iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000043484.6	ENSDART00000159593.1	ENSDARP00000135223.1
ENSDARG00000043484.6	ENSDART00000063837.5	ENSDARP00000063836.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.90e-56	190.0	5	139
UBD/UBC-like/UBD_UBC	1.20e-84	282.2	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++l +dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  
   Q: 5    RIHKELHDLGRDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR-- 90
           99**********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wspal++++vllsi+sll++pnp++pl  e+a+++k++re+y++++r
   Q: 91   SQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAR 139
           *********************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           ri+kel+dl rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqw
   Q: 5    RIHKELHDLGRDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQW 93
           8**************************************************************************************** PP
   S: 90   saaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           s+alt+skvlls+csll+d++pddplv+eiariyktd+eky+riarewt
   Q: 94   SPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWT 142
           ************************************************8 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MALKRIHKEL HDLGRDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCGTAATT CACAACAGCA CTATCTGGCA ACTGGCGTAG GCGCGCAATC CGTCCCCGGC 60
GACTGCGTCC ATTGGCGGAA GGATCTGTTT AGAGCAGCGC AGTGTGCGTG TTGCGGTTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

KEGG

dre:393934

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001778	Ailuropoda melanoleuca	98.57	2.00e-80	290.00
IUUC-Apl-004043	Anas platyrhynchos	93.20	1.00e-80	291.00
IUUC-Aca-005236	Anolis carolinensis	98.64	6.00e-85	305.00
IUUC-Ago-007967	Ashbya gossypii	80.95	2.00e-71	260.00
IUUC-Ang-009725	Aspergillus niger	84.80	7.00e-62	229.00
IUUC-Aor-010157	Aspergillus oryzae	85.03	6.00e-74	269.00
IUUC-Bgr-012238	Blumeria graminis	80.95	3.00e-70	256.00
IUUC-Bta-013158	Bos taurus	98.64	6.00e-85	305.00
IUUC-Cel-018362	Caenorhabditis elegans	94.56	5.00e-82	296.00
IUUC-Cja-019886	Callithrix jacchus	98.64	6.00e-85	305.00
IUUC-Cfa-020436	Canis familiaris	98.64	6.00e-85	305.00
IUUC-Cpo-021714	Cavia porcellus	96.60	3.00e-83	300.00
IUUC-Csa-023148	Chlorocebus sabaeus	93.92	9.00e-80	288.00
IUUC-Csv-026311	Ciona savignyi	85.62	8.00e-73	265.00
IUUC-Cne-026957	Cryptococcus neoformans	80.82	3.00e-70	256.00
IUUC-Dno-028952	Dasypus novemcinctus	98.57	9.00e-81	291.00
IUUC-Dme-031594	Drosophila melanogaster	95.24	5.00e-82	296.00
IUUC-Ete-032295	Echinops telfairi	98.56	4.00e-80	289.00
IUUC-Eca-033293	Equus caballus	98.56	2.00e-80	290.00
IUUC-Eeu-034766	Erinaceus europaeus	95.71	2.00e-77	280.00
IUUC-Fca-035917	Felis catus	96.60	2.00e-83	300.00
IUUC-Fal-036904	Ficedula albicollis	97.14	1.00e-79	288.00
IUUC-Gmo-038898	Gadus morhua	96.50	1.00e-80	291.00
IUUC-Ggr-039912	Gaeumannomyces graminis	80.26	4.00e-70	256.00
IUUC-Gga-040758	Gallus gallus	98.64	6.00e-85	305.00
IUUC-Gac-042231	Gasterosteus aculeatus	95.92	8.00e-83	298.00
IUUC-Ggo-045375	Gorilla gorilla	94.59	3.00e-81	293.00
IUUC-Hsa-045885	Homo sapiens	98.64	6.00e-85	305.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	95.27	4.00e-81	293.00
IUUC-Laf-053580	Loxodonta africana	98.57	1.00e-80	291.00
IUUC-Meu-056462	Macropus eugenii	95.68	5.00e-78	282.00
IUUC-Mpo-057596	Magnaporthe poae	80.26	9.00e-70	255.00
IUUC-Mla-059189	Melampsora laricipopulina	81.63	3.00e-69	253.00
IUUC-Mga-059237	Meleagris gallopavo	97.14	1.00e-79	288.00
IUUC-Mvi-060397	Microbotryum violaceum	82.99	1.00e-72	264.00
IUUC-Mmr-060889	Microcebus murinus	95.92	4.00e-83	299.00
IUUC-Mdo-062962	Monodelphis domestica	98.64	6.00e-85	305.00
IUUC-Mmu-063518	Mus musculus	98.64	6.00e-85	305.00
IUUC-Mpu-066604	Mustela putorius furo	94.52	3.00e-81	293.00
IUUC-Ncr-068677	Neurospora crassa	83.67	9.00e-73	265.00
IUUC-Opr-070191	Ochotona princeps	97.12	4.00e-79	286.00
IUUC-Ont-071766	Oreochromis niloticus	97.28	5.00e-84	302.00
IUUC-Ocu-074315	Oryctolagus cuniculus	98.64	6.00e-85	305.00
IUUC-Ola-086331	Oryzias latipes	97.28	5.00e-84	302.00
IUUC-Oga-088477	Otolemur garnettii	93.84	4.00e-81	293.00
IUUC-Oar-090038	Ovis aries	96.60	2.00e-83	300.00
IUUC-Ptr-090707	Pan troglodytes	98.64	6.00e-85	305.00
IUUC-Pan-092143	Papio anubis	98.64	6.00e-85	305.00
IUUC-Psi-094076	Pelodiscus sinensis	96.60	2.00e-83	300.00
IUUC-Pma-094405	Petromyzon marinus	94.81	2.00e-75	274.00
IUUC-Pfo-096753	Poecilia formosa	97.28	5.00e-84	302.00
IUUC-Pab-097764	Pongo abelii	98.64	6.00e-85	305.00
IUUC-Pgr-103381	Puccinia graminis	83.67	4.00e-71	260.00
IUUC-Ptt-103723	Puccinia triticina	79.29	9.00e-63	232.00
IUUC-Rno-105498	Rattus norvegicus	96.60	2.00e-83	300.00
IUUC-Sja-107729	Schizosaccharomyces japonicus	85.03	1.00e-73	268.00
IUUC-Spo-108032	Schizosaccharomyces pombe	85.03	9.00e-74	268.00
IUUC-Sar-113302	Sorex araneus	98.56	4.00e-80	289.00
IUUC-Sre-115037	Sporisorium reilianum	81.25	2.00e-70	257.00
IUUC-Tgu-116727	Taeniopygia guttata	96.60	2.00e-83	300.00
IUUC-Tru-118272	Takifugu rubripes	97.28	1.00e-83	301.00
IUUC-Tni-120056	Tetraodon nigroviridis	97.28	1.00e-83	301.00
IUUC-Tre-122125	Trichoderma reesei	82.99	6.00e-72	262.00
IUUC-Tvi-122296	Trichoderma virens	82.99	6.00e-72	262.00
IUUC-Tme-126912	Tuber melanosporum	82.31	4.00e-72	263.00
IUUC-Tbe-127609	Tupaia belangeri	100.00	2.00e-67	247.00
IUUC-Uma-129648	Ustilago maydis	82.31	3.00e-72	263.00
IUUC-Vpa-130446	Vicugna pacos	97.86	3.00e-79	288.00
IUUC-Xtr-132329	Xenopus tropicalis	98.64	6.00e-85	305.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence