iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bdi-014196

Ensembl Protein ID

BRADI2G10480.1

UniProt Accession

I1HEG8; I1HEG8_BRADI

Protein Name

Presenilin

Gene Name

LOC100838582

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
BRADI2G10480	BRADI2G10480.1	BRADI2G10480.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	31.72	2.00e-35	147.00	IUUC-Cel-018553
UBD/Alpha-Helix/CUE	33.24	9.00e-28	122.00	IUUC-Hsa-046822

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Brachypodium distachyon

Functional Description
(View)

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

Protein Sequence
(Fasta)

MPSLSAPAVV GLELEKRNQT LQPRRGGSDP VEIGKNSPIP LHLRRMDPAA DSPAPAATST 60
ASTILDTLGE EVLAVMSPVS ICMALVVLLI SILSPPSSPA SPSAPPPVTA ATLVYLESPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCAAGTC TCAGCGCACC GGCTGTGGTC GGGCTCGAAC TCGAGAAACG AAACCAAACC 60
CTCCAGCCGC GCCGGGGAGG GAGCGACCCA GTCGAGATCG GGAAAAATTC CCCCATCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP

Pfam

PF01080--Presenilin

PRINTS

PR01072--PRESENILIN

SMART

SM00730--PSN

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0005798--C:Golgi-associated vesicle
GO:0005887--C:integral component of plasma membrane
GO:0005634--C:nucleus
GO:0004190--F:aspartic-type endopeptidase activity
GO:0004175--F:endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000686	Aegilops tauschii	84.44	2.00e-143	502.00
IUUC-Aml-001648	Ailuropoda melanoleuca	33.08	1.00e-34	139.00
IUUC-Atr-003039	Amborella trichopoda	52.71	2.00e-106	378.00
IUUC-Apl-003959	Anas platyrhynchos	30.80	2.00e-26	112.00
IUUC-Aca-004582	Anolis carolinensis	32.37	4.00e-33	134.00
IUUC-Aly-005455	Arabidopsis lyrata	60.43	1.00e-58	219.00
IUUC-Ath-006730	Arabidopsis thaliana	50.87	8.00e-102	363.00
IUUC-Ani-009376	Aspergillus nidulans	45.00	5.80e-01	24.60
IUUC-Ame-011500	Astyanax mexicanus	30.63	1.00e-19	90.50
IUUC-Bta-013026	Bos taurus	30.41	3.00e-31	129.00
IUUC-Bol-015841	Brassica oleracea	53.16	4.00e-96	344.00
IUUC-Bra-017580	Brassica rapa	60.47	9.00e-45	173.00
IUUC-Cel-018553	Caenorhabditis elegans	46.43	9.00e-25	107.00
IUUC-Cja-019994	Callithrix jacchus	30.86	3.00e-29	122.00
IUUC-Cfa-020074	Canis familiaris	31.58	3.00e-34	139.00
IUUC-Cpo-022237	Cavia porcellus	30.63	3.00e-30	125.00
IUUC-Cre-022747	Chlamydomonas reinhardtii	45.22	1.00e-43	170.00
IUUC-Csa-023537	Chlorocebus sabaeus	31.08	4.00e-30	125.00
IUUC-Cho-024735	Choloepus hoffmanni	32.42	1.00e-27	116.00
IUUC-Cin-025780	Ciona intestinalis	32.81	2.00e-40	159.00
IUUC-Csv-025967	Ciona savignyi	31.78	1.00e-23	103.00
IUUC-Dre-028526	Danio rerio	29.74	2.00e-27	116.00
IUUC-Dno-029758	Dasypus novemcinctus	32.21	6.00e-35	140.00
IUUC-Dor-030609	Dipodomys ordii	49.00	3.00e-19	88.60
IUUC-Dme-031929	Drosophila melanogaster	36.32	3.00e-28	119.00
IUUC-Ete-032487	Echinops telfairi	54.00	5.00e-13	68.20
IUUC-Eca-033391	Equus caballus	26.85	3.00e-20	92.00
IUUC-Eeu-035134	Erinaceus europaeus	33.13	3.00e-30	124.00
IUUC-Fca-036243	Felis catus	31.58	7.00e-34	137.00
IUUC-Fal-036600	Ficedula albicollis	30.72	4.00e-33	135.00
IUUC-Gmo-038550	Gadus morhua	33.33	3.00e-28	118.00
IUUC-Gga-040993	Gallus gallus	30.86	3.00e-30	125.00
IUUC-Gac-042511	Gasterosteus aculeatus	32.13	6.00e-38	150.00
IUUC-Gma-043822	Glycine max	59.83	4.00e-44	171.00
IUUC-Ggo-045338	Gorilla gorilla	34.13	9.00e-29	120.00
IUUC-Hsa-046822	Homo sapiens	31.08	4.00e-30	125.00
IUUC-Hvu-047141	Hordeum vulgare	84.35	2.00e-150	524.00
IUUC-Itr-048420	Ictidomys tridecemlineatus	33.97	3.00e-34	138.00
IUUC-Lch-049946	Latimeria chalumnae	31.84	9.00e-22	97.40
IUUC-Lpe-051132	Leersia perrieri	81.33	7.00e-145	506.00
IUUC-Loc-052427	Lepisosteus oculatus	31.03	8.00e-34	137.00
IUUC-Laf-053979	Loxodonta africana	31.99	2.00e-29	122.00
IUUC-Mcc-055682	Macaca mulatta	31.08	4.00e-30	125.00
IUUC-Meu-056004	Macropus eugenii	31.22	4.00e-21	94.70
IUUC-Mtr-058392	Medicago truncatula	51.06	2.00e-99	355.00
IUUC-Mga-059466	Meleagris gallopavo	31.98	2.00e-33	136.00
IUUC-Mmr-060890	Microcebus murinus	32.33	5.00e-28	117.00
IUUC-Mdo-062122	Monodelphis domestica	31.47	5.00e-32	131.00
IUUC-Mmu-063176	Mus musculus	33.03	4.00e-22	98.60
IUUC-Mac-064858	Musa acuminata	83.96	4.00e-45	174.00
IUUC-Mpu-065927	Mustela putorius furo	31.58	3.00e-34	138.00
IUUC-Mlu-067079	Myotis lucifugus	32.46	1.00e-37	150.00
IUUC-Nle-070180	Nomascus leucogenys	31.08	4.00e-30	125.00
IUUC-Opr-070344	Ochotona princeps	33.33	4.00e-26	111.00
IUUC-Ont-071846	Oreochromis niloticus	30.99	1.00e-32	133.00
IUUC-Oan-072783	Ornithorhynchus anatinus	33.33	9.00e-30	123.00
IUUC-Ocu-074527	Oryctolagus cuniculus	33.48	4.00e-22	98.60
IUUC-Oba-075256	Oryza barthii	79.21	8.00e-124	436.00
IUUC-Obr-076302	Oryza brachyantha	80.10	4.00e-138	483.00
IUUC-Ogl-077097	Oryza glaberrima	78.38	6.00e-140	489.00
IUUC-Ogu-078570	Oryza glumaepatula	81.39	6.00e-136	476.00
IUUC-Oin-079244	Oryza indica	78.17	2.00e-139	488.00
IUUC-Olo-080484	Oryza longistaminata	77.82	4.00e-93	333.00
IUUC-Ome-081814	Oryza meridionalis	80.22	2.00e-143	501.00
IUUC-Oni-082057	Oryza nivara	80.89	7.00e-135	473.00
IUUC-Opu-084176	Oryza punctata	81.14	3.00e-137	480.00
IUUC-Oru-084618	Oryza rufipogon	80.89	3.00e-135	474.00
IUUC-Osa-085602	Oryza sativa	81.03	1.00e-136	478.00
IUUC-Ola-086707	Oryzias latipes	32.13	3.00e-27	114.00
IUUC-Olu-087811	Ostreococcus lucimarinus	42.33	3.00e-39	154.00
IUUC-Oga-088560	Otolemur garnettii	33.73	7.00e-29	120.00
IUUC-Oar-090348	Ovis aries	31.00	4.00e-35	141.00
IUUC-Ptr-091060	Pan troglodytes	31.08	4.00e-30	125.00
IUUC-Pan-091742	Papio anubis	33.08	7.00e-29	120.00
IUUC-Psi-093505	Pelodiscus sinensis	29.82	4.00e-29	121.00
IUUC-Pma-094612	Petromyzon marinus	32.05	2.00e-23	102.00
IUUC-Ppa-095431	Physcomitrella patens	49.22	4.00e-53	201.00
IUUC-Pfo-097396	Poecilia formosa	31.13	8.00e-38	150.00
IUUC-Pab-098591	Pongo abelii	31.08	4.00e-30	125.00
IUUC-Pop-099661	Populus trichocarpa	54.82	5.00e-49	187.00
IUUC-Pca-101029	Procavia capensis	31.82	5.00e-27	114.00
IUUC-Ppe-101495	Prunus persica	65.80	2.00e-66	245.00
IUUC-Pva-102244	Pteropus vampyrus	33.33	1.00e-21	97.10
IUUC-Rno-105861	Rattus norvegicus	33.48	4.00e-22	98.60
IUUC-Sha-107045	Sarcophilus harrisii	31.44	3.00e-33	135.00
IUUC-Smo-109325	Selaginella moellendorffii	48.25	6.00e-38	150.00
IUUC-Sit-110624	Setaria italica	80.69	4.00e-139	487.00
IUUC-Sly-110865	Solanum lycopersicum	88.57	3.00e-33	132.00
IUUC-Stu-112433	Solanum tuberosum	91.25	2.00e-39	155.00
IUUC-Sar-113169	Sorex araneus	42.99	2.00e-20	92.80
IUUC-Sbi-114305	Sorghum bicolor	79.78	1.00e-142	498.00
IUUC-Ssc-115766	Sus scrofa	31.00	5.00e-33	134.00
IUUC-Tgu-116469	Taeniopygia guttata	31.40	4.00e-27	114.00
IUUC-Tru-117732	Takifugu rubripes	30.02	1.00e-32	133.00
IUUC-Tsy-119624	Tarsius syrichta	32.13	7.00e-22	97.40
IUUC-Tni-119852	Tetraodon nigroviridis	29.46	1.00e-29	123.00
IUUC-Tca-121865	Theobroma cacao	67.91	2.00e-59	222.00
IUUC-Tae-125925	Triticum aestivum	85.19	1.00e-151	528.00
IUUC-Tur-126237	Triticum urartu	83.65	2.00e-134	471.00
IUUC-Tbe-127632	Tupaia belangeri	33.08	7.00e-29	120.00
IUUC-Ttr-128793	Tursiops truncatus	32.98	3.00e-31	128.00
IUUC-Vpa-130625	Vicugna pacos	41.90	1.00e-19	90.10
IUUC-Vvi-131312	Vitis vinifera	60.87	1.00e-57	216.00
IUUC-Xtr-131790	Xenopus tropicalis	33.18	3.00e-24	105.00
IUUC-Xma-133377	Xiphophorus maculatus	30.49	5.00e-34	138.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence