iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020737

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03003643

Gene Name

RNF222

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000017068.3	ENSCAFT00000027031.3	ENSCAFP00000025131.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.00e-09	39.1	30	81

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf....kdgplvlpCgHvfhadClqkw.....pglknssskefrCPlCr 46
           C++C+e f        ++l+CgHvf++dCl k+     ++ +   ++++ CP+Cr
   Q: 30   CPVCYEKFrdleG-ASRTLSCGHVFCHDCLVKYllstrVDGQ--VQRTIVCPICR 81
           ********55532.3899************999888665555..889999****8 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

PGPSLPQLRP CLGRVAMSEG ESKDSSGSEC PVCYEKFRDL EGASRTLSCG HVFCHDCLVK 60
YLLSTRVDGQ VQRTIVCPIC RYVTFLSKKS SRWPSVLDRS SQTLAVPMGL PDALGHTNPQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGGCCCTT CCCTCCCGCA GCTAAGGCCC TGCCTTGGCA GAGTGGCCAT GTCCGAAGGA 60
GAGAGCAAAG ACAGCTCGGG CAGCGAGTGC CCCGTGTGCT ACGAGAAGTT CCGCGACCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0033768--C:SUMO-targeted ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0033234--P:negative regulation of protein sumoylation
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001331	Ailuropoda melanoleuca	96.43	1.00e-44	171.00
IUUC-Apl-003509	Anas platyrhynchos	46.15	3.00e-36	145.00
IUUC-Aca-004916	Anolis carolinensis	37.68	2.00e-26	112.00
IUUC-Bta-013443	Bos taurus	80.98	1.00e-63	236.00
IUUC-Cja-019637	Callithrix jacchus	79.13	1.00e-62	232.00
IUUC-Cpo-022224	Cavia porcellus	76.07	7.00e-65	239.00
IUUC-Csa-024175	Chlorocebus sabaeus	75.98	1.00e-70	259.00
IUUC-Dre-028060	Danio rerio	35.44	7.00e-22	97.10
IUUC-Dno-030024	Dasypus novemcinctus	76.69	2.00e-58	218.00
IUUC-Dor-030936	Dipodomys ordii	78.24	1.00e-70	259.00
IUUC-Eca-033759	Equus caballus	82.51	2.00e-75	274.00
IUUC-Fal-037142	Ficedula albicollis	44.56	2.00e-29	121.00
IUUC-Gmo-039196	Gadus morhua	38.19	3.00e-21	94.70
IUUC-Gga-041189	Gallus gallus	46.79	8.00e-32	129.00
IUUC-Gac-041497	Gasterosteus aculeatus	41.40	1.00e-23	102.00
IUUC-Ggo-045020	Gorilla gorilla	77.58	3.00e-66	244.00
IUUC-Hsa-046317	Homo sapiens	75.76	4.00e-63	234.00
IUUC-Itr-048656	Ictidomys tridecemlineatus	80.00	6.00e-74	269.00
IUUC-Lch-049885	Latimeria chalumnae	37.50	2.00e-22	98.60
IUUC-Laf-053457	Loxodonta africana	73.20	4.00e-65	240.00
IUUC-Mcc-054653	Macaca mulatta	75.32	5.00e-61	226.00
IUUC-Mga-059753	Meleagris gallopavo	46.11	1.00e-34	139.00
IUUC-Mdo-062993	Monodelphis domestica	69.12	1.00e-67	248.00
IUUC-Mmu-063225	Mus musculus	80.59	3.00e-66	244.00
IUUC-Mpu-066299	Mustela putorius furo	88.02	3.00e-70	257.00
IUUC-Mlu-066988	Myotis lucifugus	76.74	4.00e-65	240.00
IUUC-Nle-069011	Nomascus leucogenys	76.58	7.00e-62	229.00
IUUC-Opr-070258	Ochotona princeps	77.65	1.00e-63	235.00
IUUC-Ont-071886	Oreochromis niloticus	39.63	1.00e-23	102.00
IUUC-Ocu-074282	Oryctolagus cuniculus	82.94	1.00e-67	249.00
IUUC-Oga-088403	Otolemur garnettii	72.68	4.00e-64	237.00
IUUC-Oar-089665	Ovis aries	87.30	5.00e-20	88.60
IUUC-Ptr-090580	Pan troglodytes	76.36	2.00e-63	234.00
IUUC-Pan-092447	Papio anubis	75.95	1.00e-61	229.00
IUUC-Psi-093673	Pelodiscus sinensis	46.22	5.00e-40	157.00
IUUC-Ppa-095340	Physcomitrella patens	32.18	1.00e-07	50.40
IUUC-Pfo-096933	Poecilia formosa	33.15	2.00e-20	92.00
IUUC-Pab-097867	Pongo abelii	75.32	1.00e-59	222.00
IUUC-Pva-102146	Pteropus vampyrus	82.35	2.00e-70	258.00
IUUC-Rno-105897	Rattus norvegicus	82.35	1.00e-67	248.00
IUUC-Sha-107282	Sarcophilus harrisii	68.53	2.00e-56	211.00
IUUC-Sar-113260	Sorex araneus	80.00	3.00e-74	271.00
IUUC-Ssc-115449	Sus scrofa	75.54	2.00e-57	214.00
IUUC-Tgu-117349	Taeniopygia guttata	42.70	1.00e-28	119.00
IUUC-Xtr-132180	Xenopus tropicalis	40.11	1.00e-23	102.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence