigatus 47.39 6.00e-120 424.00
IUUC-Ani-009189 Aspergillus nidulans 45.18 5.00e-118 417.00
IUUC-Ang-009630 Aspergillus niger 51.43 1.00e-123 436.00
IUUC-Aor-010038 Aspergillus oryzae 49.38 6.00e-129 454.00
IUUC-Ate-010278 Aspergillus terreus 48.21 9.00e-125 440.00
IUUC-Ame-011890 Astyanax mexicanus 80.46 0.00e+00 828.00
IUUC-Bgr-012011 Blumeria graminis 47.98 2.00e-131 462.00
IUUC-Bta-012964 Bos taurus 90.06 0.00e+00 899.00
IUUC-Bci-013592 Botrytis cinerea 45.91 8.00e-123 433.00
IUUC-Bdi-015035 Brachypodium distachyon 58.67 4.00e-170 590.00
IUUC-Bol-015501 Brassica oleracea 56.20 3.00e-165 574.00
IUUC-Bra-017642 Brassica rapa 56.20 3.00e-165 574.00
IUUC-Cel-018430 Caenorhabditis elegans 59.10 4.00e-168 584.00
IUUC-Cja-019125 Callithrix jacchus 90.49 0.00e+00 901.00
IUUC-Cfa-021013 Canis familiaris 89.15 0.00e+00 816.00
IUUC-Cpo-021743 Cavia porcellus 88.58 0.00e+00 892.00
IUUC-Cre-022973 Chlamydomonas reinhardtii 46.09 5.00e-116 410.00
IUUC-Csa-024270 Chlorocebus sabaeus 89.81 0.00e+00 904.00
IUUC-Cin-025795 Ciona intestinalis 64.68 0.00e+00 681.00
IUUC-Csv-025953 Ciona savignyi 67.16 0.00e+00 682.00
IUUC-Cgl-026517 Colletotrichum gloeosporioides 51.72 9.00e-108 383.00
IUUC-Cne-026901 Cryptococcus neoformans 49.51 2.00e-139 489.00
IUUC-Cme-027281 Cyanidioschyzon merolae 47.67 1.00e-114 407.00
IUUC-Dre-028515 Danio rerio 76.89 0.00e+00 801.00
IUUC-Dno-029596 Dasypus novemcinctus 91.54 0.00e+00 907.00
IUUC-Dor-030494 Dipodomys ordii 89.23 0.00e+00 899.00
IUUC-Dse-031538 Dothistroma septosporum 50.71 1.00e-134 473.00
IUUC-Dme-031974 Drosophila melanogaster 60.04 2.00e-170 592.00
IUUC-Ete-032948 Echinops telfairi 88.52 5.00e-110 391.00
IUUC-Eca-033399 Equus caballus 90.66 0.00e+00 900.00
IUUC-Eeu-035013 Erinaceus europaeus 89.47 6.00e-110 390.00
IUUC-Fca-035860 Felis catus 90.27 0.00e+00 898.00
IUUC-Fal-037069 Ficedula albicollis 87.25 6.00e-134 469.00
IUUC-Fox-038059 Fusarium oxysporum 46.20 2.00e-125 442.00
IUUC-Fso-038445 Fusarium solani 47.43 1.00e-126 446.00
IUUC-Gmo-039319 Gadus morhua 75.58 0.00e+00 739.00
IUUC-Ggr-040095 Gaeumannomyces graminis 46.88 7.00e-123 434.00
IUUC-Gga-040303 Gallus gallus 86.06 4.00e-133 466.00
IUUC-Gac-042267 Gasterosteus aculeatus 76.79 0.00e+00 759.00
IUUC-Gma-043974 Glycine max 58.06 8.00e-174 603.00
IUUC-Ggo-044637 Gorilla gorilla 90.45 0.00e+00 897.00
IUUC-Hsa-046128 Homo sapiens 89.28 0.00e+00 912.00
IUUC-Hvu-047373 Hordeum vulgare 57.08 5.00e-167 580.00
IUUC-Itr-048070 Ictidomys tridecemlineatus 87.76 0.00e+00 898.00
IUUC-Kpa-049274 Komagataella pastoris 45.75 1.00e-128 453.00
