iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089857

Ensembl Protein ID

ENSOARP00000002847.1

UniProt Accession

W5NXF0; W5NXF0_SHEEP

Genbank Protein ID

ENSOARP00000002847

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01090515

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000002683.1	ENSOART00000002903.1	ENSOARP00000002847.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	93.07	0.00e+00	659.00	IUUC-Hsa-046390
ULD/UDP/UFD/PB1	93.07	0.00e+00	659.00	IUUC-Hsa-046390
UBD/Alpha-Helix/UBA	88.33	0.00e+00	649.00	IUUC-Mmu-063589
UBD/Alpha-Helix/UBA	88.59	0.00e+00	645.00	IUUC-Rno-105539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MCPRPGLESL PSRQWSELVV CPQPCFSLGQ TGGLWFIALQ WPFSTSLSPF QQLCPTETRW 60
VLTCCLLNNL DEDGDLVAFS SDEELTMAMS YVKDDIFRIY IKEKKECRRD QRPPCAQEVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTCCAC GGCCCGGGCT GGAGTCCTTA CCTTCCAGGC AGTGGAGTGA GCTGGTGGTT 60
TGCCCTCAGC CCTGCTTTTC TCTGGGTCAG ACAGGTGGGC TTTGGTTTAT AGCCTTGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00564--PB1
PF16577--UBA_5
PF00569--ZZ

SMART

SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	89.07	5.00e-173	600.00
IUUC-Apl-003897	Anas platyrhynchos	59.84	6.00e-114	404.00
IUUC-Aca-004699	Anolis carolinensis	49.87	2.00e-86	312.00
IUUC-Ame-010982	Astyanax mexicanus	44.78	3.00e-65	242.00
IUUC-Bta-012634	Bos taurus	96.80	0.00e+00	694.00
IUUC-Cel-018540	Caenorhabditis elegans	41.54	6.00e-11	62.80
IUUC-Cja-019684	Callithrix jacchus	90.67	0.00e+00	626.00
IUUC-Cfa-020573	Canis familiaris	84.21	4.00e-140	491.00
IUUC-Cpo-021425	Cavia porcellus	79.73	5.00e-157	547.00
IUUC-Csa-023968	Chlorocebus sabaeus	91.20	3.00e-180	624.00
IUUC-Cho-024596	Choloepus hoffmanni	83.23	5.00e-52	197.00
IUUC-Cin-025557	Ciona intestinalis	25.95	1.00e-17	84.00
IUUC-Csv-025974	Ciona savignyi	54.17	7.00e-09	54.70
IUUC-Cne-027045	Cryptococcus neoformans	54.35	5.00e-09	57.00
IUUC-Dre-028621	Danio rerio	45.52	3.00e-84	305.00
IUUC-Dno-029060	Dasypus novemcinctus	86.88	0.00e+00	654.00
IUUC-Dor-030547	Dipodomys ordii	88.78	4.00e-108	384.00
IUUC-Ete-033201	Echinops telfairi	78.99	6.00e-162	563.00
IUUC-Eca-033456	Equus caballus	90.55	0.00e+00	676.00
IUUC-Eeu-035157	Erinaceus europaeus	84.88	4.00e-173	600.00
IUUC-Fca-035403	Felis catus	89.33	9.00e-178	616.00
IUUC-Fal-036798	Ficedula albicollis	58.75	5.00e-119	421.00
IUUC-Gmo-039619	Gadus morhua	44.08	4.00e-43	168.00
IUUC-Gga-040137	Gallus gallus	57.67	6.00e-117	414.00
IUUC-Gac-042410	Gasterosteus aculeatus	48.16	9.00e-88	317.00
IUUC-Ggo-044690	Gorilla gorilla	92.80	0.00e+00	627.00
IUUC-Hsa-046390	Homo sapiens	93.07	0.00e+00	627.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	89.87	0.00e+00	665.00
IUUC-Lch-049658	Latimeria chalumnae	49.11	5.00e-101	361.00
IUUC-Loc-052589	Lepisosteus oculatus	49.75	1.00e-96	347.00
IUUC-Laf-053746	Loxodonta africana	79.37	1.00e-160	559.00
IUUC-Mcc-055635	Macaca mulatta	91.47	0.00e+00	630.00
IUUC-Meu-056528	Macropus eugenii	49.60	1.00e-92	332.00
IUUC-Mga-059458	Meleagris gallopavo	58.50	8.00e-117	413.00
IUUC-Mvi-060347	Microbotryum violaceum	54.05	1.00e-07	52.40
IUUC-Mmr-061539	Microcebus murinus	82.14	9.00e-109	386.00
IUUC-Mdo-063083	Monodelphis domestica	64.51	9.00e-132	463.00
IUUC-Mmu-063589	Mus musculus	87.53	0.00e+00	641.00
IUUC-Mpu-065727	Mustela putorius furo	88.44	0.00e+00	628.00
IUUC-Mlu-067026	Myotis lucifugus	88.00	0.00e+00	648.00
IUUC-Nle-069356	Nomascus leucogenys	59.42	1.00e-91	329.00
IUUC-Opr-071091	Ochotona princeps	68.18	1.00e-82	300.00
IUUC-Ont-071864	Oreochromis niloticus	48.70	1.00e-92	333.00
IUUC-Oan-073308	Ornithorhynchus anatinus	65.47	5.00e-126	444.00
IUUC-Ocu-074110	Oryctolagus cuniculus	91.47	0.00e+00	650.00
IUUC-Ola-086944	Oryzias latipes	45.05	5.00e-39	153.00
IUUC-Oga-088869	Otolemur garnettii	90.48	0.00e+00	653.00
IUUC-Ptr-091640	Pan troglodytes	93.07	0.00e+00	627.00
IUUC-Pan-092831	Papio anubis	92.59	0.00e+00	645.00
IUUC-Psi-093925	Pelodiscus sinensis	57.18	1.00e-113	403.00
IUUC-Pma-094576	Petromyzon marinus	32.22	3.00e-23	102.00
IUUC-Pfo-097297	Poecilia formosa	46.65	2.00e-82	299.00
IUUC-Pab-098725	Pongo abelii	80.53	7.00e-154	536.00
IUUC-Pca-101106	Procavia capensis	90.13	2.00e-176	611.00
IUUC-Pva-102710	Pteropus vampyrus	86.07	7.00e-155	540.00
IUUC-Rno-105539	Rattus norvegicus	88.59	0.00e+00	654.00
IUUC-Sha-107469	Sarcophilus harrisii	58.67	5.00e-124	437.00
IUUC-Ssc-115526	Sus scrofa	93.07	0.00e+00	647.00
IUUC-Tgu-117194	Taeniopygia guttata	59.90	2.00e-117	415.00
IUUC-Tru-117896	Takifugu rubripes	47.96	2.00e-88	318.00
IUUC-Tni-119943	Tetraodon nigroviridis	49.61	3.00e-79	288.00
IUUC-Ttr-128676	Tursiops truncatus	93.33	0.00e+00	687.00
IUUC-Vda-129812	Verticillium dahliae	37.33	2.00e-07	50.80
IUUC-Vpa-130319	Vicugna pacos	96.00	1.00e-56	213.00
IUUC-Xtr-132907	Xenopus tropicalis	56.74	4.00e-114	404.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence