iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-124114

Ensembl Protein ID

TRIAE_CS42_5DL_TGACv1_434937_AA1443850.1

UniProt Accession

W5FZP8; W5FZP8_WHEAT

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit; WD repeat-containing protein 4 homolog

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_5DL_TGACv1_434937_AA1443850	TRIAE_CS42_5DL_TGACv1_434937_AA1443850.1	TRIAE_CS42_5DL_TGACv1_434937_AA1443850.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.10e-14	54.4	200	240

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd..tllvsGsdDgtikvWDlrtgvll 36
           gHt+ v+++af   s+   +l+sG++D ++++WD+ tg ll
   Q: 200  GHTEFVSSIAFtshSGgsSFLLSGGGDSSVRLWDYITGCLL 240
           89**********99333589**************9998876 PP

Organism

Triticum aestivum

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

MEDAAVEEAE VSGAGEFAPA LVAAHPLGNS VAVAVGPELR VFDLKGGCAV SLSDDSGGCS 60
HSDAIRAISF SADGALFASA GDDKLVKIWK TDSWRCIQTI TSEKRVSAVA ISKDGLYVTF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATCCACACA CTCTCTAACG TTTCCCTCAG AAAGAGAAAA ATAGAACTAC ACTGGCCACC 60
GGGTCCCACG AAGAGCCGGC CATAAACCCT AGCAATTTCC CCACTCCCGA GCTCCCTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0036265--P:RNA (guanine-N7)-methylation
GO:0030488--P:tRNA methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	95.12	0.00e+00	724.00
IUUC-Ame-010613	Astyanax mexicanus	32.12	5.00e-24	105.00
IUUC-Bgr-012067	Blumeria graminis	32.00	8.00e-15	75.90
IUUC-Bta-012788	Bos taurus	31.45	2.00e-26	113.00
IUUC-Csa-024148	Chlorocebus sabaeus	39.33	3.00e-18	87.00
IUUC-Cne-026834	Cryptococcus neoformans	31.20	3.00e-18	87.40
IUUC-Dme-032136	Drosophila melanogaster	29.46	5.00e-15	76.30
IUUC-Gma-043722	Glycine max	53.05	1.00e-110	393.00
IUUC-Ggo-045340	Gorilla gorilla	38.93	3.00e-17	83.20
IUUC-Hsa-046403	Homo sapiens	40.00	8.00e-19	88.60
IUUC-Itr-048103	Ictidomys tridecemlineatus	33.20	1.00e-26	114.00
IUUC-Mcc-054747	Macaca mulatta	39.33	2.00e-18	87.00
IUUC-Mtr-058600	Medicago truncatula	52.63	7.00e-114	404.00
IUUC-Mga-059876	Meleagris gallopavo	28.62	2.00e-21	97.40
IUUC-Nle-069914	Nomascus leucogenys	37.33	5.00e-15	76.30
IUUC-Oan-072951	Ornithorhynchus anatinus	30.86	7.00e-25	108.00
IUUC-Ocu-074679	Oryctolagus cuniculus	30.43	9.00e-21	95.10
IUUC-Olu-087708	Ostreococcus lucimarinus	28.86	2.00e-37	150.00
IUUC-Oar-090239	Ovis aries	31.45	5.00e-26	112.00
IUUC-Ptr-090851	Pan troglodytes	39.60	1.00e-17	84.70
IUUC-Pan-092558	Papio anubis	39.33	3.00e-18	87.00
IUUC-Pab-097722	Pongo abelii	38.41	1.00e-17	84.70
IUUC-Sja-107780	Schizosaccharomyces japonicus	25.14	3.00e-20	93.60

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence