iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074063

Ensembl Protein ID

ENSOCUP00000015378.2

UniProt Accession

G1TEP5; G1TEP5_RABIT

Protein Name

Uncharacterized protein

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000017898.3	ENSOCUT00000017898.3	ENSOCUP00000015378.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	87.38	0.00e+00	722.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MERSKENCIS GPIKAAALLG DGPKRVPVTQ RFPSQNPVSA CSGQAERVLC PSNSSQRVPS 60
QAQKLLPAEK PVQKLKQAQA ASVPRPVSKP PNNTPKSEQP PPSAPGNNPE KELTSNQKNE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCATCATGGA AAGATCCAAA GAAAACTGCA TTTCAGGGCC TATTAAGGTA AACAGAAAAG 60
TCTAATTGCG ATCAGCTCAT AGACTCATGG GGCTCAGGCT CCTGGAGTTC TTCCCACCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

KEGG

ocu:100345632

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	64.16	9.00e-105	372.00
IUUC-Aml-001426	Ailuropoda melanoleuca	87.56	0.00e+00	701.00
IUUC-Atr-002453	Amborella trichopoda	64.48	7.00e-108	383.00
IUUC-Apl-003626	Anas platyrhynchos	71.79	1.00e-153	535.00
IUUC-Aca-004602	Anolis carolinensis	67.98	2.00e-152	532.00
IUUC-Aly-005878	Arabidopsis lyrata	64.10	9.00e-105	372.00
IUUC-Ath-007117	Arabidopsis thaliana	64.47	3.00e-105	374.00
IUUC-Acl-008199	Aspergillus clavatus	50.77	2.00e-87	315.00
IUUC-Afl-008419	Aspergillus flavus	56.36	1.00e-85	310.00
IUUC-Afu-008751	Aspergillus fumigatus	59.22	6.00e-86	310.00
IUUC-Ani-009181	Aspergillus nidulans	53.40	2.00e-90	325.00
IUUC-Ang-009787	Aspergillus niger	58.43	1.00e-85	310.00
IUUC-Aor-009980	Aspergillus oryzae	56.36	1.00e-85	310.00
IUUC-Ate-010286	Aspergillus terreus	58.82	9.00e-86	310.00
IUUC-Ame-010849	Astyanax mexicanus	59.55	4.00e-130	457.00
IUUC-Bgr-012110	Blumeria graminis	57.71	9.00e-87	313.00
IUUC-Bta-013474	Bos taurus	87.38	0.00e+00	717.00
IUUC-Bci-013756	Botrytis cinerea	55.85	5.00e-93	334.00
IUUC-Bdi-014257	Brachypodium distachyon	62.20	3.00e-105	374.00
IUUC-Bol-016310	Brassica oleracea	61.89	2.00e-102	365.00
IUUC-Bra-017438	Brassica rapa	61.89	2.00e-103	368.00
IUUC-Cel-018157	Caenorhabditis elegans	59.23	2.00e-100	358.00
IUUC-Cja-019282	Callithrix jacchus	86.82	0.00e+00	696.00
IUUC-Cfa-020162	Canis familiaris	86.27	0.00e+00	696.00
IUUC-Cpo-021764	Cavia porcellus	83.46	0.00e+00	664.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	68.42	5.00e-109	386.00
IUUC-Csa-023694	Chlorocebus sabaeus	86.88	0.00e+00	658.00
IUUC-Cho-024350	Choloepus hoffmanni	93.88	6.00e-110	389.00
IUUC-Cin-025542	Ciona intestinalis	72.35	6.00e-117	413.00
IUUC-Csv-025873	Ciona savignyi	68.29	4.00e-118	417.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	54.85	9.00e-80	290.00
IUUC-Cne-026928	Cryptococcus neoformans	59.18	2.00e-94	339.00
IUUC-Cme-027336	Cyanidioschyzon merolae	71.59	2.00e-117	415.00
IUUC-Dre-028198	Danio rerio	64.08	5.00e-132	464.00
IUUC-Dno-029928	Dasypus novemcinctus	83.42	0.00e+00	633.00
IUUC-Dor-030238	Dipodomys ordii	78.91	0.00e+00	639.00
IUUC-Dse-031266	Dothistroma septosporum	50.87	3.00e-91	328.00
IUUC-Dme-032007	Drosophila melanogaster	61.83	1.00e-101	363.00
IUUC-Ete-032911	Echinops telfairi	67.72	4.00e-133	467.00
IUUC-Eca-033749	Equus caballus	87.56	0.00e+00	695.00
IUUC-Eeu-035170	Erinaceus europaeus	83.46	0.00e+00	693.00
IUUC-Fca-035498	Felis catus	88.11	0.00e+00	695.00
IUUC-Fal-037397	Ficedula albicollis	66.91	4.00e-148	517.00
IUUC-Fox-037747	Fusarium oxysporum	49.70	4.00e-90	324.00
IUUC-Fso-038429	Fusarium solani	51.74	3.00e-89	321.00
IUUC-Gmo-039378	Gadus morhua	60.25	2.00e-128	451.00
IUUC-Ggr-039939	Gaeumannomyces graminis	57.65	1.00e-93	336.00
IUUC-Gga-040187	Gallus gallus	68.58	4.00e-149	520.00
IUUC-Gac-042223	Gasterosteus aculeatus	61.31	3.00e-132	464.00
IUUC-Gma-042870	Glycine max	63.70	3.00e-99	354.00
IUUC-Ggo-045617	Gorilla gorilla	87.13	0.00e+00	720.00
IUUC-Hsa-046968	Homo sapiens	87.38	0.00e+00	722.00
IUUC-Hvu-047072	Hordeum vulgare	53.26	1.00e-79	289.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	74.81	1.00e-172	598.00
IUUC-Kpa-049093	Komagataella pastoris	55.04	3.00e-74	271.00
IUUC-Lch-050346	Latimeria chalumnae	67.87	2.00e-146	511.00
IUUC-Lpe-051466	Leersia perrieri	66.67	1.00e-106	379.00
IUUC-Lma-053006	Leptosphaeria maculans	49.70	5.00e-88	317.00
IUUC-Laf-053422	Loxodonta africana	83.91	0.00e+00	695.00
IUUC-Mcc-055245	Macaca mulatta	86.65	0.00e+00	647.00
IUUC-Mor-056952	Magnaporthe oryzae	55.80	2.00e-89	322.00
IUUC-Mpo-057605	Magnaporthe poae	55.48	4.00e-94	338.00
IUUC-Mtr-057726	Medicago truncatula	63.80	3.00e-105	374.00
IUUC-Mla-059174	Melampsora laricipopulina	58.16	4.00e-97	348.00
IUUC-Mga-059562	Meleagris gallopavo	58.59	1.00e-114	405.00
IUUC-Mvi-060305	Microbotryum violaceum	60.08	4.00e-92	332.00
IUUC-Mmr-061588	Microcebus murinus	84.08	0.00e+00	700.00
IUUC-Mdo-061914	Monodelphis domestica	77.00	3.00e-173	600.00
IUUC-Mmu-063288	Mus musculus	82.13	0.00e+00	650.00
IUUC-Mac-064969	Musa acuminata	66.05	7.00e-106	376.00
IUUC-Mpu-066855	Mustela putorius furo	86.79	0.00e+00	696.00
IUUC-Mlu-068046	Myotis lucifugus	84.72	0.00e+00	671.00
IUUC-Nfi-068527	Neosartorya fischeri	52.38	4.00e-86	311.00
IUUC-Ncr-068678	Neurospora crassa	57.76	2.00e-91	329.00
IUUC-Nle-069848	Nomascus leucogenys	86.39	0.00e+00	713.00
IUUC-Opr-070589	Ochotona princeps	88.12	0.00e+00	678.00
IUUC-Ont-071733	Oreochromis niloticus	61.03	3.00e-126	444.00
IUUC-Oan-073399	Ornithorhynchus anatinus	87.46	2.00e-150	524.00
IUUC-Oba-075264	Oryza barthii	66.30	2.00e-105	375.00
IUUC-Obr-076048	Oryza brachyantha	65.68	2.00e-105	374.00
IUUC-Ogl-077637	Oryza glaberrima	66.30	2.00e-105	374.00
IUUC-Ogu-078830	Oryza glumaepatula	66.30	1.00e-105	375.00
IUUC-Oin-079150	Oryza indica	66.30	8.00e-106	376.00
IUUC-Olo-080398	Oryza longistaminata	57.98	8.00e-82	296.00
IUUC-Ome-081544	Oryza meridionalis	54.28	9.00e-89	319.00
IUUC-Oni-082250	Oryza nivara	66.30	8.00e-106	376.00
IUUC-Opu-083638	Oryza punctata	64.56	7.00e-106	376.00
IUUC-Oru-084981	Oryza rufipogon	66.30	5.00e-106	377.00
IUUC-Osa-085961	Oryza sativa	66.30	5.00e-106	377.00
IUUC-Olu-087880	Ostreococcus lucimarinus	68.77	9.00e-113	399.00
IUUC-Oga-088891	Otolemur garnettii	87.05	0.00e+00	688.00
IUUC-Oar-090021	Ovis aries	87.13	0.00e+00	690.00
IUUC-Ptr-091458	Pan troglodytes	87.62	0.00e+00	723.00
IUUC-Pan-092546	Papio anubis	86.63	0.00e+00	656.00
IUUC-Psi-093280	Pelodiscus sinensis	72.82	5.00e-162	563.00
IUUC-Pma-094298	Petromyzon marinus	78.11	3.00e-122	431.00
IUUC-Pno-094847	Phaeosphaeria nodorum	60.31	4.00e-89	321.00
IUUC-Ppa-095855	Physcomitrella patens	60.76	2.00e-106	378.00
IUUC-Pfo-096428	Poecilia formosa	62.22	1.00e-129	456.00
IUUC-Pab-098696	Pongo abelii	86.42	0.00e+00	707.00
IUUC-Pop-099405	Populus trichocarpa	62.07	6.00e-106	376.00
IUUC-Pca-100740	Procavia capensis	80.20	0.00e+00	662.00
IUUC-Ppe-101854	Prunus persica	62.54	4.00e-106	377.00
IUUC-Pva-103212	Pteropus vampyrus	84.46	0.00e+00	671.00
IUUC-Pgr-103474	Puccinia graminis	59.22	1.00e-97	349.00
IUUC-Ptt-103933	Puccinia triticina	47.49	3.00e-60	224.00
IUUC-Pte-104089	Pyrenophora teres	49.57	4.00e-88	318.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	49.41	4.00e-88	318.00
IUUC-Rno-105057	Rattus norvegicus	82.59	0.00e+00	660.00
IUUC-Sha-107137	Sarcophilus harrisii	78.04	2.00e-176	611.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	59.56	4.00e-98	351.00
IUUC-Spo-108078	Schizosaccharomyces pombe	61.39	1.00e-98	353.00
IUUC-Smo-109288	Selaginella moellendorffii	65.92	3.00e-106	377.00
IUUC-Sit-110246	Setaria italica	64.06	7.00e-105	373.00
IUUC-Sly-111379	Solanum lycopersicum	64.41	7.00e-107	380.00
IUUC-Stu-112777	Solanum tuberosum	61.17	7.00e-106	376.00
IUUC-Sbi-114325	Sorghum bicolor	63.70	9.00e-105	372.00
IUUC-Sre-115203	Sporisorium reilianum	57.74	2.00e-79	289.00
IUUC-Ssc-115361	Sus scrofa	85.11	0.00e+00	697.00
IUUC-Tgu-116967	Taeniopygia guttata	70.78	6.00e-149	520.00
IUUC-Tru-117570	Takifugu rubripes	62.41	6.00e-136	476.00
IUUC-Tsy-119280	Tarsius syrichta	90.65	4.00e-116	411.00
IUUC-Tni-120721	Tetraodon nigroviridis	62.53	1.00e-135	476.00
IUUC-Tca-121494	Theobroma cacao	61.81	2.00e-105	375.00
IUUC-Tre-121869	Trichoderma reesei	54.63	2.00e-92	332.00
IUUC-Tvi-122510	Trichoderma virens	57.60	1.00e-91	330.00
IUUC-Tae-123071	Triticum aestivum	64.16	9.00e-105	372.00
IUUC-Tur-126240	Triticum urartu	64.16	3.00e-104	371.00
IUUC-Tme-126921	Tuber melanosporum	61.78	2.00e-94	339.00
IUUC-Tbe-127872	Tupaia belangeri	80.67	1.00e-179	622.00
IUUC-Ttr-129134	Tursiops truncatus	87.31	0.00e+00	669.00
IUUC-Uma-129412	Ustilago maydis	56.00	7.00e-78	284.00
IUUC-Vda-130003	Verticillium dahliae	51.88	1.00e-90	326.00
IUUC-Vvi-131272	Vitis vinifera	65.44	1.00e-105	375.00
IUUC-Xtr-132019	Xenopus tropicalis	65.67	4.00e-150	524.00
IUUC-Xma-134203	Xiphophorus maculatus	61.10	5.00e-132	464.00
IUUC-Yli-134503	Yarrowia lipolytica	46.69	4.00e-86	311.00
IUUC-Zma-135232	Zea mays	63.21	9.00e-104	369.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence