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Tag Content
iUUCD ID IUUC-Fso-038160
Ensembl Protein ID NechaP66115
UniProt Accession C7Z6H2; LIS1_NECH7
Genbank Protein ID EEU40693.1
Protein Name Nuclear distribution protein PAC1; Lissencephaly-1 homolog; nudF homolog
Genbank Nucleotide ID GG698910
Gene Name C7Z6H2; PAC1; LIS1; NECHADRAFT_66115
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
NechaG66115 NechaT66115 NechaP66115
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 8.30e-46 151.7 345 378
UBD/Beta-Prp 1.70e-65 220.8 101 395
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
    gH ++v++l f ++ ++l+s sdD+ti++WDl++
   Q: 345 GHDNWVRSLVFhPSgKFLLSVSDDKTIRCWDLSQ 378
    8***********666****************976 PP
   


   UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk..ilvtgseDrtikvwdls.tgkcvhtlkghedsvlsls 101
    ++h ++i+cv+f+p +s +a+g +d+ ik+wd++ g l r+++gh+++v ++++ + +l+++s+D tik+wd+s +k ++tl gh++sv +++
   Q: 101 QSHRTPINCVAFHPIYSSIASGDEDAIIKIWDWEFGELERTVKGHTKAVLDLDYGGPKGhtLLASCSSDLTIKLWDPSdEYKNIRTLPGHDHSVSAVR 198
    56888*************************************************7655557**************887699***************** PP
   S: 102 fsp........sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtdsvyslsfd 189
    f p sg+ l+s+s+d t+r+wd+ tg+cl+ t +gh+++++ v+ + dg++l s ++Drt+rlWd+++++ +++ g h++ v++ +f
   Q: 199 FIPsgapgaplSGNLLASASRDVTVRIWDVTTGYCLK-TIRGHSDWIRDVSPSLDGKYLLSTGNDRTLRLWDISMNTPETKMvmIG-HEHCVECCAFA 294
    **99999999999************************.*******************************************99676.*********88 PP
   S: 190 sng.....................kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl.rsgdllktlqlhns 265
    + +++++gs+d+t++lwd +g+c++tl+gh+++v+s+ f+p +++l+s+s+D++ir+Wdl + g+++ktl++ ++
   Q: 295 PPTsyqhlatmaglkkappasstaEFMATGSRDKTIRLWDS-RGTCIKTLIGHDNWVRSLVFHPSGKFLLSVSDDKTIRCWDLsQEGKCVKTLEGMHE 391
    777788888999999999999999****************8.899************************************973679********996 PP
   S: 266 svis 269
    ++i
   Q: 392 HFIT 395
    6554 PP
   

Organism Fusarium solani
Functional Description
(View)

Functional Description



     Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Protein Sequence
(Fasta)
MSRTLTSRQA EELHKSIIAY LAANNFQDSV TAMRTELNLG EEIFDPATAK KYETLLEKKW 60
TSVVRLQKKT ELDSATPTSL SNRKQDPASW LPAGPPRHVL QSHRTPINCV AFHPIYSSIA 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Fso-038160|E3,WD_repeat;UBD,Beta-Prp|Fusarium solani
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGAGCCGGA CCTTGACGAG CCGGCAGGCC GAAGAGCTGT TCGTACAGGG GAGCTCCTGG 60
AGCTTGTCAC TTGCCCGTCT AACCACACTG CAGGCACAAA TCCATCATCG CATACCTCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Fso-038160|E3,WD_repeat;UBD,Beta-Prp|Fusarium solani
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR017252--Dynein_regulator_LIS1
IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005874--C:microtubule
GO:0000922--C:spindle pole
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division
GO:0006810--P:transport

KEGG nhe:NECHADRAFT_66115
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001589 Ailuropoda melanoleuca 43.96 6.00e-97 345.00
IUUC-Apl-004024 Anas platyrhynchos 44.21 5.00e-100 356.00
IUUC-Aca-004564 Anolis carolinensis 44.10 2.00e-98 350.00
IUUC-Ago-007862 Ashbya gossypii 26.53 5.00e-32 130.00
IUUC-Acl-008360 Aspergillus clavatus 65.67 2.00e-176 610.00
IUUC-Afl-008502 Aspergillus flavus 61.61 6.00e-163 565.00
IUUC-Afu-008848 Aspergillus fumigatus 66.31 0.00e+00 634.00
IUUC-Ani-009173 Aspergillus nidulans 57.05 3.00e-151 526.00
IUUC-Ang-009873 Aspergillus niger 55.87 9.00e-149 518.00
IUUC-Aor-009973 Aspergillus oryzae 62.95 1.00e-166 577.00
IUUC-Ate-010523 Aspergillus terreus 57.21 8.00e-156 541.00
IUUC-Ame-011154 Astyanax mexicanus 43.84 3.00e-99 353.00
IUUC-Bgr-011972 Blumeria graminis 64.79 0.00e+00 627.00
IUUC-Bta-013106 Bos taurus 44.10 5.00e-100 356.00
IUUC-Bci-013615 Botrytis cinerea 66.74 3.00e-179 619.00
IUUC-Cel-018459 Caenorhabditis elegans 40.09 1.00e-88 318.00
IUUC-Cja-018755 Callithrix jacchus 43.26 4.00e-97 346.00
IUUC-Cfa-020749 Canis familiaris 44.10 5.00e-100 356.00
IUUC-Cpo-022371 Cavia porcellus 44.10 5.00e-100 356.00
IUUC-Csa-023524 Chlorocebus sabaeus 45.14 1.00e-85 308.00
IUUC-Cho-024764 Choloepus hoffmanni 41.33 3.00e-79 286.00
IUUC-Cin-025753 Ciona intestinalis 44.87 9.00e-96 342.00
IUUC-Csv-025817 Ciona savignyi 43.91 5.00e-97 345.00
IUUC-Cgl-026529 Colletotrichum gloeosporioides 71.49 0.00e+00 651.00
IUUC-Cne-027087 Cryptococcus neoformans 49.14 8.00e-108 382.00
IUUC-Dre-027554 Danio rerio 43.40 4.00e-97 346.00
IUUC-Dno-029050 Dasypus novemcinctus 44.10 5.00e-100 356.00
IUUC-Dor-030222 Dipodomys ordii 40.66 5.00e-89 319.00
IUUC-Dse-031164 Dothistroma septosporum 64.79 2.00e-178 617.00
IUUC-Dme-031745 Drosophila melanogaster 43.97 2.00e-92 330.00
IUUC-Ete-032508 Echinops telfairi 46.34 2.00e-70 258.00
IUUC-Eca-034288 Equus caballus 43.41 3.00e-96 343.00
IUUC-Eeu-034984 Erinaceus europaeus 40.43 4.00e-88 316.00
IUUC-Fca-036498 Felis catus 44.10 5.00e-100 356.00
IUUC-Fal-036920 Ficedula albicollis 44.21 5.00e-100 356.00
IUUC-Fox-037996 Fusarium oxysporum 86.58 0.00e+00 829.00
IUUC-Gmo-038983 Gadus morhua 43.13 8.00e-98 348.00
IUUC-Ggr-040051 Gaeumannomyces graminis 67.17 0.00e+00 639.00
IUUC-Gga-040623 Gallus gallus 44.21 5.00e-100 356.00
IUUC-Gac-041613 Gasterosteus aculeatus 42.86 3.00e-97 347.00
IUUC-Ggo-045410 Gorilla gorilla 41.19 2.00e-81 294.00
IUUC-Hsa-046358 Homo sapiens 44.10 7.00e-100 355.00
IUUC-Itr-047890 Ictidomys tridecemlineatus 44.10 5.00e-100 356.00
IUUC-Kpa-049351 Komagataella pastoris 27.34 1.00e-42 166.00
IUUC-Lch-049936 Latimeria chalumnae 43.36 9.00e-99 352.00
IUUC-Loc-052476 Lepisosteus oculatus 43.45 3.00e-96 343.00
IUUC-Lma-053170 Leptosphaeria maculans 66.45 2.00e-172 597.00
IUUC-Laf-053713 Loxodonta africana 44.12 8.00e-98 348.00
IUUC-Mcc-054628 Macaca mulatta 44.21 9.00e-100 355.00
IUUC-Meu-055927 Macropus eugenii 39.37 8.00e-53 198.00
IUUC-Mor-056962 Magnaporthe oryzae 68.48 0.00e+00 656.00
IUUC-Mpo-057583 Magnaporthe poae 68.25 4.00e-179 619.00
IUUC-Mla-058819 Melampsora laricipopulina 46.37 5.00e-110 389.00
IUUC-Mga-059945 Meleagris gallopavo 44.21 5.00e-100 356.00
IUUC-Mvi-060403 Microbotryum violaceum 46.44 4.00e-114 403.00
IUUC-Mmr-061289 Microcebus murinus 43.60 5.00e-97 345.00
IUUC-Mdo-061912 Monodelphis domestica 43.87 4.00e-99 353.00
IUUC-Mmu-063253 Mus musculus 44.10 5.00e-100 356.00
IUUC-Mpu-066638 Mustela putorius furo 44.10 5.00e-100 356.00
IUUC-Mlu-067267 Myotis lucifugus 43.26 3.00e-97 346.00
IUUC-Nfi-068571 Neosartorya fischeri 65.22 2.00e-175 606.00
IUUC-Ncr-068895 Neurospora crassa 69.48 0.00e+00 644.00
IUUC-Nle-069087 Nomascus leucogenys 43.79 6.00e-79 285.00
IUUC-Opr-070579 Ochotona princeps 44.10 5.00e-100 356.00
IUUC-Ont-071905 Oreochromis niloticus 43.36 1.00e-98 351.00
IUUC-Oan-073072 Ornithorhynchus anatinus 44.10 5.00e-100 356.00
IUUC-Ocu-074180 Oryctolagus cuniculus 44.10 5.00e-100 356.00
IUUC-Ola-086815 Oryzias latipes 43.36 2.00e-98 350.00
IUUC-Oga-088219 Otolemur garnettii 43.26 3.00e-97 346.00
IUUC-Oar-090394 Ovis aries 44.10 5.00e-100 356.00
IUUC-Ptr-091517 Pan troglodytes 44.10 5.00e-100 356.00
IUUC-Pan-092421 Papio anubis 44.21 9.00e-100 355.00
IUUC-Psi-093370 Pelodiscus sinensis 44.21 2.00e-99 354.00
IUUC-Pma-094319 Petromyzon marinus 44.64 1.00e-83 301.00
IUUC-Pno-094815 Phaeosphaeria nodorum 66.59 9.00e-177 611.00
IUUC-Pfo-097089 Poecilia formosa 43.57 7.00e-99 352.00
IUUC-Pab-098421 Pongo abelii 44.10 5.00e-100 356.00
IUUC-Pca-100120 Procavia capensis 36.49 5.00e-58 216.00
IUUC-Pva-102960 Pteropus vampyrus 43.87 1.00e-98 351.00
IUUC-Pgr-103538 Puccinia graminis 46.62 1.00e-112 398.00
IUUC-Ptt-103990 Puccinia triticina 38.65 1.00e-34 139.00
IUUC-Pte-104261 Pyrenophora teres 67.60 1.00e-177 614.00
IUUC-Pyt-104780 Pyrenophora triticirepentis 67.60 2.00e-177 613.00
IUUC-Rno-105123 Rattus norvegicus 44.10 5.00e-100 356.00
IUUC-Sce-106208 Saccharomyces cerevisiae 27.10 6.00e-36 143.00
IUUC-Sha-107010 Sarcophilus harrisii 43.87 6.00e-99 352.00
IUUC-Sja-107899 Schizosaccharomyces japonicus 36.91 2.00e-64 238.00
IUUC-Ssl-108571 Sclerotinia sclerotiorum 68.43 2.00e-173 600.00
IUUC-Sar-113309 Sorex araneus 43.48 3.00e-95 340.00
IUUC-Sre-115003 Sporisorium reilianum 47.15 1.00e-114 404.00
IUUC-Ssc-116148 Sus scrofa 44.10 5.00e-100 356.00
IUUC-Tgu-117299 Taeniopygia guttata 44.21 6.00e-100 355.00
IUUC-Tru-118179 Takifugu rubripes 43.60 1.00e-98 351.00
IUUC-Tsy-119493 Tarsius syrichta 44.34 8.00e-99 352.00
IUUC-Tni-120355 Tetraodon nigroviridis 42.86 3.00e-96 343.00
IUUC-Tre-121977 Trichoderma reesei 64.29 2.00e-176 610.00
IUUC-Tvi-122661 Trichoderma virens 65.52 8.00e-173 598.00
IUUC-Tme-127031 Tuber melanosporum 63.52 9.00e-172 594.00
IUUC-Tbe-127492 Tupaia belangeri 40.52 1.00e-50 191.00
IUUC-Ttr-128929 Tursiops truncatus 44.10 9.00e-100 355.00
IUUC-Uma-129347 Ustilago maydis 48.16 1.00e-116 411.00
IUUC-Vda-129837 Verticillium dahliae 66.16 2.00e-176 610.00
IUUC-Vpa-130532 Vicugna pacos 38.57 6.00e-78 282.00
IUUC-Xtr-131985 Xenopus tropicalis 44.58 3.00e-100 356.00
IUUC-Xma-133314 Xiphophorus maculatus 43.33 2.00e-98 350.00
IUUC-Yli-134403 Yarrowia lipolytica 38.67 1.00e-90 325.00
Created Date 25-Jun-2017

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