iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004386

UUCD1 version

UUC-AnC-00156

Ensembl Protein ID

ENSACAP00000015653.2

UniProt Accession

H9GMR4; H9GMR4_ANOCA

Protein Name

Uncharacterized protein

Gene Name

SH3RF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000015860.3	ENSACAT00000015968.3	ENSACAP00000015653.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.30e-08	33.9	12	53
UBD/SH3	4.40e-48	161.0	443	498

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Cl  +     ss++e rCP Cr
   Q: 12   CPVCLERLDASAKVLPCQHTFCKRCLLGI----VSSRNELRCPECR 53
           **********9**************9777....89**********8 PP

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           + +++y+y + ++deL+l+kG++ lv  + +   gW kg++  + k G+fP n+v+ +
   Q: 443  VYIAIYPYVPRKEDELELRKGEMFLVF-ERC-QDGWFKGTSMHTSKIGVFPGNYVAPV 498
           5789**********************9.555.569********************988 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MDESALLDLL ECPVCLERLD ASAKVLPCQH TFCKRCLLGI VSSRNELRCP ECRTLVDCSV 60
DELPSNILLV RLLDGIKQRP WKPGGLVSST NSLRSQTSTV ANCIPKDLQS SQSVQQQRVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTGGGATAG AGGGCTGTGT GGAAGAAGCG AGGAGGAAGC GGATTCAAAA CATGAGCCTG 60
TTCTCCATTT TTTCAAACCA AGACAGTCCT GAGAGGAAGG AAGGAAGGTT GGGCGGGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0046328--P:regulation of JNK cascade

KEGG

acs:100553389

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	75.03	0.00e+00	1139.00
IUUC-Apl-003961	Anas platyrhynchos	82.74	0.00e+00	1264.00
IUUC-Ame-010659	Astyanax mexicanus	59.26	0.00e+00	882.00
IUUC-Bta-012563	Bos taurus	58.11	2.00e-115	409.00
IUUC-Cja-019730	Callithrix jacchus	74.83	0.00e+00	1140.00
IUUC-Cfa-020992	Canis familiaris	75.85	0.00e+00	1174.00
IUUC-Cpo-021304	Cavia porcellus	75.03	0.00e+00	1199.00
IUUC-Csa-023925	Chlorocebus sabaeus	75.79	0.00e+00	1146.00
IUUC-Cho-024630	Choloepus hoffmanni	67.17	0.00e+00	743.00
IUUC-Cin-025274	Ciona intestinalis	47.73	4.00e-73	267.00
IUUC-Csv-026136	Ciona savignyi	42.70	3.00e-73	268.00
IUUC-Cme-027278	Cyanidioschyzon merolae	42.55	3.00e-08	53.50
IUUC-Dre-028290	Danio rerio	61.14	0.00e+00	909.00
IUUC-Dno-029083	Dasypus novemcinctus	78.99	0.00e+00	912.00
IUUC-Dor-030388	Dipodomys ordii	84.55	8.00e-169	587.00
IUUC-Dme-032207	Drosophila melanogaster	47.39	3.00e-65	243.00
IUUC-Ete-032809	Echinops telfairi	68.31	0.00e+00	758.00
IUUC-Eca-034185	Equus caballus	75.56	0.00e+00	983.00
IUUC-Eeu-034816	Erinaceus europaeus	66.52	0.00e+00	952.00
IUUC-Fca-036439	Felis catus	70.94	0.00e+00	1175.00
IUUC-Fal-037074	Ficedula albicollis	82.34	0.00e+00	1257.00
IUUC-Gmo-039443	Gadus morhua	60.27	5.00e-122	431.00
IUUC-Ggr-040119	Gaeumannomyces graminis	43.10	6.00e-12	66.60
IUUC-Gga-040749	Gallus gallus	81.49	0.00e+00	1217.00
IUUC-Gac-041420	Gasterosteus aculeatus	63.67	0.00e+00	655.00
IUUC-Ggo-045215	Gorilla gorilla	75.99	0.00e+00	1168.00
IUUC-Hsa-046315	Homo sapiens	75.56	0.00e+00	1160.00
IUUC-Lch-049453	Latimeria chalumnae	71.66	0.00e+00	922.00
IUUC-Loc-052248	Lepisosteus oculatus	35.90	2.00e-75	276.00
IUUC-Laf-053651	Loxodonta africana	75.45	0.00e+00	1139.00
IUUC-Mcc-054688	Macaca mulatta	75.39	0.00e+00	1136.00
IUUC-Meu-056291	Macropus eugenii	67.64	0.00e+00	743.00
IUUC-Mor-056932	Magnaporthe oryzae	41.67	4.00e-12	67.40
IUUC-Mpo-057322	Magnaporthe poae	43.10	6.00e-12	67.00
IUUC-Mga-059944	Meleagris gallopavo	81.94	0.00e+00	1265.00
IUUC-Mmr-061553	Microcebus murinus	74.60	0.00e+00	1103.00
IUUC-Mdo-062313	Monodelphis domestica	72.40	0.00e+00	1115.00
IUUC-Mmu-063516	Mus musculus	75.64	0.00e+00	1184.00
IUUC-Mpu-066064	Mustela putorius furo	74.89	0.00e+00	1145.00
IUUC-Mlu-067312	Myotis lucifugus	72.88	0.00e+00	1103.00
IUUC-Nle-069035	Nomascus leucogenys	75.87	0.00e+00	1169.00
IUUC-Opr-070690	Ochotona princeps	69.30	2.00e-155	542.00
IUUC-Ont-071484	Oreochromis niloticus	59.51	0.00e+00	866.00
IUUC-Oan-073305	Ornithorhynchus anatinus	77.39	0.00e+00	1184.00
IUUC-Ocu-074936	Oryctolagus cuniculus	74.00	0.00e+00	1150.00
IUUC-Ola-086675	Oryzias latipes	61.44	0.00e+00	629.00
IUUC-Oga-087933	Otolemur garnettii	70.41	0.00e+00	910.00
IUUC-Oar-090408	Ovis aries	58.43	6.00e-108	384.00
IUUC-Ptr-090865	Pan troglodytes	75.90	0.00e+00	1167.00
IUUC-Pan-092362	Papio anubis	75.56	0.00e+00	1143.00
IUUC-Psi-093876	Pelodiscus sinensis	83.85	0.00e+00	1282.00
IUUC-Pfo-097116	Poecilia formosa	60.58	0.00e+00	889.00
IUUC-Pab-098127	Pongo abelii	75.90	0.00e+00	1167.00
IUUC-Pca-100485	Procavia capensis	78.99	0.00e+00	889.00
IUUC-Pva-102661	Pteropus vampyrus	84.93	3.00e-176	612.00
IUUC-Rno-105728	Rattus norvegicus	75.75	0.00e+00	1154.00
IUUC-Sha-106515	Sarcophilus harrisii	79.80	0.00e+00	815.00
IUUC-Sar-113161	Sorex araneus	85.96	5.00e-169	588.00
IUUC-Ssc-115314	Sus scrofa	69.06	0.00e+00	982.00
IUUC-Tgu-117012	Taeniopygia guttata	83.09	0.00e+00	1270.00
IUUC-Tru-118467	Takifugu rubripes	60.55	6.00e-165	574.00
IUUC-Tsy-119566	Tarsius syrichta	72.73	4.00e-153	535.00
IUUC-Tni-120830	Tetraodon nigroviridis	54.52	5.00e-170	591.00
IUUC-Tbe-128070	Tupaia belangeri	76.22	0.00e+00	769.00
IUUC-Ttr-128161	Tursiops truncatus	86.27	9.00e-124	437.00
IUUC-Xtr-132628	Xenopus tropicalis	74.27	0.00e+00	887.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence