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Tag Content
iUUCD ID IUUC-Ptr-090851
Ensembl Protein ID ENSPTRP00000024006.3
UniProt Accession H2QL33; H2QL33_PANTR
Genbank Protein ID JAA01105.1; JAA11586.1; JAA24399.1; JAA39522.1
Protein Name tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4
Genbank Nucleotide ID BS000230; GABF01010559; GABD01008701; GABE01005217
Gene Name WDR4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPTRG00000013948.3 ENSPTRT00000026020.3 ENSPTRP00000024006.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.30e-07 30.9 186 225
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sd..tllvsGsdDgtikvWDlrtgvllk 37
           gHt+ v+ + f  ++  +ll+s+s+Dgt+++W++r+g++l+
   Q: 186  GHTEFVSRI-FvvPTqpGLLLSSSGDGTLRLWEYRSGRQLH 225
           677777777.78944469*******************9986 PP
   
Organism Pan troglodytes
Functional Description
(View)

Functional Description


     Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
 Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
Protein Sequence
(Fasta)
MAGSVGLALC GQTLVVRGGS RFLATSIASS DDDSLFIYDC SAAEKKSQEN KGEDAPLDQG 60
SGAILASTFS KSGSYFALTD DSKRLILFRT KPWQCLSVRT VARRCTALTF IASEEKVLVA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ptr-090851|E3,WD_repeat|Pan troglodytes
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGTCACCGA CCGGTGCGGA CAGGAAGAGG CTCTGGGCTG GCGCATGTGT ATGGCGGTGA 60
GGCGGGCGGG TACATGGCGG GCTCTGTGGG ACTGGCGTTG TGCGGCCAGA CGCTGGTGGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ptr-090851|E3,WD_repeat|Pan troglodytes
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat
Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
SMART

SM00320--WD40
Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0043527--C:tRNA methyltransferase complex
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000556 Aegilops tauschii 33.74 5.00e-11 62.00
IUUC-Apl-003975 Anas platyrhynchos 59.59 1.00e-120 426.00
IUUC-Aca-005170 Anolis carolinensis 53.93 2.00e-104 372.00
IUUC-Aly-005769 Arabidopsis lyrata 30.24 5.00e-23 102.00
IUUC-Ath-006733 Arabidopsis thaliana 34.87 3.00e-22 99.80
IUUC-Acl-008151 Aspergillus clavatus 34.93 2.00e-15 77.00
IUUC-Afl-008518 Aspergillus flavus 34.25 2.00e-17 82.80
IUUC-Afu-009102 Aspergillus fumigatus 36.47 1.00e-13 71.20
IUUC-Ani-009442 Aspergillus nidulans 25.36 2.00e-14 73.90
IUUC-Aor-010133 Aspergillus oryzae 26.92 1.00e-20 94.40
IUUC-Ate-010465 Aspergillus terreus 37.29 2.00e-14 73.60
IUUC-Ame-010613 Astyanax mexicanus 46.60 2.00e-89 322.00
IUUC-Bgr-012067 Blumeria graminis 45.88 2.00e-18 87.40
IUUC-Bta-012788 Bos taurus 77.97 0.00e+00 632.00
IUUC-Bdi-014458 Brachypodium distachyon 36.92 4.00e-18 85.90
IUUC-Bol-015373 Brassica oleracea 35.87 3.00e-22 100.00
IUUC-Bra-016644 Brassica rapa 37.57 2.00e-22 101.00
IUUC-Cpo-021963 Cavia porcellus 79.10 1.00e-169 588.00
IUUC-Csa-024148 Chlorocebus sabaeus 96.60 0.00e+00 688.00
IUUC-Cne-026834 Cryptococcus neoformans 34.44 2.00e-18 87.40
IUUC-Dre-028427 Danio rerio 47.92 2.00e-90 325.00
IUUC-Dno-028881 Dasypus novemcinctus 69.62 1.00e-158 552.00
IUUC-Dor-030522 Dipodomys ordii 75.06 1.00e-165 575.00
IUUC-Dme-032136 Drosophila melanogaster 32.52 1.00e-24 107.00
IUUC-Fca-035833 Felis catus 73.47 9.00e-167 579.00
IUUC-Fal-037497 Ficedula albicollis 57.29 1.00e-119 422.00
IUUC-Gga-040547 Gallus gallus 56.76 1.00e-124 439.00
IUUC-Gac-041761 Gasterosteus aculeatus 43.88 9.00e-82 296.00
IUUC-Gma-043941 Glycine max 35.48 6.00e-25 108.00
IUUC-Ggo-045340 Gorilla gorilla 99.51 0.00e+00 769.00
IUUC-Hsa-046403 Homo sapiens 98.30 0.00e+00 759.00
IUUC-Hvu-047643 Hordeum vulgare 39.33 4.00e-19 89.00
IUUC-Itr-048103 Ictidomys tridecemlineatus 80.39 7.00e-179 619.00
IUUC-Kpa-049283 Komagataella pastoris 34.59 2.00e-18 86.70
IUUC-Lch-050682 Latimeria chalumnae 48.64 2.00e-106 379.00
IUUC-Lpe-050712 Leersia perrieri 36.32 6.00e-22 98.60
IUUC-Loc-052599 Lepisosteus oculatus 52.09 4.00e-116 411.00
IUUC-Laf-054390 Loxodonta africana 78.45 2.00e-178 618.00
IUUC-Mcc-054747 Macaca mulatta 96.36 0.00e+00 719.00
IUUC-Mtr-058600 Medicago truncatula 38.76 3.00e-23 102.00
IUUC-Mla-059129 Melampsora laricipopulina 26.15 2.00e-12 66.60
IUUC-Mga-059876 Meleagris gallopavo 57.22 2.00e-123 435.00
IUUC-Mvi-060359 Microbotryum violaceum 28.80 2.00e-12 67.80
IUUC-Mmr-061518 Microcebus murinus 83.05 0.00e+00 654.00
IUUC-Mac-065625 Musa acuminata 34.39 4.00e-20 92.40
IUUC-Nfi-068402 Neosartorya fischeri 27.72 4.00e-15 75.90
IUUC-Nle-069914 Nomascus leucogenys 95.39 0.00e+00 708.00
IUUC-Ont-071555 Oreochromis niloticus 41.25 4.00e-77 281.00
IUUC-Oan-072951 Ornithorhynchus anatinus 67.61 1.00e-152 532.00
IUUC-Ocu-074679 Oryctolagus cuniculus 81.72 5.00e-171 593.00
IUUC-Oba-075355 Oryza barthii 27.92 2.00e-10 60.50
IUUC-Obr-076769 Oryza brachyantha 32.44 2.00e-23 103.00
IUUC-Ogl-077168 Oryza glaberrima 33.71 8.00e-24 104.00
IUUC-Ogu-078275 Oryza glumaepatula 27.92 1.00e-10 60.80
IUUC-Oin-079207 Oryza indica 33.71 8.00e-24 104.00
IUUC-Oni-082437 Oryza nivara 28.94 1.00e-10 61.20
IUUC-Opu-084031 Oryza punctata 33.82 4.00e-22 99.40
IUUC-Oru-084380 Oryza rufipogon 28.45 2.00e-10 60.50
IUUC-Osa-085327 Oryza sativa 34.26 1.00e-23 104.00
IUUC-Ola-086716 Oryzias latipes 43.68 1.00e-77 283.00
IUUC-Olu-087708 Ostreococcus lucimarinus 29.79 4.00e-14 72.40
IUUC-Oar-090239 Ovis aries 81.12 1.00e-173 602.00
IUUC-Pan-092558 Papio anubis 96.38 0.00e+00 688.00
IUUC-Psi-093792 Pelodiscus sinensis 59.24 1.00e-129 456.00
IUUC-Ppa-095757 Physcomitrella patens 38.82 4.00e-20 92.40
IUUC-Pfo-096465 Poecilia formosa 41.86 1.00e-84 306.00
IUUC-Pab-097722 Pongo abelii 96.84 0.00e+00 740.00
IUUC-Pop-098979 Populus trichocarpa 35.14 5.00e-19 88.60
IUUC-Pca-100753 Procavia capensis 74.74 2.00e-117 415.00
IUUC-Ppe-101515 Prunus persica 33.83 9.00e-19 87.80
IUUC-Sja-107780 Schizosaccharomyces japonicus 26.77 1.00e-14 73.90
IUUC-Spo-108251 Schizosaccharomyces pombe 29.00 8.00e-13 68.20
IUUC-Smo-108938 Selaginella moellendorffii 37.31 2.00e-23 103.00
IUUC-Sit-110020 Setaria italica 35.57 2.00e-21 97.10
IUUC-Sly-111543 Solanum lycopersicum 33.70 3.00e-21 95.90
IUUC-Stu-111925 Solanum tuberosum 32.47 2.00e-21 96.70
IUUC-Sbi-114061 Sorghum bicolor 37.22 3.00e-21 95.90
IUUC-Tgu-117321 Taeniopygia guttata 59.01 3.00e-113 401.00
IUUC-Tru-118454 Takifugu rubripes 43.97 6.00e-80 290.00
IUUC-Tni-119894 Tetraodon nigroviridis 43.64 4.00e-77 281.00
IUUC-Tca-121746 Theobroma cacao 34.65 2.00e-20 94.00
IUUC-Tae-124114 Triticum aestivum 38.76 2.00e-18 87.00
IUUC-Tur-126254 Triticum urartu 34.36 3.00e-12 66.20
IUUC-Tbe-127683 Tupaia belangeri 52.08 6.00e-59 221.00
IUUC-Ttr-129056 Tursiops truncatus 73.61 2.00e-162 565.00
IUUC-Vvi-131428 Vitis vinifera 36.27 1.00e-21 97.40
IUUC-Xma-133605 Xiphophorus maculatus 42.16 2.00e-85 309.00
Created Date 25-Jun-2017

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