iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022003

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02047323

Gene Name

SOCS3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000004247.3	ENSCPOT00000004292.2	ENSCPOP00000017841.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	91.23	3.00e-106	381.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MVTHSKFPAA GMSRPLDTSL RLKTFSSKSE YQLVVNAVRK LQESGFYWSA VTGGEANLLL 60
SAEPAGTFLI RDSSDQRHFF TLSVKTQSGT KNLRIQCEGG SFSLQSDPRS TQPVPRFDCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTCACCC ACAGCAAGTT TCCCGCCGCC GGGATGAGCC GTCCCTTGGA CACTAGCCTG 60
CGCCTCAAGA CCTTCAGCTC CAAGAGCGAG TACCAGCTGG TGGTGAACGC AGTGCGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0060670--P:branching involved in labyrinthine layer morphogenesis
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0050728--P:negative regulation of inflammatory response
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0060674--P:placenta blood vessel development
GO:0045597--P:positive regulation of cell differentiation
GO:0016567--P:protein ubiquitination
GO:0060708--P:spongiotrophoblast differentiation
GO:0060707--P:trophoblast giant cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	89.91	6.00e-106	376.00
IUUC-Apl-003607	Anas platyrhynchos	81.14	6.00e-95	339.00
IUUC-Aca-005063	Anolis carolinensis	80.35	2.00e-102	364.00
IUUC-Ath-006990	Arabidopsis thaliana	32.94	1.60e-02	35.00
IUUC-Ame-010859	Astyanax mexicanus	55.36	6.00e-70	256.00
IUUC-Bta-012817	Bos taurus	89.52	4.00e-108	383.00
IUUC-Cja-019605	Callithrix jacchus	90.79	4.00e-106	377.00
IUUC-Cfa-021231	Canis familiaris	91.23	1.00e-107	382.00
IUUC-Csa-023511	Chlorocebus sabaeus	91.23	1.00e-106	378.00
IUUC-Dre-028536	Danio rerio	58.80	2.00e-73	268.00
IUUC-Dno-029003	Dasypus novemcinctus	87.28	5.00e-107	379.00
IUUC-Eca-034205	Equus caballus	82.12	3.00e-68	250.00
IUUC-Fca-036317	Felis catus	89.82	3.00e-103	367.00
IUUC-Gmo-038777	Gadus morhua	63.89	6.00e-36	142.00
IUUC-Gga-041258	Gallus gallus	80.70	3.00e-95	340.00
IUUC-Gac-041837	Gasterosteus aculeatus	54.74	1.00e-64	238.00
IUUC-Ggo-045620	Gorilla gorilla	91.23	1.00e-106	378.00
IUUC-Hsa-046909	Homo sapiens	91.23	1.00e-106	378.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	87.61	3.00e-106	377.00
IUUC-Lch-049510	Latimeria chalumnae	66.81	2.00e-83	301.00
IUUC-Loc-052863	Lepisosteus oculatus	62.23	4.00e-79	286.00
IUUC-Laf-054136	Loxodonta africana	94.30	3.00e-108	384.00
IUUC-Mcc-055383	Macaca mulatta	91.23	1.00e-106	378.00
IUUC-Meu-056153	Macropus eugenii	88.60	2.00e-105	374.00
IUUC-Mmr-061185	Microcebus murinus	91.23	4.00e-107	380.00
IUUC-Mdo-061819	Monodelphis domestica	88.16	8.00e-107	379.00
IUUC-Mmu-064231	Mus musculus	93.86	2.00e-109	387.00
IUUC-Mpu-066691	Mustela putorius furo	91.23	1.00e-107	382.00
IUUC-Mlu-067673	Myotis lucifugus	89.91	8.00e-107	379.00
IUUC-Ont-072406	Oreochromis niloticus	53.88	4.00e-67	247.00
IUUC-Oan-073249	Ornithorhynchus anatinus	73.68	2.00e-93	334.00
IUUC-Ocu-074935	Oryctolagus cuniculus	87.50	3.00e-29	119.00
IUUC-Ola-087373	Oryzias latipes	47.34	4.00e-49	187.00
IUUC-Oga-088041	Otolemur garnettii	89.47	4.00e-107	380.00
IUUC-Oar-089646	Ovis aries	87.34	2.00e-103	367.00
IUUC-Ptr-091502	Pan troglodytes	91.23	1.00e-106	378.00
IUUC-Pan-091934	Papio anubis	91.23	1.00e-106	378.00
IUUC-Pfo-096412	Poecilia formosa	42.24	8.00e-48	182.00
IUUC-Pab-098554	Pongo abelii	91.23	1.00e-106	378.00
IUUC-Rno-105874	Rattus norvegicus	93.86	2.00e-110	391.00
IUUC-Sha-107151	Sarcophilus harrisii	89.04	1.00e-106	378.00
IUUC-Ssc-115722	Sus scrofa	82.29	8.00e-65	238.00
IUUC-Tgu-117151	Taeniopygia guttata	81.58	1.00e-94	338.00
IUUC-Tru-118428	Takifugu rubripes	53.45	1.00e-67	248.00
IUUC-Tni-120590	Tetraodon nigroviridis	53.88	2.00e-66	244.00
IUUC-Ttr-129065	Tursiops truncatus	92.14	2.00e-106	377.00
IUUC-Xtr-132167	Xenopus tropicalis	64.91	9.00e-81	292.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence