iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049098

Ensembl Protein ID

CAY67739

UniProt Accession

C4QWW6; C4QWW6_KOMPG

Genbank Protein ID

CAY67739.1

Protein Name

Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p

Genbank Nucleotide ID

FN392319

Gene Name

PAS_chr1-1_0363

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr1-1_0363	CAY67739	CAY67739

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.00e-81	273.0	1301	1665

Active Site

Position(s)	Description	Evidence
1634	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp..........ehlklFeflGrllgkalqdgrlldlpl 92
           d+ + le+e+ gEeg++l G+t+ef+a++ske+ +++lg++++s+++     +++++gl +           + l lF+ lG++++ +l d+r++d ++
   Q: 1301 DVPSILEIEYFGEEGTGL-GPTLEFYANVSKEFTKNKLGMWRTSDKEAIY--VSSKTGLFPRpialdvneihKPLHLFKVLGIFVARSLLDSRIIDFEF 1396
           778899************.**********************988874443..3444444333477888889999************************* PP
   S: 93   sksfykll..........lgkklsledleevdpelykslkeikenaes..........dieelgldltfsvseeilgetkeeeLkpgGenipVtneNke 171
           +++f+ +           l++++ l+ l e+dp l ksl ++++ +e+          +i+ ++  l+    + +l+ + + eL ++G+++++t eN+e
   Q: 1397 NPFFFHTAknmvlgvqekLNRRVLLDRLDEIDPVLSKSLRYLLKFVEQypnvppdlrdSITVEDSPLSNLSLNYVLPGYPDIELTEDGADTEITHENLE 1495
           *****98866677766666669*********************99965666666555555555555555555666************************ PP
   S: 172  eYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvT 269
           +Y++ v++y+l+ gi++qv +f +Gf++v+p ++l +F+++el  l   + e+++ +++ +    ++gy+ +s a+q++++ ++ef+++e+++fLqF+T
   Q: 1496 DYIDEVLDYTLQYGIEQQVRSFIDGFSTVFPYSSLLIFSASELVKLFGNSsEDWSYDTVMASVHADHGYSIESAAVQNLIQLMSEFTKDEQRMFLQFLT 1594
           *******************************************9988777899999999999999********************************** PP
   S: 270  gssrlPlgGfaelkprlfvirk.....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFe 334
           gs+rlP+gGf+elkp+l+v+rk        d+ lPs++TC+nyLkLP+Y++kei++++++ Ai+e+  +F 
   Q: 1595 GSPRLPIGGFKELKPQLTVVRKttedgLLPDNYLPSVMTCANYLKLPNYTNKEIMRQRIMQAIKEGaGAFL 1665
           **********************9886656789*********************************977775 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MSSDKEKLKH LKASKSPKWL DSKREDSSPN PRRSSDLAIP GSSINHTLPD NTDNSEASRN 60
NGTKVKNSSD FGFISNLRRA FEGTQERQAN GNGSDDIDVV EDQGRTVLQS GSSVNDSSHE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTTCTG ATAAAGAAAA GTTAAAACAT CTAAAGGCCA GTAAATCACC CAAATGGCTT 60
GACTCAAAGA GGGAAGACTC TTCACCCAAC CCCCGAAGGT CTTCCGACCT TGCAATTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ppa:PAS_chr1-1_0363

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000060	Aegilops tauschii	38.53	5.00e-99	354.00
IUUC-Aml-001502	Ailuropoda melanoleuca	38.49	3.00e-98	352.00
IUUC-Atr-002821	Amborella trichopoda	37.74	3.00e-98	352.00
IUUC-Apl-003531	Anas platyrhynchos	36.90	6.00e-89	321.00
IUUC-Aca-004521	Anolis carolinensis	37.97	7.00e-35	142.00
IUUC-Aly-005962	Arabidopsis lyrata	40.31	8.00e-101	360.00
IUUC-Ath-006636	Arabidopsis thaliana	39.30	2.00e-100	359.00
IUUC-Ago-007875	Ashbya gossypii	34.64	2.00e-156	545.00
IUUC-Acl-008242	Aspergillus clavatus	44.09	4.00e-136	477.00
IUUC-Afl-008736	Aspergillus flavus	43.19	2.00e-136	479.00
IUUC-Afu-008812	Aspergillus fumigatus	43.55	7.00e-136	476.00
IUUC-Ani-009407	Aspergillus nidulans	44.21	5.00e-135	474.00
IUUC-Ang-009763	Aspergillus niger	43.34	2.00e-126	446.00
IUUC-Aor-009941	Aspergillus oryzae	40.42	8.00e-154	536.00
IUUC-Ate-010459	Aspergillus terreus	43.09	4.00e-114	404.00
IUUC-Ame-011761	Astyanax mexicanus	38.10	4.00e-96	345.00
IUUC-Bgr-012265	Blumeria graminis	43.30	2.00e-130	459.00
IUUC-Bta-013070	Bos taurus	38.49	2.00e-98	352.00
IUUC-Bci-013890	Botrytis cinerea	48.17	3.00e-126	445.00
IUUC-Bdi-014961	Brachypodium distachyon	35.54	1.00e-99	356.00
IUUC-Bol-015942	Brassica oleracea	38.21	9.00e-99	353.00
IUUC-Bra-016849	Brassica rapa	38.37	1.00e-98	353.00
IUUC-Cel-018153	Caenorhabditis elegans	31.59	4.00e-77	282.00
IUUC-Cja-019046	Callithrix jacchus	38.49	4.00e-98	351.00
IUUC-Cfa-020521	Canis familiaris	38.29	1.00e-97	350.00
IUUC-Cpo-021639	Cavia porcellus	38.29	1.00e-97	349.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	35.92	2.00e-85	307.00
IUUC-Csa-023231	Chlorocebus sabaeus	38.49	4.00e-98	351.00
IUUC-Cho-024380	Choloepus hoffmanni	38.98	3.00e-80	292.00
IUUC-Cin-025482	Ciona intestinalis	33.89	3.00e-89	320.00
IUUC-Csv-026121	Ciona savignyi	36.82	1.00e-92	333.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	45.22	3.00e-140	491.00
IUUC-Cne-026857	Cryptococcus neoformans	42.55	1.00e-117	416.00
IUUC-Cme-027226	Cyanidioschyzon merolae	33.15	8.00e-75	274.00
IUUC-Dre-028174	Danio rerio	38.10	2.00e-96	345.00
IUUC-Dno-029954	Dasypus novemcinctus	37.20	6.00e-35	142.00
IUUC-Dor-030939	Dipodomys ordii	33.93	6.00e-78	284.00
IUUC-Dse-031444	Dothistroma septosporum	42.53	7.00e-135	473.00
IUUC-Dme-031739	Drosophila melanogaster	31.26	2.00e-72	266.00
IUUC-Ete-032345	Echinops telfairi	32.34	1.00e-68	253.00
IUUC-Eca-033229	Equus caballus	38.49	5.00e-98	351.00
IUUC-Eeu-035205	Erinaceus europaeus	38.31	2.00e-97	349.00
IUUC-Fca-036444	Felis catus	38.49	5.00e-98	351.00
IUUC-Fal-037131	Ficedula albicollis	38.69	3.00e-98	352.00
IUUC-Fox-038035	Fusarium oxysporum	44.94	8.00e-141	491.00
IUUC-Fso-038320	Fusarium solani	44.03	6.00e-137	480.00
IUUC-Gmo-039497	Gadus morhua	37.90	7.00e-96	344.00
IUUC-Ggr-040057	Gaeumannomyces graminis	45.81	6.00e-143	500.00
IUUC-Gga-041021	Gallus gallus	38.69	2.00e-98	352.00
IUUC-Gac-042474	Gasterosteus aculeatus	38.10	2.00e-96	345.00
IUUC-Gma-043060	Glycine max	33.24	7.00e-96	343.00
IUUC-Ggo-044855	Gorilla gorilla	38.49	4.00e-98	351.00
IUUC-Hsa-046147	Homo sapiens	38.49	5.00e-98	351.00
IUUC-Hvu-047775	Hordeum vulgare	38.11	6.00e-97	347.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	38.49	2.00e-97	349.00
IUUC-Lch-049818	Latimeria chalumnae	36.94	4.00e-92	332.00
IUUC-Lpe-051017	Leersia perrieri	37.48	3.00e-94	338.00
IUUC-Loc-051777	Lepisosteus oculatus	37.90	3.00e-96	345.00
IUUC-Lma-052990	Leptosphaeria maculans	43.89	2.00e-133	469.00
IUUC-Laf-053727	Loxodonta africana	38.29	8.00e-98	350.00
IUUC-Mcc-055799	Macaca mulatta	38.49	4.00e-98	351.00
IUUC-Meu-056065	Macropus eugenii	35.31	6.00e-73	268.00
IUUC-Mor-057054	Magnaporthe oryzae	46.07	6.00e-142	497.00
IUUC-Mpo-057417	Magnaporthe poae	45.72	2.00e-141	495.00
IUUC-Mtr-057849	Medicago truncatula	37.44	3.00e-95	342.00
IUUC-Mla-058870	Melampsora laricipopulina	40.36	1.00e-118	419.00
IUUC-Mga-059409	Meleagris gallopavo	37.68	2.00e-35	143.00
IUUC-Mvi-060507	Microbotryum violaceum	40.00	3.00e-123	435.00
IUUC-Mmr-060816	Microcebus murinus	38.29	6.00e-97	347.00
IUUC-Mdo-062866	Monodelphis domestica	35.68	3.00e-74	272.00
IUUC-Mmu-063906	Mus musculus	37.90	1.00e-95	343.00
IUUC-Mac-064675	Musa acuminata	39.05	1.00e-95	342.00
IUUC-Mpu-066199	Mustela putorius furo	38.49	4.00e-98	351.00
IUUC-Mlu-067110	Myotis lucifugus	38.69	1.00e-96	347.00
IUUC-Nfi-068482	Neosartorya fischeri	43.39	1.00e-134	473.00
IUUC-Ncr-068906	Neurospora crassa	45.13	9.00e-140	489.00
IUUC-Nle-069410	Nomascus leucogenys	38.49	4.00e-98	351.00
IUUC-Opr-070401	Ochotona princeps	36.86	2.00e-45	177.00
IUUC-Ont-072100	Oreochromis niloticus	37.45	9.00e-96	343.00
IUUC-Oan-073121	Ornithorhynchus anatinus	38.29	3.00e-97	348.00
IUUC-Ocu-074623	Oryctolagus cuniculus	38.49	5.00e-98	351.00
IUUC-Oba-075380	Oryza barthii	36.60	4.00e-86	311.00
IUUC-Obr-076915	Oryza brachyantha	33.72	7.00e-93	334.00
IUUC-Ogl-077055	Oryza glaberrima	37.62	7.00e-94	337.00
IUUC-Ogu-078892	Oryza glumaepatula	36.80	7.00e-86	310.00
IUUC-Oin-079256	Oryza indica	37.20	9.00e-92	330.00
IUUC-Olo-080343	Oryza longistaminata	37.20	4.00e-91	328.00
IUUC-Ome-081422	Oryza meridionalis	37.20	4.00e-91	328.00
IUUC-Oni-082469	Oryza nivara	36.70	1.00e-86	313.00
IUUC-Opu-083641	Oryza punctata	35.80	9.00e-85	306.00
IUUC-Oru-084439	Oryza rufipogon	36.40	6.00e-86	310.00
IUUC-Osa-085972	Oryza sativa	37.62	4.00e-93	333.00
IUUC-Ola-087173	Oryzias latipes	37.50	2.00e-95	343.00
IUUC-Olu-087871	Ostreococcus lucimarinus	35.28	6.00e-84	302.00
IUUC-Oga-087908	Otolemur garnettii	38.29	2.00e-97	349.00
IUUC-Oar-090277	Ovis aries	38.49	2.00e-98	353.00
IUUC-Ptr-091543	Pan troglodytes	38.49	6.00e-98	351.00
IUUC-Pan-092243	Papio anubis	38.49	4.00e-98	351.00
IUUC-Psi-093150	Pelodiscus sinensis	37.90	5.00e-97	348.00
IUUC-Pno-094891	Phaeosphaeria nodorum	49.19	3.00e-133	468.00
IUUC-Ppa-095181	Physcomitrella patens	39.64	3.00e-96	343.00
IUUC-Pfo-096267	Poecilia formosa	37.30	3.00e-95	342.00
IUUC-Pab-098072	Pongo abelii	38.49	4.00e-98	351.00
IUUC-Pop-099190	Populus trichocarpa	38.67	3.00e-98	352.00
IUUC-Pca-100311	Procavia capensis	38.29	6.00e-98	351.00
IUUC-Ppe-101284	Prunus persica	38.45	3.00e-98	352.00
IUUC-Pva-102215	Pteropus vampyrus	35.71	2.00e-84	306.00
IUUC-Pgr-103694	Puccinia graminis	42.33	4.00e-123	434.00
IUUC-Ptt-103916	Puccinia triticina	40.39	3.00e-115	408.00
IUUC-Pte-104346	Pyrenophora teres	43.27	6.00e-136	477.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	43.34	4.00e-136	478.00
IUUC-Rno-105315	Rattus norvegicus	38.49	2.00e-97	349.00
IUUC-Sce-106273	Saccharomyces cerevisiae	37.93	3.00e-132	464.00
IUUC-Sha-106835	Sarcophilus harrisii	38.29	4.00e-97	348.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	45.04	3.00e-123	434.00
IUUC-Spo-108081	Schizosaccharomyces pombe	37.28	2.00e-129	455.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	43.13	3.00e-132	464.00
IUUC-Smo-109590	Selaginella moellendorffii	39.70	1.00e-100	359.00
IUUC-Sit-110717	Setaria italica	37.57	2.00e-95	342.00
IUUC-Sly-111557	Solanum lycopersicum	37.70	2.00e-99	355.00
IUUC-Stu-112896	Solanum tuberosum	38.18	5.00e-89	320.00
IUUC-Sar-113224	Sorex araneus	39.90	1.00e-75	276.00
IUUC-Sbi-113884	Sorghum bicolor	37.87	6.00e-97	347.00
IUUC-Sre-114993	Sporisorium reilianum	39.31	2.00e-121	429.00
IUUC-Ssc-115535	Sus scrofa	36.82	8.00e-85	307.00
IUUC-Tgu-117167	Taeniopygia guttata	37.97	2.00e-35	142.00
IUUC-Tru-118669	Takifugu rubripes	37.82	2.00e-95	342.00
IUUC-Tsy-119373	Tarsius syrichta	32.04	3.00e-60	225.00
IUUC-Tni-120049	Tetraodon nigroviridis	34.63	8.00e-74	269.00
IUUC-Tca-121779	Theobroma cacao	38.20	4.00e-96	345.00
IUUC-Tre-122195	Trichoderma reesei	43.43	1.00e-138	486.00
IUUC-Tvi-122650	Trichoderma virens	43.83	8.00e-142	496.00
IUUC-Tae-123120	Triticum aestivum	38.35	4.00e-99	355.00
IUUC-Tur-126295	Triticum urartu	38.31	1.00e-97	350.00
IUUC-Tme-126964	Tuber melanosporum	43.61	4.00e-135	474.00
IUUC-Tbe-128149	Tupaia belangeri	35.57	2.00e-58	220.00
IUUC-Ttr-128165	Tursiops truncatus	38.49	2.00e-98	352.00
IUUC-Uma-129365	Ustilago maydis	46.75	7.00e-112	397.00
IUUC-Vda-129725	Verticillium dahliae	45.21	2.00e-145	508.00
IUUC-Vpa-130678	Vicugna pacos	38.49	3.00e-98	352.00
IUUC-Vvi-131539	Vitis vinifera	37.60	1.00e-94	340.00
IUUC-Xtr-132636	Xenopus tropicalis	38.14	7.00e-95	340.00
IUUC-Xma-133458	Xiphophorus maculatus	37.30	3.00e-95	342.00
IUUC-Yli-134481	Yarrowia lipolytica	42.13	9.00e-127	446.00
IUUC-Zma-135657	Zea mays	37.99	2.00e-96	345.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence