iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001744

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01000443

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000002210.1	ENSAMET00000002419.1	ENSAMEP00000002322.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.30e-81	271.9	368	837

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCY+NS+LQ+L++ +++r+++l+     l e+    ++++l+++lq lf+ l +s++ a+sp+++l+a +   + fs   qq
   Q: 368  GLINLGNTCYVNSILQALFMASDFRHCVLR-----LTEN----NSQPLMTKLQWLFAFLEHSQRPAISPENFLSASW--TPWFSPGTQQ 445
           9*****************************.....4433....3579***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee      k+ ++ +++ k+++  + + ++++ +++ ++++F+g++ ++i+cl+c nvssree f+dlsl++p  
   Q: 446  DCSEYLKYLLDRLHEEE-----KTGTRICQKLKQSSLPSPPGEPPSPSPTSVEKMFGGKIVTRIRCLRCLNVSSREEAFTDLSLAFPPT 529
           *****************.....667777777777777888999********************************************** PP
   S: 180  eetkke................................................................................... 185
           e +  +                                                                                   
   Q: 530  ERCRRRrlgsvmlpaedlggrdppppspaqvpsrvgprrqrkhcvtvsppsvldieglgpqgrggqssgeekvekeeeveeeaqeeert 618
           *998889********************************************************************************** PP
   S: 186  ....................................................slqdcLesftkeeelegenkyycekckkkqeaekklk 222
                                                               s+ d+ + f ++e+l+ en+yyce c ++q+aek ++
   Q: 619  qeeeeeeekekeeeeekaekekeaettkekeedgpepgshrgaaapagegsrSVLDLVNYFLSPERLTAENRYYCEPCASLQDAEKAVE 707
           ***************************************************************************************** PP
   S: 223  lkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn......... 301
           l++ P++Lil L Rfsf+ + ++r+ki + v +pl L l     +        + Y L++vvvHsG s++sGHY++y+++         
   Q: 708  LSQGPRYLILTLLRFSFDLRSMRRRKILDDVAIPLLLRLPLAGGR-------GQAYGLCSVVVHSGvSSESGHYYCYAREgaarpapsl 789
           **********************************99999855555.......89**************************999999999 PP
   S: 302  .......ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                   +++W+lf+D++V+ ++ e+v + t+    +taYvlfY++r
   Q: 790  gaadrpePEHQWYLFNDTRVSFSSFESVSNVTSffpkDTAYVLFYRQR 837
           99998888999*******************999************985 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MDKILEAVVT SSYPASVKQG LVRRVLEAAR HLEREQCLAL LALGARLYVS GADELPPVCE 60
RPGPAVCAQV ARLLARHPRC VPDGPHRLLF CQQLVRCLGR FRCPAEGEEG AVEFLEQAQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCCTGGAGGC GGTGGTGACG TCCTCGTACC CCGCGAGCGT GAAGCAGGGG 60
CTGGTGCGGC GCGTGCTGGA GGCGGCGCGG CACGCTGGAG CGGGAGCAGT GCCTGGCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005070	Anolis carolinensis	67.03	1.00e-171	596.00
IUUC-Bta-012545	Bos taurus	91.16	0.00e+00	967.00
IUUC-Cja-019731	Callithrix jacchus	93.16	0.00e+00	980.00
IUUC-Cfa-020095	Canis familiaris	92.01	0.00e+00	1368.00
IUUC-Cpo-021961	Cavia porcellus	91.98	0.00e+00	950.00
IUUC-Csa-023167	Chlorocebus sabaeus	92.28	0.00e+00	961.00
IUUC-Dno-029186	Dasypus novemcinctus	83.33	0.00e+00	808.00
IUUC-Dor-030538	Dipodomys ordii	99.00	0.00e+00	820.00
IUUC-Dme-031871	Drosophila melanogaster	31.68	1.00e-45	178.00
IUUC-Ete-032512	Echinops telfairi	90.51	7.00e-106	377.00
IUUC-Eca-033279	Equus caballus	97.66	0.00e+00	896.00
IUUC-Eeu-035120	Erinaceus europaeus	69.89	0.00e+00	665.00
IUUC-Fca-035969	Felis catus	92.36	0.00e+00	1275.00
IUUC-Ggo-045323	Gorilla gorilla	89.15	0.00e+00	974.00
IUUC-Hsa-046124	Homo sapiens	93.33	0.00e+00	963.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	94.43	0.00e+00	984.00
IUUC-Laf-053999	Loxodonta africana	90.24	0.00e+00	944.00
IUUC-Mcc-055266	Macaca mulatta	91.03	0.00e+00	944.00
IUUC-Meu-056906	Macropus eugenii	80.37	0.00e+00	863.00
IUUC-Mmr-061720	Microcebus murinus	92.79	0.00e+00	715.00
IUUC-Mdo-062167	Monodelphis domestica	79.93	0.00e+00	855.00
IUUC-Mmu-063298	Mus musculus	90.37	0.00e+00	957.00
IUUC-Mpu-066195	Mustela putorius furo	95.10	0.00e+00	1316.00
IUUC-Mlu-067583	Myotis lucifugus	85.89	0.00e+00	1095.00
IUUC-Opr-070454	Ochotona princeps	91.16	2.00e-100	360.00
IUUC-Ocu-074121	Oryctolagus cuniculus	86.04	0.00e+00	799.00
IUUC-Oga-088593	Otolemur garnettii	93.35	0.00e+00	956.00
IUUC-Oar-090140	Ovis aries	90.43	0.00e+00	952.00
IUUC-Pan-092168	Papio anubis	92.46	0.00e+00	963.00
IUUC-Pab-097614	Pongo abelii	92.46	0.00e+00	958.00
IUUC-Pca-100683	Procavia capensis	87.41	0.00e+00	911.00
IUUC-Pva-103146	Pteropus vampyrus	85.16	0.00e+00	873.00
IUUC-Rno-105061	Rattus norvegicus	85.94	0.00e+00	1353.00
IUUC-Sha-106686	Sarcophilus harrisii	78.21	0.00e+00	842.00
IUUC-Tsy-119505	Tarsius syrichta	79.65	3.00e-171	595.00
IUUC-Tbe-127723	Tupaia belangeri	89.19	8.00e-92	331.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence