iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067583

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02022798

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000015951.2	ENSMLUT00000015959.2	ENSMLUP00000014538.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.40e-83	278.8	443	908

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCY+NS+LQ+L++ +++r+++l+     l e+    ++++l+++lq lf+ l +s++ a+sp+++l+a +   + fs  +qq
   Q: 443  GLINLGNTCYVNSILQALFMASDFRHCVLR-----LTEN----NSQPLMTKLQWLFAFLEHSQRPAISPENFLSASW--TPWFSPGAQQ 520
           9*****************************.....4433....3579***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee      k+ ++ +++ k+++s + +e+++  +++ ++++F+g++ ++i cl+c nvssree f+dlsl++p  
   Q: 521  DCSEYLKYLLDRLHEEE-----KTGTRICQKLKQSSSPSPPEEPPGPSSTSVEKMFGGKIVTRICCLRCLNVSSREEAFTDLSLAFPPP 604
           *****************.....67888888888899999999*********************************************99 PP
   S: 180  eetkke................................................................................... 185
           e + ++                                                                                   
   Q: 605  ECCRHRrlgsvvlpaegvgapespppspaqvqgragpqrqrkhcitgavpptildmgglgsqgpgersqekveeeeeekgmeeevrkek 693
           9998889********************************************************************************** PP
   S: 186  ................................................slqdcLesftkeeelegenkyycekckkkqeaekklklkkl 226
                                                           s+ d+ + f ++e+le+en+yyce+c ++qeaek ++l++ 
   Q: 694  eegrtkeeeeeegekvvgeekkvekrendsaspgpetpraapsgegsrSVLDLVNYFLSPERLEEENRYYCESCASLQEAEKVVELSQG 782
           ***************************************************************************************** PP
   S: 227  PevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn............. 301
           P++Lil L Rfsf+ ++++r+ki + v +pl L l     +        + Y+L++vvvHsG s++sGHY++y+++             
   Q: 783  PRYLILTLLRFSFDLRTMRRRKILEDVAVPLLLRLPLAGGR-------AQAYDLCSVVVHSGvSSESGHYYCYAREgaarpapslgaad 864
           ******************************99999855555.......89**************************9999999999999 PP
   S: 302  ...ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
               +++W+lf+D++V+ ++ e+v + t+    +taYvlfY++r
   Q: 865  rpePEHQWYLFNDTRVSFSSFESVSNVTSffpkDTAYVLFYRQR 908
           8888999*******************999************985 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MDKILEAVVM SSYPASVKQG LVRRVLEAAR QPDREQCLAL LALGAAPPTW DGANKLPPPR 60
GCQLVARRRX SRLSSERLLA ELWHAQPPPS CPASRSCSPS SLAQVGVRLL GGWGWGRREL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCCTCGAGGC CGTGGTGATG TCCTCGTACC CGGCCAGCGT GAAACAAGGG 60
CTGGTGCGGC GCGTGTTGGA AGCGGCGCGG CAGCCCCCTG GGACCGCGAG CAGTGCCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001744	Ailuropoda melanoleuca	85.89	0.00e+00	1139.00
IUUC-Apl-004121	Anas platyrhynchos	60.05	0.00e+00	825.00
IUUC-Aca-005070	Anolis carolinensis	65.35	8.00e-168	583.00
IUUC-Bta-012545	Bos taurus	89.25	0.00e+00	776.00
IUUC-Cja-019731	Callithrix jacchus	71.89	0.00e+00	816.00
IUUC-Cfa-020095	Canis familiaris	73.10	0.00e+00	838.00
IUUC-Cpo-021961	Cavia porcellus	68.24	0.00e+00	915.00
IUUC-Csa-023167	Chlorocebus sabaeus	71.64	0.00e+00	793.00
IUUC-Dno-029186	Dasypus novemcinctus	74.55	1.00e-173	603.00
IUUC-Dor-030538	Dipodomys ordii	93.29	9.00e-178	617.00
IUUC-Dme-031871	Drosophila melanogaster	34.06	1.00e-43	171.00
IUUC-Ete-032512	Echinops telfairi	86.17	4.00e-99	355.00
IUUC-Eca-033279	Equus caballus	87.88	0.00e+00	697.00
IUUC-Eeu-035120	Erinaceus europaeus	66.45	2.00e-154	540.00
IUUC-Fca-035969	Felis catus	89.25	0.00e+00	787.00
IUUC-Fal-037625	Ficedula albicollis	59.57	0.00e+00	847.00
IUUC-Gga-040767	Gallus gallus	59.37	0.00e+00	862.00
IUUC-Ggo-045323	Gorilla gorilla	88.25	0.00e+00	754.00
IUUC-Hsa-046124	Homo sapiens	72.54	0.00e+00	802.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	73.14	0.00e+00	1196.00
IUUC-Lch-049513	Latimeria chalumnae	57.22	0.00e+00	765.00
IUUC-Laf-053999	Loxodonta africana	71.08	0.00e+00	1137.00
IUUC-Mcc-055266	Macaca mulatta	70.70	0.00e+00	775.00
IUUC-Meu-056906	Macropus eugenii	76.97	0.00e+00	711.00
IUUC-Mmr-061720	Microcebus murinus	93.30	0.00e+00	716.00
IUUC-Mmu-063298	Mus musculus	71.33	0.00e+00	1216.00
IUUC-Mpu-066195	Mustela putorius furo	84.43	0.00e+00	1046.00
IUUC-Ocu-074121	Oryctolagus cuniculus	65.20	0.00e+00	638.00
IUUC-Oga-088593	Otolemur garnettii	91.30	0.00e+00	762.00
IUUC-Oar-090140	Ovis aries	84.68	0.00e+00	764.00
IUUC-Pan-092168	Papio anubis	71.78	0.00e+00	795.00
IUUC-Pab-097614	Pongo abelii	71.64	0.00e+00	789.00
IUUC-Pca-100683	Procavia capensis	68.53	0.00e+00	762.00
IUUC-Pva-103146	Pteropus vampyrus	79.91	0.00e+00	721.00
IUUC-Rno-105061	Rattus norvegicus	71.28	0.00e+00	1198.00
IUUC-Sha-106686	Sarcophilus harrisii	78.65	0.00e+00	691.00
IUUC-Ssc-116003	Sus scrofa	86.96	4.00e-91	328.00
IUUC-Tgu-117024	Taeniopygia guttata	61.64	0.00e+00	868.00
IUUC-Tsy-119505	Tarsius syrichta	79.35	2.00e-169	589.00
IUUC-Tbe-127723	Tupaia belangeri	90.43	9.00e-89	321.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence