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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063216
UUCD1 version UUC-MuM-00529
Ensembl Protein ID ENSMUSP00000101616.3
UniProt Accession Q6PE01; Q3TEJ3; Q9DCX3; SNR40_MOUSE
Genbank Protein ID BAB22049.1; BAE41255.1; AAH58365.1
Protein Name U5 small nuclear ribonucleoprotein 40 kDa protein; WD repeat-containing protein 57
Genbank Nucleotide ID AK002371; AK169605; BC058365
Gene Name Snrnp40; Wdr57
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000074088.6 ENSMUST00000105994.3 ENSMUSP00000101616.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
miRTarBasemicroRNATRANSFACRepTar
RAID2
Protein-protein Interaction
IIDHINTMentha
Post-translational Modifications (PTMs)
CPLMPhosphositePlusUniProtmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.70e-46 154.2 150 184
UBD/Beta-Prp 2.10e-79 267.9 63 266
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrt 32
           gHt+ v+++     +  l+++GsdDgt+k+WD+r+
   Q: 150  GHTSFVNSCYParRGpQLVCTGSDDGTVKLWDIRK 184
           8*******9659955588999***********886 PP
   

   UBD/Beta-Prp
   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsg 135
           lsghe+ev+++kf+p+g++l++++ Dr+i +w++  +++   tlkgh+  v+ l+++ +g+ l s+s d+t+ vwd etg+ ++  l+g
   Q: 63   LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYgDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVK-RLKG 150
           8*******************************8765999*********************************************.**** PP
   S: 136  hdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtd 223
           h+++vn+      g +l+ +Gs+D+tv+lWd++ +  ++t++  +t +v  ++f++++ +++sg+ d+++k+wdl++++  +t++gh d
   Q: 151  HTSFVNSCYPARRGpQLVCTGSDDGTVKLWDIRKKAAVQTFQ--NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD 237
           *****************************************7..6******************************************** PP
   S: 224  nvksvrfspnderlvsgssDgsiriWdlr 252
            v+ + +s+++ +l+s ++D+++r+Wd+r
   Q: 238  SVTGLSLSSEGSYLLSNAMDNTVRVWDVR 266
           ***************************97 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Component of the U5 small nuclear ribonucleoprotein (snRNP) complex. The U5 snRNP is part of the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs (By similarity).
 Component of the U5 small nuclear ribonucleoprotein (snRNP) complex. The U5 snRNP is part of the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs (By similarity).
Protein Sequence
(Fasta)
MIEQQKRKGP ELPLVPVKRP RHELLLGAAG AGPGAGPQQA TPGALLQAGP PRCSSLQAPI 60
MLLSGHEGEV YCCKFHPNGS TLASAGFDRL ILLWNVYGDC DNYATLKGHS GAVMELHYNT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063216|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGTTGGAACC AATTGCGCGG CGCCTCCGGT CGGCGGCGCG GTTAGTGGCG GCGCCGAGGA 60
GAGTGGCTGC CGCCATGATC GAGCAGCAGA AGCGTAAGGG CCCGGAGCTA CCCCTGGTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063216|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0488--Methylation
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0747--Spliceosome
KW-0832--Ubl conjugation
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0071011--C:precatalytic spliceosome
GO:0005682--C:U5 snRNP
GO:0003723--F:RNA binding
GO:0006397--P:mRNA processing
GO:0008380--P:RNA splicing
KEGG mmu:66585
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000138 Aegilops tauschii 58.06 6.00e-119 420.00
IUUC-Aml-001428 Ailuropoda melanoleuca 95.61 5.00e-179 619.00
IUUC-Atr-003164 Amborella trichopoda 58.99 2.00e-121 429.00
IUUC-Apl-003447 Anas platyrhynchos 97.21 6.00e-162 563.00
IUUC-Aca-004270 Anolis carolinensis 82.04 8.00e-170 589.00
IUUC-Aly-005659 Arabidopsis lyrata 61.81 2.00e-123 435.00
IUUC-Ath-006764 Arabidopsis thaliana 61.49 3.00e-123 434.00
IUUC-Acl-008324 Aspergillus clavatus 49.05 5.00e-94 337.00
IUUC-Afl-008607 Aspergillus flavus 49.33 3.00e-89 321.00
IUUC-Afu-008998 Aspergillus fumigatus 48.73 1.00e-93 336.00
IUUC-Ani-009363 Aspergillus nidulans 48.42 5.00e-95 340.00
IUUC-Ang-009513 Aspergillus niger 47.85 1.00e-84 306.00
IUUC-Aor-010237 Aspergillus oryzae 50.00 4.00e-95 341.00
IUUC-Ate-010374 Aspergillus terreus 45.89 7.00e-83 300.00
IUUC-Ame-010728 Astyanax mexicanus 83.06 1.00e-171 595.00
IUUC-Bgr-012297 Blumeria graminis 46.52 3.00e-70 258.00
IUUC-Bta-012433 Bos taurus 98.32 0.00e+00 650.00
IUUC-Bci-013763 Botrytis cinerea 50.47 4.00e-95 341.00
IUUC-Bdi-014490 Brachypodium distachyon 58.28 5.00e-119 420.00
IUUC-Bol-016479 Brassica oleracea 61.22 1.00e-123 436.00
IUUC-Bra-017219 Brassica rapa 61.49 1.00e-123 436.00
IUUC-Cel-018512 Caenorhabditis elegans 57.23 6.00e-113 400.00
IUUC-Cja-019308 Callithrix jacchus 97.77 0.00e+00 652.00
IUUC-Cfa-020998 Canis familiaris 98.04 0.00e+00 656.00
IUUC-Cpo-021580 Cavia porcellus 96.93 0.00e+00 650.00
IUUC-Cre-022859 Chlamydomonas reinhardtii 55.10 1.00e-107 382.00
IUUC-Csa-023456 Chlorocebus sabaeus 95.25 0.00e+00 651.00
IUUC-Cho-024644 Choloepus hoffmanni 99.03 7.00e-179 619.00
IUUC-Cin-025463 Ciona intestinalis 58.84 4.00e-127 447.00
IUUC-Cgl-026497 Colletotrichum gloeosporioides 48.42 3.00e-94 338.00
IUUC-Cne-026780 Cryptococcus neoformans 42.72 2.00e-67 249.00
IUUC-Dre-027671 Danio rerio 81.67 3.00e-177 613.00
IUUC-Dno-029769 Dasypus novemcinctus 98.32 0.00e+00 664.00
IUUC-Dor-030776 Dipodomys ordii 98.31 1.00e-86 313.00
IUUC-Dse-031316 Dothistroma septosporum 44.59 6.00e-85 307.00
IUUC-Dme-031756 Drosophila melanogaster 57.73 7.00e-125 440.00
IUUC-Ete-032753 Echinops telfairi 88.55 2.00e-163 568.00
IUUC-Eca-033979 Equus caballus 98.04 0.00e+00 650.00
IUUC-Eeu-034862 Erinaceus europaeus 99.28 5.00e-72 264.00
IUUC-Fca-036110 Felis catus 98.05 9.00e-159 552.00
IUUC-Fal-037648 Ficedula albicollis 97.10 2.00e-176 611.00
IUUC-Fox-037861 Fusarium oxysporum 46.60 1.00e-91 329.00
IUUC-Fso-038405 Fusarium solani 46.60 3.00e-91 328.00
IUUC-Gmo-039383 Gadus morhua 82.78 1.00e-172 598.00
IUUC-Ggr-040082 Gaeumannomyces graminis 45.74 1.00e-83 303.00
IUUC-Gga-040785 Gallus gallus 90.86 1.00e-180 625.00
IUUC-Gac-041645 Gasterosteus aculeatus 82.78 4.00e-170 590.00
IUUC-Gma-044329 Glycine max 59.81 7.00e-122 430.00
IUUC-Ggo-044800 Gorilla gorilla 85.71 6.00e-157 546.00
IUUC-Hsa-045918 Homo sapiens 95.25 0.00e+00 651.00
IUUC-Hvu-047342 Hordeum vulgare 58.06 2.00e-118 419.00
IUUC-Itr-048047 Ictidomys tridecemlineatus 97.72 1.00e-111 395.00
IUUC-Kpa-049149 Komagataella pastoris 34.30 2.00e-36 146.00
IUUC-Lch-050395 Latimeria chalumnae 87.19 0.00e+00 652.00
IUUC-Lpe-051275 Leersia perrieri 58.60 1.00e-119 423.00
IUUC-Loc-052666 Lepisosteus oculatus 85.64 4.00e-173 600.00
IUUC-Lma-053129 Leptosphaeria maculans 45.57 7.00e-88 317.00
IUUC-Laf-054512 Loxodonta africana 94.97 0.00e+00 644.00
IUUC-Mcc-055819 Macaca mulatta 95.25 0.00e+00 651.00
IUUC-Meu-056350 Macropus eugenii 83.66 8.00e-160 556.00
IUUC-Mor-057063 Magnaporthe oryzae 48.42 1.00e-91 329.00
IUUC-Mpo-057369 Magnaporthe poae 46.69 2.00e-84 305.00
IUUC-Mtr-058228 Medicago truncatula 58.86 3.00e-121 428.00
IUUC-Mla-059093 Melampsora laricipopulina 42.38 4.00e-69 254.00
IUUC-Mga-059719 Meleagris gallopavo 96.82 5.00e-178 616.00
IUUC-Mvi-060285 Microbotryum violaceum 39.52 5.00e-63 234.00
IUUC-Mmr-061685 Microcebus murinus 92.46 4.00e-170 590.00
IUUC-Mdo-062121 Monodelphis domestica 92.52 0.00e+00 638.00
IUUC-Mac-065463 Musa acuminata 55.81 3.00e-109 387.00
IUUC-Mpu-066390 Mustela putorius furo 97.77 0.00e+00 664.00
IUUC-Mlu-066932 Myotis lucifugus 97.37 9.00e-180 622.00
IUUC-Nfi-068509 Neosartorya fischeri 49.05 7.00e-94 337.00
IUUC-Ncr-068870 Neurospora crassa 47.65 1.00e-92 333.00
IUUC-Nle-069539 Nomascus leucogenys 95.25 0.00e+00 650.00
IUUC-Opr-070555 Ochotona princeps 86.03 8.00e-167 579.00
IUUC-Ont-071490 Oreochromis niloticus 81.72 1.00e-169 588.00
IUUC-Oan-073044 Ornithorhynchus anatinus 79.61 1.00e-154 539.00
IUUC-Ocu-073764 Oryctolagus cuniculus 98.32 0.00e+00 666.00
IUUC-Oba-075704 Oryza barthii 58.60 1.00e-119 422.00
IUUC-Obr-076455 Oryza brachyantha 58.92 2.00e-119 422.00
IUUC-Ogl-077382 Oryza glaberrima 58.92 9.00e-120 423.00
IUUC-Ogu-078739 Oryza glumaepatula 58.60 1.00e-119 422.00
IUUC-Oin-079072 Oryza indica 58.60 1.00e-119 422.00
IUUC-Olo-080809 Oryza longistaminata 58.60 1.00e-119 422.00
IUUC-Ome-081677 Oryza meridionalis 58.60 3.00e-119 421.00
IUUC-Oni-082937 Oryza nivara 58.60 1.00e-119 422.00
IUUC-Opu-083510 Oryza punctata 58.60 1.00e-119 422.00
IUUC-Oru-084360 Oryza rufipogon 58.60 1.00e-119 423.00
IUUC-Osa-085640 Oryza sativa 58.60 1.00e-119 422.00
IUUC-Ola-086504 Oryzias latipes 81.94 1.00e-170 592.00
IUUC-Olu-087869 Ostreococcus lucimarinus 41.64 4.00e-63 234.00
IUUC-Oga-088773 Otolemur garnettii 98.32 0.00e+00 654.00
IUUC-Oar-089677 Ovis aries 97.51 0.00e+00 644.00
IUUC-Ptr-090724 Pan troglodytes 95.04 4.00e-179 620.00
IUUC-Pan-092683 Papio anubis 95.25 0.00e+00 651.00
IUUC-Psi-093415 Pelodiscus sinensis 98.05 7.00e-176 609.00
IUUC-Pma-094562 Petromyzon marinus 74.86 6.00e-166 576.00
IUUC-Pno-095014 Phaeosphaeria nodorum 48.50 4.00e-88 318.00
IUUC-Ppa-095728 Physcomitrella patens 61.81 2.00e-120 425.00
IUUC-Pfo-096579 Poecilia formosa 82.22 6.00e-169 586.00
IUUC-Pab-098313 Pongo abelii 95.25 0.00e+00 651.00
IUUC-Pop-099747 Populus trichocarpa 60.84 7.00e-123 433.00
IUUC-Pca-100871 Procavia capensis 85.00 1.00e-129 455.00
IUUC-Ppe-101389 Prunus persica 61.49 1.00e-123 436.00
IUUC-Pva-102468 Pteropus vampyrus 84.08 3.00e-149 521.00
IUUC-Pgr-103523 Puccinia graminis 41.46 2.00e-72 266.00
IUUC-Ptt-103930 Puccinia triticina 41.38 3.00e-72 265.00
IUUC-Pte-104299 Pyrenophora teres 48.73 9.00e-94 337.00
IUUC-Pyt-104564 Pyrenophora triticirepentis 49.37 6.00e-94 337.00
IUUC-Rno-105796 Rattus norvegicus 98.32 0.00e+00 659.00
IUUC-Sha-107191 Sarcophilus harrisii 92.24 0.00e+00 638.00
IUUC-Sja-107952 Schizosaccharomyces japonicus 38.26 9.00e-64 236.00
IUUC-Spo-108249 Schizosaccharomyces pombe 43.53 2.00e-80 292.00
IUUC-Ssl-108448 Sclerotinia sclerotiorum 49.84 2.00e-94 338.00
IUUC-Sit-110805 Setaria italica 57.64 8.00e-119 420.00
IUUC-Sly-111567 Solanum lycopersicum 61.08 6.00e-125 440.00
IUUC-Stu-112562 Solanum tuberosum 61.08 1.00e-125 442.00
IUUC-Sar-112991 Sorex araneus 97.72 6.00e-120 422.00
IUUC-Sbi-114010 Sorghum bicolor 57.74 3.00e-118 418.00
IUUC-Sre-114947 Sporisorium reilianum 42.68 1.00e-73 270.00
IUUC-Ssc-115371 Sus scrofa 98.32 0.00e+00 650.00
IUUC-Tgu-117429 Taeniopygia guttata 94.46 3.00e-174 604.00
IUUC-Tru-118081 Takifugu rubripes 83.06 2.00e-172 598.00
IUUC-Tsy-119101 Tarsius syrichta 86.59 2.00e-158 551.00
IUUC-Tni-120532 Tetraodon nigroviridis 82.78 4.00e-170 590.00
IUUC-Tca-121373 Theobroma cacao 61.49 3.00e-124 438.00
IUUC-Tre-122050 Trichoderma reesei 45.95 2.00e-90 325.00
IUUC-Tvi-122394 Trichoderma virens 45.15 1.00e-84 306.00
IUUC-Tae-124661 Triticum aestivum 58.20 3.00e-118 418.00
IUUC-Tme-126998 Tuber melanosporum 51.13 1.00e-93 336.00
IUUC-Tbe-128032 Tupaia belangeri 98.04 0.00e+00 655.00
IUUC-Ttr-129102 Tursiops truncatus 88.55 8.00e-161 559.00
IUUC-Uma-129363 Ustilago maydis 43.30 4.00e-77 281.00
IUUC-Vda-129891 Verticillium dahliae 49.21 2.00e-93 335.00
IUUC-Vpa-130827 Vicugna pacos 97.49 0.00e+00 647.00
IUUC-Vvi-131202 Vitis vinifera 56.13 2.00e-123 435.00
IUUC-Xtr-132769 Xenopus tropicalis 83.15 7.00e-170 589.00
IUUC-Xma-133147 Xiphophorus maculatus 82.22 1.00e-168 585.00
IUUC-Yli-134352 Yarrowia lipolytica 34.11 3.00e-36 145.00
IUUC-Zma-135294 Zea mays 57.74 5.00e-118 417.00
Created Date 25-Jun-2017

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