iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bgr-012148

Ensembl Protein ID

CCU78357

UniProt Accession

N1JDZ1; N1JDZ1_BLUG1

Genbank Protein ID

CCU78357.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

CAUH01003986

Gene Name

BGHDH14_bgh05132

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
BGHDH14_bgh05132	CCU78357	CCU78357

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.00e-122	406.6	459	790

Active Site

Position(s)	Description	Evidence
759	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllg 102
           + dlkkrl+++f gE+gld+gG++ref++lls+e++np ++lf+ys+ d++tlq+np+sg+ npehl++F+f+Gr++g+a++++r+ld+++  ++yk++l+
   Q: 459  ATDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGI-NPEHLNYFKFIGRVVGLAIFHRRFLDAFFIGALYKMMLN 558
           579*********************************************************9.89************************************* PP
   S: 103  kklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfnevipl 203
           k + l+d+e vd+++++sl+++++n    ie   l+ tfs+++e +g+t+ e+LkpgG++i+Vt  Nk+eYv+ +v++r++++i+eq++af  Gf+e+ip 
   Q: 559  KAVALSDMEGVDADFHRSLQWMLNN---PIEGV-LEQTFSTEDERFGQTTIEDLKPGGRDIEVTDVNKKEYVDMMVKWRIQKRIDEQFQAFITGFHELIPA 655
           ***********************99...89997.******************************************************************* PP
   S: 204  ellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfvirkdasddrlPs 300
           el+++F+e+elelli G +eidved+kk+t y+g yte++++i++Fw+++++++ e+++++LqF+Tg+sr+P++Gf++l+    pr+f+i+k+++ ++lP+
   Q: 656  ELVNVFDERELELLIGGIAEIDVEDWKKHTDYRG-YTESDEVIKFFWQTIRSWDGEQKSRLLQFATGTSRIPVNGFKDLQgsdgPRRFTIEKAGEINNLPK 755
           ********************************76.*********************************************************9999***** PP
   S: 301  snTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           s+TCfn+L+LP+Y+s e+l+ kL++A+eet gF++
   Q: 756  SHTCFNRLDLPPYKSLETLQAKLTMAVEETMGFGQ 790
           *********************************96 PP

Organism

Blumeria graminis

Protein Sequence
(Fasta)

MYTLIVAIEF PDPFAVATLG GEQTKTTSVI KKTLNPYWNE SFDMRANEDS ILAVQIFDQK 60
KFKKKDQGFL GVINVRIGDV LDFSSNQDEM LTRDLKKSTD NLVVHGQLII SLSTNLTEPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTATACAC TAATAGTAGC AATAGAATTT CCGGATCCAT TTGCTGTGGC GACTCTCGGC 60
GGCGAGCAGA CTAAGACGAC GAGCGTCATA AAAAAGACCC TCAATCCCTA CTGGAACGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR024928--E3_ub_ligase_SMURF1
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001201	Ailuropoda melanoleuca	47.20	7.00e-158	550.00
IUUC-Apl-003893	Anas platyrhynchos	42.59	1.00e-149	522.00
IUUC-Aca-005338	Anolis carolinensis	45.48	5.00e-151	526.00
IUUC-Ago-007742	Ashbya gossypii	72.71	0.00e+00	911.00
IUUC-Acl-008273	Aspergillus clavatus	79.56	0.00e+00	990.00
IUUC-Afl-008713	Aspergillus flavus	72.51	0.00e+00	1097.00
IUUC-Afu-009103	Aspergillus fumigatus	71.69	0.00e+00	1096.00
IUUC-Ani-009259	Aspergillus nidulans	72.75	0.00e+00	1105.00
IUUC-Ang-009738	Aspergillus niger	72.24	0.00e+00	1113.00
IUUC-Aor-010053	Aspergillus oryzae	76.92	1.00e-144	503.00
IUUC-Ate-010529	Aspergillus terreus	73.31	0.00e+00	1121.00
IUUC-Ame-010810	Astyanax mexicanus	45.16	5.00e-147	513.00
IUUC-Bta-012679	Bos taurus	46.39	7.00e-152	529.00
IUUC-Bci-013785	Botrytis cinerea	83.08	0.00e+00	1273.00
IUUC-Cel-018299	Caenorhabditis elegans	43.00	1.00e-143	501.00
IUUC-Cja-018732	Callithrix jacchus	46.39	5.00e-152	530.00
IUUC-Cfa-020258	Canis familiaris	47.03	3.00e-156	544.00
IUUC-Cpo-021671	Cavia porcellus	46.39	4.00e-152	530.00
IUUC-Csa-023334	Chlorocebus sabaeus	46.40	5.00e-153	533.00
IUUC-Cho-024695	Choloepus hoffmanni	47.77	5.00e-156	543.00
IUUC-Cin-025212	Ciona intestinalis	44.74	5.00e-149	520.00
IUUC-Csv-026256	Ciona savignyi	45.16	5.00e-145	505.00
IUUC-Cgl-026642	Colletotrichum gloeosporioides	78.23	0.00e+00	1166.00
IUUC-Cne-026849	Cryptococcus neoformans	70.07	0.00e+00	862.00
IUUC-Dre-027770	Danio rerio	45.60	2.00e-147	514.00
IUUC-Dno-029466	Dasypus novemcinctus	46.70	6.00e-152	529.00
IUUC-Dor-030138	Dipodomys ordii	45.90	1.00e-147	514.00
IUUC-Dse-031241	Dothistroma septosporum	73.35	0.00e+00	1130.00
IUUC-Dme-032041	Drosophila melanogaster	44.15	1.00e-139	488.00
IUUC-Ete-032779	Echinops telfairi	44.84	3.00e-137	480.00
IUUC-Eca-033445	Equus caballus	46.39	1.00e-151	528.00
IUUC-Eeu-035247	Erinaceus europaeus	46.12	5.00e-151	526.00
IUUC-Fca-036384	Felis catus	47.04	4.00e-156	544.00
IUUC-Fal-037547	Ficedula albicollis	45.72	2.00e-148	518.00
IUUC-Fox-037774	Fusarium oxysporum	77.12	0.00e+00	1162.00
IUUC-Fso-038393	Fusarium solani	76.86	0.00e+00	1150.00
IUUC-Gmo-039674	Gadus morhua	45.91	6.00e-146	509.00
IUUC-Ggr-040107	Gaeumannomyces graminis	77.12	0.00e+00	1183.00
IUUC-Gga-040524	Gallus gallus	46.75	2.00e-149	521.00
IUUC-Gac-042020	Gasterosteus aculeatus	46.32	1.00e-147	515.00
IUUC-Ggo-045332	Gorilla gorilla	46.39	2.00e-151	528.00
IUUC-Hsa-045968	Homo sapiens	46.39	6.00e-152	529.00
IUUC-Itr-048918	Ictidomys tridecemlineatus	46.75	7.00e-154	536.00
IUUC-Kpa-049273	Komagataella pastoris	66.58	0.00e+00	1002.00
IUUC-Lch-050443	Latimeria chalumnae	45.95	3.00e-150	523.00
IUUC-Loc-052662	Lepisosteus oculatus	45.20	1.00e-143	501.00
IUUC-Lma-052980	Leptosphaeria maculans	71.32	0.00e+00	679.00
IUUC-Laf-053850	Loxodonta africana	46.39	1.00e-151	528.00
IUUC-Mcc-055821	Macaca mulatta	46.39	6.00e-152	529.00
IUUC-Meu-056436	Macropus eugenii	44.76	3.00e-115	407.00
IUUC-Mor-057097	Magnaporthe oryzae	77.46	0.00e+00	1201.00
IUUC-Mpo-057442	Magnaporthe poae	73.62	0.00e+00	1098.00
IUUC-Mla-058996	Melampsora laricipopulina	62.77	0.00e+00	954.00
IUUC-Mga-059362	Meleagris gallopavo	45.96	3.00e-149	520.00
IUUC-Mvi-060395	Microbotryum violaceum	78.12	0.00e+00	815.00
IUUC-Mmr-061061	Microcebus murinus	46.86	3.00e-158	550.00
IUUC-Mdo-062505	Monodelphis domestica	43.55	6.00e-151	526.00
IUUC-Mmu-064136	Mus musculus	46.56	3.00e-152	530.00
IUUC-Mpu-066765	Mustela putorius furo	46.39	1.00e-151	528.00
IUUC-Mlu-067565	Myotis lucifugus	46.39	1.00e-151	528.00
IUUC-Nfi-068427	Neosartorya fischeri	79.90	0.00e+00	992.00
IUUC-Ncr-068918	Neurospora crassa	83.39	0.00e+00	1008.00
IUUC-Nle-069225	Nomascus leucogenys	46.75	1.00e-155	542.00
IUUC-Opr-071044	Ochotona princeps	46.12	7.00e-151	526.00
IUUC-Ont-071822	Oreochromis niloticus	47.26	1.00e-151	528.00
IUUC-Oan-073019	Ornithorhynchus anatinus	45.38	9.00e-146	508.00
IUUC-Ocu-074160	Oryctolagus cuniculus	46.53	4.00e-151	526.00
IUUC-Ola-087467	Oryzias latipes	45.91	3.00e-147	513.00
IUUC-Oga-088460	Otolemur garnettii	46.39	8.00e-152	529.00
IUUC-Oar-090198	Ovis aries	46.45	7.00e-152	529.00
IUUC-Ptr-090939	Pan troglodytes	46.39	6.00e-152	529.00
IUUC-Pan-092284	Papio anubis	46.39	6.00e-152	529.00
IUUC-Psi-093645	Pelodiscus sinensis	46.57	7.00e-151	526.00
IUUC-Pma-094364	Petromyzon marinus	49.80	5.00e-136	475.00
IUUC-Pno-095118	Phaeosphaeria nodorum	71.72	0.00e+00	1125.00
IUUC-Pfo-096171	Poecilia formosa	45.62	3.00e-150	524.00
IUUC-Pab-098088	Pongo abelii	46.39	9.00e-152	529.00
IUUC-Pca-100596	Procavia capensis	48.14	3.00e-134	470.00
IUUC-Pva-102354	Pteropus vampyrus	46.07	4.00e-151	526.00
IUUC-Pgr-103620	Puccinia graminis	77.08	0.00e+00	798.00
IUUC-Ptt-103806	Puccinia triticina	77.51	0.00e+00	681.00
IUUC-Pte-104016	Pyrenophora teres	72.91	0.00e+00	1136.00
IUUC-Pyt-104550	Pyrenophora triticirepentis	72.91	0.00e+00	1136.00
IUUC-Rno-105318	Rattus norvegicus	46.56	5.00e-152	530.00
IUUC-Sce-106289	Saccharomyces cerevisiae	64.82	0.00e+00	990.00
IUUC-Sha-107482	Sarcophilus harrisii	45.56	3.00e-148	517.00
IUUC-Sja-107941	Schizosaccharomyces japonicus	65.95	0.00e+00	999.00
IUUC-Spo-108171	Schizosaccharomyces pombe	65.61	0.00e+00	997.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	83.57	0.00e+00	1261.00
IUUC-Sar-113761	Sorex araneus	46.75	1.00e-152	531.00
IUUC-Sre-114929	Sporisorium reilianum	70.40	0.00e+00	890.00
IUUC-Ssc-115368	Sus scrofa	46.23	3.00e-148	517.00
IUUC-Tgu-117474	Taeniopygia guttata	46.06	6.00e-149	519.00
IUUC-Tru-118442	Takifugu rubripes	47.26	4.00e-154	536.00
IUUC-Tsy-119492	Tarsius syrichta	46.23	2.00e-149	521.00
IUUC-Tni-119993	Tetraodon nigroviridis	46.15	5.00e-146	509.00
IUUC-Tre-122203	Trichoderma reesei	75.91	0.00e+00	1133.00
IUUC-Tvi-122595	Trichoderma virens	75.25	0.00e+00	1144.00
IUUC-Tme-126897	Tuber melanosporum	70.96	0.00e+00	1056.00
IUUC-Tbe-127793	Tupaia belangeri	42.81	3.00e-133	467.00
IUUC-Ttr-128275	Tursiops truncatus	44.79	7.00e-147	512.00
IUUC-Uma-129332	Ustilago maydis	71.07	0.00e+00	860.00
IUUC-Vda-129753	Verticillium dahliae	77.55	0.00e+00	1162.00
IUUC-Vpa-130503	Vicugna pacos	51.03	2.00e-137	482.00
IUUC-Xtr-132859	Xenopus tropicalis	46.45	7.00e-152	529.00
IUUC-Xma-133797	Xiphophorus maculatus	41.21	3.00e-151	527.00
IUUC-Yli-134668	Yarrowia lipolytica	72.08	0.00e+00	932.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence