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Tag Content
UUCD2 ID IUUC-Ocu-074211
UUCD1 version UUC-OrC-00887
Ensembl Protein ID ENSOCUP00000012461.3
UniProt Accession G1T7I4; G1T7I4_RABIT
Genbank Protein ID ENSOCUP00000012461
Protein Name Coatomer subunit alpha
Genbank Nucleotide ID AAGW02000288
Gene Name COPA
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOCUG00000014479.3 ENSOCUT00000014489.3 ENSOCUP00000012461.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.70e-36 122.0 133 163
UBD/Beta-Prp 3.20e-76 256.4 3 324
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH+  v c +f ++ +l+vs+s D t++vWD
   Q: 133  GHNHYVMCAQFhPSeDLVVSASLDQTVRVWD 163
           8***********666**************** PP
   

   UBD/Beta-Prp
   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           t +++++++++ + f+p++++++t+  +g i++wd+++ +l+ ++ +h+++v+ ++f+++++++v+g++D+ ikvw+++ + c+ tl g
   Q: 3    TKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLG 91
           67889999********************************************************************************* PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl............... 166
           h d+++++ f+ +  +++s+s+d+tirvw++++++c+  +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+               
   Q: 92   HLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVC-VLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDIsglrkknlspgaves 179
           **************************************.************************************************** PP
   S: 167  ............ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgs 241
                        t+ ++++  +gh++ v++ +f+++++ +vsg++d++vk+w + +++   v+t++gh +nv++  f+p++e+++s s
   Q: 180  dvrgitgvdlfgTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAweVDTCRGHYNNVSCAVFHPRQELILSNS 268
           ************888888888777********************************888888*************************** PP
   S: 242  sDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           +D+sir+Wd+ +++ ++t+ + +++++  a+ +++ n +++g  d+   ++kl++++p
   Q: 269  EDKSIRVWDMSKRTGVQTFRRDHDRFWVLAA-HPNLNLFAAG-HDGGMIVFKLERERP 324
           *******************************.5554444444.589999999988765 PP
   
Organism Oryctolagus cuniculus
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
Protein Sequence
(Fasta)
MLTKFETKSA RVKGLSFHPK RPWILTSLHN GVIQLWDYRM CTLIDKFDEH DGPVRGIDFH 60
KQQPLFVSGG DDYKIKVWNY KLRRCLFTLL GHLDYIRTTF FHHEYPWILS ASDDQTIRVW 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ocu-074211|E3,WD_repeat;UBD,Beta-Prp|Oryctolagus cuniculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGCTAACCA AATTCGAGAC CAAGAGCGCG CGGGTCAAAG GTAGGGAAGA AGAAAAGGGG 60
AGACGTGGAG GCTGGGTGTC AGAGGCGGCG CTGTTATAGG GGAAGAGAGA ATGGGTGGAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ocu-074211|E3,WD_repeat;UBD,Beta-Prp|Oryctolagus cuniculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR024977--Apc4_WD40_dom
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12894--ANAPC4_WD40
PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0030157--P:pancreatic juice secretion
GO:0016192--P:vesicle-mediated transport
KEGG ocu:100008878
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000064 Aegilops tauschii 53.85 0.00e+00 1321.00
IUUC-Aml-001758 Ailuropoda melanoleuca 98.46 0.00e+00 2495.00
IUUC-Atr-002493 Amborella trichopoda 54.14 0.00e+00 1314.00
IUUC-Apl-003385 Anas platyrhynchos 96.05 0.00e+00 2060.00
IUUC-Aca-005154 Anolis carolinensis 97.10 1.00e-121 427.00
IUUC-Aly-006020 Arabidopsis lyrata 61.83 0.00e+00 1098.00
IUUC-Ath-007058 Arabidopsis thaliana 62.11 0.00e+00 1093.00
IUUC-Ago-007992 Ashbya gossypii 44.72 0.00e+00 1030.00
IUUC-Acl-008027 Aspergillus clavatus 57.09 0.00e+00 1006.00
IUUC-Afl-008644 Aspergillus flavus 49.11 0.00e+00 1187.00
IUUC-Afu-008964 Aspergillus fumigatus 49.07 0.00e+00 1195.00
IUUC-Ani-009379 Aspergillus nidulans 56.48 0.00e+00 1013.00
IUUC-Ang-009756 Aspergillus niger 49.84 0.00e+00 1212.00
IUUC-Aor-010174 Aspergillus oryzae 49.11 0.00e+00 1187.00
IUUC-Ate-010302 Aspergillus terreus 49.47 0.00e+00 1227.00
IUUC-Ame-011229 Astyanax mexicanus 86.76 0.00e+00 2203.00
IUUC-Bgr-012300 Blumeria graminis 48.35 0.00e+00 1142.00
IUUC-Bta-012524 Bos taurus 98.94 0.00e+00 2478.00
IUUC-Bci-013781 Botrytis cinerea 48.46 0.00e+00 1195.00
IUUC-Bdi-014549 Brachypodium distachyon 54.53 0.00e+00 1347.00
IUUC-Bol-015925 Brassica oleracea 61.75 0.00e+00 1085.00
IUUC-Bra-016978 Brassica rapa 61.05 0.00e+00 1080.00
IUUC-Cel-018115 Caenorhabditis elegans 64.27 0.00e+00 1127.00
IUUC-Cja-019107 Callithrix jacchus 96.35 0.00e+00 2435.00
IUUC-Cfa-020675 Canis familiaris 98.35 0.00e+00 2456.00
IUUC-Cpo-021813 Cavia porcellus 99.26 0.00e+00 2501.00
IUUC-Cre-022969 Chlamydomonas reinhardtii 64.68 0.00e+00 1115.00
IUUC-Csa-023523 Chlorocebus sabaeus 99.59 0.00e+00 2520.00
IUUC-Cho-024704 Choloepus hoffmanni 84.44 0.00e+00 1895.00
IUUC-Cin-025572 Ciona intestinalis 72.93 0.00e+00 1884.00
IUUC-Csv-025864 Ciona savignyi 76.09 0.00e+00 1300.00
IUUC-Cgl-026510 Colletotrichum gloeosporioides 57.23 0.00e+00 1024.00
IUUC-Cne-027053 Cryptococcus neoformans 52.06 0.00e+00 1251.00
IUUC-Cme-027222 Cyanidioschyzon merolae 39.62 4.00e-143 502.00
IUUC-Dre-027421 Danio rerio 86.69 0.00e+00 2237.00
IUUC-Dno-029303 Dasypus novemcinctus 98.70 0.00e+00 2491.00
IUUC-Dor-030290 Dipodomys ordii 98.23 0.00e+00 1121.00
IUUC-Dse-031543 Dothistroma septosporum 46.38 0.00e+00 1123.00
IUUC-Dme-031945 Drosophila melanogaster 76.17 0.00e+00 1298.00
IUUC-Ete-032873 Echinops telfairi 92.60 0.00e+00 2153.00
IUUC-Eca-033773 Equus caballus 96.82 0.00e+00 2423.00
IUUC-Eeu-034874 Erinaceus europaeus 84.90 0.00e+00 1497.00
IUUC-Fca-035739 Felis catus 97.80 0.00e+00 2404.00
IUUC-Fal-037263 Ficedula albicollis 88.02 0.00e+00 2133.00
IUUC-Fox-037738 Fusarium oxysporum 48.48 0.00e+00 1215.00
IUUC-Fso-038153 Fusarium solani 48.91 0.00e+00 1206.00
IUUC-Gmo-039602 Gadus morhua 82.48 0.00e+00 2059.00
IUUC-Ggr-039931 Gaeumannomyces graminis 56.32 0.00e+00 1016.00
IUUC-Gga-040590 Gallus gallus 96.90 0.00e+00 2422.00
IUUC-Gac-041318 Gasterosteus aculeatus 86.36 0.00e+00 2216.00
IUUC-Gma-043894 Glycine max 54.98 0.00e+00 1352.00
IUUC-Ggo-045029 Gorilla gorilla 98.70 0.00e+00 2511.00
IUUC-Hsa-046078 Homo sapiens 98.70 0.00e+00 2511.00
IUUC-Hvu-047556 Hordeum vulgare 55.26 0.00e+00 1360.00
IUUC-Itr-048881 Ictidomys tridecemlineatus 98.18 0.00e+00 1745.00
IUUC-Kpa-049256 Komagataella pastoris 45.01 0.00e+00 1084.00
IUUC-Lch-049706 Latimeria chalumnae 93.22 0.00e+00 2324.00
IUUC-Lpe-051316 Leersia perrieri 62.99 0.00e+00 1111.00
IUUC-Loc-051867 Lepisosteus oculatus 72.05 0.00e+00 1221.00
IUUC-Lma-053138 Leptosphaeria maculans 56.43 0.00e+00 1024.00
IUUC-Laf-053510 Loxodonta africana 98.28 0.00e+00 2483.00
IUUC-Mcc-055836 Macaca mulatta 98.46 0.00e+00 2491.00
IUUC-Meu-056238 Macropus eugenii 87.28 0.00e+00 1179.00
IUUC-Mor-057172 Magnaporthe oryzae 48.63 0.00e+00 1197.00
IUUC-Mpo-057300 Magnaporthe poae 48.16 0.00e+00 1185.00
IUUC-Mtr-058248 Medicago truncatula 55.27 0.00e+00 1363.00
IUUC-Mla-059019 Melampsora laricipopulina 52.30 0.00e+00 1291.00
IUUC-Mga-059499 Meleagris gallopavo 96.74 0.00e+00 2416.00
IUUC-Mvi-060336 Microbotryum violaceum 52.96 0.00e+00 1273.00
IUUC-Mmr-061102 Microcebus murinus 98.70 0.00e+00 2461.00
IUUC-Mdo-062594 Monodelphis domestica 97.96 0.00e+00 2516.00
IUUC-Mmu-063736 Mus musculus 97.97 0.00e+00 2481.00
IUUC-Mac-065398 Musa acuminata 52.19 0.00e+00 1240.00
IUUC-Mpu-066701 Mustela putorius furo 98.70 0.00e+00 2449.00
IUUC-Mlu-067392 Myotis lucifugus 97.31 0.00e+00 2454.00
IUUC-Nfi-068270 Neosartorya fischeri 57.45 0.00e+00 1011.00
IUUC-Ncr-068892 Neurospora crassa 49.44 0.00e+00 1186.00
IUUC-Nle-069634 Nomascus leucogenys 99.70 0.00e+00 1381.00
IUUC-Opr-070952 Ochotona princeps 86.69 0.00e+00 1814.00
IUUC-Ont-072488 Oreochromis niloticus 88.48 0.00e+00 2230.00
IUUC-Oba-075761 Oryza barthii 62.87 0.00e+00 1110.00
IUUC-Obr-076429 Oryza brachyantha 62.87 0.00e+00 1110.00
IUUC-Ogl-077364 Oryza glaberrima 62.87 0.00e+00 1111.00
IUUC-Ogu-078257 Oryza glumaepatula 63.13 0.00e+00 1110.00
IUUC-Oin-079274 Oryza indica 62.75 0.00e+00 1109.00
IUUC-Olo-080466 Oryza longistaminata 62.79 0.00e+00 1096.00
IUUC-Ome-081668 Oryza meridionalis 62.55 0.00e+00 935.00
IUUC-Oni-082874 Oryza nivara 63.13 0.00e+00 1110.00
IUUC-Opu-083697 Oryza punctata 53.96 0.00e+00 1331.00
IUUC-Oru-084274 Oryza rufipogon 62.87 0.00e+00 1111.00
IUUC-Osa-085565 Oryza sativa 62.87 0.00e+00 1111.00
IUUC-Ola-086921 Oryzias latipes 86.96 0.00e+00 2206.00
IUUC-Olu-087639 Ostreococcus lucimarinus 56.21 0.00e+00 1368.00
IUUC-Oga-087991 Otolemur garnettii 93.97 0.00e+00 2361.00
IUUC-Oar-089590 Ovis aries 99.02 0.00e+00 2501.00
IUUC-Ptr-090808 Pan troglodytes 98.78 0.00e+00 2512.00
IUUC-Pan-092475 Papio anubis 99.10 0.00e+00 2508.00
IUUC-Psi-093044 Pelodiscus sinensis 80.15 0.00e+00 1697.00
IUUC-Pno-094839 Phaeosphaeria nodorum 47.84 0.00e+00 1116.00
IUUC-Ppa-095254 Physcomitrella patens 56.91 0.00e+00 1408.00
IUUC-Pfo-097493 Poecilia formosa 88.07 0.00e+00 2203.00
IUUC-Pab-098497 Pongo abelii 99.59 0.00e+00 2523.00
IUUC-Pop-099992 Populus trichocarpa 56.43 0.00e+00 1345.00
IUUC-Pca-100413 Procavia capensis 89.47 0.00e+00 1011.00
IUUC-Ppe-101899 Prunus persica 54.63 0.00e+00 1328.00
IUUC-Pva-102126 Pteropus vampyrus 94.48 0.00e+00 2375.00
IUUC-Pgr-103376 Puccinia graminis 53.00 0.00e+00 1308.00
IUUC-Ptt-103978 Puccinia triticina 47.39 0.00e+00 1093.00
IUUC-Pte-104126 Pyrenophora teres 56.83 0.00e+00 983.00
IUUC-Pyt-104778 Pyrenophora triticirepentis 46.94 2.00e-179 623.00
IUUC-Rno-105428 Rattus norvegicus 98.69 0.00e+00 2491.00
IUUC-Sce-106464 Saccharomyces cerevisiae 43.62 0.00e+00 1016.00
IUUC-Sha-107301 Sarcophilus harrisii 98.02 0.00e+00 2459.00
IUUC-Sja-107961 Schizosaccharomyces japonicus 45.86 0.00e+00 1098.00
IUUC-Spo-108217 Schizosaccharomyces pombe 47.04 0.00e+00 1140.00
IUUC-Ssl-108643 Sclerotinia sclerotiorum 48.63 0.00e+00 1202.00
IUUC-Smo-109582 Selaginella moellendorffii 65.99 0.00e+00 1160.00
IUUC-Sit-109697 Setaria italica 62.40 0.00e+00 1103.00
IUUC-Sly-111447 Solanum lycopersicum 55.07 0.00e+00 1362.00
IUUC-Stu-112564 Solanum tuberosum 54.94 0.00e+00 1363.00
IUUC-Sar-113313 Sorex araneus 88.38 0.00e+00 1486.00
IUUC-Sbi-114388 Sorghum bicolor 62.99 0.00e+00 1110.00
IUUC-Sre-115209 Sporisorium reilianum 57.71 0.00e+00 1049.00
IUUC-Ssc-115933 Sus scrofa 99.10 0.00e+00 2502.00
IUUC-Tgu-117109 Taeniopygia guttata 81.52 0.00e+00 747.00
IUUC-Tru-117772 Takifugu rubripes 86.92 0.00e+00 2189.00
IUUC-Tsy-119105 Tarsius syrichta 84.43 0.00e+00 2101.00
IUUC-Tni-120556 Tetraodon nigroviridis 70.91 0.00e+00 1527.00
IUUC-Tca-121046 Theobroma cacao 54.60 0.00e+00 1372.00
IUUC-Tre-121951 Trichoderma reesei 57.06 0.00e+00 1020.00
IUUC-Tvi-122359 Trichoderma virens 57.33 0.00e+00 1026.00
IUUC-Tae-125527 Triticum aestivum 53.97 0.00e+00 1328.00
IUUC-Tur-126754 Triticum urartu 62.16 0.00e+00 1103.00
IUUC-Tme-127170 Tuber melanosporum 50.45 0.00e+00 1235.00
IUUC-Tbe-127882 Tupaia belangeri 97.94 0.00e+00 848.00
IUUC-Ttr-128217 Tursiops truncatus 96.19 0.00e+00 2422.00
IUUC-Uma-129337 Ustilago maydis 57.01 0.00e+00 1046.00
IUUC-Vda-129828 Verticillium dahliae 48.43 0.00e+00 1186.00
IUUC-Vpa-130537 Vicugna pacos 97.89 0.00e+00 2451.00
IUUC-Vvi-130958 Vitis vinifera 63.23 0.00e+00 1117.00
IUUC-Xtr-132857 Xenopus tropicalis 90.31 0.00e+00 2278.00
IUUC-Xma-133138 Xiphophorus maculatus 87.83 0.00e+00 2201.00
IUUC-Yli-134399 Yarrowia lipolytica 50.82 0.00e+00 867.00
IUUC-Zma-135612 Zea mays 54.45 0.00e+00 1341.00
Created Date 25-Jun-2017

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