IUUC-Lch-049907 Latimeria chalumnae 83.19 0.00e+00 830.00
IUUC-Lpe-050778 Leersia perrieri 53.46 7.00e-152 530.00
IUUC-Loc-051889 Lepisosteus oculatus 80.46 0.00e+00 833.00
IUUC-Lma-053041 Leptosphaeria maculans 50.23 2.00e-117 416.00
IUUC-Laf-053598 Loxodonta africana 90.17 0.00e+00 905.00
IUUC-Mcc-055660 Macaca mulatta 89.81 0.00e+00 903.00
IUUC-Meu-056197 Macropus eugenii 86.44 0.00e+00 833.00
IUUC-Mor-056949 Magnaporthe oryzae 45.02 1.00e-116 413.00
IUUC-Mpo-057571 Magnaporthe poae 46.44 2.00e-65 243.00
IUUC-Mtr-058530 Medicago truncatula 59.71 9.00e-171 592.00
IUUC-Mla-059133 Melampsora laricipopulina 46.68 6.00e-127 447.00
IUUC-Mga-059252 Meleagris gallopavo 84.93 0.00e+00 671.00
IUUC-Mvi-060522 Microbotryum violaceum 51.11 6.00e-139 487.00
IUUC-Mmr-061117 Microcebus murinus 89.00 0.00e+00 895.00
IUUC-Mdo-062892 Monodelphis domestica 93.61 0.00e+00 946.00
IUUC-Mmu-064108 Mus musculus 89.87 0.00e+00 875.00
IUUC-Mac-064430 Musa acuminata 59.10 8.00e-172 596.00
IUUC-Mpu-065882 Mustela putorius furo 90.51 0.00e+00 899.00
IUUC-Mlu-068123 Myotis lucifugus 90.27 0.00e+00 905.00
IUUC-Nfi-068484 Neosartorya fischeri 48.02 2.00e-121 428.00
IUUC-Ncr-068649 Neurospora crassa 43.69 5.00e-114 404.00
IUUC-Nle-069140 Nomascus leucogenys 90.23 0.00e+00 898.00
IUUC-Opr-070220 Ochotona princeps 82.18 0.00e+00 783.00
IUUC-Ont-072643 Oreochromis niloticus 79.32 0.00e+00 816.00
IUUC-Ocu-074007 Oryctolagus cuniculus 89.85 0.00e+00 874.00
IUUC-Oba-075904 Oryza barthii 58.89 3.00e-171 594.00
IUUC-Obr-076280 Oryza brachyantha 58.67 8.00e-171 593.00
IUUC-Ogl-077425 Oryza glaberrima 58.89 2.00e-171 594.00
IUUC-Ogu-078586 Oryza glumaepatula 58.89 3.00e-171 594.00
IUUC-Oin-079489 Oryza indica 56.96 2.00e-162 565.00
IUUC-Olo-080766 Oryza longistaminata 58.76 7.00e-171 593.00
IUUC-Ome-081905 Oryza meridionalis 59.10 3.00e-171 594.00
IUUC-Oni-083022 Oryza nivara 58.89 2.00e-171 595.00
IUUC-Opu-083615 Oryza punctata 59.10 2.00e-171 594.00
IUUC-Oru-085076 Oryza rufipogon 58.89 2.00e-171 595.00
IUUC-Osa-085744 Oryza sativa 58.89 4.00e-172 597.00
IUUC-Ola-087290 Oryzias latipes 77.43 0.00e+00 803.00
IUUC-Olu-087898 Ostreococcus lucimarinus 52.20 8.00e-144 503.00
IUUC-Oga-088980 Otolemur garnettii 89.81 0.00e+00 893.00
IUUC-Oar-089580 Ovis aries 90.22 0.00e+00 781.00
IUUC-Ptr-090845 Pan troglodytes 90.02 0.00e+00 897.00
IUUC-Pan-092836 Papio anubis 89.07 0.00e+00 909.00
IUUC-Psi-093965 Pelodiscus sinensis 82.05 3.00e-58 216.00
IUUC-Pno-095052 Phaeosphaeria nodorum 48.35 1.00e-123 436.00
IUUC-Ppa-095432 Physcomitrella patens 58.00 4.00e-167 580.00
IUUC-Pfo-096963 Poecilia formosa 70.68 0.00e+00 701.00
IUUC-Pab-097716 Pongo abelii 87.26 0.00e+00 857.00
IUUC-Pop-099224 Populus trichocarpa 59.36 4.00e-174 603.00
IUUC-Pca-100682 Procavia capensis 87.89 0.00e+00 651.00
IUUC-Ppe-101819 Prunus persica 58.74 7.00e-171 593.00
IUUC-Pva-102338 Pteropus vampyrus 88.95 0.00e+00 684.00
IUUC-Pgr-103583 Puccinia graminis 55.23 1.00e-133 469.00
IUUC-Ptt-103737 Puccinia triticina 45.56 5.00e-100 358.00
IUUC-Pte-104150 Pyrenophora teres 54.32 2.00e-123 435.00
IUUC-Pyt-104606 Pyrenophora triticirepentis 54.32 3.00e-123 435.00
IUUC-Rno-105987 Rattus norvegicus 89.41 0.00e+00 891.00
IUUC-Sce-106315 Saccharomyces cerevisiae 47.67 2.00e-129 455.00
IUUC-Sja-107677 Schizosaccharomyces japonicus 47.02 1.00e-121 429.00
IUUC-Spo-108092 Schizosaccharomyces pombe 50.11 3.00e-126 445.00
IUUC-Ssl-108442 Sclerotinia sclerotiorum 43.64 2.00e-116 412.00
IUUC-Smo-108855 Selaginella moellendorffii 55.44 9.00e-162 563.00
IUUC-Sit-110329 Setaria italica 58.89 1.00e-170 593.00
IUUC-Sly-111830 Solanum lycopersicum 60.39 1.00e-174 605.00
IUUC-Stu-112603 Solanum tuberosum 60.39 1.00e-174 605.00
IUUC-Sar-113504 Sorex araneus 85.11 4.00e-69 255.00
IUUC-Sbi-114560 Sorghum bicolor 58.03 3.00e-168 584.00
IUUC-Sre-115133 Sporisorium reilianum 41.40 2.00e-125 442.00
IUUC-Ssc-115903 Sus scrofa 91.33 0.00e+00 902.00
IUUC-Tgu-116798 Taeniopygia guttata 85.41 0.00e+00 866.00
IUUC-Tru-118361 Takifugu rubripes 77.85 0.00e+00 805.00
IUUC-Tsy-118849 Tarsius syrichta 89.73 0.00e+00 897.00
IUUC-Tni-120094 Tetraodon nigroviridis 78.06 0.00e+00 805.00
IUUC-Tca-121634 Theobroma cacao 57.64 2.00e-168 585.00
IUUC-Tre-122051 Trichoderma reesei 46.93 2.00e-121 429.00
IUUC-Tvi-122322 Trichoderma virens 47.66 7.00e-125 440.00
IUUC-Tae-125822 Triticum aestivum 57.82 1.00e-167 582.00
IUUC-Tur-126766 Triticum urartu 51.04 3.00e-159 554.00
IUUC-Tme-127175 Tuber melanosporum 51.79 1.00e-131 463.00
IUUC-Tbe-127779 Tupaia belangeri 89.70 0.00e+00 801.00
IUUC-Ttr-128224 Tursiops truncatus 85.98 0.00e+00 773.00
IUUC-Uma-129537 Ustilago maydis 41.54 2.00e-125 442.00
IUUC-Vda-129927 Verticillium dahliae 46.56 9.00e-114 403.00
IUUC-Vpa-130658 Vicugna pacos 78.94 0.00e+00 758.00
IUUC-Vvi-131659 Vitis vinifera 58.85 4.00e-171 594.00
IUUC-Xtr-132918 Xenopus tropicalis 78.03 0.00e+00 801.00
IUUC-Xma-133700 Xiphophorus maculatus 78.27 0.00e+00 808.00
IUUC-Yli-134478 Yarrowia lipolytica 49.49 1.00e-137 483.00
IUUC-Zma-135835 Zea mays 55.58 4.00e-165 574.00
Created Date 25-Jun-2017

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