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Tag Content
UUCD2 ID IUUC-Aml-001528
UUCD1 version UUC-AiM-00727
Ensembl Protein ID ENSAMEP00000014097.1
UniProt Accession G1M434; G1M434_AILME
Genbank Protein ID ENSAMEP00000014097
Protein Name Uncharacterized protein
Genbank Nucleotide ID ACTA01139411
Gene Name SH3RF1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000013355.1 ENSAMET00000014688.1 ENSAMEP00000014097.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 5.80e-08 33.2 12 53
UBD/SH3 4.60e-48 161.1 444 499
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Cl  +      s++e rCP Cr
   Q: 12   CPVCLERLDASAKVLPCQHTFCKRCLLGI----VGSRNELRCPECR 53
           **********9**************9777....899*********8 PP
   

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +  ++y+y++ ++deL+l+kG++ lv  + +   gW kg++  + k G+fP n+v+ +
   Q: 444  VYVAIYPYTPRKEDELELRKGEMFLVF-ERC-QDGWFKGTSMHTSKIGVFPGNYVAPV 499
           5679**********************9.555.569********************988 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
MDESALLDLL ECPVCLERLD ASAKVLPCQH TFCKRCLLGI VGSRNELRCP ECRTLVGSGV 60
EELPSNILLV RLLDGIKQRP WKPGPGGGSG TNCTNALRAQ SSIAANCSSK DLQSSQGGQQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-001528|E3,RING;UBD,SH3|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGATGAAT CTGCCTTGTT GGATCTTCTG GAGTGTCCTG TGTGTCTAGA GCGGCTTGAC 60
GCTTCGGCAA AGGTCTTGCC TTGCCAGCAT ACATTTTGCA AACGATGTTT GTTGGGGATT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-001528|E3,RING;UBD,SH3|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF00018--SH3_1
PF14604--SH3_9
PF00097--zf-C3HC4
PRINTS

PR00452--SH3DOMAIN
SMART

SM00184--RING
SM00326--SH3
Gene Ontology

GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0046328--P:regulation of JNK cascade
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003961 Anas platyrhynchos 79.05 0.00e+00 1183.00
IUUC-Aca-004386 Anolis carolinensis 75.25 0.00e+00 1140.00
IUUC-Ame-010659 Astyanax mexicanus 58.41 0.00e+00 870.00
IUUC-Bta-012563 Bos taurus 88.46 1.00e-105 377.00
IUUC-Cja-019730 Callithrix jacchus 88.80 0.00e+00 1298.00
IUUC-Cfa-020992 Canis familiaris 93.79 0.00e+00 1425.00
IUUC-Cpo-021304 Cavia porcellus 89.01 0.00e+00 1403.00
IUUC-Csa-023925 Chlorocebus sabaeus 90.46 0.00e+00 1333.00
IUUC-Cho-024630 Choloepus hoffmanni 82.08 0.00e+00 881.00
IUUC-Cin-025274 Ciona intestinalis 46.11 1.00e-71 262.00
IUUC-Csv-026136 Ciona savignyi 42.29 2.00e-73 269.00
IUUC-Dre-028290 Danio rerio 60.69 0.00e+00 892.00
IUUC-Dno-029083 Dasypus novemcinctus 90.63 0.00e+00 1058.00
IUUC-Dor-030388 Dipodomys ordii 95.22 0.00e+00 687.00
IUUC-Dme-032207 Drosophila melanogaster 45.90 7.00e-64 238.00
IUUC-Ete-032809 Echinops telfairi 79.14 0.00e+00 854.00
IUUC-Eca-034185 Equus caballus 91.97 0.00e+00 1134.00
IUUC-Eeu-034816 Erinaceus europaeus 77.57 0.00e+00 1147.00
IUUC-Fca-036439 Felis catus 92.85 0.00e+00 1442.00
IUUC-Fal-037074 Ficedula albicollis 78.14 0.00e+00 1148.00
IUUC-Gmo-039443 Gadus morhua 61.02 1.00e-120 427.00
IUUC-Gga-040749 Gallus gallus 82.82 0.00e+00 951.00
IUUC-Gac-041420 Gasterosteus aculeatus 74.39 3.00e-150 526.00
IUUC-Ggo-045215 Gorilla gorilla 89.66 0.00e+00 1360.00
IUUC-Hsa-046315 Homo sapiens 90.24 0.00e+00 1355.00
IUUC-Itr-048265 Ictidomys tridecemlineatus 84.41 2.00e-145 508.00
IUUC-Lch-049453 Latimeria chalumnae 70.01 0.00e+00 872.00
IUUC-Loc-052248 Lepisosteus oculatus 38.41 2.00e-75 276.00
IUUC-Laf-053651 Loxodonta africana 90.09 0.00e+00 1338.00
IUUC-Mcc-054688 Macaca mulatta 89.36 0.00e+00 1353.00
IUUC-Meu-056291 Macropus eugenii 74.93 0.00e+00 764.00
IUUC-Mga-059944 Meleagris gallopavo 76.64 0.00e+00 1162.00
IUUC-Mmr-061553 Microcebus murinus 86.95 0.00e+00 1239.00
IUUC-Mdo-062313 Monodelphis domestica 77.84 0.00e+00 1152.00
IUUC-Mmu-063516 Mus musculus 86.93 0.00e+00 1335.00
IUUC-Mpu-066064 Mustela putorius furo 92.99 0.00e+00 1404.00
IUUC-Mlu-067312 Myotis lucifugus 88.10 0.00e+00 1272.00
IUUC-Nle-069035 Nomascus leucogenys 89.55 0.00e+00 1361.00
IUUC-Opr-070690 Ochotona princeps 84.53 0.00e+00 635.00
IUUC-Ont-071484 Oreochromis niloticus 68.89 0.00e+00 725.00
IUUC-Oan-073305 Ornithorhynchus anatinus 79.32 0.00e+00 1200.00
IUUC-Ocu-074936 Oryctolagus cuniculus 88.88 0.00e+00 1374.00
IUUC-Ola-086675 Oryzias latipes 61.84 4.00e-178 618.00
IUUC-Oga-087933 Otolemur garnettii 79.87 0.00e+00 982.00
IUUC-Oar-090408 Ovis aries 88.14 3.00e-107 382.00
IUUC-Ptr-090865 Pan troglodytes 90.57 0.00e+00 1360.00
IUUC-Pan-092362 Papio anubis 90.57 0.00e+00 1333.00
IUUC-Psi-093876 Pelodiscus sinensis 78.39 0.00e+00 1169.00
IUUC-Pfo-097116 Poecilia formosa 66.04 0.00e+00 727.00
IUUC-Pab-098127 Pongo abelii 90.68 0.00e+00 1363.00
IUUC-Pca-100485 Procavia capensis 88.54 0.00e+00 1018.00
IUUC-Pva-102661 Pteropus vampyrus 88.74 0.00e+00 1282.00
IUUC-Rno-105728 Rattus norvegicus 87.64 0.00e+00 1328.00
IUUC-Sha-106515 Sarcophilus harrisii 85.37 0.00e+00 869.00
IUUC-Sar-113161 Sorex araneus 95.22 0.00e+00 671.00
IUUC-Ssc-115314 Sus scrofa 78.34 0.00e+00 1093.00
IUUC-Tgu-117012 Taeniopygia guttata 75.65 0.00e+00 1155.00
IUUC-Tru-118467 Takifugu rubripes 62.66 1.00e-162 566.00
IUUC-Tsy-119566 Tarsius syrichta 82.44 2.00e-175 609.00
IUUC-Tni-120830 Tetraodon nigroviridis 58.99 1.00e-169 590.00
IUUC-Tbe-128070 Tupaia belangeri 96.95 0.00e+00 730.00
IUUC-Ttr-128161 Tursiops truncatus 94.51 7.00e-143 501.00
IUUC-Xtr-132628 Xenopus tropicalis 72.18 0.00e+00 1060.00
Created Date 25-Jun-2017

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